{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T04:19:06Z","timestamp":1790223546111,"version":"4.1.0"},"reference-count":67,"publisher":"Elsevier BV","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1016\/j.neuropharm.2014.01.046","type":"journal-article","created":{"date-parts":[[2014,2,7]],"date-time":"2014-02-07T04:15:29Z","timestamp":1391746529000},"page":"153-165","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["5HT1B receptor-mediated pre-synaptic depression of excitatory inputs to the rat lateral habenula"],"prefix":"10.1016","volume":"81","author":[{"given":"Eun-Kyung","family":"Hwang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-mo","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2014.01.046_bib1","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0006-8993(77)90291-8","article-title":"Habenular and other midbrain raphe afferents demonstrated by a modified retrograde tracing technique","volume":"122","author":"Aghajanian","year":"1977","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib2","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1085\/jgp.80.5.663","article-title":"Block of squid axon K channels by internally and externally applied barium ions","volume":"80","author":"Armstrong","year":"1982","journal-title":"J.\u00a0Gen. Physiol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib3","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S0028-3908(99)00010-6","article-title":"A\u00a0review of central 5-HT receptors and their function","volume":"38","author":"Barnes","year":"1999","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib4","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0165-6147(00)88991-9","article-title":"5-HT2 receptor subtypes: a family re-united?","volume":"16","author":"Baxter","year":"1995","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib5","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1002\/cne.23080","article-title":"Individual neurons in the rat lateral habenular complex project mostly to the dopaminergic ventral tegmental area or to the serotonergic raphe nuclei","volume":"520","author":"Bernard","year":"2012","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib6","doi-asserted-by":"crossref","first-page":"6508","DOI":"10.1523\/JNEUROSCI.0678-08.2008","article-title":"Serotonin evokes endocannabinoid release and retrogradely suppresses excitatory synapses","volume":"28","author":"Best","year":"2008","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib7","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0306-4522(94)90164-3","article-title":"The mouse 5-hydroxytryptamine1B receptor is localized predominantly on axon terminals","volume":"58","author":"Boschert","year":"1994","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib8","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0301-0082(03)00053-4","article-title":"Presence and functional significance of presynaptic ryanodine receptors","volume":"69","author":"Bouchard","year":"2003","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib9","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1523\/JNEUROSCI.14-01-00310.1994","article-title":"Increased transmitter release at excitatory synapses produced by direct activation of adenylate cyclase in rat hippocampal slices","volume":"14","author":"Chavez-Noriega","year":"1994","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib10","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1749-6632.1999.tb11293.x","article-title":"Molecular diversity of K+ channels","volume":"868","author":"Coetzee","year":"1999","journal-title":"Ann. N Y Acad. Sci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib11","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1152\/jn.00459.2001","article-title":"D2 receptors inhibit the secretory process downstream from calcium influx in dopaminergic neurons: implication of K+ channels","volume":"87","author":"Congar","year":"2002","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00633189","article-title":"Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites","volume":"332","author":"Engel","year":"1986","journal-title":"Naunyn Schmiedeb. Arch. Pharmacol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib13","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0361-9230(96)00170-0","article-title":"Lateral habenular influence on dorsal raphe neurons","volume":"41","author":"Ferraro","year":"1996","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib14","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0143416002001999","article-title":"Calcium stores and synaptic plasticity","volume":"32","author":"Fitzjohn","year":"2002","journal-title":"Cell Calcium"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib15","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/365456a0","article-title":"cGMP mobilizes intracellular Ca2+ in sea urchin eggs by stimulating cyclic ADP-ribose synthesis","volume":"365","author":"Galione","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib16","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1002\/jcp.22278","article-title":"Inward rectifier potassium channels in the HL-1 cardiomyocyte-derived cell line","volume":"225","author":"Goldoni","year":"2010","journal-title":"J.\u00a0Cell. Physiol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib17","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1016\/j.neuroscience.2009.11.071","article-title":"Presynaptic 5-HT(1B) receptor-mediated serotonergic inhibition of glutamate transmission in the bed nucleus of the stria terminalis","volume":"165","author":"Guo","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib18","doi-asserted-by":"crossref","first-page":"a004143","DOI":"10.1101\/cshperspect.a004143","article-title":"Regulation by Ca2+-signaling pathways of adenylyl cyclases","volume":"3","author":"Halls","year":"2011","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib19","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0306-3623(96)00173-5","article-title":"Recent studies on dendrotoxins and potassium ion channels","volume":"28","author":"Harvey","year":"1997","journal-title":"Gen. Pharmacol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib20","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.brainres.2005.12.053","article-title":"Lesions of the habenula produce stress- and dopamine-dependent alterations in prepulse inhibition and locomotion","volume":"1073-1074","author":"Heldt","year":"2006","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib21","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1111\/jnc.12227","article-title":"A\u00a0single in\u00a0vivo cocaine administration impairs 5-HT1B receptor-induced long-term depression in the nucleus accumbens","volume":"125","author":"Huang","year":"2013","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib22","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1085\/jgp.106.6.1069","article-title":"External barium block of Shaker potassium channels: evidence for two binding sites","volume":"106","author":"Hurst","year":"1995","journal-title":"J.\u00a0Gen. Physiol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib23","doi-asserted-by":"crossref","first-page":"13291","DOI":"10.1021\/bi981178p","article-title":"A\u00a0novel high-affinity inhibitor for inward-rectifier K+ channels","volume":"37","author":"Jin","year":"1998","journal-title":"Biochemistry"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib24","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0006-8993(89)90901-3","article-title":"Regulation of striatal serotonin release by the lateral habenula-dorsal raphe pathway in the rat as demonstrated by in\u00a0vivo microdialysis: role of excitatory amino acids and GABA","volume":"492","author":"Kal\u00e9n","year":"1989","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib25","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/cne.21951","article-title":"Topographic commissural and descending projections of the habenula in the rat","volume":"513","author":"Kim","year":"2009","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib26","first-page":"RA261","article-title":"Habenular and interpeduncularis nuclei: shared components in multiple-function networks","volume":"10","author":"Klemm","year":"2004","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib27","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/sj.npp.1301396","article-title":"Serotonergic modulation of GABAergic and glutamatergic synaptic transmission in mechanically isolated rat medial preoptic area neurons","volume":"33","author":"Lee","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib28","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1038\/nature09742","article-title":"Synaptic potentiation onto habenula neurons in the learned helplessness model of depression","volume":"470","author":"Li","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib29","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1152\/jn.1993.70.4.1451","article-title":"Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus","volume":"70","author":"Manabe","year":"1993","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib30","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/87865","article-title":"The cellular neurobiology of depression","volume":"7","author":"Manji","year":"2001","journal-title":"Nat. Med."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib31","doi-asserted-by":"crossref","first-page":"7402","DOI":"10.1523\/JNEUROSCI.6250-10.2011","article-title":"Serotonin induces long-term depression at corticostriatal synapses","volume":"31","author":"Mathur","year":"2011","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib32","doi-asserted-by":"crossref","first-page":"6300","DOI":"10.1016\/S0021-9258(19)84563-5","article-title":"Ryanodine activation and inhibition of the Ca2+ release channel of sarcoplasmic reticulum","volume":"261","author":"Meissner","year":"1986","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib68","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0006-8993(90)90502-3","article-title":"Localization of the mRNA for the 5-HT2 receptor by in situ hybridization histochemistry. Correlation with the distribution of receptor sites","volume":"524","author":"Mengod","year":"1990","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib33","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.neuroscience.2009.11.045","article-title":"Dopamine inhibits GABA(A) currents in ventral tegmental area dopamine neurons via activation of presynaptic G-protein coupled inwardly-rectifying potassium channels","volume":"165","author":"Michaeli","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib34","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1111\/j.1460-9568.2006.05063.x","article-title":"5-HT1B receptor-mediated presynaptic inhibition at the calyx of held of immature rats","volume":"24","author":"Mizutani","year":"2006","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib35","doi-asserted-by":"crossref","first-page":"2371","DOI":"10.1046\/j.1460-9568.1998.00248.x","article-title":"Serotonin inhibits synaptic glutamate currents in rat nucleus accumbens neurons via presynaptic 5-HT1B receptors","volume":"10","author":"Muramatsu","year":"1998","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib36","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/364076a0","article-title":"Cyclic ADP-ribose as an endogenous regulator of the non-skeletal type ryanodine receptor Ca2+ channel","volume":"364","author":"M\u00e9sz\u00e1ros","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib37","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0896-6273(00)80983-6","article-title":"Vesicle pools and Ca2+ microdomains: new tools for understanding their roles in neurotransmitter release","volume":"20","author":"Neher","year":"1998","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib38","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S0306-4522(97)00268-6","article-title":"Forebrain afferents to the rat dorsal raphe nucleus demonstrated by retrograde and anterograde tracing methods","volume":"82","author":"Peyron","year":"1998","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib39","doi-asserted-by":"crossref","first-page":"4034","DOI":"10.1523\/JNEUROSCI.19-10-04034.1999","article-title":"5-HT1B receptor-mediated presynaptic inhibition of retinal input to the suprachiasmatic nucleus","volume":"19","author":"Pickard","year":"1999","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib40","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0169-328X(94)90223-2","article-title":"Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors","volume":"23","author":"Pompeiano","year":"1994","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib41","doi-asserted-by":"crossref","first-page":"5951","DOI":"10.1523\/JNEUROSCI.16-19-05951.1996","article-title":"Induction of hippocampal long-term depression requires release of Ca2+ from separate presynaptic and postsynaptic intracellular stores","volume":"16","author":"Reyes","year":"1996","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib42","doi-asserted-by":"crossref","first-page":"4061","DOI":"10.1073\/pnas.96.7.4061","article-title":"Evidence of a role for cyclic ADP-ribose in long-term synaptic depression in hippocampus","volume":"96","author":"Reyes-Harde","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib43","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/S0028-3908(96)00052-4","article-title":"Serotonin modulates high-voltage-activated Ca2+ channels in rat ventromedial hypothalamic neurons","volume":"35","author":"Rhee","year":"1996","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib44","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0006-8993(97)00400-9","article-title":"Light and electron microscopic immunocytochemical visualization of 5-HT1B receptors in the rat brain","volume":"760","author":"Sari","year":"1997","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib45","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1016\/j.biopsych.2009.08.027","article-title":"Remission of major depression under deep brain stimulation of the lateral habenula in a therapy-refractory patient","volume":"67","author":"Sartorius","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib46","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/0143-4160(92)90055-W","article-title":"Ca2+\/calmodulin-regulated nitric oxide synthases","volume":"13","author":"Schmidt","year":"1992","journal-title":"Cell Calcium"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib47","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.neuron.2012.02.037","article-title":"Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin","volume":"74","author":"Shabel","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib48","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.neuroscience.2007.12.001","article-title":"5-HT inhibits synaptic transmission in rat subthalamic nucleus neurons in\u00a0vitro","volume":"151","author":"Shen","year":"2008","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib49","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1523\/JNEUROSCI.14-04-02408.1994","article-title":"Contrasting subcellular localization of the Kv1.2 K+ channel subunit in different neurons of rat brain","volume":"14","author":"Sheng","year":"1994","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib50","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/S0006-8993(02)04048-9","article-title":"Opposite metabolic changes in the habenula and ventral tegmental area of a genetic model of helpless behavior","volume":"963","author":"Shumake","year":"2003","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib51","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1113\/jphysiol.2002.022103","article-title":"The contribution of intracellular calcium stores to mEPSCs recorded in layer II neurones of rat barrel cortex","volume":"545","author":"Simkus","year":"2002","journal-title":"J.\u00a0Physiol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib52","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S0026-895X(25)09167-9","article-title":"k-Opioid receptor activation of a dendrotoxin-sensitive potassium channel mediates presynaptic inhibition of mossy fiber neurotransmitter release","volume":"50","author":"Simmons","year":"1996","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib53","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1016\/0028-3908(93)90021-T","article-title":"The nitric oxide-cyclic GMP signalling pathway in rat brain","volume":"32","author":"Southam","year":"1993","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib54","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0079-6123(08)61248-0","article-title":"Potassium currents in hippocampal pyramidal cells","volume":"83","author":"Storm","year":"1990","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0149-7634(82)90003-3","article-title":"The dorsal diencephalic conduction system: a review of the anatomy and functions of the habenular complex","volume":"6","author":"Sutherland","year":"1982","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib56","doi-asserted-by":"crossref","first-page":"9612","DOI":"10.1523\/JNEUROSCI.5583-03.2004","article-title":"Calcium release from presynaptic ryanodine-sensitive stores is required for long-term depression at hippocampal CA3-CA3 pyramidal neuron synapses","volume":"24","author":"Unni","year":"2004","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib57","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1046\/j.1460-9568.2003.02465.x","article-title":"Electrophysiological evidence for convergence of inputs from the medial prefrontal cortex and lateral habenula on single neurons in the dorsal raphe nucleus","volume":"17","author":"Varga","year":"2003","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib58","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/(SICI)1096-9861(19990517)407:4<555::AID-CNE7>3.0.CO;2-E","article-title":"Projections of the median raphe nucleus in the rat","volume":"407","author":"Vertes","year":"1999","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib59","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0304-3940(97)00302-9","article-title":"Expression of 5-HT7 receptor mRNA in rat brain during postnatal development","volume":"227","author":"Vizuete","year":"1997","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib60","doi-asserted-by":"crossref","first-page":"4588","DOI":"10.1523\/JNEUROSCI.14-08-04588.1994","article-title":"Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain","volume":"14","author":"Wang","year":"1994","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib61","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1126\/science.194312","article-title":"Physiological evidence for habenula as major link between forebrain and midbrain raphe","volume":"197","author":"Wang","year":"1977","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2014.01.046_bib62","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.bbr.2010.07.034","article-title":"Pharmacological inhibition of the lateral habenula improves depressive-like behavior in an animal model of treatment resistant depression","volume":"216","author":"Winter","year":"2011","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib63","doi-asserted-by":"crossref","first-page":"36453","DOI":"10.1074\/jbc.M109.075523","article-title":"Aminopyridines potentiate synaptic and neuromuscular transmission by targeting the voltage-activated calcium channel beta subunit","volume":"284","author":"Wu","year":"2009","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib64","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/S0031-6997(24)01385-1","article-title":"G\u00a0protein regulation of potassium ion channels","volume":"50","author":"Yamada","year":"1998","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib65","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.bbr.2007.10.022","article-title":"Lateral habenula lesions improve the behavioral response in depressed rats via increasing the serotonin level in dorsal raphe nucleus","volume":"188","author":"Yang","year":"2008","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuropharm.2014.01.046_bib66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0031-6997(24)01312-7","article-title":"The sarcoplasmic reticulum Ca2+ channel\/ryanodine receptor: modulation by endogenous effectors, drugs and disease states","volume":"49","author":"Zucchi","year":"1997","journal-title":"Pharmacol. Rev."}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390814000537?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390814000537?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T20:13:01Z","timestamp":1746130381000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390814000537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":67,"alternative-id":["S0028390814000537"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2014.01.046","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"5HT1B receptor-mediated pre-synaptic depression of excitatory inputs to the rat lateral habenula","name":"articletitle","label":"Article Title"},{"value":"Neuropharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuropharm.2014.01.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}