{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T18:17:10Z","timestamp":1761848230277,"version":"build-2065373602"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1016\/j.neuropharm.2012.03.010","type":"journal-article","created":{"date-parts":[[2012,3,27]],"date-time":"2012-03-27T20:47:56Z","timestamp":1332881276000},"page":"143-150","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Constitutively active group I mGlu receptors and PKMzeta regulate synaptic transmission in developing perirhinal cortex"],"prefix":"10.1016","volume":"66","author":[{"given":"Isabella","family":"Panaccione","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"King","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gemma","family":"Molinaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Riozzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Battaglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferdinando","family":"Nicoletti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zafar I.","family":"Bashir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2012.03.010_bib1","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1152\/jn.90476.2008","article-title":"AMPA silencing is a prerequisite for developmental long-term potentiation in the hippocampal CA1 region","volume":"100","author":"Abrahamsson","year":"2008","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib2","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1113\/jphysiol.2009.178798","article-title":"Early NMDA receptor-driven waves of activity in the developing neocortex: physiological or pathological network oscillations?","volume":"588","author":"Allene","year":"2010","journal-title":"J.\u00a0Physiol."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib3","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.jneumeth.2006.12.018","article-title":"Capabilities of the WinLTP data acquisition program extending beyond basic LTP experimental functions","volume":"162","author":"Anderson","year":"2007","journal-title":"J.\u00a0Neurosci. Methods"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib4","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1038\/35082096","article-title":"Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer","volume":"411","author":"Ango","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib5","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.tins.2004.04.009","article-title":"The mGluR theory of fragile X mental retardation","volume":"27","author":"Bear","year":"2004","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib6","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1152\/physrev.00017.2006","article-title":"GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations","volume":"87","author":"Ben-Ari","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib7","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1098\/rstb.2002.1097","article-title":"Evidence concerning how neurons of the perirhinal cortex may effect familiarity discrimination","volume":"357","author":"Brown","year":"2002","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib8","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.yexcr.2004.06.013","article-title":"Mutual regulation between metabotropic glutamate type 1alpha receptor and caveolin proteins: from traffick to constitutive activity","volume":"300","author":"Burgue\u00f1o","year":"2004","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib9","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/j.1460-9568.1997.tb01348.x","article-title":"Expression and coupling to polyphosphoinositide hydrolysis of group I metabotropic Glutamate receptors in early postnatal and adult rat brain","volume":"9","author":"Casabona","year":"1997","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib10","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1113\/jphysiol.2007.150029","article-title":"The regulation of dendritic arbor development and plasticity by glutamatergic synaptic input: a review of the synaptotrophic hypothesis","volume":"586","author":"Cline","year":"2008","journal-title":"J.\u00a0Physiol."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib11","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.euroneuro.2009.12.006","article-title":"Mapping the brain pathways of traumatic memory: inactivation of protein kinase M zeta in different brain regions disrupts traumatic memory processes and attenuates traumatic stress responses in rats","volume":"20","author":"Cohen","year":"2010","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib12","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1152\/jn.00221.2006","article-title":"Early postnatal plasticity in neocortex of Fmr1 knockout mice","volume":"96","author":"Desai","year":"2006","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib13","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.neuron.2007.12.001","article-title":"Correction of fragile X syndrome in mice","volume":"56","author":"D\u00f6len","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib14","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/nn820","article-title":"Memory enhancement and formation by atypical PKM activity in Drosophila melanogaster","volume":"5","author":"Drier","year":"2002","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib15","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/nm1788","article-title":"Reversal of learning deficits in a Tsc2+\/\u2212 mouse model of tuberous sclerosis","volume":"14","author":"Ehninger","year":"2008","journal-title":"Nat. Med."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib16","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/74823","article-title":"Large-scale oscillatory calcium waves in the immature cortex","volume":"3","author":"Garaschuk","year":"2000","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib17","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1073\/pnas.0304699101","article-title":"Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors","volume":"101","author":"Goudet","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib18","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.neuron.2008.02.022","article-title":"Expression of long-term depression underlies visual recognition memory","volume":"58","author":"Griffiths","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib19","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.tins.2006.01.005","article-title":"AMPA signalling in nascent glutamatergic synapses: there and not there!","volume":"29","author":"Groc","year":"2006","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib20","doi-asserted-by":"crossref","first-page":"12127","DOI":"10.1073\/pnas.0602670103","article-title":"AMPA receptors regulate experience-dependent dendritic arbor growth in\u00a0vivo","volume":"103","author":"Haas","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib21","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.tins.2009.07.003","article-title":"Glutamate synapse in developing brain: an integrative perspective beyond the silent state","volume":"32","author":"Hanse","year":"2009","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib22","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.neuron.2010.01.024","article-title":"Critical period plasticity is disrupted in the barrel cortex of FMR1 knockout mice","volume":"65","author":"Harlow","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib23","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.tins.2009.11.003","article-title":"mTOR signalling: at the crossroads of plasticity, memory and disease","volume":"33","author":"Hoeffer","year":"2010","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib24","doi-asserted-by":"crossref","first-page":"5324","DOI":"10.1523\/JNEUROSCI.16-17-05324.1996","article-title":"Bidirectional regulation of protein kinase M in the maintenance of long-term potentiation and long-term depression","volume":"16","author":"Hrabetova","year":"1996","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib25","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/nn1218","article-title":"Neural activity and the dynamics of central nervous system development","volume":"7","author":"Hua","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib26","doi-asserted-by":"crossref","first-page":"7746","DOI":"10.1073\/pnas.122205699","article-title":"Altered synaptic plasticity in a mouse model of fragile X mental retardation","volume":"99","author":"Huber","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"7","key":"10.1016\/j.neuropharm.2012.03.010_bib27","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.neuropharm.2004.08.007","article-title":"JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist","volume":"47","author":"Lavreysen","year":"2004","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib28","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/nn829","article-title":"Protein kinase Mzeta is necessary and sufficient for LTP maintenance","volume":"5","author":"Ling","year":"2002","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib29","doi-asserted-by":"crossref","first-page":"12229","DOI":"10.1523\/JNEUROSCI.2842-09.2009","article-title":"PKMzeta restricts dendritic arbor growth by filopodial and branch stabilization within the intact and awake developing brain","volume":"29","author":"Liu","year":"2009","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib30","doi-asserted-by":"crossref","first-page":"e10400","DOI":"10.1371\/journal.pone.0010400","article-title":"PKMzeta inhibition reverses learning-induced increases in hippocampal synaptic strength and memory during trace eyeblink conditioning","volume":"5","author":"Madro\u00f1al","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib31","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.neuron.2004.09.012","article-title":"LTP and LTD: an embarrassment of riches","volume":"44","author":"Malenka","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib32","doi-asserted-by":"crossref","first-page":"7821","DOI":"10.1523\/JNEUROSCI.1697-04.2004","article-title":"Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression","volume":"24","author":"Massey","year":"2004","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib33","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1073\/pnas.83.6.1931","article-title":"Excitatory amino acid recognition sites coupled with inositol phospholipid metabolism: developmental changes and interaction with alpha 1-adrenoceptors","volume":"83","author":"Nicoletti","year":"1986","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2010.10.022","article-title":"Metabotropic glutamate receptors: from the workbench to the bedside","author":"Nicoletti","year":"2011","journal-title":"Neuropharmacology"},{"issue":"8","key":"10.1016\/j.neuropharm.2012.03.010_bib35","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1523\/JNEUROSCI.16-08-02444.1996","article-title":"Protein synthesis-dependent formation of protein kinase Mzeta in long-term potentiation","volume":"16","author":"Osten","year":"1996","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib36","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.neuron.2008.05.023","article-title":"Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc\/Arg3.1 essential for mGluR-LTD","volume":"59","author":"Park","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib37","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1126\/science.1128657","article-title":"Storage of spatial information by the maintenance mechanism of LTP","volume":"313","author":"Pastalkova","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib38","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0026-895X(25)08728-0","article-title":"Changes in the carboxyl-terminal domain of metabotropic glutamate receptor 1 by alternative splicing generate receptors with differing agonist-independent activity","volume":"49","author":"Pr\u00e9zeau","year":"1996","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib39","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1002\/(SICI)1097-4695(19990215)38:3<357::AID-NEU5>3.0.CO;2-#","article-title":"NMDA receptor activity stabilizes presynaptic retinotectal axons and postsynaptic optic tectal cell dendrites in\u00a0vivo","volume":"38","author":"Rajan","year":"1999","journal-title":"J.\u00a0Neurobiol."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib40","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/nrn2949","article-title":"How does PKM\u03b6 maintain long-term memory?","volume":"12","author":"Sacktor","year":"2011","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib41","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1073\/pnas.1016849108","article-title":"Metaplasticity governs compartmentalization of synaptic tagging and capture through brain-derived neurotrophic factor (BDNF) and protein kinase M{zeta} (PKM{zeta})","volume":"108","author":"Sajikumar","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib42","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1523\/JNEUROSCI.5132-04.2005","article-title":"Persistent phosphorylation by protein kinase Mzeta maintains late-phase long-term potentiation","volume":"25","author":"Serrano","year":"2005","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib43","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1042\/BST0380507","article-title":"The developmental roles of FMRP","volume":"38","author":"Till","year":"2010","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1126\/scisignal.2000451","article-title":"Pin1 and PKMz Sequentially control dendritic protein synthesis","volume":"3","author":"Westmark","year":"2010","journal-title":"Sci. Signal."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib45","doi-asserted-by":"crossref","first-page":"2454","DOI":"10.1073\/pnas.0610875104","article-title":"Absence of metabotropic glutamate receptor-mediated plasticity in the neocortex of fragile X mice","volume":"104","author":"Wilson","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuropharm.2012.03.010_bib46","doi-asserted-by":"crossref","first-page":"7820","DOI":"10.1523\/JNEUROSCI.0223-08.2008","article-title":"PKM zeta maintains late long-term potentiation by N-ethylmaleimide-sensitive factor\/GluR2-dependent trafficking of postsynaptic AMPA receptors","volume":"28","author":"Yao","year":"2008","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2012.03.010_bib47","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S0306-4522(98)00764-7","article-title":"Input-and layer-dependent synaptic plasticity in the rat perirhinal cortex in\u00a0vitro","volume":"92","author":"Ziakopoulos","year":"1999","journal-title":"Neuroscience"}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390812001086?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390812001086?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T06:42:18Z","timestamp":1758436938000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390812001086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":47,"alternative-id":["S0028390812001086"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2012.03.010","relation":{},"ISSN":["0028-3908"],"issn-type":[{"type":"print","value":"0028-3908"}],"subject":[],"published":{"date-parts":[[2013,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Constitutively active group I mGlu receptors and PKMzeta regulate synaptic transmission in developing perirhinal cortex","name":"articletitle","label":"Article Title"},{"value":"Neuropharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuropharm.2012.03.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}