{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:08:53Z","timestamp":1791198533255,"version":"4.1.0"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100005725","name":"CHDI Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.neuropharm.2016.01.027","type":"journal-article","created":{"date-parts":[[2016,1,22]],"date-time":"2016-01-22T00:36:32Z","timestamp":1453422992000},"page":"298-307","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["A single dose of hypnotic corrects sleep and EEG abnormalities in symptomatic Huntington's disease mice"],"prefix":"10.1016","volume":"105","author":[{"given":"Sandor","family":"Kantor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janos","family":"Varga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Jennifer","family":"Morton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2016.01.027_bib1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.nurt.2008.01.008","article-title":"Symptomatic treatment of Huntington disease","volume":"5","author":"Adam","year":"2008","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib2","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1001\/archneur.65.4.482","article-title":"Rapid eye movement sleep disturbances in Huntington disease","volume":"65","author":"Arnulf","year":"2008","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib3","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1152\/physrev.00032.2011","article-title":"Control of sleep and wakefulness","volume":"92","author":"Brown","year":"2012","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02244546","article-title":"Effect of zolpidem on sleep and sleep EEG spectra in healthy young men","volume":"104","author":"Brunner","year":"1991","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib5","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1126\/science.1099745","article-title":"Neuronal oscillations in cortical networks","volume":"304","author":"Buzsaki","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib6","doi-asserted-by":"crossref","first-page":"3727","DOI":"10.1113\/JP270268","article-title":"Relationship between subthalamic nucleus neuronal activity and electrocorticogram is altered in the R6\/2 mouse model of Huntington's disease","volume":"593","author":"Callahan","year":"2015","journal-title":"J.\u00a0Physiol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib7","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1074\/jbc.M114.588608","article-title":"Amitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model","volume":"290","author":"Cong","year":"2015","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib8","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1152\/jn.00762.2011","article-title":"A\u00a0critical window of CAG repeat-length correlates with phenotype severity in the R6\/2 mouse model of Huntington's disease","volume":"107","author":"Cummings","year":"2012","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib9","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1755-5949.2010.00158.x","article-title":"Role of zolpidem in the management of insomnia","volume":"17","author":"Dang","year":"2011","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib10","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1055\/s-0030-1249049","article-title":"Impact of escitalopram on nocturnal sleep, day-time sleepiness and performance compared to amitriptyline: a randomized, double-blind, placebo-controlled study in healthy male subjects","volume":"43","author":"Doerr","year":"2010","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib11","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.nbd.2008.10.009","article-title":"CAG repeat lengths > or\u00a0=335 attenuate the phenotype in the R6\/2 Huntington's disease transgenic mouse","volume":"33","author":"Dragatsis","year":"2009","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib12","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/35094565","article-title":"Dynamic predictions: oscillations and synchrony in top-down processing","volume":"2","author":"Engel","year":"2001","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib13","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0165-0173(03)00178-4","article-title":"Is synchronized neuronal gamma activity relevant for selective attention?","volume":"42","author":"Fell","year":"2003","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib14","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1093\/brain\/awl040","article-title":"Parameter-based assessment of spatial and non-spatial attentional deficits in Huntington's disease","volume":"129","author":"Finke","year":"2006","journal-title":"Brain"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib15","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1093\/brain\/awt132","article-title":"Longitudinal analysis of the electroencephalogram and sleep phenotype in the R6\/2 mouse model of Huntington's disease","volume":"136","author":"Fisher","year":"2013","journal-title":"Brain"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib16","article-title":"Quantitative electroencephalographic analysis provides an early-stage indicator of disease onset and progression in the zQ175 knock-in mouse model of Huntington disease","author":"Fisher","year":"2015","journal-title":"Sleep"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib17","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0304-3940(94)91034-0","article-title":"High-frequency components of the rat electrocorticogram are modulated by the vigilance states","volume":"167","author":"Franken","year":"1994","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib18","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/cne.20087","article-title":"GABAergic basal forebrain neurons that express receptor for neurokinin B and send axons to the cerebral cortex","volume":"473","author":"Furuta","year":"2004","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib19","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s11910-010-0163-x","article-title":"Asymptomatic sleep abnormalities are a common early feature in patients with Huntington's disease","volume":"11","author":"Goodman","year":"2011","journal-title":"Curr. Neurol. Neurosci. Rep."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib20","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1046\/j.1471-4159.2003.01916.x","article-title":"Changes in GAD67 mRNA expression evidenced by in situ hybridization in the brain of R6\/2 transgenic mice","volume":"86","author":"Gourfinkel-An","year":"2003","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib21","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/(SICI)1096-9861(19970630)383:2<163::AID-CNE4>3.0.CO;2-Z","article-title":"GABAergic and other noncholinergic basal forebrain neurons, together with cholinergic neurons, project to the mesocortex and isocortex in the rat","volume":"383","author":"Gritti","year":"1997","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib22","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1162\/08989290260138636","article-title":"Modulation of induced gamma band responses in a perceptual learning task in the human EEG","volume":"14","author":"Gruber","year":"2002","journal-title":"J.\u00a0Cogn. Neurosci."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib23","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1136\/jnnp-2011-301732","article-title":"Cognitive domains that predict time to diagnosis in prodromal Huntington disease","volume":"83","author":"Harrington","year":"2012","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib24","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1093\/brain\/awh165","article-title":"Neural correlates associated with impaired disgust processing in pre-symptomatic Huntington's disease","volume":"127","author":"Hennenlotter","year":"2004","journal-title":"Brain"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib25","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1016\/j.clinph.2005.07.007","article-title":"Human EEG gamma oscillations in neuropsychiatric disorders","volume":"116","author":"Herrmann","year":"2005","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib26","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1212\/01.WNL.0000098878.47789.BD","article-title":"Profile of cognitive progression in early Huntington's disease","volume":"61","author":"Ho","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib27","doi-asserted-by":"crossref","first-page":"e47026","DOI":"10.1371\/journal.pone.0047026","article-title":"Dysfunctional behavioral modulation of corticostriatal communication in the R6\/2 mouse model of Huntington's disease","volume":"7","author":"Hong","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib28","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/mds.870110204","article-title":"Unified Huntington's disease rating scale: reliability and consistency","volume":"11","author":"Huntington Study Group","year":"1996","journal-title":"Mov. Disord."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib29","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/cne.20444","article-title":"Vglut2 afferents to the medial prefrontal and primary somatosensory cortices: a combined retrograde tracing in situ hybridization study [corrected]","volume":"483","author":"Hur","year":"2005","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib30","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1097\/chi.0b013e31802ed8c9","article-title":"Huntington's disease presenting as a depressive disorder with psychotic features","volume":"46","author":"Jardri","year":"2007","journal-title":"J.\u00a0Am. Acad. Child. Adolesc. Psychiatry"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib31","doi-asserted-by":"crossref","first-page":"e79509","DOI":"10.1371\/journal.pone.0079509","article-title":"beta oscillation during slow wave sleep and rapid eye movement sleep in the electroencephalogram of a transgenic mouse model of Huntington's disease","volume":"8","author":"Jeantet","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib32","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1093\/brain\/awt128","article-title":"Progressive sleep and electroencephalogram changes in mice carrying the Huntington's disease mutation","volume":"136","author":"Kantor","year":"2013","journal-title":"Brain"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib33","doi-asserted-by":"crossref","first-page":"3535","DOI":"10.1073\/pnas.1413625112","article-title":"Cortically projecting basal forebrain parvalbumin neurons regulate cortical gamma band oscillations","volume":"112","author":"Kim","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib34","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1097\/00001756-200410050-00031","article-title":"Sleep EEG changes after zolpidem in mice","volume":"15","author":"Kopp","year":"2004","journal-title":"Neuroreport"},{"issue":"Pt 7","key":"10.1016\/j.neuropharm.2016.01.027_bib35","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1093\/brain\/123.7.1349","article-title":"Visual object and visuospatial cognition in Huntington's disease: implications for information processing in corticostriatal circuits","volume":"123","author":"Lawrence","year":"2000","journal-title":"Brain"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib36","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1002\/ana.24495","article-title":"Sleep, but no metabolic, deficits in pre-manifest huntington's disease","volume":"78","author":"Lazar","year":"2015","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib37","doi-asserted-by":"crossref","first-page":"e0126972","DOI":"10.1371\/journal.pone.0126972","article-title":"Sleep physiology alterations precede plethoric phenotypic changes in R6\/1 Huntington's disease mice","volume":"10","author":"Lebreton","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib38","first-page":"935","article-title":"Cognitive changes in patients with Huntington's disease (HD) and asymptomatic carriers of the HD mutation\u2013a longitudinal follow-up study","volume":"251","author":"Lemiere","year":"2004","journal-title":"J.\u00a0Neurol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib39","doi-asserted-by":"crossref","first-page":"e69993","DOI":"10.1371\/journal.pone.0069993","article-title":"The Q175 mouse model of Huntington's disease shows gene dosage- and age-related decline in circadian rhythms of activity and sleep","volume":"8","author":"Loh","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib40","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/nature04767","article-title":"A\u00a0putative flip-flop switch for control of REM sleep","volume":"441","author":"Lu","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib41","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.conb.2013.02.006","article-title":"Paradoxical (REM) sleep genesis by the brainstem is under hypothalamic control","volume":"23","author":"Luppi","year":"2013","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib42","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3389\/fnsys.2011.00026","article-title":"Dysregulated neuronal activity patterns implicate corticostriatal circuit dysfunction in multiple rodent models of Huntington's disease","volume":"5","author":"Miller","year":"2011","journal-title":"Front. Syst. Neurosci."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib43","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.expneurol.2012.10.014","article-title":"Circadian and sleep disorder in Huntington's disease","volume":"243","author":"Morton","year":"2013","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib44","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.nbd.2008.11.015","article-title":"Paradoxical delay in the onset of disease caused by super-long CAG repeat expansions in R6\/2 mice","volume":"33","author":"Morton","year":"2009","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib45","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.expneurol.2014.10.001","article-title":"Application of neurophysiological biomarkers for Huntington's disease: evaluating a phosphodiesterase 9A inhibitor","volume":"263","author":"Nagy","year":"2015","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib46","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1177\/0269881109106927","article-title":"Searching for perfect sleep: the continuing evolution of GABAA receptor modulators as hypnotics","volume":"24","author":"Nutt","year":"2010","journal-title":"J.\u00a0Psychopharmacol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib47","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0028-3908(85)90078-4","article-title":"Effects of acute and chronic treatment with amitryptyline on the sleep-wake activity of rats","volume":"24","author":"Obal","year":"1985","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib48","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.nbd.2012.07.015","article-title":"\u201cEctopic\u201d theta oscillations and interictal activity during slow-wave state in the R6\/1 mouse model of Huntington's disease","volume":"48","author":"Pignatelli","year":"2012","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib49","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.1460-9568.2009.07062.x","article-title":"Basal ganglia control of sleep-wake behavior and cortical activation","volume":"31","author":"Qiu","year":"2010","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib50","article-title":"Nigrostriatal dopamine acting on globus pallidus regulates sleep","author":"Qiu","year":"2014","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib51","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.neuroscience.2005.08.062","article-title":"Hyperactive striatal neurons in symptomatic Huntington R6\/2 mice: variations with behavioral state and repeated ascorbate treatment","volume":"137","author":"Rebec","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib52","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1046\/j.1471-4159.1999.721773.x","article-title":"Brain neurotransmitter deficits in mice transgenic for the Huntington's disease mutation","volume":"72","author":"Reynolds","year":"1999","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib53","doi-asserted-by":"crossref","first-page":"10369","DOI":"10.1523\/JNEUROSCI.1839-04.2004","article-title":"Short- and long-term effects of cholinergic modulation on gamma oscillations and response synchronization in the visual cortex","volume":"24","author":"Rodriguez","year":"2004","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib54","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S1474-4422(10)70245-3","article-title":"Huntington's disease: from molecular pathogenesis to clinical treatment","volume":"10","author":"Ross","year":"2011","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib55","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1023\/A:1006986824213","article-title":"Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding","volume":"19","author":"Sanchez","year":"1999","journal-title":"Cell Mol. Neurobiol."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib56","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1038\/79848","article-title":"Cellular and network mechanisms of rhythmic recurrent activity in neocortex","volume":"3","author":"Sanchez-Vives","year":"2000","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib57","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1046\/j.1460-9568.2002.02004.x","article-title":"The neglected constituent of the basal forebrain corticopetal projection system: GABAergic projections","volume":"15","author":"Sarter","year":"2002","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib58","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0987-7053(96)81034-3","article-title":"Sleep features in Tourette's syndrome, neuroacanthocytosis and Huntington's chorea","volume":"25","author":"Silvestri","year":"1995","journal-title":"Neurophysiol. Clin."},{"issue":"Pt 5","key":"10.1016\/j.neuropharm.2016.01.027_bib59","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1093\/brain\/119.5.1647","article-title":"Loss of disgust. Perception of faces and emotions in Huntington's disease","volume":"119","author":"Sprengelmeyer","year":"1996","journal-title":"Brain"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib60","first-page":"470","article-title":"Acute, subchronic and withdrawal sleep EEG changes during treatment with paroxetine and amitriptyline: a double-blind randomized trial in major depression","volume":"18","author":"Staner","year":"1995","journal-title":"Sleep"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib61","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1523\/JNEUROSCI.16-01-00392.1996","article-title":"Synchronization of fast (30-40 Hz) spontaneous cortical rhythms during brain activation","volume":"16","author":"Steriade","year":"1996","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1037\/a0020937","article-title":"Neurocognitive signs in prodromal Huntington disease","volume":"25","author":"Stout","year":"2011","journal-title":"Neuropsychology"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib63","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/0092-8674(93)90585-E","article-title":"A\u00a0novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes","volume":"72","author":"The Huntington's Disease Collaborative Research Group","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib64","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.1046\/j.1460-9568.2000.00199.x","article-title":"Unrelated course of subthalamic nucleus and globus pallidus neuronal activities across vigilance states in the rat","volume":"12","author":"Urbain","year":"2000","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib65","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3389\/fnana.2010.00145","article-title":"Role of Basal Ganglia in sleep-wake regulation: neural circuitry and clinical significance","volume":"4","author":"Vetrivelan","year":"2010","journal-title":"Front. Neuroanat."},{"key":"10.1016\/j.neuropharm.2016.01.027_bib66","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/nature14979","article-title":"Control of REM sleep by ventral medulla GABAergic neurons","volume":"526","author":"Weber","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2016.01.027_bib67","doi-asserted-by":"crossref","first-page":"927","DOI":"10.2165\/00003495-200565070-00003","article-title":"Antidepressants and sleep: a qualitative review of the literature","volume":"65","author":"Wilson","year":"2005","journal-title":"Drugs"}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390816300260?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390816300260?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T06:48:20Z","timestamp":1758437300000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390816300260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":67,"alternative-id":["S0028390816300260"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2016.01.027","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A single dose of hypnotic corrects sleep and EEG abnormalities in symptomatic Huntington's disease mice","name":"articletitle","label":"Article Title"},{"value":"Neuropharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuropharm.2016.01.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}