{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T09:09:21Z","timestamp":1792660161953,"version":"4.5.0"},"reference-count":101,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100011602","name":"LabEx ASLAN","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016784","name":"Equipex","doi-asserted-by":"publisher","award":["ANR-10-EQPX-08"],"award-info":[{"award-number":["ANR-10-EQPX-08"]}],"id":[{"id":"10.13039\/100016784","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.neuropharm.2013.07.014","type":"journal-article","created":{"date-parts":[[2013,8,2]],"date-time":"2013-08-02T03:01:42Z","timestamp":1375412502000},"page":"437-449","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":77,"special_numbering":"PB","title":["Psychobiology of cocaine addiction: Contribution of a multi-symptomatic animal model of loss of control"],"prefix":"10.1016","volume":"76","author":[{"given":"V\u00e9ronique","family":"Deroche-Gamonet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier Vincenzo","family":"Piazza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2013.07.014_bib1","first-page":"244","article-title":"Comparative epidemiology of dependence on tobacco, alcohol, controlled substances, and inhalants: basic findings from the National comorbidity Survey","volume":"2","author":"Anthony","year":"1994"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib2","series-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"APA","year":"2000"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib3","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/BF01573620","article-title":"Causes and types of narcotic addiction: a psychosocial view","volume":"35","author":"Ausubel","year":"1961","journal-title":"Psychiatr. Q."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1521\/pedi.1998.12.1.1","article-title":"Personality disorder and dimension differences between type A and type B substance abusers","volume":"12","author":"Ball","year":"1998","journal-title":"J.\u00a0Pers. Disord."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib5","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/nprot.2008.41","article-title":"The application of the 5-choice serial reaction time task for the assessment of visual attentional processes and impulse control in rats","volume":"3","author":"Bari","year":"2008","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib6","series-title":"Contextual and Other Factors Related to Workplace-based Substance Abuse Prevention and Early Intervention for Adolescents and Young Adults","author":"Batts","year":"2005"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib7","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1038\/nn1584","article-title":"Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective","volume":"8","author":"Bechara","year":"2005","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib8","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.biopsych.2008.05.031","article-title":"Pattern of intake and drug craving predict the development of cocaine addiction-like behavior in rats","volume":"65","author":"Belin","year":"2009","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib9","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/npp.2010.188","article-title":"High-novelty-preference rats are predisposed to compulsive cocaine self-administration","volume":"36","author":"Belin","year":"2011","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib10","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1126\/science.1158136","article-title":"High impulsivity predicts the switch to compulsive cocaine-taking","volume":"320","author":"Belin","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib11","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.neubiorev.2009.05.009","article-title":"The HR\/LR model: further evidence as an animal model of sensation seeking","volume":"33","author":"Blanchard","year":"2009","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib12","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1037\/1064-1297.13.4.311","article-title":"Differences in impulsivity and risk-taking propensity between primary users of crack cocaine and primary users of heroin in a residential substance-use program","volume":"13","author":"Bornovalova","year":"2005","journal-title":"Exp. Clin. Psychopharmacol."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib13","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.neuron.2010.06.004","article-title":"AMPA receptor synaptic plasticity induced by psychostimulants: the past, present, and therapeutic future","volume":"67","author":"Bowers","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib14","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1001\/jama.1985.03360010087032","article-title":"Toxicity associated with long-term intravenous heroin and cocaine self-administration in the rat","volume":"254","author":"Bozarth","year":"1985","journal-title":"JAMA"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib15","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1037\/1064-1297.13.4.367","article-title":"Novelty seeking and drug use: contribution of an animal model","volume":"13","author":"Cain","year":"2005","journal-title":"Exp. Clin. Psychopharmacol."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib16","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.neuron.2008.05.024","article-title":"Cocaine but not natural reward self-administration nor passive cocaine infusion produces persistent LTP in the VTA","volume":"59","author":"Chen","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib17","first-page":"25","article-title":"Classically conditioned responses in opioid and cocaine dependence: a role in relapse?","volume":"84","author":"Childress","year":"1988","journal-title":"NIDA Res. Monogr."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib18","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0899-3289(94)90491-X","article-title":"Personality, social environment, and past behavior as predictors of late adolescent alcohol use","volume":"6","author":"Clapper","year":"1994","journal-title":"J.\u00a0Subst. Abuse"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib19","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1037\/1064-1297.11.1.18","article-title":"Impulsivity and rapid discounting of delayed hypothetical rewards in cocaine-dependent individuals","volume":"11","author":"Coffey","year":"2003","journal-title":"Exp. Clin. Psychopharmacol."},{"issue":"1\u20132","key":"10.1016\/j.neuropharm.2013.07.014_bib20","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.drugalcdep.2013.02.036","article-title":"Crosswalk between DSM-IV dependence and DSM-5 substance use disorders for opioids, cannabis, cocaine and alcohol","volume":"132","author":"Compton","year":"2013","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib21","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0376-8716(01)00168-5","article-title":"Personality, drug of choice, and comorbid psychopathology among substance abusers","volume":"65","author":"Conway","year":"2002","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib22","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/j.1521-0391.2010.00097.x","article-title":"Decision-making deficits linked to real-life social dysfunction in crack cocaine-dependent individuals","volume":"20","author":"Cunha","year":"2011","journal-title":"Am. J. Addict"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib23","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0740-5472(01)00192-1","article-title":"Cocaine dependence: a disease of the brain\u2019s reward centers","volume":"21","author":"Dackis","year":"2001","journal-title":"J.\u00a0Subst. Abuse Treat"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib24","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1159\/000119305","article-title":"Novelty-seeking in rats\u2013biobehavioral characteristics and possible relationship with the sensation-seeking trait in man","volume":"34","author":"Dellu","year":"1996","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib25","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1126\/science.1099020","article-title":"Evidence for addiction-like behavior in the rat","volume":"305","author":"Deroche-Gamonet","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib26","series-title":"Encyclopedia of Behavioral Neuroscience","first-page":"422","article-title":"Transition to addiction","author":"Deroche-Gamonet","year":"2010"},{"issue":"2","key":"10.1016\/j.neuropharm.2013.07.014_bib27","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.biopsych.2012.11.016","article-title":"Distinctive personality traits and neural correlates associated with stimulant drug use versus familial risk of stimulant dependence","volume":"74","author":"Ersche","year":"2013","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib28","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.biopsych.2005.04.046","article-title":"Neural and behavioral plasticity associated with the transition from controlled to escalated cocaine use","volume":"58","author":"Ferrario","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib29","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.brainres.2008.02.081","article-title":"The rate of intravenous cocaine administration alters c-fos mRNA expression and the temporal dynamics of dopamine, but not glutamate, overflow in the striatum","volume":"1209","author":"Ferrario","year":"2008","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib30","first-page":"68","article-title":"Addiction and personality","volume":"26","author":"Franques","year":"2000","journal-title":"Encephale"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib31","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1126\/science.2011738","article-title":"Cocaine addiction: psychology and neurophysiology","volume":"251","author":"Gawin","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib32","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1081\/JA-120028493","article-title":"Substance use among high-school students: relationships with temperament, personality traits, and parental care perception","volume":"39","author":"Gerra","year":"2004","journal-title":"Subst. Use Misuse"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib33","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.euroneuro.2003.08.004","article-title":"The impact of stress on addiction","volume":"13","author":"Goeders","year":"2003","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib34","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1038\/nrn3119","article-title":"Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications","volume":"12","author":"Goldstein","year":"2011","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib35","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.psychres.2010.07.024","article-title":"Differences in self-reported decision-making styles in stimulant-dependent and opiate-dependent individuals","volume":"186","author":"Gorodetzky","year":"2011","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib36","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/0376-8716(78)90005-4","article-title":"Drug dependence, crime and personality among female addicts","volume":"3","author":"Gossop","year":"1978","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib37","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.biopsych.2009.08.026","article-title":"Functional and dysfunctional synaptic plasticity in prefrontal cortex: roles in psychiatric disorders","volume":"67","author":"Goto","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib38","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1207\/s15327752jpa6102_2","article-title":"Personality variables in cocaine- and marijuana-dependent patients","volume":"61","author":"Greene","year":"1993","journal-title":"J.\u00a0Pers Assess."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib39","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S0306-4603(99)00043-X","article-title":"Individual differences among cocaine users","volume":"25","author":"Gunnarsd\u00f3ttir","year":"2000","journal-title":"Addict Behav."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib40","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1369-1600.2008.00121.x","article-title":"Self-administration of cocaine, cannabis and heroin in the human laboratory: benefits and pitfalls","volume":"14","author":"Haney","year":"2009","journal-title":"Addict Biol."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib41","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1037\/1064-1297.7.4.493","article-title":"Personality factors moderate subjective and psychophysiological responses to d-amphetamine in humans","volume":"7","author":"Hutchison","year":"1999","journal-title":"Exp. Clin. Psychopharmacol."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib42","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1146\/annurev.neuro.29.051605.113009","article-title":"Neural mechanisms of addiction: the role of reward-related learning and memory","volume":"29","author":"Hyman","year":"2006","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib43","doi-asserted-by":"crossref","first-page":"604","DOI":"10.2105\/AJPH.70.6.604","article-title":"Psychosocial correlates of marijuana use and problem drinking in a national sample of adolescents","volume":"70","author":"Jessor","year":"1980","journal-title":"Am. J. Public Health"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib44","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0091-3057(76)90174-X","article-title":"Self-administration of psychomotor stimulant drugs: the effects of unlimited access","volume":"4","author":"Johanson","year":"1976","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib45","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1126\/science.1187801","article-title":"Transition to addiction is associated with a persistent impairment in synaptic plasticity","volume":"328","author":"Kasanetz","year":"2010","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.neuropharm.2013.07.014_bib46","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1038\/mp.2012.59","article-title":"Prefrontal synaptic markers of cocaine addiction-like behavior in rats","volume":"18","author":"Kasanetz","year":"2013","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib47","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1037\/h0080151","article-title":"The epidemiology of co-occurring addictive and mental disorders: implications for prevention and service utilization","volume":"66","author":"Kessler","year":"1996","journal-title":"Am. J. Orthopsychiatry"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib48","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3109\/00952998609007391","article-title":"A\u00a0contemporary psychodynamic approach to drug abuse treatment","volume":"12","author":"Khantzian","year":"1986","journal-title":"Am. J. Drug Alcohol Abuse"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib49","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/nrd897","article-title":"Pharmacotherapy of addictions","volume":"1","author":"Kreek","year":"2002","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib50","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1038\/nn1583","article-title":"Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction","volume":"8","author":"Kreek","year":"2005","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib51","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1037\/0022-006X.54.3.289","article-title":"Relation of personality to alcohol and drug use in adolescence","volume":"54","author":"Labouvie","year":"1986","journal-title":"J.\u00a0Consult Clin. Psychol."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib52","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0163-7258(02)00200-0","article-title":"Neurobiology of relapse to alcohol in rats","volume":"94","author":"L\u00ea","year":"2002","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib53","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.brat.2008.03.010","article-title":"Anxiety sensitivity: a unique predictor of dropout among inner-city heroin and crack\/cocaine users in residential substance use treatment","volume":"46","author":"Lejuez","year":"2008","journal-title":"Behav. Res. Ther."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib54","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1126\/science.278.5335.45","article-title":"Addiction is a brain disease, and it matters","volume":"278","author":"Leshner","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib55","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1460-9568.2005.04195.x","article-title":"Sensitization of the reinforcing effects of self-administered cocaine in rats: effects of dose and intravenous injection speed","volume":"22","author":"Liu","year":"2005","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib56","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.neuron.2011.01.017","article-title":"Drug-evoked synaptic plasticity in addiction: from molecular changes to circuit remodeling","volume":"69","author":"L\u00fcscher","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib57","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1016\/j.neuropharm.2011.01.036","article-title":"Synaptic plasticity and addiction: learning mechanisms gone awry","volume":"61","author":"Mameli","year":"2011","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib58","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1038\/nn1713","article-title":"Cocaine self-administration selectively abolishes LTD in the core of the nucleus accumbens","volume":"9","author":"Martin","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib59","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/10550490500528316","article-title":"The addiction severity index at 25: origins, contributions and transitions","volume":"15","author":"McLellan","year":"2006","journal-title":"Am. J. Addict."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib60","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.biopsych.2012.08.011","article-title":"Discriminative inhibitory control of cocaine seeking involves the prelimbic prefrontal cortex","volume":"73","author":"Mihindou","year":"2013","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib61","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1523\/JNEUROSCI.2068-12.2013","article-title":"Covariance-based synaptic plasticity in an attractor network model accounts for fast adaptation in free operant learning","volume":"33","author":"Neiman","year":"2013","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib62","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/S0140-6736(07)60464-4","article-title":"Development of a rational scale to assess the harm of drugs of potential misuse","volume":"369","author":"Nutt","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib63","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1111\/j.1749-6632.1992.tb25984.x","article-title":"Classical conditioning in drug-dependent humans","volume":"654","author":"O'Brien","year":"1992","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib64","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.drugalcdep.2012.07.009","article-title":"Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorders in a largely substance dependent sample","volume":"127","author":"Peer","year":"2013","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib65","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00213-007-0805-0","article-title":"Compulsive drug seeking by rats under punishment: effects of drug taking history","volume":"194","author":"Pelloux","year":"2007","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib66","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1126\/science.2781295","article-title":"Factors that predict individual vulnerability to amphetamine self-administration","volume":"245","author":"Piazza","year":"1989","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib67","doi-asserted-by":"crossref","first-page":"4226","DOI":"10.1523\/JNEUROSCI.20-11-04226.2000","article-title":"Vertical shifts in self-administration dose-response functions predict a drug-vulnerable phenotype predisposed to addiction","volume":"20","author":"Piazza","year":"2000","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib68","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1146\/annurev.pa.36.040196.002043","article-title":"Pathophysiological basis of vulnerability to drug abuse: role of an interaction between stress, glucocorticoids, and dopaminergic neurons","volume":"36","author":"Piazza","year":"1996","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib69","doi-asserted-by":"crossref","DOI":"10.1007\/s00213-013-3224-4","article-title":"A multi-step general theory of transition to addiction","author":"Piazza","year":"2013","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib70","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-0270(95)00153-0","article-title":"Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy","volume":"66","author":"Richardson","year":"1996","journal-title":"J.\u00a0Neurosci. Methods"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib71","first-page":"625","article-title":"Characteristics of unlimited access to self-administered stimulant infusions in dogs","volume":"11","author":"Risner","year":"1976","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib72","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.tins.2010.02.002","article-title":"The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens","volume":"33","author":"Russo","year":"2010","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib73","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.tips.2004.12.007","article-title":"Why does the rapid delivery of drugs to the brain promote addiction?","volume":"26","author":"Samaha","year":"2005","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib74","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.biopsych.2004.11.040","article-title":"Rapid delivery of nicotine promotes behavioral sensitization and alters its neurobiological impact","volume":"57","author":"Samaha","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib75","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1207\/s15327752jpa6303_2","article-title":"Personality variables and self-medication in substance abuse","volume":"63","author":"Schinka","year":"1994","journal-title":"J.\u00a0Pers Assess."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib76","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00213-002-1224-x","article-title":"The reinstatement model of drug relapse: history, methodology and major findings","volume":"168","author":"Shaham","year":"2003","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib77","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1124\/pr.54.1.1","article-title":"Neurobiology of relapse to heroin and cocaine seeking: a review","volume":"54","author":"Shalev","year":"2002","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib78","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1037\/0022-006X.68.5.818","article-title":"Personality and substance use disorders: a prospective study","volume":"68","author":"Sher","year":"2000","journal-title":"J.\u00a0Consult Clin. Psychol."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib79","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/j.neuropharm.2011.05.034","article-title":"Endocannabinoid-mediated synaptic plasticity and addiction-related behavior","volume":"61","author":"Sidhpura","year":"2011","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib80","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1081\/ADA-100103118","article-title":"Comorbidity in a clinical sample of substance abusers","volume":"27","author":"Skinstad","year":"2001","journal-title":"Am. J. Drug Alcohol Abuse"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib81","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1016\/j.neubiorev.2010.11.008","article-title":"Adverse childhood experiences (ACEs), genetic polymorphisms and neurochemical correlates in experimentation with psychotropic drugs among adolescents","volume":"35","author":"Somaini","year":"2011","journal-title":"Neurosci. Biobehav Rev."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib82","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0376-8716(99)00017-4","article-title":"Individual risk factors for adolescent substance use","volume":"55","author":"Swadi","year":"1999","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib83","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1111\/j.1360-0443.2010.02902.x","article-title":"Mental disorders as risk factors for substance use, abuse and dependence: results from the 10-year follow-up of the National Comorbidity Survey","volume":"105","author":"Swendsen","year":"2010","journal-title":"Addiction"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib84","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1749-6632.2010.05894.x","article-title":"Individual vulnerability to addiction","volume":"1216","author":"Swendsen","year":"2011","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib85","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1471-244X-8-22","article-title":"Five-Factor model personality profiles of drug users","volume":"8","author":"Terracciano","year":"2008","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib86","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/bjp.2008.77","article-title":"Neuroplasticity in the mesolimbic dopamine system and cocaine addiction","volume":"154","author":"Thomas","year":"2008","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib87","series-title":"The Natural History of Alcoholism Revisited","author":"Vaillant","year":"1995"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib88","first-page":"152","volume":"vol. 20","author":"Vaillant","year":"1996"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib89","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1126\/science.1098975","article-title":"Drug seeking becomes compulsive after prolonged cocaine self-administration","volume":"305","author":"Vanderschuren","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib90","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1017\/S1355617706060486","article-title":"Executive dysfunction in substance dependent individuals during drug use and abstinence: an examination of the behavioral, cognitive and emotional correlates of addiction","volume":"12","author":"Verdejo-Garc\u00eda","year":"2006","journal-title":"J.\u00a0Int. Neuropsychol. Soc."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib91","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.neubiorev.2007.11.003","article-title":"Impulsivity as a vulnerability marker for substance-use disorders: review of findings from high-risk research, problem gamblers and genetic association studies","volume":"32","author":"Verdejo-Garc\u00eda","year":"2008","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib92","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.addbeh.2006.06.032","article-title":"Cognitive impulsivity in cocaine and heroin polysubstance abusers","volume":"32","author":"Verdejo-Garc\u00eda","year":"2007","journal-title":"Addict Behav."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib93","series-title":"Management of Substance Abuse: the Global Burden","author":"WHO","year":"2013"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib94","series-title":"ICD-10-CM","author":"WHO","year":"2013"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib95","article-title":"EMCDDA annual report 2009: cocaine and heroin maintain firm hold on Europe's drug scene","volume":"14","author":"Wiessing","year":"2009","journal-title":"Euro Surveill."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib96","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.neubiorev.2010.01.013","article-title":"AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine","volume":"35","author":"Wolf","year":"2010","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib97","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/S0149-7634(05)80142-3","article-title":"An ethopharmacological approach to the development of drug addiction","volume":"15","author":"Wolffgramm","year":"1991","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib98","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/s007020070067","article-title":"Animal models of addiction: models for therapeutic strategies?","volume":"107","author":"Wolffgramm","year":"2000","journal-title":"J.\u00a0Neural Transm."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib99","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0091-3057(91)90297-F","article-title":"Social behavior, dominance, and social deprivation of rats determine drug choice","volume":"38","author":"Wolffgramm","year":"1991","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.neuropharm.2013.07.014_bib100","series-title":"Sensation Seeking: Beyond the Optimal Level of Arousal","author":"Zuckerman","year":"1979"},{"key":"10.1016\/j.neuropharm.2013.07.014_bib101","first-page":"59","article-title":"Sensation seeking and the endogenous deficit theory of drug abuse","volume":"74","author":"Zuckerman","year":"1986","journal-title":"NIDA Res. Monogr."}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390813003316?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390813003316?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T23:54:38Z","timestamp":1762214078000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390813003316"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":101,"alternative-id":["S0028390813003316"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2013.07.014","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Psychobiology of cocaine addiction: Contribution of a multi-symptomatic animal model of loss of control","name":"articletitle","label":"Article Title"},{"value":"Neuropharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuropharm.2013.07.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}