{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:47:28Z","timestamp":1791308848608,"version":"4.3.1"},"reference-count":80,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":562,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100002428","name":"Austrian Science Fund (FWF)","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002428","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1016\/j.neuropharm.2011.07.027","type":"journal-article","created":{"date-parts":[[2011,8,6]],"date-time":"2011-08-06T20:25:44Z","timestamp":1312662344000},"page":"304-312","source":"Crossref","is-referenced-by-count":131,"title":["Magnesium deficiency induces anxiety and HPA axis dysregulation: Modulation by therapeutic drug treatment"],"prefix":"10.1016","volume":"62","author":[{"given":"S.B.","family":"Sartori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Whittle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Hetzenauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Singewald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2011.07.027_bib1","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1176\/appi.ajp.161.8.1488","article-title":"Low-dose cortisol for symptoms of posttraumatic stress disorder","volume":"161","author":"Aerni","year":"2004","journal-title":"Am. J. Psychiatry"},{"issue":"Suppl. 1","key":"10.1016\/j.neuropharm.2011.07.027_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1468-1331.2005.01202.x","article-title":"Cost of disorders of the brain in Europe","volume":"12","author":"Andlin-Sobocki","year":"2005","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib3","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1007\/s10067-006-0348-5","article-title":"Vitamin D deficiency is associated with anxiety and depression in fibromyalgia","volume":"26","author":"Armstrong","year":"2007","journal-title":"Clin. Rheumatol."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib4","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1176\/ajp.156.4.585","article-title":"Serial CSF corticotropin-releasing hormone levels and adrenocortical activity in combat veterans with posttraumatic stress disorder","volume":"156","author":"Baker","year":"1999","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib5","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1523\/JNEUROSCI.15-01-00709.1995","article-title":"Conditioned fear-induced changes in behavior and in the expression of the immediate early gene c-fos: with and without diazepam pretreatment","volume":"15","author":"Beck","year":"1995","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib6","first-page":"1108","article-title":"Rodent models of anxiety-like behaviors: are they predictive for compounds acting via non-benzodiazepine mechanisms?","volume":"2","author":"Belzung","year":"2001","journal-title":"Curr. Opin. Investig. Drugs"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib7","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0166-4328(01)00291-1","article-title":"Measuring normal and pathological anxiety-like behaviour in mice: a review","volume":"125","author":"Belzung","year":"2001","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib8","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.janxdis.2009.10.011","article-title":"Enhancing exposure therapy for anxiety disorders with glucocorticoids: from basic mechanisms of emotional learning to clinical applications","volume":"24","author":"Bentz","year":"2010","journal-title":"J.\u00a0Anxiety Disord."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib9","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/BF00181937","article-title":"The effects of chronic antidepressant treatment in an animal model of anxiety","volume":"95","author":"Bodnoff","year":"1988","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib10","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/BF00442264","article-title":"A\u00a0comparison of the effects of diazepam versus several typical and atypical anti-depressant drugs in an animal model of anxiety","volume":"97","author":"Bodnoff","year":"1989","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib11","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.1460-9568.2005.04576.x","article-title":"Prenatal stress: opposite effects on anxiety and hypothalamic expression of vasopressin and corticotropin-releasing hormone in rats selectively bred for high and low anxiety","volume":"23","author":"Bosch","year":"2006","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib12","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.neubiorev.2006.02.002","article-title":"The stress-induced hyperthermia paradigm as a physiological animal model for anxiety: a review of pharmacological and genetic studies in the mouse","volume":"31","author":"Bouwknecht","year":"2007","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib13","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1176\/ajp.154.5.624","article-title":"Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder","volume":"154","author":"Bremner","year":"1997","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib14","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0003-3472(61)90001-X","article-title":"Analysis of maternal effects in the inheritance of behavior","volume":"9","author":"Broadhurst","year":"1961","journal-title":"Anim. Behav."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib15","first-page":"1","article-title":"CaV1.3 L-type Ca2+ channels modulate depression-like behaviour in mice independent of deaf phenotype","author":"Busquet","year":"2009","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib16","series-title":"Neuropsychopharmacology \u2013 5th Generation of Progress","article-title":"Neurobiological basis of anxiety disorders","author":"Charney","year":"2008"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib17","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1177\/0269881105048899","article-title":"Treatment of depression: time to consider folic acid and vitamin B12","volume":"19","author":"Coppen","year":"2005","journal-title":"J.\u00a0Psychopharmacol."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib18","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/0091-3057(81)90007-1","article-title":"Neuropharmacologic specificity of a simple animal model for the behavioral actions of benzodiazepines","volume":"15","author":"Crawley","year":"1981","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib19","series-title":"What\u2019s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice","author":"Crawley","year":"2000"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib20","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1038\/nrd1825","article-title":"The ascent of mouse: advances in modelling human depression and anxiety","volume":"4","author":"Cryan","year":"2005","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib21","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1038\/sj.npp.1300694","article-title":"Stress-induced c-Fos expression is differentially modulated by dexamethasone, diazepam and imipramine","volume":"30","author":"de Medeiros","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib22","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0091-6773(74)90800-1","article-title":"Response to 20 generations of selection for open-field activity in mice","volume":"11","author":"DeFries","year":"1974","journal-title":"Behav. Biol."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib23","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.neubiorev.2005.03.017","article-title":"Recent advances in animal models of chronic antidepressant effects: the novelty-induced hypophagia test","volume":"29","author":"Dulawa","year":"2005","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib24","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1038\/sj.npp.1300433","article-title":"Effects of chronic fluoxetine in animal models of anxiety and depression","volume":"29","author":"Dulawa","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib25","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.biopha.2008.02.007","article-title":"Neuroprotective gene profile in the brain of magnesium-deficient mice","volume":"62","author":"German-Fattal","year":"2008","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib26","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.ejphar.2006.10.028","article-title":"Antidepressant-induced undesirable weight gain: prevention with rimonabant without interference with behavioral effectiveness","volume":"554","author":"Gobshtis","year":"2007","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib27","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1146\/annurev.neuro.27.070203.144212","article-title":"Genetic approaches to the study of anxiety","volume":"27","author":"Gordon","year":"2004","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib28","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s002130050038","article-title":"Differences in anxiety-related behaviours and in sensitivity to diazepam in inbred and outbred strains of mice","volume":"148","author":"Griebel","year":"2000","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib29","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.neuropharm.2011.02.009","article-title":"Characterization of 5-HT(1A\/1B)\u2212\/\u2212 mice: an animal model sensitive to anxiolytic treatments","volume":"61","author":"Guilloux","year":"2011","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib30","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1258\/002367700780578055","article-title":"Euthanasia of rats with carbon dioxide \u2013 animal welfare aspects","volume":"34","author":"Hackbarth","year":"2000","journal-title":"Lab. Anim."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib31","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.pneurobio.2005.10.008","article-title":"N-methyl-d-aspartate (NMDA) and the regulation of mitogen-activated protein kinase (MAPK) signaling pathways: a revolving neurochemical axis for therapeutic intervention?","volume":"77","author":"Haddad","year":"2005","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib32","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.physbeh.2010.04.027","article-title":"Repeated social defeat stress induces chronic hyperthermia in rats","volume":"101","author":"Hayashida","year":"2010","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib33","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1055\/s-2002-33195","article-title":"Oral Mg(2+) supplementation reverses age-related neuroendocrine and sleep EEG changes in humans","volume":"35","author":"Held","year":"2002","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib34","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0893-133X(00)00159-7","article-title":"The corticosteroid receptor hypothesis of depression","volume":"23","author":"Holsboer","year":"2000","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib35","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0169-328X(95)00086-8","article-title":"Chlordiazepoxide attenuates stress-induced activation of neurons, corticotropin-releasing factor (CRF) gene transcription and CRF biosynthesis in the paraventricular nucleus (PVN)","volume":"32","author":"Imaki","year":"1995","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib36","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1080\/00048670802534408","article-title":"Association between magnesium intake and depression and anxiety in community-dwelling adults: the Hordaland health study","volume":"43","author":"Jacka","year":"2009","journal-title":"Aust. N. Z. J. Psychiatry"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib37","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0014-5793(85)80994-7","article-title":"Cloning and sequence analysis of cDNA for rat corticotropin-releasing factor precursor","volume":"191","author":"Jingami","year":"1985","journal-title":"FEBS Lett."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib38","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1037\/0735-7044.102.2.304","article-title":"Magnesium deficiency alters aggressive behavior and catecholamine function","volume":"102","author":"Kantak","year":"1988","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib39","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1111\/j.1471-4159.2004.02953.x","article-title":"Differences in serotonergic neurotransmission between rats displaying high or low anxiety\/depression-like behaviour: effects of chronic paroxetine treatment","volume":"92","author":"Keck","year":"2005","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib40","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1210\/endo.134.6.8194481","article-title":"Differential expression of corticotropin-releasing hormone in developing mouse embryos and adult brain","volume":"134","author":"Keegan","year":"1994","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib41","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0031-9384(01)00541-8","article-title":"Alterations in core body temperature, locomotor activity, and corticosterone following acute and repeated social defeat of male NMRI mice","volume":"74","author":"Keeney","year":"2001","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib42","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1001\/archpsyc.62.6.593","article-title":"Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the national comorbidity survey replication","volume":"62","author":"Kessler","year":"2005","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib43","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1097\/YCO.0b013e3282f08759","article-title":"New directions in the conceptualization of psychotic disorders","volume":"20","author":"Kroll","year":"2007","journal-title":"Curr. Opin. Psychiatry"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib44","doi-asserted-by":"crossref","first-page":"4375","DOI":"10.1523\/JNEUROSCI.0115-05.2005","article-title":"Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety","volume":"25","author":"Kromer","year":"2005","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib45","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.physbeh.2010.10.019","article-title":"Behavioral characterization of A\/J and C57BL\/6J mice using a multidimensional test: association between blood plasma and brain magnesium-ion concentration with anxiety","volume":"102","author":"Laarakker","year":"2011","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib46","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/BF02244136","article-title":"Pharmacological validation of a novel animal model of anticipatory anxiety in mice","volume":"101","author":"Lecci","year":"1990","journal-title":"Psychopharmacology (Berl.)"},{"issue":"Suppl. 13","key":"10.1016\/j.neuropharm.2011.07.027_bib47","first-page":"5","article-title":"Panic disorder as a chronic illness","volume":"58","author":"Liebowitz","year":"1997","journal-title":"J.\u00a0Clin. Psychiatry"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib48","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0893-133X(98)00042-6","article-title":"Behavioral, physiological, and neuroendocrine stress responses and differential sensitivity to diazepam in two Wistar rat lines selectively bred for high- and low-anxiety-related behavior","volume":"19","author":"Liebsch","year":"1998","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib49","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ygcen.2005.12.006","article-title":"Regulation of behavioral responses by corticotropin-releasing factor","volume":"146","author":"Lowry","year":"2006","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib50","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/S0006-3223(02)01827-9","article-title":"Validation of a simple, ethologically relevant paradigm for assessing anxiety in mice","volume":"54","author":"Merali","year":"2003","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib51","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0301-0082(03)00087-X","article-title":"The neurobiology and control of anxious states","volume":"70","author":"Millan","year":"2003","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib52","doi-asserted-by":"crossref","first-page":"e5346","DOI":"10.1371\/journal.pone.0005346","article-title":"Differential stress-induced neuronal activation patterns in mouse lines selectively bred for high, normal or low anxiety","volume":"4","author":"Muigg","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib53","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1080\/1028415021000039194","article-title":"Magnesium and affective disorders","volume":"5","author":"Murck","year":"2002","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib54","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s002130050617","article-title":"Mg2+ reduces ACTH secretion and enhances spindle power without changing delta power during sleep in men \u2013 possible therapeutic implications","volume":"137","author":"Murck","year":"1998","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib55","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.neures.2008.09.009","article-title":"Enhanced susceptibility to MPTP neurotoxicity in magnesium-deficient C57BL\/6N mice","volume":"63","author":"Muroyama","year":"2009","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib56","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/syn.20597","article-title":"Effect of neuropeptide Y Y2 receptor deletion on emotional stress-induced neuronal activation in mice","volume":"63","author":"Nguyen","year":"2009","journal-title":"Synapse"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib57","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.bbr.2010.04.038","article-title":"Restraint stress-induced brain activation patterns in two strains of mice differing in their anxiety behaviour","volume":"213","author":"O\u2019Mahony","year":"2010","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib58","series-title":"The Mouse Brain in Stereotaxic Coordinates","author":"Paxinos","year":"2001"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib59","first-page":"185","article-title":"Pharmakotherapie bei Angsterkrankungen","volume":"57","author":"Plag","year":"2009","journal-title":"Z.\u00a0Psychiatr. Psychol. Psychother."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib60","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.pbb.2004.01.006","article-title":"Antidepressant- and anxiolytic-like activity of magnesium in mice","volume":"78","author":"Poleszak","year":"2004","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib61","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1093\/ajcn\/84.2.289","article-title":"Global nutrition dynamics: the world is shifting rapidly toward a diet linked with noncommunicable diseases","volume":"84","author":"Popkin","year":"2006","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib62","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.biopsych.2003.10.021","article-title":"Neurobiological correlates of high (HAB) versus low anxiety-related behavior (LAB): differential Fos expression in HAB and LAB rats","volume":"55","author":"Salome","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib63","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1126\/science.1083328","article-title":"Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants","volume":"301","author":"Santarelli","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib64","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/j.neuropharm.2004.02.013","article-title":"Evaluation of the effect of chronic antidepressant treatment on neurokinin-1 receptor expression in the rat brain","volume":"46","author":"Sartori","year":"2004","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib65","doi-asserted-by":"crossref","first-page":"531","DOI":"10.2217\/fnl.11.34","article-title":"The clinical implications of mouse models of enhanced anxiety","volume":"6","author":"Sartori","year":"2011","journal-title":"Future Neurol"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib66","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1080\/07315724.1994.10718432","article-title":"Consequences of magnesium deficiency on the enhancement of stress reactions; preventive and therapeutic implications (a review)","volume":"13","author":"Seelig","year":"1994","journal-title":"J.\u00a0Am. Coll. Nutr."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib67","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0006-3223(02)01574-3","article-title":"Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs","volume":"53","author":"Singewald","year":"2003","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib68","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.neuropharm.2004.08.010","article-title":"Magnesium-deficient diet\u00a0alters depression- and anxiety-related behavior in mice \u2013 influence of desipramine and Hypericum perforatum extract","volume":"47","author":"Singewald","year":"2004","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib69","doi-asserted-by":"crossref","first-page":"5585","DOI":"10.1073\/pnas.0509184103","article-title":"Glucocorticoids reduce phobic fear in humans","volume":"103","author":"Soravia","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib70","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1080\/07315724.2000.10718920","article-title":"Micronutrients and the premenstrual syndrome: the case for calcium","volume":"19","author":"Thys-Jacobs","year":"2000","journal-title":"J.\u00a0Am. Coll. Nutr."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib71","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1046\/j.1460-9568.2003.02725.x","article-title":"Reduced anxiety and improved stress coping ability in mice lacking NPY-Y2 receptors","volume":"18","author":"Tschenett","year":"2003","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib72","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0018-506X(02)00013-2","article-title":"Differences in basal and stress-induced HPA regulation of wild house mice selected for high and low aggression","volume":"43","author":"Veenema","year":"2003","journal-title":"Horm. Behav."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib73","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.ejphar.2008.02.097","article-title":"Translational aspects of pharmacological research into anxiety disorders: the stress-induced hyperthermia (SIH) paradigm","volume":"585","author":"Vinkers","year":"2008","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib74","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1007\/s00726-010-0758-1","article-title":"Changes in brain protein expression are linked to magnesium restriction-induced depression-like behavior","volume":"40","author":"Whittle","year":"2011","journal-title":"Amino Acids"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib75","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s00726-008-0195-6","article-title":"Zinc deficiency induces enhanced depression-like behaviour and altered limbic activation reversed by antidepressant treatment in mice","volume":"36","author":"Whittle","year":"2009","journal-title":"Amino Acids"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib76","unstructured":"WHO, 2004. Global burden of disease report."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib77","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ejphar.2005.03.029","article-title":"Effects of desipramine and tramadol in a chronic mild stress model in mice are altered by yohimbine but not by pindolol","volume":"514","author":"Yalcin","year":"2005","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2011.07.027_bib78","series-title":"Handbook of Anxiety and Fear","first-page":"455","article-title":"Stress hormones and anxiety disorders","author":"Young","year":"2008"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib79","first-page":"1477","article-title":"What to do when SSRIs fail: eight strategies for optimizing treatment of panic disorder","volume":"66","author":"Zamorski","year":"2002","journal-title":"Am. Fam. Physician"},{"key":"10.1016\/j.neuropharm.2011.07.027_bib80","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.cnur.2009.06.002","article-title":"Women\u2019s mental health: depression and anxiety","volume":"44","author":"Zender","year":"2009","journal-title":"Nurs. Clin. North Am."}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390811003054?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390811003054?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T15:36:32Z","timestamp":1686238592000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390811003054"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":80,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["S0028390811003054"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2011.07.027","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}