{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T22:44:13Z","timestamp":1789685053599,"version":"4.0.1"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003500","name":"University of Padova","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003500","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002915","name":"Fondation pour la Recherche M\u00e9dicale","doi-asserted-by":"crossref","award":["DPA20140629794"],"award-info":[{"award-number":["DPA20140629794"]}],"id":[{"id":"10.13039\/501100002915","id-type":"DOI","asserted-by":"crossref"}]},{"name":"University of Bordeaux and the CNRS"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.neuropharm.2017.01.024","type":"journal-article","created":{"date-parts":[[2017,1,27]],"date-time":"2017-01-27T13:16:59Z","timestamp":1485523019000},"page":"41-48","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["CRF1 receptor-deficiency increases cocaine reward"],"prefix":"10.1016","volume":"117","author":[{"given":"Angelo","family":"Contarino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Kitchener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique","family":"Vall\u00e9e","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Papaleo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier-Vincenzo","family":"Piazza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2017.01.024_bib1","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/0306-4522(90)90244-X","article-title":"Charting of type II glucocorticoid receptor-like immunoreactivity in the rat central nervous system","volume":"39","author":"Ahima","year":"1990","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib2","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1146\/annurev.pharmtox.44.101802.121410","article-title":"CRF and CRF receptors: role in stress responsivity and other behaviors","volume":"44","author":"Bale","year":"2004","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib3","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/S0149-7634(99)00031-7","article-title":"Cocaine potentiates defensive behaviors related to fear and anxiety","volume":"23","author":"Blanchard","year":"1999","journal-title":"Neurosci. Biobehav Rev."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib4","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0149-7634(98)00019-0","article-title":"Acute cocaine effects on stereotype and defense: an ethoexperimental approach","volume":"23","author":"Blanchard","year":"1998","journal-title":"Neurosci. Biobehav Rev."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib5","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.1210\/endo.141.8.7606","article-title":"Modulation of urocortin-induced hypophagia and weight loss by corticotropin-releasing factor receptor 1 deficiency in mice","volume":"141","author":"Bradbury","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.brainres.2009.11.002","article-title":"Molecular and genetic substrates linking stress and addiction","volume":"1314","author":"Briand","year":"2010","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib7","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/0306-4522(93)90144-5","article-title":"Modulation of the locomotor response to amphetamine by corticosterone","volume":"56","author":"Cador","year":"1993","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0006-8993(98)01158-5","article-title":"Reduced anxiety-like and cognitive performance in mice lacking the corticotropin-releasing factor receptor 1","volume":"835","author":"Contarino","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib9","doi-asserted-by":"crossref","first-page":"2698","DOI":"10.1210\/endo.141.7.7653","article-title":"Dissociation of locomotor activation and suppression of food intake induced by CRF in CRFR1-deficient mice","volume":"141","author":"Contarino","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib10","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1054\/npep.2002.0899","article-title":"Targeted mutations of the corticotropin-releasing factor system: effects on physiology and behavior","volume":"36","author":"Contarino","year":"2002","journal-title":"Neuropeptides"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib11","doi-asserted-by":"crossref","first-page":"18649","DOI":"10.1073\/pnas.0506999102","article-title":"The corticotropin-releasing factor receptor-1 pathway mediates the negative affective states of opiate withdrawal","volume":"102","author":"Contarino","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib12","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.bbr.2006.11.015","article-title":"Adrenalectomy prevents behavioural sensitisation of mice to cocaine in a genotype-dependent manner","volume":"177","author":"de Jong","year":"2007","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib13","first-page":"51","article-title":"Hormones, brain and stress","volume":"37","author":"de Kloet","year":"2003","journal-title":"Endocr. Regul."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib14","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/S0022-3565(24)36712-6","article-title":"Glucocorticoids and behavioral effects of psychostimulants. II: cocaine intravenous self-administration and reinstatement depend on glucocorticoid levels","volume":"281","author":"Deroche","year":"1997","journal-title":"J.\u00a0Pharmacol. Exp. Ther."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib15","doi-asserted-by":"crossref","first-page":"5529","DOI":"10.1523\/JNEUROSCI.18-14-05529.1998","article-title":"The role of corticotropin-releasing factor and corticosterone in stress- and cocaine-induced relapse to cocaine seeking in rats","volume":"18","author":"Erb","year":"1998","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib16","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1210\/endo-117-5-1803","article-title":"Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptor","volume":"117","author":"Fuxe","year":"1985","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib17","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1126\/science.2011738","article-title":"Cocaine addiction: psychology and neurophysiology","volume":"251","author":"Gawin","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib18","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0376-8716(90)90147-7","article-title":"Concurrent and simultaneous use of alcohol with cocaine: results of national survey","volume":"25","author":"Grant","year":"1990","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib19","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s002130000650","article-title":"Chronic unpredictable stress, but not chronic predictable stress, enhances the sensitivity to the behavioral effects of cocaine in rats","volume":"154","author":"Haile","year":"2001","journal-title":"Psychopharmacol. Berl."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib20","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1124\/pr.55.1.3","article-title":"International Union of Pharmacology. XXXVI. Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands","volume":"55","author":"Hauger","year":"2003","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib21","doi-asserted-by":"crossref","first-page":"7462","DOI":"10.1523\/JNEUROSCI.18-18-07462.1998","article-title":"Regulation of hippocampal glucocorticoid receptor gene transcription and protein expression in\u00a0vivo","volume":"18","author":"Herman","year":"1998","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib22","doi-asserted-by":"crossref","first-page":"4093","DOI":"10.1523\/JNEUROSCI.2232-15.2016","article-title":"Episodic social stress-escalated cocaine self-administration: role of phasic and tonic corticotropin releasing factor in the anterior and posterior ventral tegmental area","volume":"36","author":"Holly","year":"2016","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib23","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s002130000451","article-title":"Leftward shift in the acquisition of cocaine self-administration in isolation-reared rats: relationship to extracellular levels of dopamine, serotonin and glutamate in the nucleus accumbens and amygdala-striatal FOS expression","volume":"151","author":"Howes","year":"2000","journal-title":"Psychopharmacol. Berl."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib24","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1111\/j.1460-9568.2004.03267.x","article-title":"Differences between brain structures in nuclear translocation and DNA binding of the glucocorticoid receptor during stress and the circadian cycle","volume":"19","author":"Kitchener","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib25","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.neuron.2008.06.012","article-title":"A\u00a0role for brain stress systems in addiction","volume":"59","author":"Koob","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib56","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib26","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1046\/j.1471-4159.2003.01635.x","article-title":"Dopamine-dependent responses to cocaine depend on corticotropin-releasing factor receptor subtypes","volume":"84","author":"Lu","year":"2003","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib27","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0143-4179(03)00021-0","article-title":"Morphine and cocaine influence on CRF biosynthesis in the rat central nucleus of amygdala","volume":"37","author":"Maj","year":"2003","journal-title":"Neuropeptides"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib28","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1016\/S0022-3565(24)36711-4","article-title":"Glucocorticoids and behavioral effects of psychostimulants. I: locomotor response to cocaine depends on basal levels of glucocorticoids","volume":"281","author":"Marinelli","year":"1997","journal-title":"J.\u00a0Pharmacol. Exp. Ther."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib29","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1080\/13556219971894","article-title":"The corticosteroid synthesis inhibitor metyrapone markedly enhances the behavioural effects of d-amphetamine","volume":"4","author":"Marrow","year":"1999","journal-title":"Addict. Biol."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib30","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1056\/NEJM199604113341507","article-title":"Management of cocaine abuse and dependence","volume":"334","author":"Mendelson","year":"1996","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib31","doi-asserted-by":"crossref","first-page":"3965","DOI":"10.1007\/s00213-014-3534-1","article-title":"CRF1 receptor-deficiency induces anxiety-like vulnerability to cocaine","volume":"231","author":"Morisot","year":"2014","journal-title":"Psychopharmacol. Berl."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib32","doi-asserted-by":"crossref","first-page":"2878","DOI":"10.1038\/npp.2008.8","article-title":"Disruption of the CRF(2) receptor pathway decreases the somatic expression of opiate withdrawal","volume":"33","author":"Papaleo","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib33","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.neuron.2007.01.022","article-title":"Disruption of the CRF\/CRF1 receptor stress system exacerbates the somatic signs of opiate withdrawal","volume":"53","author":"Papaleo","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib34","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0165-6147(97)01115-2","article-title":"The role of stress in drug self-administration","volume":"19","author":"Piazza","year":"1998","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib35","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0304-3940(95)11365-4","article-title":"Sensitization of cocaine-stimulated increase in extracellular levels of corticotropin-releasing factor from the rat amygdala after repeated administration as determined by intracranial microdialysis","volume":"187","author":"Richter","year":"1995","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib36","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1006\/mcne.1994.1021","article-title":"Stimulatory effect of cocaine on ACTH secretion: role of the hypothalamus","volume":"5","author":"Rivier","year":"1994","journal-title":"Mol. Cell Neurosci."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib37","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/0006-8993(87)90953-X","article-title":"Cocaine stimulates adrenocorticotropin (ACTH) secretion through a corticotropin-releasing factor (CRF)-mediated mechanism","volume":"422","author":"Rivier","year":"1987","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib38","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.neuroscience.2007.09.043","article-title":"Corticotropin-releasing factor projections from limbic forebrain and paraventricular nucleus of the hypothalamus to the region of the ventral tegmental area","volume":"150","author":"Rodaros","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib39","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/0091-3057(92)90203-R","article-title":"Anxiogenic properties of cocaine in the rat evaluated with the elevated plus-maze","volume":"43","author":"Rogerio","year":"1992","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib40","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S0006-8993(03)02346-1","article-title":"Sex differences in the conditioned rewarding effects of cocaine","volume":"970","author":"Russo","year":"2003","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib41","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0021-9258(18)48448-7","article-title":"Heat shock induces translocation to the nucleus of the unliganded glucocorticoid receptor","volume":"267","author":"Sanchez","year":"1992","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib42","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/0006-8993(92)91176-F","article-title":"The cocaine-induced elevation of plasma corticosterone is mediated by endogenous corticotropin-releasing factor (CRF) in rats","volume":"589","author":"Sarnyai","year":"1992","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib43","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/S0896-6273(00)80491-2","article-title":"Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development","volume":"20","author":"Smith","year":"1998","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib44","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0166-4328(96)02257-7","article-title":"Behavioral stereotypies induced by \u201dbinge' cocaine administration are independent of drug-induced increases in corticosterone levels","volume":"86","author":"Spangler","year":"1997","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib45","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s00213-007-0983-9","article-title":"CRF(1) receptor antagonists attenuate escalated cocaine self-administration in rats","volume":"196","author":"Specio","year":"2008","journal-title":"Psychopharmacol. Berl."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib46","doi-asserted-by":"crossref","first-page":"PL339","DOI":"10.1016\/0024-3205(95)00098-4","article-title":"Adrenalectomy potentiates the morphine\u2013but not cocaine-induced place preference in rats","volume":"56","author":"Suzuki","year":"1995","journal-title":"Life Sci."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib47","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/520","article-title":"Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1","volume":"19","author":"Timpl","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib48","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1369-1600.2007.00070.x","article-title":"Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade","volume":"12","author":"Tzschentke","year":"2007","journal-title":"Addict. Biol."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib49","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/j.1600-0854.2011.01288.x","article-title":"On the trail of the glucocorticoid receptor: into the nucleus and back","volume":"13","author":"Vandevyver","year":"2012","journal-title":"Traffic"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib50","doi-asserted-by":"crossref","first-page":"5747","DOI":"10.1210\/endo.137.12.8940412","article-title":"In\u00a0vivo and in\u00a0vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation","volume":"137","author":"Webster","year":"1996","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib51","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.biopsych.2011.07.009","article-title":"Early-life forebrain glucocorticoid receptor overexpression increases anxiety behavior and cocaine sensitization","volume":"71","author":"Wei","year":"2012","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.neuropharm.2017.01.024_bib52","doi-asserted-by":"crossref","first-page":"11851","DOI":"10.1073\/pnas.0402208101","article-title":"Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability","volume":"101","author":"Wei","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib53","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0376-8716(96)01324-5","article-title":"Adverse effects of stimulant drugs in a community sample of drug users","volume":"44","author":"Williamson","year":"1997","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib54","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/0091-3057(92)90386-T","article-title":"Anxiogenic effects of acute and chronic cocaine administration: neurochemical and behavioral studies","volume":"41","author":"Yang","year":"1992","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.neuropharm.2017.01.024_bib55","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1517\/13543784.13.7.799","article-title":"The therapeutic potential of CRF1 antagonists for anxiety","volume":"13","author":"Zorrilla","year":"2004","journal-title":"Expert Opin. Investig. Drugs"}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390817300254?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390817300254?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T06:47:23Z","timestamp":1758437243000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390817300254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":56,"alternative-id":["S0028390817300254"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2017.01.024","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CRF1 receptor-deficiency increases cocaine reward","name":"articletitle","label":"Article Title"},{"value":"Neuropharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuropharm.2017.01.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}