{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T06:49:38Z","timestamp":1792738178315,"version":"4.5.0"},"reference-count":117,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1016\/j.neuropharm.2009.12.021","type":"journal-article","created":{"date-parts":[[2010,1,2]],"date-time":"2010-01-02T09:03:56Z","timestamp":1262423036000},"page":"877-883","source":"Crossref","is-referenced-by-count":27,"title":["De-routing neuronal precursors in the adult brain to sites of injury: Role of the vasculature"],"prefix":"10.1016","volume":"58","author":[{"given":"Mireille","family":"Massouh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armen","family":"Saghatelyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2009.12.021_bib1","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1523\/JNEUROSCI.22-03-00629.2002","article-title":"Neurogenesis in adult subventricular zone","volume":"22","author":"Alvarez-Buylla","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib2","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S0896-6273(04)00111-4","article-title":"For the long run: maintaining germinal niches in the adult brain","volume":"41","author":"Alvarez-Buylla","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib4","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1046\/j.0953-816x.2001.01611.x","article-title":"N-methyl-d-aspartate receptor-mediated increase of neurogenesis in adult rat dentate gyrus following stroke","volume":"14","author":"Arvidsson","year":"2001","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib3","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1038\/nm747","article-title":"Neuronal replacement from endogenous precursors in the adult brain after stroke","volume":"8","author":"Arvidsson","year":"2002","journal-title":"Nat. Med."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib5","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s00401-009-0483-6","article-title":"Angiogenesis after cerebral ischemia","volume":"117","author":"Beck","year":"2009","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib7","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1046\/j.1460-9568.2002.02263.x","article-title":"The rostral migratory stream in adult squirrel monkeys: contribution of new neurons to the olfactory tubercle and involvement of the antiapoptotic protein Bcl-2","volume":"16","author":"Bedard","year":"2002","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib6","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s00221-005-0233-5","article-title":"Chemical characterization of newly generated neurons in the striatum of adult primates","volume":"170","author":"Bedard","year":"2006","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib8","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.devbrainres.2004.03.021","article-title":"Evidence of newly generated neurons in the human olfactory bulb","volume":"151","author":"Bedard","year":"2004","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib9","doi-asserted-by":"crossref","first-page":"10432","DOI":"10.1073\/pnas.94.19.10432","article-title":"Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures","volume":"94","author":"Bengzon","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib10","doi-asserted-by":"crossref","first-page":"6718","DOI":"10.1523\/JNEUROSCI.21-17-06718.2001","article-title":"Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain","volume":"21","author":"Benraiss","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib11","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1097\/00004647-199906000-00007","article-title":"A potential role for erythropoietin in focal permanent cerebral ischemia in mice","volume":"19","author":"Bernaudin","year":"1999","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib12","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1111\/j.1460-9568.2007.05441.x","article-title":"Subventricular zone-derived neuroblast migration to the olfactory bulb is modulated by matrix remodelling","volume":"25","author":"Bovetti","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib13","doi-asserted-by":"crossref","first-page":"5976","DOI":"10.1523\/JNEUROSCI.0678-07.2007","article-title":"Blood vessels form a scaffold for neuroblast migration in the adult olfactory bulb","volume":"27","author":"Bovetti","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib14","doi-asserted-by":"crossref","first-page":"10526","DOI":"10.1073\/pnas.97.19.10526","article-title":"Erythropoietin crosses the blood\u2013brain barrier to protect against experimental brain injury","volume":"97","author":"Brines","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib15","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1602\/neurorx.2.3.396","article-title":"Rodent models of focal stroke: size, mechanism, and purpose","volume":"2","author":"Carmichael","year":"2005","journal-title":"NeuroRx"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib16","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1523\/JNEUROSCI.5071-04.2005","article-title":"Endothelial nitric oxide synthase regulates brain-derived neurotrophic factor expression and neurogenesis after stroke in mice","volume":"25","author":"Chen","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib17","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1523\/JNEUROSCI.1554-03.2004","article-title":"Adenovirally expressed noggin and brain-derived neurotrophic factor cooperate to induce new medium spiny neurons from resident progenitor cells in the adult striatal ventricular zone","volume":"24","author":"Chmielnicki","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib18","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0304-3940(98)00377-2","article-title":"Vascular endothelial growth factor expression in transient focal cerebral ischemia in the rat","volume":"249","author":"Cobbs","year":"1998","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib19","doi-asserted-by":"crossref","first-page":"9023","DOI":"10.1073\/pnas.1532244100","article-title":"Increased cell proliferation and neurogenesis in the adult human Huntington's disease brain","volume":"100","author":"Curtis","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib20","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.neuroscience.2004.12.051","article-title":"The distribution of progenitor cells in the subependymal layer of the lateral ventricle in the normal and Huntington's disease human brain","volume":"132","author":"Curtis","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib21","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.conb.2005.01.018","article-title":"Young and excitable: the function of new neurons in the adult mammalian brain","volume":"15","author":"Doetsch","year":"2005","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib22","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF00666035","article-title":"The role of vascular endothelial growth factor in pathological angiogenesis","volume":"36","author":"Ferrara","year":"1995","journal-title":"Breast Cancer Res. Treat."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib23","doi-asserted-by":"crossref","first-page":"13368","DOI":"10.1523\/JNEUROSCI.2918-08.2008","article-title":"Brain-derived neurotrophic factor signaling does not stimulate subventricular zone neurogenesis in adult mice and rats","volume":"28","author":"Galvao","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib24","doi-asserted-by":"crossref","first-page":"C1362","DOI":"10.1152\/ajpcell.1995.268.6.C1362","article-title":"Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents","volume":"268","author":"Gleadle","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib25","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.brainres.2003.10.034","article-title":"Migration patterns of subventricular zone cells in adult mice change after cerebral cortex injury","volume":"996","author":"Goings","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib26","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1002\/jnr.20434","article-title":"Migration and fate of newly born cells after focal cortical ischemia in adult rats","volume":"80","author":"Gotts","year":"2005","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib27","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.expneurol.2005.02.001","article-title":"Vascular changes in the subventricular zone after distal cortical lesions","volume":"194","author":"Gotts","year":"2005","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib28","doi-asserted-by":"crossref","first-page":"3168","DOI":"10.1073\/pnas.95.6.3168","article-title":"Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress","volume":"95","author":"Gould","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib29","doi-asserted-by":"crossref","first-page":"7582","DOI":"10.1073\/pnas.0801105105","article-title":"Neuroprotection via matrix-trophic coupling between cerebral endothelial cells and neurons","volume":"105","author":"Guo","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib30","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1046\/j.1460-9568.2003.02713.x","article-title":"Anterograde delivery of brain-derived neurotrophic factor to striatum via nigral transduction of recombinant adeno-associated virus increases neuronal death but promotes neurogenic response following stroke","volume":"17","author":"Gustafsson","year":"2003","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib31","doi-asserted-by":"crossref","first-page":"2710","DOI":"10.1161\/01.STR.0000096025.35225.36","article-title":"Intraventricular infusion of TrkB-Fc fusion protein promotes ischemia-induced neurogenesis in adult rat dentate gyrus","volume":"34","author":"Gustafsson","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib32","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1161\/01.STR.28.10.2039","article-title":"Rapid induction of vascular endothelial growth factor gene expression after transient middle cerebral artery occlusion in rats","volume":"28","author":"Hayashi","year":"1997","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib33","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2174\/156720206776875902","article-title":"Cerebral ischemia and angiogenesis","volume":"3","author":"Hayashi","year":"2006","journal-title":"Curr. Neurovasc. Res."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib34","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.biopsych.2003.08.013","article-title":"Electroconvulsive seizures induce endothelial cell proliferation in adult rat hippocampus","volume":"55","author":"Hellsten","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib35","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1038\/nn1265","article-title":"Dopamine depletion impairs precursor cell proliferation in Parkinson disease","volume":"7","author":"Hoglinger","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib36","doi-asserted-by":"crossref","first-page":"19761","DOI":"10.1074\/jbc.270.34.19761","article-title":"Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells","volume":"270","author":"Ikeda","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib37","doi-asserted-by":"crossref","first-page":"18117","DOI":"10.1073\/pnas.0408258102","article-title":"Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha\/CXC chemokine receptor 4 pathway","volume":"101","author":"Imitola","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib43","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0306-4522(00)00207-4","article-title":"Induction of vascular endothelial growth factor and hypoxia-inducible factor-1alpha by global ischemia in rat brain","volume":"99","author":"Jin","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib38","doi-asserted-by":"crossref","first-page":"4710","DOI":"10.1073\/pnas.081011098","article-title":"Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat","volume":"98","author":"Jin","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib41","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S1044-7431(03)00159-3","article-title":"Directed migration of neuronal precursors into the ischemic cerebral cortex and striatum","volume":"24","author":"Jin","year":"2003","journal-title":"Mol. Cell Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib39","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1073\/pnas.2634794100","article-title":"Increased hippocampal neurogenesis in Alzheimer's disease","volume":"101","author":"Jin","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib40","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/00004647-200404000-00005","article-title":"Post-ischemic administration of heparin-binding epidermal growth factor-like growth factor (HB-EGF) reduces infarct size and modifies neurogenesis after focal cerebral ischemia in the rat","volume":"24","author":"Jin","year":"2004","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib42","doi-asserted-by":"crossref","first-page":"13198","DOI":"10.1073\/pnas.0603512103","article-title":"Evidence for stroke-induced neurogenesis in the human brain","volume":"103","author":"Jin","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib44","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0959-4388(03)00017-5","article-title":"Neurogenesis after ischaemic brain insults","volume":"13","author":"Kokaia","year":"2003","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib45","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1038\/sj.jcbfm.9600402","article-title":"Growth factor-stimulated generation of new cortical tissue and functional recovery after stroke damage to the motor cortex of rats","volume":"27","author":"Kolb","year":"2007","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib46","doi-asserted-by":"crossref","first-page":"5768","DOI":"10.1073\/pnas.96.10.5768","article-title":"Continuation of neurogenesis in the hippocampus of the adult macaque monkey","volume":"96","author":"Kornack","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib47","doi-asserted-by":"crossref","first-page":"4752","DOI":"10.1073\/pnas.081074998","article-title":"The generation, migration, and differentiation of olfactory neurons in the adult primate brain","volume":"98","author":"Kornack","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib48","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1161\/01.STR.27.10.1865","article-title":"VEGF and flt. Expression time kinetics in rat brain infarct","volume":"27","author":"Kovacs","year":"1996","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/exnr.2002.7992","article-title":"Suppression of insult-induced neurogenesis in adult rat brain by brain-derived neurotrophic factor","volume":"177","author":"Larsson","year":"2002","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib50","doi-asserted-by":"crossref","first-page":"3491","DOI":"10.1523\/JNEUROSCI.4085-05.2006","article-title":"Involvement of matrix metalloproteinase in neuroblast cell migration from the subventricular zone after stroke","volume":"26","author":"Lee","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib51","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1097\/00005072-199809000-00009","article-title":"Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) following permanent and transient occlusion of the middle cerebral artery in the rat","volume":"57","author":"Lennmyr","year":"1998","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib52","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1006\/mcne.1999.0762","article-title":"Endothelial trophic support of neuronal production and recruitment from the adult mammalian subependyma","volume":"13","author":"Leventhal","year":"1999","journal-title":"Mol. Cell Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/sj.jcbfm.9600170","article-title":"Adult neurogenesis and the ischemic forebrain","volume":"26","author":"Lichtenwalner","year":"2006","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"Suppl","key":"10.1016\/j.neuropharm.2009.12.021_bib54","doi-asserted-by":"crossref","first-page":"S42","DOI":"10.1038\/nm1064","article-title":"Stem cell therapy for human neurodegenerative disorders-how to make it work","volume":"10","author":"Lindvall","year":"2004","journal-title":"Nat. Med."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib55","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0169-328X(99)00295-8","article-title":"Cell death in regenerating populations of neurons in BDNF mutant mice","volume":"75","author":"Linnarsson","year":"2000","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib56","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1038\/sj.jcbfm.9600371","article-title":"Stroke induces gene profile changes associated with neurogenesis and angiogenesis in adult subventricular zone progenitor cells","volume":"27","author":"Liu","year":"2007","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib57","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/S0896-6273(02)00722-5","article-title":"Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain","volume":"34","author":"Louissaint","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib58","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0896-6273(93)90281-U","article-title":"Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone","volume":"11","author":"Luskin","year":"1993","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib59","doi-asserted-by":"crossref","first-page":"13114","DOI":"10.1523\/JNEUROSCI.4667-06.2006","article-title":"Increased generation of neuronal progenitors after ischemic injury in the aged adult human forebrain","volume":"26","author":"Macas","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib61","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1111\/j.1460-9568.1996.tb01252.x","article-title":"Erythropoietin gene expression in human, monkey and murine brain","volume":"8","author":"Marti","year":"1996","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib62","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/S0002-9440(10)64964-4","article-title":"Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia","volume":"156","author":"Marti","year":"2000","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib60","doi-asserted-by":"crossref","first-page":"15809","DOI":"10.1073\/pnas.95.26.15809","article-title":"Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors","volume":"95","author":"Marti","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib63","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1161\/01.STR.0000070840.56414.3B","article-title":"Adenovirus-mediated gene transfer of fibroblast growth factor-2 increases BrdU-positive cells after forebrain ischemia in gerbils","volume":"34","author":"Matsuoka","year":"2003","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib64","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1146\/annurev.neuro.28.051804.101459","article-title":"Adult neurogenesis in the mammalian central nervous system","volume":"28","author":"Ming","year":"2005","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib65","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1172\/JCI1560","article-title":"Nitric oxide synthase modulates angiogenesis in response to tissue ischemia","volume":"101","author":"Murohara","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib66","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S0092-8674(02)00862-0","article-title":"Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors","volume":"110","author":"Nakatomi","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib67","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1177\/1073858407309545","article-title":"Poststroke neurogenesis: emerging principles of migration and localization of immature neurons","volume":"14","author":"Ohab","year":"2008","journal-title":"Neuroscientist"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib68","doi-asserted-by":"crossref","first-page":"13007","DOI":"10.1523\/JNEUROSCI.4323-06.2006","article-title":"A neurovascular niche for neurogenesis after stroke","volume":"26","author":"Ohab","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib69","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/1096-9861(20001002)425:4<479::AID-CNE2>3.0.CO;2-3","article-title":"Vascular niche for adult hippocampal neurogenesis","volume":"425","author":"Palmer","year":"2000","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib70","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1177\/1073858403252680","article-title":"Injury-induced neurogenesis in the adult mammalian brain","volume":"9","author":"Parent","year":"2003","journal-title":"Neuroscientist"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib73","doi-asserted-by":"crossref","first-page":"3727","DOI":"10.1523\/JNEUROSCI.17-10-03727.1997","article-title":"Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus","volume":"17","author":"Parent","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib71","doi-asserted-by":"crossref","first-page":"3174","DOI":"10.1523\/JNEUROSCI.22-08-03174.2002","article-title":"Prolonged seizures increase proliferating neuroblasts in the adult rat subventricular zone-olfactory bulb pathway","volume":"22","author":"Parent","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib72","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1002\/ana.10393","article-title":"Rat forebrain neurogenesis and striatal neuron replacement after focal stroke","volume":"52","author":"Parent","year":"2002","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib74","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/exnr.2001.7768","article-title":"Neurogenesis in the subventricular zone and rostral migratory stream of the neonatal and adult primate forebrain","volume":"172","author":"Pencea","year":"2001","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib75","doi-asserted-by":"crossref","first-page":"6706","DOI":"10.1523\/JNEUROSCI.21-17-06706.2001","article-title":"Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus","volume":"21","author":"Pencea","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib76","doi-asserted-by":"crossref","first-page":"13211","DOI":"10.1073\/pnas.192314199","article-title":"Experimental autoimmune encephalomyelitis mobilizes neural progenitors from the subventricular zone to undergo oligodendrogenesis in adult mice","volume":"99","author":"Picard-Riera","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib77","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1097\/00005072-199906000-00010","article-title":"Cell type specific upregulation of vascular endothelial growth factor in an MCA-occlusion model of cerebral infarct","volume":"58","author":"Plate","year":"1999","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib78","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/sj.jcbfm.9600172","article-title":"Stromal cell-derived factor 1alpha mediates neural progenitor cell motility after focal cerebral ischemia","volume":"26","author":"Robin","year":"2006","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib79","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1172\/JCI1699","article-title":"Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling","volume":"101","author":"Rudic","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib80","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.semcdb.2009.04.006","article-title":"Role of blood vessels in the neuronal migration","volume":"20","author":"Saghatelyan","year":"2009","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib81","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nn1211","article-title":"Tenascin-R mediates activity-dependent recruitment of neuroblasts in the adult mouse forebrain","volume":"7","author":"Saghatelyan","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib82","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1161\/STROKEAHA.106.477331","article-title":"Intravenous brain-derived neurotrophic factor enhances poststroke sensorimotor recovery and stimulates neurogenesis","volume":"38","author":"Schabitz","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib83","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1007\/978-1-4757-6376-8_14","article-title":"Functional implications of seizure-induced neurogenesis","volume":"548","author":"Scharfman","year":"2004","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib84","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0165-3806(01)00286-3","article-title":"Neurogenesis following brain ischemia","volume":"134","author":"Sharp","year":"2002","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib85","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1126\/science.1095505","article-title":"Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells","volume":"304","author":"Shen","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib86","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.stem.2008.07.026","article-title":"Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell\u2013cell interactions","volume":"3","author":"Shen","year":"2008","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib87","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.neulet.2009.08.049","article-title":"Adenovirus-mediated brain-derived neurotrophic factor expression regulated by hypoxia response element protects brain from injury of transient middle cerebral artery occlusion in mice","volume":"465","author":"Shi","year":"2009","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib88","doi-asserted-by":"crossref","first-page":"9733","DOI":"10.1523\/JNEUROSCI.21-24-09733.2001","article-title":"Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells","volume":"21","author":"Shingo","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib89","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/359843a0","article-title":"Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis","volume":"359","author":"Shweiki","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib90","doi-asserted-by":"crossref","first-page":"4172","DOI":"10.1523\/JNEUROSCI.4956-08.2009","article-title":"Vasculature guides migrating neuronal precursors in the adult mammalian forebrain via brain-derived neurotrophic factor signaling","volume":"29","author":"Snapyan","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib91","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1172\/JCI200317977","article-title":"VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia","volume":"111","author":"Sun","year":"2003","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib92","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.stem.2008.07.025","article-title":"A specialized vascular niche for adult neural stem cells","volume":"3","author":"Tavazoie","year":"2008","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib93","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1038\/sj.jcbfm.9600573","article-title":"Coupling of angiogenesis and neurogenesis in cultured endothelial cells and neural progenitor cells after stroke","volume":"28","author":"Teng","year":"2008","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib94","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1172\/JCI200317170","article-title":"EGF amplifies the replacement of parvalbumin-expressing striatal interneurons after ischemia","volume":"111","author":"Teramoto","year":"2003","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib95","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1634\/stemcells.2005-0281","article-title":"Persistent production of neurons from adult brain stem cells during recovery after stroke","volume":"24","author":"Thored","year":"2006","journal-title":"Stem Cells"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib96","doi-asserted-by":"crossref","first-page":"3032","DOI":"10.1161\/STROKEAHA.107.488445","article-title":"Long-term neuroblast migration along blood vessels in an area with transient angiogenesis and increased vascularization after stroke","volume":"38","author":"Thored","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib97","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1523\/JNEUROSCI.4480-05.2006","article-title":"A critical role of erythropoietin receptor in neurogenesis and post-stroke recovery","volume":"26","author":"Tsai","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib98","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1038\/4151030a","article-title":"Functional neurogenesis in the adult hippocampus","volume":"415","author":"van Praag","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib99","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1111\/j.1460-9568.2006.04682.x","article-title":"Secretion of brain-derived neurotrophic factor from brain microvascular endothelial cells","volume":"23","author":"Wang","year":"2006","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib100","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1161\/01.STR.0000132196.49028.a4","article-title":"Treatment of stroke with erythropoietin enhances neurogenesis and angiogenesis and improves neurological function in rats","volume":"35","author":"Wang","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib101","doi-asserted-by":"crossref","first-page":"5996","DOI":"10.1523\/JNEUROSCI.5380-05.2006","article-title":"Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migration","volume":"26","author":"Wang","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib102","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1002\/jnr.21169","article-title":"VEGF-overexpressing transgenic mice show enhanced post-ischemic neurogenesis and neuromigration","volume":"85","author":"Wang","year":"2007","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib103","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.expneurol.2005.08.028","article-title":"Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb","volume":"197","author":"Winner","year":"2006","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib104","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1126\/science.1099344","article-title":"Neuroscience. Cellular interactions in the stem cell niche","volume":"304","author":"Wurmser","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib105","doi-asserted-by":"crossref","first-page":"6627","DOI":"10.1523\/JNEUROSCI.0149-06.2006","article-title":"Subventricular zone-derived neuroblasts migrate and differentiate into mature neurons in the post-stroke adult striatum","volume":"26","author":"Yamashita","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib106","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/cne.20659","article-title":"A disintegrin and metalloprotease 21 (ADAM21) is associated with neurogenesis and axonal growth in developing and adult rodent CNS","volume":"490","author":"Yang","year":"2005","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib107","doi-asserted-by":"crossref","first-page":"5146","DOI":"10.1523\/JNEUROSCI.0654-07.2007","article-title":"p75 neurotrophin receptor expression defines a population of BDNF-responsive neurogenic precursor cells","volume":"27","author":"Young","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib114","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1172\/JCI9369","article-title":"VEGF enhances angiogenesis and promotes blood\u2013brain barrier leakage in the ischemic brain","volume":"106","author":"Zhang","year":"2000","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib113","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0306-4522(01)00117-8","article-title":"Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia","volume":"105","author":"Zhang","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib111","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0306-4522(02)00696-6","article-title":"Migration and differentiation of adult rat subventricular zone progenitor cells transplanted into the adult rat striatum","volume":"116","author":"Zhang","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib108","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/00004647-200404000-00009","article-title":"Activated neural stem cells contribute to stroke-induced neurogenesis and neuroblast migration toward the infarct boundary in adult rats","volume":"24","author":"Zhang","year":"2004","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib109","doi-asserted-by":"crossref","first-page":"5810","DOI":"10.1523\/JNEUROSCI.1109-04.2004","article-title":"Stroke transiently increases subventricular zone cell division from asymmetric to symmetric and increases neuronal differentiation in the adult rat","volume":"24","author":"Zhang","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib112","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1177\/1073858405278865","article-title":"Neurogenesis in the adult ischemic brain: generation, migration, survival, and restorative therapy","volume":"11","author":"Zhang","year":"2005","journal-title":"Neuroscientist"},{"key":"10.1016\/j.neuropharm.2009.12.021_bib110","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1038\/jcbfm.2009.55","article-title":"Patterns and dynamics of subventricular zone neuroblast migration in the ischemic striatum of the adult mouse","volume":"29","author":"Zhang","year":"2009","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib115","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1159\/000092093","article-title":"Mitogen-activated protein kinase signaling, oxygen sensors and hypoxic induction of neurogenesis","volume":"3","author":"Zhou","year":"2006","journal-title":"Neurodegener. Dis."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib116","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2005.04.075","article-title":"Neurogenesis in the adult rat brain after intermittent hypoxia","volume":"1055","author":"Zhu","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2009.12.021_bib117","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1006\/mcne.1998.0684","article-title":"Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb","volume":"11","author":"Zigova","year":"1998","journal-title":"Mol. Cell Neurosci."}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390809003992?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390809003992?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T21:58:44Z","timestamp":1558735124000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390809003992"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":117,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["S0028390809003992"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2009.12.021","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2010,5]]}}}