{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T16:21:33Z","timestamp":1778170893594,"version":"3.51.4"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,8,18]],"date-time":"2014-08-18T00:00:00Z","timestamp":1408320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100004281","name":"Narodowe Centrum Nauki","doi-asserted-by":"publisher","award":["2011\/03\/B\/NZ4\/00042"],"award-info":[{"award-number":["2011\/03\/B\/NZ4\/00042"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004281","name":"Narodowe Centrum Nauki","doi-asserted-by":"publisher","award":["2012\/06\/A\/NZ4\/00028"],"award-info":[{"award-number":["2012\/06\/A\/NZ4\/00028"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.neuropharm.2014.08.001","type":"journal-article","created":{"date-parts":[[2014,8,27]],"date-time":"2014-08-27T00:00:28Z","timestamp":1409097628000},"page":"301-310","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["Minocycline prevents dynorphin-induced neurotoxicity during neuropathic pain in rats"],"prefix":"10.1016","volume":"86","author":[{"given":"Ewelina","family":"Rojewska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wioletta","family":"Makuch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Przewlocka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna","family":"Mika","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2014.08.001_bib1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jneuroim.2010.08.013","article-title":"The neuroimmune balance in neuropathic pain: involvement of inflammatory immune cells, immune-like glial cells and cytokines","volume":"15","author":"Austin","year":"2010","journal-title":"J.\u00a0Neuroimmunol."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib2","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0304-3959(88)90209-6","article-title":"A\u00a0peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man","volume":"33","author":"Bennett","year":"1988","journal-title":"Pain"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib3","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","article-title":"Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction","volume":"162","author":"Chomczynski","year":"1987","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0304-3959(00)00490-5","article-title":"The role of neuroinflammation and neuroimmune activation in persistent pain","volume":"1","author":"DeLeo","year":"2001","journal-title":"Pain"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib5","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.tips.2004.10.001","article-title":"Neuroprotection by tetracyclines","volume":"25","author":"Domercq","year":"2004","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib6","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/0006-8993(91)91231-O","article-title":"Up-regulation of opioid gene expression in spinal cord evoked by experimental nerve injuries and inflammation","volume":"560","author":"Draisci","year":"1991","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib7","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1111\/j.1600-6143.2012.04161.x","article-title":"Fibronectin-\u03b14\u03b21 interactions in hepatic cold ischemia and reperfusion injury: regulation of MMP-9 and MT1-MMP via the p38 MAPK pathway","volume":"12","author":"Duarte","year":"2012","journal-title":"Am. J. Transplant."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib8","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/0166-2236(92)90019-5","article-title":"Activity-dependent neuronal plasticity following tissue injury and inflammation","volume":"15","author":"Dubner","year":"1992","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib9","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/ana.410270111","article-title":"Opioid and nonopioid mechanisms may contribute to dynorphin's pathophysiological actions in spinal cord injury","volume":"27","author":"Faden","year":"1990","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib10","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1002\/ana.410170414","article-title":"Endogenous opioid immunoreactivity in rat spinal cord following traumatic injury","volume":"17","author":"Faden","year":"1985","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib11","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.bcp.2008.11.003","article-title":"Inhibitory modulation of the mitochondrial permeability transition by minocycline","volume":"77","author":"Gieseler","year":"2009","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib12","doi-asserted-by":"crossref","first-page":"4308","DOI":"10.1523\/JNEUROSCI.0003-06.2006","article-title":"Activated microglia contribute to the maintenance of chronic pain after spinal cord injury","volume":"26","author":"Hains","year":"2006","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib13","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/0024-3205(80)90084-3","article-title":"Behavioral effects and in\u00a0vivo degradation of intraventricularly administered dynorphin-(1-13) and D-Ala2-dynorphin-(1-11) in rats","volume":"27","author":"Herman","year":"1980","journal-title":"Life Sci."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib14","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0014-2999(97)01492-1","article-title":"Mechanism of the dynorphin-induced dualistic effect on free intracellular Ca2+ concentration in cultured rat spinal neurons","volume":"342","author":"Hu","year":"1998","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib15","doi-asserted-by":"crossref","first-page":"2775","DOI":"10.1007\/s00125-006-0397-y","article-title":"Dynorphin A, kappa opioid receptors and the antinociceptive efficacy of asimadoline in streptozotocin-induced diabetic rats","volume":"49","author":"Jolivalt","year":"2006","journal-title":"Diabetologia"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib16","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/0196-9781(90)90187-A","article-title":"Dynorphin increases in the dorsal spinal cord in rats with a painful peripheral neuropathy","volume":"11","author":"Kajander","year":"1990","journal-title":"Peptides"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib17","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/nm1723","article-title":"Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain","volume":"14","author":"Kawasaki","year":"2008","journal-title":"Nat. Med."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib18","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.brainres.2010.11.038","article-title":"Effects of minocycline on Na+ currents in rat dorsal root ganglion neurons","volume":"25","author":"Kim","year":"2011","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib19","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/glia.1080","article-title":"Endogenous opioids and oligodendroglial function: possible autocrine\/paracrine effects on cell survival and development","volume":"35","author":"Knapp","year":"2001","journal-title":"Glia"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib20","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0304-3959(99)00195-5","article-title":"Cytokine involvement in dynorphin-induced allodynia","volume":"84","author":"Laughlin","year":"2000","journal-title":"Pain"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib21","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0304-3959(97)00046-8","article-title":"Spinally administered dynorphin A produces long-lasting allodynia: involvement of NMDA but not opioid receptors","volume":"72","author":"Laughlin","year":"1997","journal-title":"Pain"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib22","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.pain.2005.02.009","article-title":"Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation","volume":"115","author":"Ledeboer","year":"2005","journal-title":"Pain"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib23","doi-asserted-by":"crossref","first-page":"12325","DOI":"10.1523\/JNEUROSCI.2053-12.2012","article-title":"Repeated stress dysregulates \u03ba-opioid receptor signaling in the dorsal raphe through a p38\u03b1 MAPK-dependent mechanism","volume":"5","author":"Lemos","year":"2012","journal-title":"J.\u00a0Neurosci."},{"issue":"9","key":"10.1016\/j.neuropharm.2014.08.001_bib24","first-page":"16","article-title":"Enhancement by interleukin-1\u03b2 of AMPA and NMDA receptor-mediated currents in adult rat spinal superficial dorsal horn neurons","volume":"28","author":"Liu","year":"2013","journal-title":"Mol. Pain"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib25","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/S0022-3565(25)22198-X","article-title":"Neurological dysfunction after intrathecal injection of dynorphin A (1-13) in the rat. II. Nonopioid mechanisms mediate loss of motor, sensory and autonomic function","volume":"246","author":"Long","year":"1988","journal-title":"J.\u00a0Pharmacol. Exp. Ther."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib26","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1111\/j.1471-4159.2006.04370.x","article-title":"IL-4 attenuates the neuroinflammation induced by amyloid-beta in\u00a0vivo and in\u00a0vitro","volume":"101","author":"Lyons","year":"2007","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2202-7-56","article-title":"Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke","volume":"7","author":"Machado","year":"2006","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib28","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.npep.2007.06.001","article-title":"Targeting of opioid-producing leukocytes for pain control","volume":"41","author":"Machelska","year":"2007","journal-title":"Neuropeptides"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib29","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.neuropharm.2013.08.031","article-title":"Effects of selective and non-selective inhibitors of nitric oxide synthase on morphine- and endomorphin-1-induced analgesia in acute and neuropathic pain in rats","volume":"75","author":"Makuch","year":"2013","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib30","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0304-3959(00)00243-8","article-title":"Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats","volume":"86","author":"Malan","year":"2000","journal-title":"Pain"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib31","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.ejphar.2007.01.013","article-title":"Minocycline and pentoxifylline attenuate allodynia and hyperalgesia and potentiate the effects of morphine in rat and mouse models of neuropathic pain","volume":"560","author":"Mika","year":"2007","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib32","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.neuroscience.2010.11.040","article-title":"The effect of botulinum neurotoxin A on sciatic nerve injury-induced neuroimmunological changes in rat dorsal root ganglia and spinal cord","volume":"175","author":"Mika","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib33","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1016\/j.neuroscience.2009.11.064","article-title":"Minocycline reduces the injury-induced expression of prodynorphin and pronociceptin in the dorsal root ganglion in a rat model of neuropathic pain","volume":"165","author":"Mika","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib34","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.pain.2008.02.015","article-title":"Interleukin-1 alpha has antiallodynic and antihyperalgesic activities in a rat neuropathic pain model","volume":"138","author":"Mika","year":"2008","journal-title":"Pain"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib35","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.ejphar.2013.01.072","article-title":"Importance of glial activation in neuropathic pain","volume":"15","author":"Mika","year":"2013","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib36","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.neuint.2009.01.022","article-title":"Antioxidant potential of Minocycline in Japanese encephalitis virus infection in murine neuroblastoma cells: correlation with membrane fluidity and cell death","volume":"54","author":"Mishra","year":"2009","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib37","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1038\/sj.bjp.0705427","article-title":"Antagonists of the kappa-opioid receptor enhance allodynia in rats and mice after sciatic nerve ligation","volume":"140","author":"Obara","year":"2003","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib38","first-page":"135","article-title":"Naloxone prevents reduction of pain responses evoked by acupuncture in neuropathic rats","volume":"37","author":"Omana","year":"1994","journal-title":"Proc. West. Pharmacol. Soc."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib39","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.pain.2005.12.023","article-title":"Activation of glia and microglial p38 MAPK in medullary dorsal horn contributes to tactile hypersensitivity following trigeminal sensory nerve injury","volume":"121","author":"Piao","year":"2006","journal-title":"Pain"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib40","first-page":"37","article-title":"Prodynorphin gene expression in spinal cord is enhanced after traumatic injury in the rat","volume":"464","author":"Przew\u0142ocki","year":"1988","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib41","doi-asserted-by":"crossref","first-page":"3013","DOI":"10.2174\/1381612054865055","article-title":"Opioids in neuropathic pain","volume":"11","author":"Przewlocki","year":"2005","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib42","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0143-4179(83)90019-7","article-title":"Mixed opioid\/nonopioid effects of dynorphin and dynorphin related peptides after their intrathecal injection in rats","volume":"3","author":"Przew\u0142ocki","year":"1983","journal-title":"Neuropeptides"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib43","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S0304-3959(03)00138-6","article-title":"Anti-hyperalgesic and morphine-sparing actions of propentofylline following peripheral nerve injury in rats: mechanistic implications of spinal glia and proinflammatory cytokines","volume":"104","author":"Raghavendra","year":"2003","journal-title":"Pain"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib44","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/0306-4522(84)90175-1","article-title":"The immunohistochemical localization of nine peptides in the sacral parasympathetic nucleus and the dorsal gray commissure in rat spinal cord","volume":"12","author":"Sasek","year":"1984","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib45","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1126\/science.2569236","article-title":"Brain region and gene specificity of neuropeptide gene expression in cultured astrocytes","volume":"245","author":"Shinoda","year":"1989","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib46","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/S0022-3565(25)24330-0","article-title":"Dynorphin A and related peptides administered intrathecally in the rat: a search for putative kappa opiate receptor activity","volume":"238","author":"Stevens","year":"1986","journal-title":"J.\u00a0Pharmacol. Exp. Ther."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib47","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0006-8993(02)03180-3","article-title":"Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism","volume":"952","author":"Tan-No","year":"2002","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib48","doi-asserted-by":"crossref","first-page":"3753","DOI":"10.4049\/jimmunol.166.12.7527","article-title":"Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia","volume":"166","author":"Tikka","year":"2001","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib49","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0304-3959(96)03225-3","article-title":"Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: blockade by MK-801 but not naloxone","volume":"68","author":"Vanderah","year":"1996","journal-title":"Pain"},{"key":"10.1016\/j.neuropharm.2014.08.001_bib50","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1016\/0024-3205(82)90219-3","article-title":"Dynorphin (1-17): lack of analgesia but evidence for non-opiate electrophysiological and motor effects","volume":"31","author":"Walker","year":"1982","journal-title":"Life Sci."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib51","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1111\/j.1745-7254.2005.00152.x","article-title":"Interleukin-1 beta induction of neuron apoptosis depends on p38 mitogen-activated protein kinase activity after spinal cord injury","volume":"26","author":"Wang","year":"2005","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib52","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1002\/jnr.21971","article-title":"Effects of acute agonist treatment on subcellular distribution of kappa opioid receptor in rat spinal cord","volume":"15","author":"Wang","year":"2009","journal-title":"J.\u00a0Neurosci. Res."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib53","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1523\/JNEUROSCI.21-05-01779.2001","article-title":"Pronociceptive actions of dynorphin maintain chronic neuropathic pain","volume":"21","author":"Wang","year":"2001","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib54","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/0031-9384(76)90029-9","article-title":"Chronic catheterization of the spinal subarachnoid space","volume":"17","author":"Yaksh","year":"1976","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.neuropharm.2014.08.001_bib55","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0304-3959(83)90201-4","article-title":"Ethical guidelines for investigations of experimental pain in conscious animals","volume":"16","author":"Zimmermann","year":"1983","journal-title":"Pain"}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390814002846?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390814002846?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T23:56:59Z","timestamp":1762214219000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390814002846"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":55,"alternative-id":["S0028390814002846"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2014.08.001","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Minocycline prevents dynorphin-induced neurotoxicity during neuropathic pain in rats","name":"articletitle","label":"Article Title"},{"value":"Neuropharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuropharm.2014.08.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}