{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T19:52:14Z","timestamp":1779220334575,"version":"3.51.4"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":45,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Wellcome Trust Project","award":["082640"],"award-info":[{"award-number":["082640"]}]},{"name":"NC3Rs","award":["G0900775"],"award-info":[{"award-number":["G0900775"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1016\/j.neuropharm.2012.11.004","type":"journal-article","created":{"date-parts":[[2012,11,20]],"date-time":"2012-11-20T12:31:53Z","timestamp":1353414713000},"page":"105-114","source":"Crossref","is-referenced-by-count":116,"special_numbering":"C","title":["Seizure control by ketogenic diet-associated medium chain fatty acids"],"prefix":"10.1016","volume":"69","author":[{"given":"Pishan","family":"Chang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Terbach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"Plant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip E.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew C.","family":"Walker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin S.B.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2012.11.004_bib1","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0920-1211(98)00030-8","article-title":"Effects of new valproate derivatives on epileptiform discharges induced by pentylenetetrazole or low Mg2+ in rat entorhinal cortex\u2013hippocampus slices","volume":"32","author":"Armand","year":"1998","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib2","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1351\/pac200173040685","article-title":"Lexicon of lipid nutrition (IUPAC technical report)","volume":"73","author":"Beare-Rogers","year":"2001","journal-title":"Pure Appl. Chem."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib3","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0304-4211(76)90068-7","article-title":"The occurrence and function of short chain length fatty acids in plants","volume":"6","author":"Berrie","year":"1975","journal-title":"Plant Sci. Lett."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib4","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/nrd2997","article-title":"Key factors in the discovery and development of new antiepileptic drugs","volume":"9","author":"Bialer","year":"2010","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib5","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1021\/tx950216s","article-title":"Further branching of valproate-related carboxylic acids reduces the teratogenic activity, but not the anticonvulsant effect","volume":"9","author":"Bojic","year":"1996","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib6","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0309-1740(92)90024-X","article-title":"Distribution of volatile branched-chain fatty acids in various lamb tissues","volume":"31","author":"Brennand","year":"1992","journal-title":"Meat Sci."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib7","doi-asserted-by":"crossref","first-page":"6813","DOI":"10.1523\/JNEUROSCI.5320-05.2006","article-title":"Chronic valproic acid treatment triggers increased neuropeptide y expression and signaling in rat nucleus reticularis thalami","volume":"26","author":"Brill","year":"2006","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib8","doi-asserted-by":"crossref","first-page":"9519","DOI":"10.1523\/JNEUROSCI.19-21-09519.1999","article-title":"Highly specific neuron loss preserves lateral inhibitory circuits in the dentate gyrus of kainate-induced epileptic rats","volume":"19","author":"Buckmaster","year":"1999","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib9","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1111\/j.1528-1167.2009.02412.x","article-title":"Inhibition of long-term potentiation by valproic acid through modulation of cyclic AMP","volume":"51","author":"Chang","year":"2010","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib10","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1242\/dmm.008029","article-title":"The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium","volume":"5","author":"Chang","year":"2011","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib11","first-page":"63","article-title":"Effects of anticonvulsant drugs on brain amino acid metabolism","volume":"124","author":"Chapman","year":"1983","journal-title":"Prog. Clin. Biol. Res."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib12","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/j.1528-1157.1980.tb04315.x","article-title":"Epilepsy and neuron loss in the hippocampus","volume":"21","author":"Dam","year":"1980","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib13","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/0006-8993(89)90234-5","article-title":"Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy","volume":"495","author":"de Lanerolle","year":"1989","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib14","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1021\/tx0502241","article-title":"Teratogenic effects mediated by inhibition of histone deacetylases: evidence from quantitative structure activity relationships of 20 valproic acid derivatives","volume":"19","author":"Eikel","year":"2006","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib15","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1242\/dmm.008391","article-title":"Conserved valproic acid-induced lipid droplet formation in Dictyostelium and human hepatocytes (huh7) identifies structurally active compounds","volume":"5","author":"Elphick","year":"2011","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib16","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1111\/j.0013-9580.2004.26404.x","article-title":"Synergism between topiramate and budipine in refractory status epilepticus in the rat","volume":"45","author":"Fisher","year":"2004","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib17","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.eplepsyres.2005.10.003","article-title":"The ketogenic diet: from molecular mechanisms to clinical effects","volume":"68","author":"Freeman","year":"2006","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib18","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1002\/jat.1420","article-title":"In\u00a0vitro assay for drug-induced hepatosteatosis using rat primary hepatocytes, a fluorescent lipid analog and gene expression analysis","volume":"29","author":"Fujimura","year":"2009","journal-title":"J.\u00a0Appl. Toxicol."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib19","first-page":"912","article-title":"Effects of medium chain length triglyceride (MCT) on serum lipids and lipoproteins in familial hyperchylomicronemia (dietary fat-induced lipemia) and dietary carbohydrate-accentuated lipemia","volume":"66","author":"Furman","year":"1965","journal-title":"J.\u00a0Lab. Clin. Med."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib20","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1111\/j.1528-1167.2011.03391.x","article-title":"Identification of new epilepsy treatments: issues in preclinical methodology","volume":"53","author":"Galanopoulou","year":"2012","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib21","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1097\/00008877-200609000-00009","article-title":"Neuroprotective and disease-modifying effects of the ketogenic diet","volume":"17","author":"Gasior","year":"2006","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib22","doi-asserted-by":"crossref","first-page":"6969","DOI":"10.1093\/emboj\/20.24.6969","article-title":"Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells","volume":"20","author":"Gottlicher","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib23","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1158\/0008-5472.CAN-03-0799","article-title":"Histone deacetylase is a target of valproic acid-mediated cellular differentiation","volume":"64","author":"Gurvich","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib24","doi-asserted-by":"crossref","first-page":"677","DOI":"10.3168\/jds.S0022-0302(93)77391-9","article-title":"Release of volatile branched-chain and other fatty acids from ruminant milk fats by various lipases","volume":"76","author":"Ha","year":"1993","journal-title":"J.\u00a0Dairy Sci."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib25","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1093\/clinchem\/28.4.642","article-title":"Monitoring octanoic and decanoic acids in plasma from children with intractable epilepsy treated with medium-chain triglyceride diet","volume":"28","author":"Haidukewych","year":"1982","journal-title":"Clin. Chem."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib26","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1002\/1531-8249(20010201)49:2<260::AID-ANA49>3.0.CO;2-Y","article-title":"Propofol in subanesthetic doses terminates status epilepticus in a rodent model","volume":"49","author":"Holtkamp","year":"2001","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib27","doi-asserted-by":"crossref","first-page":"29","DOI":"10.4103\/0028-3886.60392","article-title":"Conditional downregulation of brain-derived neurotrophic factor and tyrosine kinase receptor B blocks epileptogenesis in the human temporal lobe epilepsy hippocampus","volume":"58","author":"Hou","year":"2010","journal-title":"Neurol. India"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib28","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1212\/WNL.21.11.1097","article-title":"Medium-chain triglycerides as a therapy for intractable childhood epilepsy","volume":"21","author":"Huttenlocher","year":"1971","journal-title":"Neurology"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib29","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1056\/NEJMoa0907328","article-title":"Valproic acid monotherapy in pregnancy and major congenital malformations","volume":"362","author":"Jentink","year":"2010","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib30","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/0028-3908(83)90134-X","article-title":"The effects of analogues of valproic acid on seizures induced by pentylenetetrazol and GABA content in brain of mice","volume":"22","author":"Keane","year":"1983","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib31","article-title":"Major malformations with valproic acid","volume":"52","author":"Koren","year":"2006","journal-title":"Can. Fam. Physician"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib32","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1177\/0883073809337162","article-title":"Ketogenic diets: an update for child neurologists","volume":"24","author":"Kossoff","year":"2009","journal-title":"J.\u00a0Child. Neurol."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib33","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.cnr.2004.09.013","article-title":"Valproic acid: how it works. Or not","volume":"4","author":"Lagace","year":"2005","journal-title":"Clin. Neurosci. Res."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib34","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1213\/00000539-199803000-00040","article-title":"Propofol sedation produces dose-dependent suppression of lidocaine-induced seizures in rats","volume":"86","author":"Lee","year":"1998","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib35","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1111\/j.1528-1157.2000.tb00115.x","article-title":"Dietary fat, ketosis, and seizure resistance in rats on the ketogenic diet","volume":"41","author":"Likhodii","year":"2000","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib36","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1172\/JCI105438","article-title":"Medium and long chain fat absorption in patients with cirrhosis","volume":"45","author":"Linscheer","year":"1966","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib37","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/j.1528-1157.1994.tb02939.x","article-title":"Pharmacokinetics and pharmacodynamics of valproate analogues in rats. IV. Anticonvulsant action and neurotoxicity of octanoic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid","volume":"35","author":"Liu","year":"1994","journal-title":"Epilepsia"},{"issue":"Suppl. 8","key":"10.1016\/j.neuropharm.2012.11.004_bib38","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1528-1167.2008.01830.x","article-title":"Medium-chain triglyceride (MCT) ketogenic therapy","volume":"49","author":"Liu","year":"2008","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib39","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/0028-3908(85)90028-0","article-title":"Pharmacological evaluation of various metabolites and analogues of valproic acid. Anticonvulsant and toxic potencies in mice","volume":"24","author":"Loscher","year":"1985","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib40","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/S1359-6446(04)03297-0","article-title":"Improving the decision-making process in structural modification of drug candidates: reducing toxicity","volume":"9","author":"Nassar","year":"2004","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib41","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1111\/j.1528-1167.2008.01870.x","article-title":"A\u00a0randomized trial of classical and medium-chain triglyceride ketogenic diets in the treatment of childhood epilepsy","volume":"50","author":"Neal","year":"2009","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib42","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1079\/BJN19790015","article-title":"Artificial rearing of pigs. 7. Medium chain triglycerides as a dietary source of energy and their effect on live-weight gain, feed:gain ratio, carcass composition and blood lipids","volume":"41","author":"Newport","year":"1979","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib43","doi-asserted-by":"crossref","first-page":"3398","DOI":"10.1021\/jm00017a024","article-title":"Structure\u2013activity relationships of unsaturated analogues of valproic acid","volume":"38","author":"Palaty","year":"1995","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib44","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"1998"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib45","doi-asserted-by":"crossref","first-page":"36734","DOI":"10.1074\/jbc.M101287200","article-title":"Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen","volume":"276","author":"Phiel","year":"2001","journal-title":"J.\u00a0Biol. Chem."},{"issue":"Suppl. 8","key":"10.1016\/j.neuropharm.2012.11.004_bib46","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1528-1167.2008.01857.x","article-title":"The ketogenic diet in a pill: is this possible?","volume":"49","author":"Rho","year":"2008","journal-title":"Epilepsia"},{"issue":"3","key":"10.1016\/j.neuropharm.2012.11.004_bib47","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.eplepsyres.2011.05.021","article-title":"The ketogenic diet: what has science taught us?","volume":"100","author":"Rho","year":"2012","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib48","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1749-6632.2000.tb06734.x","article-title":"Epileptogenesis in the parahippocampal region. Parallels with the dentate gyrus","volume":"911","author":"Scharfman","year":"2000","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib49","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1136\/adc.61.12.1173","article-title":"Role of octanoic and decanoic acids in the control of seizures","volume":"61","author":"Sills","year":"1986","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib50","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1136\/adc.61.12.1168","article-title":"The medium chain triglyceride diet and intractable epilepsy","volume":"61","author":"Sills","year":"1986","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib51","doi-asserted-by":"crossref","DOI":"10.1007\/s10545-008-0841-x","article-title":"Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review","author":"Silva","year":"2008","journal-title":"J.\u00a0Inherit. Metab. Dis."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib52","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1093\/jn\/132.3.329","article-title":"Physiological effects of medium-chain triglycerides: potential agents in the prevention of obesity","volume":"132","author":"St-Onge","year":"2002","journal-title":"J.\u00a0Nutr."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib53","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1007\/BF01962700","article-title":"Valproate hepatotoxicity syndrome: hypotheses of pathogenesis","volume":"14","author":"Stephens","year":"1992","journal-title":"Pharm. Weekbl. Sci."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib54","doi-asserted-by":"crossref","first-page":"3113","DOI":"10.1021\/jf960049h","article-title":"Free fatty acids composition of the adipose tissue of intact and castrated lambs slaughtered at 12 and 30 weeks of age","volume":"44","author":"Sutherland","year":"1994","journal-title":"J.\u00a0Agric. Food Chem."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib55","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1006\/exnr.1999.7298","article-title":"The MCT ketogenic diet: effects on animal seizure models","volume":"161","author":"Thavendiranathan","year":"2000","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib56","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1001\/archneur.55.11.1433","article-title":"A\u00a0multicenter study of the efficacy of the ketogenic diet","volume":"55","author":"Vining","year":"1998","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib57","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1528-1157.1999.tb00718.x","article-title":"Halothane as a neuroprotectant during constant stimulation of the perforant path","volume":"40","author":"Walker","year":"1999","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib58","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1016\/S0140-6736(98)04512-7","article-title":"Age-specific incidence and prevalence rates of treated epilepsy in an unselected population of 2,052,922 and age-specific fertility rates of women with epilepsy","volume":"352","author":"Wallace","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib59","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.molmed.2006.07.003","article-title":"Towards a molecular understanding of human diseases using Dictyostelium discoideum","volume":"12","author":"Williams","year":"2006","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.neuropharm.2012.11.004_bib60","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1038\/417292a","article-title":"A\u00a0common mechanism of action for three mood-stabilizing drugs","volume":"417","author":"Williams","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib61","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1016\/j.neuropharm.2011.12.015","article-title":"Anticonvulsant profile of caprylic acid, a main constituent of the medium-chain triglyceride (MCT) ketogenic diet, in mice","volume":"62","author":"Wlaz","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2012.11.004_bib62","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1128\/EC.00104-06","article-title":"Attenuation of phospholipid signaling provides a novel mechanism for the action of valproic acid","volume":"6","author":"Xu","year":"2007","journal-title":"Eukaryot. Cell"}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390812005382?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390812005382?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T06:34:29Z","timestamp":1594881269000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390812005382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":62,"alternative-id":["S0028390812005382"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2012.11.004","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2013,6]]}}}