{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:21:47Z","timestamp":1791260507361,"version":"4.1.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"crossref","award":["02\/CE\/B124"],"award-info":[{"award-number":["02\/CE\/B124"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"crossref","award":["07\/CE\/B1368"],"award-info":[{"award-number":["07\/CE\/B1368"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1016\/j.neuropharm.2012.05.006","type":"journal-article","created":{"date-parts":[[2012,5,17]],"date-time":"2012-05-17T22:02:42Z","timestamp":1337292162000},"page":"236-241","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["Impact of early-life stress, on group III mGlu receptor levels in the rat hippocampus: Effects of ketamine, electroconvulsive shock therapy and fluoxetine treatment"],"prefix":"10.1016","volume":"66","author":[{"given":"Richard M.","family":"O' Connor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo M.","family":"Pusceddu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy G.","family":"Dinan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John F.","family":"Cryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2012.05.006_bib1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/nature10130","article-title":"NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses","volume":"475","author":"Autry","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib2","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0006-3223(99)00230-9","article-title":"Antidepressant effects of ketamine in depressed patients","volume":"47","author":"Berman","year":"2000","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib3","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1017\/CBO9780511760334.017","article-title":"Current advances and trends in the treatment of depression","volume":"15","author":"Blier","year":"1994","journal-title":"Trends Pharmacol. Sci."},{"issue":"Suppl. 14","key":"10.1016\/j.neuropharm.2012.05.006_bib4","first-page":"4","article-title":"Antidepressant efficacy and tolerability of the selective norepinephrine reuptake inhibitor reboxetine: a review","volume":"59","author":"Burrows","year":"1998","journal-title":"J.\u00a0Clin. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib5","first-page":"27","article-title":"ECS-Induced mossy fiber sprouting and BDNF expression are attenuated by ketamine pretreatment","volume":"17","author":"Chen","year":"2001","journal-title":"J.\u00a0ECT"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib6","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/0006-3223(95)00663-X","article-title":"Rearing experience and biogenic amine activity in infant rhesus monkeys","volume":"40","author":"Clarke","year":"1996","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib7","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1146\/annurev.pharmtox.37.1.205","article-title":"Pharmacology and functions of metabotropic glutamate receptors","volume":"37","author":"Conn","year":"1997","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib8","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0896-6273(03)00195-8","article-title":"Finding the intracellular signaling pathways affected by mood disorder treatments","volume":"38","author":"Coyle","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib9","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0010-440X(61)80007-2","article-title":"The psychotropic effects of cycloserine: a new use for an antibiotic","volume":"2","author":"Crane","year":"1961","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib10","series-title":"Handbook of Anxiety and Fear","article-title":"The glutamatergic system as a potential therapeutic target for the treatment of anxiety disorders","author":"Cryan","year":"2007"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib11","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1016\/S0022-3565(24)39013-5","article-title":"Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) receptors","volume":"295","author":"Cryan","year":"2000","journal-title":"J.\u00a0Pharmacol. Exp. Ther."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib12","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1126\/science.1194313","article-title":"Neuroscience. A glutamate pathway to faster-acting antidepressants?","volume":"329","author":"Cryan","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib13","doi-asserted-by":"crossref","first-page":"8186","DOI":"10.1073\/pnas.0401080101","article-title":"Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors","volume":"101","author":"Cryan","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib14","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1001\/archgenpsychiatry.2010.90","article-title":"A\u00a0randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression","volume":"67","author":"Diazgranados","year":"2010","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib15","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/00004850-199300840-00003","article-title":"A\u00a0rational approach to the non-responding depressed patient","volume":"8","author":"Dinan","year":"1993","journal-title":"Int. Clin. Psychopharmacol."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib16","first-page":"181","article-title":"Molecular and cellular actions of chronic electroconvulsive seizures","volume":"14","author":"Duman","year":"1998","journal-title":"J.\u00a0ECT"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib17","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.neuropharm.2011.08.044","article-title":"Signaling pathways underlying the rapid antidepressant actions of ketamine","volume":"62","author":"Duman","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib18","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0006-3223(03)00231-2","article-title":"Diagnosis and definition of treatment-resistant depression","volume":"53","author":"Fava","year":"2003","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib19","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/s00441-006-0266-5","article-title":"Metabotropic glutamate receptors","volume":"326","author":"Ferraguti","year":"2006","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib20","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0169-328X(94)90259-3","article-title":"Differential expression of metabotropic glutamate receptors in the hippocampus and entorhinal cortex of the rat. Brain research","volume":"21","author":"Fotuhi","year":"1994","journal-title":"Mol. Brain Res."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib21","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1053\/j.gastro.2010.03.003","article-title":"Riluzole normalizes early-life stress-induced visceral hypersensitivity in rats: role of spinal glutamate reuptake mechanisms","volume":"138","author":"Gosselin","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib22","article-title":"Antidepressant-like properties of oral riluzole and utility of incentive disengagement models of depression in mice","author":"Gourley","year":"2011","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta9090","article-title":"Clinical and cost-effectiveness of electroconvulsive therapy for depressive illness, schizophrenia, catatonia and mania: systematic reviews and economic modelling studies","volume":"9","author":"Greenhalgh","year":"2005","journal-title":"Health Technol. Assess."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib24","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1176\/appi.ajp.2011.11060835","article-title":"A\u00a0new lead from genetic studies in depressed siblings: assessing studies of chromosome 3","volume":"168","author":"Hamilton","year":"2011","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib25","article-title":"Metabotropic and ionotropic glutamate receptors as\u00a0neurobiological targets in anxiety and stress-related disorders: focus on pharmacology and preclinical translational models","author":"Harvey","year":"2011","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib26","doi-asserted-by":"crossref","first-page":"959","DOI":"10.4088\/JCP.v65n0712","article-title":"Incidence and duration of side effects and those rated as bothersome with selective serotonin reuptake inhibitor treatment for depression: patient report versus physician estimate","volume":"65","author":"Hu","year":"2004","journal-title":"J.\u00a0Clin. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib27","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s00726-006-0316-z","article-title":"Combined administration of PHCCC, a positive allosteric modulator of mGlu4 receptors and ACPT-I, mGlu III receptor agonist evokes antidepressant-like effects in rats","volume":"32","author":"Klak","year":"2007","journal-title":"Amino Acids"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib28","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1126\/science.1190287","article-title":"mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists","volume":"329","author":"Li","year":"2010","journal-title":"Science"},{"issue":"Suppl.\u00a04","key":"10.1016\/j.neuropharm.2012.05.006_bib29","first-page":"11","article-title":"Distinguishing roles for norepinephrine and serotonin in the behavioral effects of antidepressant drugs","volume":"65","author":"Lucki","year":"2004","journal-title":"J.\u00a0Clin. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib30","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.2174\/138161209788168010","article-title":"Targeting glutamatergic signaling for the development of novel therapeutics for mood disorders","volume":"15","author":"Machado-Vieira","year":"2009","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib31","doi-asserted-by":"crossref","first-page":"9104","DOI":"10.1523\/JNEUROSCI.20-24-09104.2000","article-title":"Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus","volume":"20","author":"Malberg","year":"2000","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib32","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.biopsych.2006.04.037","article-title":"Antidepressant-like effects of ceftriaxone in male C57BL\/6J mice","volume":"61","author":"Mineur","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib33","doi-asserted-by":"crossref","first-page":"10841","DOI":"10.1523\/JNEUROSCI.23-34-10841.2003","article-title":"Gene profile of electroconvulsive seizures: induction of neurotrophic and angiogenic factors","volume":"23","author":"Newton","year":"2003","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib34","doi-asserted-by":"crossref","first-page":"7539","DOI":"10.1523\/JNEUROSCI.15-11-07539.1995","article-title":"Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments","volume":"15","author":"Nibuya","year":"1995","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib35","series-title":"G\u00a0Protein-Coupled Receptors","first-page":"321","article-title":"Role of metabotropic glutamate receptors in CNS\u00a0disorders","author":"O'Connor","year":"2010"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib36","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.ejphar.2010.02.059","article-title":"Metabotropic glutamate receptor 7: at the interface of cognition and emotion","volume":"639","author":"O'Connor","year":"2010","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib37","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1111\/j.1365-2982.2007.01065.x","article-title":"Evidence of an enhanced central 5HT response in irritable bowel syndrome and in the rat maternal separation model","volume":"20","author":"O'Mahony","year":"2008","journal-title":"Neurogastroenterol. Motil."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib38","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.biopsych.2008.06.026","article-title":"Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses","volume":"65","author":"O'Mahony","year":"2009","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib39","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.neulet.2010.07.018","article-title":"Comparison of hippocampal metabotropic glutamate receptor 7 (mGlu7) mRNA levels in two animal models of depression","volume":"482","author":"O'Mahony","year":"2010","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib40","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.neuropharm.2003.09.006","article-title":"Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats","volume":"46","author":"Palucha","year":"2004","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib41","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s00213-007-0856-2","article-title":"Activation of the mGlu7 receptor elicits antidepressant-like effects in mice","volume":"194","author":"Palucha","year":"2007","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib42","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1196\/annals.1300.016","article-title":"Glutamate and depression: clinical and preclinical studies","volume":"1003","author":"Paul","year":"2003","journal-title":"Ann. N. Y Acad. Sci."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib43","first-page":"22","article-title":"The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission. Nature reviews","volume":"13","author":"Popoli","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib44","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/nrd1346","article-title":"Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia","volume":"3","author":"Roth","year":"2004","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib45","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1001\/archpsyc.61.7.705","article-title":"Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression","volume":"61","author":"Sanacora","year":"2004","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib60","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1152\/jn.1997.77.2.527","article-title":"Presynaptic modulation by metabotropic glutamate receptors of excitatory and inhibitory synaptic inputs to hypothalamic magnocellular neurons","volume":"77","author":"Schrader","year":"1997","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib46","doi-asserted-by":"crossref","first-page":"11352","DOI":"10.1073\/pnas.0710858105","article-title":"Electroconvulsive seizure and VEGF increase the proliferation of neural stem-like cells in rat hippocampus","volume":"105","author":"Segi-Nishida","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib47","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/mp.2009.125","article-title":"Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies","volume":"16","author":"Shyn","year":"2011","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib48","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.biopsych.2005.10.013","article-title":"TNFalpha signaling in depression and anxiety: behavioral consequences of individual receptor targeting","volume":"59","author":"Simen","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib49","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/nrd1630","article-title":"Metabotropic glutamate receptors as novel targets for anxiety and stress disorders","volume":"4","author":"Swanson","year":"2005","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib50","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1080\/07853890701483270","article-title":"Intracellular signaling pathways pave roads to recovery for mood disorders","volume":"39","author":"Tanis","year":"2007","journal-title":"Ann. Med."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib51","first-page":"707","article-title":"Anxiolytic- and antidepressant-like effects of group III metabotropic glutamate agonist (1S, 3R, 4S)-1-aminocyclopentane-1,3,4-tricarboxylic acid (ACPT-I) in rats","volume":"54","author":"Tatarczynska","year":"2002","journal-title":"Pol J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib52","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.biopsych.2010.06.030","article-title":"Genome-wide association scan of trait depression","volume":"68","author":"Terracciano","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib53","doi-asserted-by":"crossref","first-page":"15007","DOI":"10.1523\/JNEUROSCI.1436-10.2010","article-title":"Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents","volume":"30","author":"Uchida","year":"2010","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib54","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/j.1399-5618.2009.00752.x","article-title":"Vesicular glutamate transporter mRNA expression in the medial temporal lobe in major depressive disorder, bipolar disorder, and schizophrenia","volume":"11","author":"Uezato","year":"2009","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib55","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1002\/syn.10200","article-title":"Fluoxetine depresses glutamate exocytosis in the rat cerebrocortical nerve terminals (synaptosomes) via inhibition of P\/Q-type Ca2+ channels","volume":"48","author":"Wang","year":"2003","journal-title":"Synapse"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib56","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.brainres.2007.10.006","article-title":"Citalopram influences mGlu7, but not mGlu4 receptors' expression in the rat brain hippocampus and cortex","volume":"1184","author":"Wieronska","year":"2007","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib57","first-page":"844","article-title":"Olfactory bulbectomy and amitriptyline treatment influences mGlu receptors expression in the mouse brain hippocampus","volume":"60","author":"Wieronska","year":"2008","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.neuropharm.2012.05.006_bib58","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nature05911","article-title":"Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls","volume":"447","author":"WTCCC","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2012.05.006_bib59","doi-asserted-by":"crossref","first-page":"293","DOI":"10.3109\/10673229.2010.511059","article-title":"Glutamatergic modulators: the future of treating mood disorders?","volume":"18","author":"Zarate","year":"2010","journal-title":"Harv. Rev. Psychiatry"}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390812001918?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390812001918?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T07:05:56Z","timestamp":1743145556000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390812001918"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":60,"alternative-id":["S0028390812001918"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2012.05.006","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]}}}