{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:30:16Z","timestamp":1792787416793,"version":"4.5.0"},"reference-count":138,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Agence Nationale de la Recherche Scientifique","id":[{"id":"https:\/\/ror.org\/00rbzpz17","id-type":"ROR","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002915","name":"The Fondation Pour La Recherche M\u00e9dicale","doi-asserted-by":"crossref","award":["20160334896"],"award-info":[{"award-number":["20160334896"]}],"id":[{"id":"10.13039\/501100002915","id-type":"DOI","asserted-by":"crossref"}]},{"name":"IMPRiND","award":["116060"],"award-info":[{"award-number":["116060"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1016\/j.neuropharm.2018.12.008","type":"journal-article","created":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T03:43:37Z","timestamp":1544499817000},"page":"107461","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":68,"special_numbering":"C","title":["Cell biology and dynamics of Neuronal Na+\/K+-ATPase in health and diseases"],"prefix":"10.1016","volume":"169","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1322-8018","authenticated-orcid":false,"given":"Amulya Nidhi","family":"Shrivastava","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Triller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald","family":"Melki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2018.12.008_bib1","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.ebiom.2017.06.011","article-title":"Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na+,K+-ATPase Blocks HIV-1 Infection","volume":"21","author":"Agostini","year":"2017","journal-title":"EBioMedicine"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib2","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1007\/s12035-014-8975-3","article-title":"Functional Interaction Between Na\/K-ATPase and NMDA Receptor in Cerebellar Neurons","volume":"52","author":"Akkuratov","year":"2015","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib3","doi-asserted-by":"crossref","first-page":"C491","DOI":"10.1152\/ajpcell.00359.2015","article-title":"Na+-K+-ATPase, a new class of plasma membrane receptors","volume":"310","author":"Aperia","year":"2016","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib4","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1074\/jbc.M112.425785","article-title":"A Specific and Essential Role for Na,K-ATPase \u03b13 in Neurons Co-expressing \u03b11 and \u03b13","volume":"288","author":"Azarias","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib5","doi-asserted-by":"crossref","first-page":"3264","DOI":"10.1093\/emboj\/cdf330","article-title":"FXYD7 is a brain-specific regulator of Na,K-ATPase alpha 1-beta isozymes","volume":"21","author":"B\u00e9guin","year":"2002","journal-title":"EMBO J."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib6","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1038\/347386a0","article-title":"Inhibition by dopamine of (Na(+)+K+)ATPase activity in neostriatal neurons through D1 and D2 dopamine receptor synergism","volume":"347","author":"Bertorello","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib7","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/embj.201386120","article-title":"Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting","volume":"33","author":"Biesemann","year":"2014","journal-title":"EMBO J."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib8","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1093\/hmg\/ddp170","article-title":"A C-terminal mutation of ATP1A3 underscores the crucial role of sodium affinity in the pathophysiology of rapid-onset dystonia-parkinsonism","volume":"18","author":"Blanco-Arias","year":"2009","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib9","first-page":"F633","article-title":"Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function","volume":"275","author":"Blanco","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib10","doi-asserted-by":"crossref","DOI":"10.1117\/1.NPh.3.4.041803","article-title":"Sodium pump organization in dendritic spines","volume":"3","author":"Blom","year":"2016","journal-title":"Neurophotonics"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib11","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/jemt.21046","article-title":"Nearest neighbor analysis of dopamine D1 receptors and Na(+)-K(+)-ATPases in dendritic spines dissected by STED microscopy","volume":"75","author":"Blom","year":"2012","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib12","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1471-2202-12-16","article-title":"Spatial distribution of Na+-K+-ATPase in dendritic spines dissected by nanoscale superresolution STED microscopy","volume":"12","author":"Blom","year":"2011","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib13","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.pediatrneurol.2014.08.015","article-title":"Identical ATP1A3 mutation causes alternating hemiplegia of childhood and rapid-onset dystonia parkinsonism phenotypes","volume":"51","author":"Boelman","year":"2014","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib14","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1002\/cne.22524","article-title":"Distribution of Na\/K-ATPase alpha 3 isoform, a sodium-potassium P-type pump associated with rapid-onset of dystonia parkinsonism (RDP) in the adult mouse brain","volume":"519","author":"B\u00f8ttger","year":"2011","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib15","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1093\/brain\/awl340","article-title":"The phenotypic spectrum of rapid-onset dystonia-parkinsonism (RDP) and mutations in the ATP1A3 gene","volume":"130","author":"Brashear","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib16","series-title":"ATP1A3-Related Neurologic Disorders","author":"Brashear","year":"2008"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib17","doi-asserted-by":"crossref","first-page":"9808","DOI":"10.1523\/JNEUROSCI.1788-16.2017","article-title":"Prying into the Prion Hypothesis for Parkinson's Disease","volume":"37","author":"Brundin","year":"2017","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib18","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/nrm2873","article-title":"Prion-like transmission of protein aggregates in neurodegenerative diseases","volume":"11","author":"Brundin","year":"2010","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib19","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1083\/jcb.200712022","article-title":"Regulation of caveolin-1 membrane trafficking by the Na\/K-ATPase","volume":"182","author":"Cai","year":"2008","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib20","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nn.2753","article-title":"The neural substrates of rapid-onset Dystonia-Parkinsonism","volume":"14","author":"Calderon","year":"2011","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib21","doi-asserted-by":"crossref","first-page":"967","DOI":"10.15252\/emmm.201505944","article-title":"Defective glutamate and K+ clearance by cortical astrocytes in familial hemiplegic migraine type 2","volume":"8","author":"Capuani","year":"2016","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib22","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/BF02800498","article-title":"Na,K-ATPase mRNA levels and plaque load in Alzheimer's disease","volume":"9","author":"Chauhan","year":"1997","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib23","article-title":"Missense variants in ATP1A3 and FXYD gene family are associated with childhood-onset schizophrenia","author":"Chaumette","year":"2018","journal-title":"Mol. Psychiatr."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib24","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1074\/jbc.274.4.1920","article-title":"Dopamine-induced endocytosis of Na+,K+-ATPase is initiated by phosphorylation of Ser-18 in the rat alpha subunit and Is responsible for the decreased activity in epithelial cells","volume":"274","author":"Chibalin","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib25","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.neuron.2013.10.013","article-title":"The dynamic synapse","volume":"80","author":"Choquet","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib26","doi-asserted-by":"crossref","first-page":"14085","DOI":"10.1073\/pnas.0904817106","article-title":"Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS","volume":"106","author":"Clapcote","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib27","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1042\/BST0390741","article-title":"The pumps that fuel a sperm's journey","volume":"39","author":"Clausen","year":"2011","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib28","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3389\/fphys.2017.00371","article-title":"The Structure and Function of the Na,K-ATPase Isoforms in Health and Disease","volume":"8","author":"Clausen","year":"2017","journal-title":"Front. Physiol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib29","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1074\/jbc.275.3.1976","article-title":"Transport and pharmacological properties of nine different human Na, K-ATPase isozymes","volume":"275","author":"Crambert","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib30","doi-asserted-by":"crossref","first-page":"14877","DOI":"10.1021\/bi001073y","article-title":"Participation of Na,K-ATPase in FGF-2 secretion: rescue of ouabain-inhibitable FGF-2 secretion by ouabain-resistant Na,K-ATPase alpha subunits","volume":"39","author":"Dahl","year":"2000","journal-title":"Biochemistry"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib31","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1111\/dmcn.12927","article-title":"Relapsing encephalopathy with cerebellar ataxia related to an ATP1A3 mutation","volume":"57","author":"Dard","year":"2015","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib32","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.neuron.2004.06.028","article-title":"Mutations in the Na+\/K+ -ATPase alpha3 gene ATP1A3 are associated with rapid-onset dystonia parkinsonism","volume":"43","author":"de Carvalho Aguiar","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib33","first-page":"45","article-title":"Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na\/K ATPase alpha3 Docking Station","volume":"90","author":"DiChiara","year":"2017","journal-title":"Yale J. Biol. Med."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib34","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1471-2202-6-7","article-title":"Dysregulation of Na+\/K+ ATPase by amyloid in APP+PS1 transgenic mice","volume":"6","author":"Dickey","year":"2005","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib35","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1146\/annurev.biophys.37.032807.125824","article-title":"Crowding effects on diffusion in solutions and cells","volume":"37","author":"Dix","year":"2008","journal-title":"Annu. Rev. Biophys."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib36","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/S0306-4522(02)00922-3","article-title":"Stretch receptor-associated expression of alpha 3 isoform of the Na+, K+-ATPase in rat peripheral nervous system","volume":"116","author":"Dobretsov","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib37","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S0006-8993(98)01361-4","article-title":"Non-uniform expression of alpha subunit isoforms of the Na+\/K+ pump in rat dorsal root ganglia neurons","volume":"821","author":"Dobretsov","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib38","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/S0306-4522(99)00122-0","article-title":"Functional Na+\/K+ pump in rat dorsal root ganglia neurons","volume":"93","author":"Dobretsov","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib39","doi-asserted-by":"crossref","first-page":"2373","DOI":"10.2741\/1704","article-title":"Neuronal function and alpha3 isoform of the Na\/K-ATPase","volume":"10","author":"Dobretsov","year":"2005","journal-title":"Front. Biosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib40","article-title":"Soluble Amyloid Precursor Protein Alpha Interacts with alpha3-Na, K-ATPAse to Induce Axonal Outgrowth but Not Neuroprotection: Evidence for Distinct Mechanisms Underlying these Properties","volume":"1\u201317","author":"Dorard","year":"2017","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib41","doi-asserted-by":"crossref","first-page":"9913","DOI":"10.1523\/JNEUROSCI.5584-12.2013","article-title":"Na+\/K+ ATPase \u03b11 and \u03b13 isoforms are differentially expressed in \u03b1- and \u03b3-motoneurons","volume":"33","author":"Edwards","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib42","doi-asserted-by":"crossref","first-page":"26245","DOI":"10.1074\/jbc.M110.123976","article-title":"The rapid-onset dystonia parkinsonism mutation D923N of the Na+, K+-ATPase alpha3 isoform disrupts Na+ interaction at the third Na+ site","volume":"285","author":"Einholm","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib43","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1523\/JNEUROSCI.23-01-00043.2003","article-title":"Global loss of Na,K-ATPase and its nitric oxide-mediated regulation in a transgenic mouse model of amyotrophic lateral sclerosis","volume":"23","author":"Ellis","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib44","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1074\/jbc.273.1.544","article-title":"The inhibition of fibroblast growth factor-2 export by cardenolides implies a novel function for the catalytic subunit of Na+,K+-ATPase","volume":"273","author":"Florkiewicz","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib45","doi-asserted-by":"crossref","first-page":"11723","DOI":"10.1523\/JNEUROSCI.1409-14.2014","article-title":"Abnormal high-frequency burst firing of cerebellar neurons in rapid-onset dystonia-parkinsonism","volume":"34","author":"Fremont","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib46","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.nbd.2015.06.004","article-title":"Aberrant Purkinje cell activity is the cause of dystonia in a shRNA-based mouse model of Rapid Onset Dystonia\u2013Parkinsonism","volume":"82","author":"Fremont","year":"2015","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib47","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1146\/annurev.physiol.68.040104.131852","article-title":"Role of FXYD proteins in ion transport","volume":"68","author":"Garty","year":"2006","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib48","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1146\/annurev-neuro-072116-031153","article-title":"Propagation of Tau Aggregates and Neurodegeneration","volume":"40","author":"Goedert","year":"2017","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib49","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.mce.2014.12.004","article-title":"Somatic mutations of the ATP1A1 gene and aldosterone-producing adenomas","volume":"408","author":"Gomez-Sanchez","year":"2015","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib50","doi-asserted-by":"crossref","first-page":"2394","DOI":"10.1093\/hmg\/ddm167","article-title":"A novel family of transmembrane proteins interacting with beta subunits of the Na,K-ATPase","volume":"16","author":"Gorokhova","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0026813","article-title":"Na+\/K+-ATPase is present in scrapie-associated fibrils, modulates PrP misfolding in vitro and links PrP function and dysfunction","volume":"6","author":"Graham","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib52","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.neuron.2012.08.019","article-title":"Synaptic Energy Use and Supply","volume":"75","author":"Harris","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib53","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1038\/ng.2358","article-title":"De novo mutations in ATP1A3 cause alternating hemiplegia of childhood","volume":"44","author":"Heinzen","year":"2012","journal-title":"Nat. Genet."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib54","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S1474-4422(14)70011-0","article-title":"Distinct neurological disorders with ATP1A3 mutations","volume":"13","author":"Heinzen","year":"2014","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib55","doi-asserted-by":"crossref","first-page":"16956","DOI":"10.1074\/jbc.M806855200","article-title":"Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction","volume":"284","author":"Hilgenberg","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib56","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.cell.2006.01.052","article-title":"Alpha3Na+\/K+-ATPase is a neuronal receptor for agrin","volume":"125","author":"Hilgenberg","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib57","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.bbabio.2016.08.009","article-title":"Neurological disease mutations of \u03b13 Na+,K+-ATPase: Structural and functional perspectives and rescue of compromised function","volume":"1857","author":"Holm","year":"2016","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep31972","article-title":"Cognitive deficits caused by a disease-mutation in the \u03b1 3 Na+\/K+-ATPase isoform","volume":"6","author":"Holm","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib59","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/epi.12878","article-title":"Knock-in mouse model of alternating hemiplegia of childhood: Behavioral and electrophysiologic characterization","volume":"56","author":"Hunanyan","year":"2015","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib60","first-page":"1","article-title":"Mechanisms of increased hippocampal excitability in the Mashl+\/- mouse model of Na+\/K+ -ATPase dysfunction","author":"Hunanyan","year":"2018","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib61","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1006763","article-title":"Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump","volume":"13","author":"Isaksen","year":"2017","journal-title":"PLoS Genet."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib62","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1096\/fj.05-5085fje","article-title":"Brain mitochondrial defects amplify intracellular [Ca2+] rise and neurodegeneration but not Ca2+ entry during NMDA receptor activation","volume":"20","author":"Jacquard","year":"2006","journal-title":"FASEB J"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib63","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nature12578","article-title":"Crystal structure of a Na + -bound Na +,K + -ATPase preceding the E1P state","volume":"502","author":"Kanai","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib64","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1038\/jcbfm.2014.104","article-title":"Highly energized inhibitory interneurons are a central element for information processing in cortical networks","volume":"34","author":"Kann","year":"2014","journal-title":"J. Cerebr. Blood Flow Metabol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib65","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1146\/annurev.biochem.71.102201.141218","article-title":"Biochemistry of Na,K-ATPase","volume":"71","author":"Kaplan","year":"2002","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib66","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1016\/j.celrep.2018.04.056","article-title":"Unconventional Secretion Mediates the Trans-cellular Spreading of Tau","volume":"23","author":"Katsinelos","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib67","doi-asserted-by":"crossref","first-page":"18144","DOI":"10.1073\/pnas.1108416108","article-title":"Mania-like behavior induced by genetic dysfunction of the neuron-specific Na + , K + -ATPase \u03b13 sodium pump","volume":"108","author":"Kirshenbaum","year":"2011","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib68","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.exer.2008.09.022","article-title":"Ankyrin-B is required for coordinated expression of beta-2-spectrin, the Na\/K-ATPase and the Na\/Ca exchanger in the inner segment of rod photoreceptors","volume":"88","author":"Kizhatil","year":"2009","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib69","doi-asserted-by":"crossref","first-page":"27015","DOI":"10.1074\/jbc.R115.689257","article-title":"The startling properties of fibroblast growth factor 2: How to exit mammalian cells without a signal peptide at hand","volume":"290","author":"La Venuta","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib70","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1002\/glia.22629","article-title":"Contributions of the Na+\/K+-ATPase, NKCC1, and Kir4.1 to hippocampal K+ clearance and volume responses","volume":"62","author":"Larsen","year":"2014","journal-title":"Glia"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib71","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1002129","article-title":"Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2","volume":"7","author":"Leo","year":"2011","journal-title":"PLoS Genet."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib72","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/j.neuron.2011.01.022","article-title":"Follistatin-like 1 suppresses sensory afferent transmission by activating Na+,K+-ATPase","volume":"69","author":"Li","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib73","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3389\/fcell.2015.00066","article-title":"Transcriptional regulators of Na,K-ATPase subunits","volume":"3","author":"Li","year":"2015","journal-title":"Front. cell Dev. Biol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib74","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/2192-2853-2-6","article-title":"Nanoscale elucidation of Na,K-ATPase isoforms in dendritic spines","volume":"2","author":"Liebmann","year":"2013","journal-title":"Opt. Nanoscopy"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib75","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.3390\/ijms19082214","article-title":"Regulation of Neuronal Na,K-ATPase by Extracellular Scaffolding Proteins","volume":"19","author":"Liebmann","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib76","doi-asserted-by":"crossref","first-page":"11461","DOI":"10.1074\/jbc.M706942200","article-title":"Ankyrin B modulates the function of Na,K-ATPase\/inositol 1,4,5-trisphosphate receptor signaling microdomain","volume":"283","author":"Liu","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib77","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s12311-011-0331-9","article-title":"Consensus paper: Roles of the cerebellum in motor control-the diversity of ideas on cerebellar involvement in movement","volume":"11","author":"Manto","year":"2012","journal-title":"Cerebellum"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib78","doi-asserted-by":"crossref","first-page":"7934","DOI":"10.1523\/JNEUROSCI.0635-05.2005","article-title":"MONaKA, a novel modulator of the plasma membrane Na,K-ATPase","volume":"25","author":"Mao","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib79","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1002\/cne.21160","article-title":"Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death","volume":"500","author":"Martin","year":"2007","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib80","article-title":"Early-onset encephalopathy with paroxysmal movement disorders and epileptic seizures without hemiplegic attacks: About three children with novel ATP1A3 mutations","volume":"1","author":"Marzin","year":"2018","journal-title":"Brain Dev."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib81","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1523\/JNEUROSCI.11-02-00381.1991","article-title":"Immunofluorescent localization of three Na,K-ATPase isozymes in the rat central nervous system: both neurons and glia can express more than one Na,K-ATPase","volume":"11","author":"McGrail","year":"1991","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib82","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.nbd.2017.03.011","article-title":"How the shapes of seeds can influence pathology","volume":"109","author":"Melki","year":"2018","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib83","series-title":"Disease-Modifying Targets in Neurodegenerative Disorders","first-page":"1","article-title":"The multitude of therapeutic targets in neurodegenerative proteinopathies","author":"Melki","year":"2017"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib84","doi-asserted-by":"crossref","first-page":"217","DOI":"10.3233\/JPD-150543","article-title":"Role of different alpha-synuclein strains in synucleinopathies, similarities with other neurodegenerative diseases","volume":"5","author":"Melki","year":"2015","journal-title":"J. Parkinson's Dis."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib85","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1523\/JNEUROSCI.4464-06.2007","article-title":"Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice","volume":"27","author":"Moseley","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib86","doi-asserted-by":"crossref","first-page":"16668","DOI":"10.1016\/S0021-9258(19)89442-5","article-title":"Tissue- and isoform-specific kinetic behavior of the Na,K-ATPase","volume":"269","author":"Munzer","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib87","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.braindev.2017.09.010","article-title":"A de novo p.Arg756Cys mutation in ATP1A3 causes a distinct phenotype with prolonged weakness and encephalopathy triggered by fever","volume":"40","author":"Nakamura","year":"2018","journal-title":"Brain Dev."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib88","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1046\/j.1471-4159.1999.0731492.x","article-title":"Regulation of Na+, K+-ATPase isoforms in rat neostriatum by dopamine and protein kinase C","volume":"73","author":"Nishi","year":"1999","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib89","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.1046\/j.1460-9568.1999.00724.x","article-title":"Requirement for DARPP-32 in mediating effect of dopamine D2 receptor activation","volume":"11","author":"Nishi","year":"1999","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib90","doi-asserted-by":"crossref","first-page":"E4465","DOI":"10.1073\/pnas.1421182112","article-title":"Na, K-ATPase \u03b13 is a death target of Alzheimer patient amyloid-\u03b2 assembly","volume":"112","author":"Ohnishi","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib91","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/epi.12914","article-title":"Novel mutations in ATP1A3 associated with catastrophic early life epilepsy, episodic prolonged apnea, and postnatal microcephaly","volume":"56","author":"Paciorkowski","year":"2015","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib92","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF00233390","article-title":"Lateral mobility of Na,K-ATPase and membrane lipids in renal cells. Importance of cytoskeletal integrity","volume":"142","author":"Paller","year":"1994","journal-title":"J. Membr. Biol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib93","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/0166-2236(93)90021-D","article-title":"Functions of agrin and agrin-related proteins","volume":"16","author":"Patthy","year":"1993","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib94","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1177\/0333102416651284","article-title":"Recurrent coma and fever in familial hemiplegic migraine type 2. A prospective 15-year follow-up of a large family with a novel ATP1A2 mutation","volume":"37","author":"Pelzer","year":"2017","journal-title":"Cephalalgia"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib95","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/(SICI)1098-1136(199811)24:3<257::AID-GLIA1>3.0.CO;2-#","article-title":"Plasticity of Na,K-ATPase isoform expression in cultures of flat astrocytes: species differences in gene expression","volume":"24","author":"Peng","year":"1998","journal-title":"Glia"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib96","doi-asserted-by":"crossref","first-page":"3488","DOI":"10.1523\/JNEUROSCI.17-10-03488.1997","article-title":"Isoforms of Na,K-ATPase alpha and beta subunits in the rat cerebellum and in granule cell cultures","volume":"17","author":"Peng","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib97","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.cell.2011.10.011","article-title":"The seeds of neurodegeneration: Prion-like spreading in ALS","volume":"147","author":"Polymenidou","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib98","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nature12975","article-title":"A polygenic burden of rare disruptive mutations in schizophrenia","volume":"506","author":"Purcell","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib99","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/nature20814","article-title":"Structural variation in amyloid-\u03b2 fibrils from Alzheimer's disease clinical subtypes","volume":"541","author":"Qiang","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib100","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.neuron.2010.04.029","article-title":"Deleterious Effects of Amyloid \u03b2 Oligomers Acting as an Extracellular Scaffold for mGluR5","volume":"66","author":"Renner","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib101","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1113\/jphysiol.2007.144733","article-title":"Differential expression of Na+\/K+-ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells","volume":"585","author":"Richards","year":"2007","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib102","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/cne.20401","article-title":"Target-determined expression of alpha3 isoform of the Na+,K+-ATPase in the somatic nervous system of rat","volume":"483","author":"Romanovsky","year":"2005","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib103","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1002\/cne.21218","article-title":"Phylogenetic preservation of alpha3 Na+,K+-ATPase distribution in vertebrate peripheral nervous systems","volume":"500","author":"Romanovsky","year":"2007","journal-title":"J. Comp. Neurol."},{"issue":"Pt 3","key":"10.1016\/j.neuropharm.2018.12.008_bib104","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1113\/jphysiol.1997.sp021951","article-title":"Regulation of intracellular sodium in cultured rat hippocampal neurones","volume":"499","author":"Rose","year":"1997","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib105","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1212\/WNL.0000000000000212","article-title":"The expanding clinical and genetic spectrum of ATP1A3-related disorders","volume":"82","author":"Rosewich","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib106","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s00401-015-1510-4","article-title":"Aberrant association of misfolded SOD1 with Na(+)\/K(+)ATPase-\u03b13 impairs its activity and contributes to motor neuron vulnerability in ALS","volume":"131","author":"Ruegsegger","year":"2016","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib107","article-title":"Childhood Rapid-Onset Ataxia: Expanding the Phenotypic Spectrum of ATP1A3 Mutations","volume":"1\u20135","author":"Schirinzi","year":"2018","journal-title":"Cerebellum"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib108","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1038\/nbt969","article-title":"Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues","volume":"22","author":"Schmitt-Ulms","year":"2004","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib109","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/nature07939","article-title":"Crystal structure of the sodium-potassium pump at 2.4 A resolution","volume":"459","author":"Shinoda","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib110","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.neuron.2017.05.026","article-title":"Physico-Pathologic Mechanisms Involved in Neurodegeneration: Misfolded Protein-Plasma Membrane Interactions","volume":"95","author":"Shrivastava","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib111","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1002\/glia.22548","article-title":"\u03b2-amyloid and ATP-induced diffusional trapping of astrocyte and neuronal metabotropic glutamate type-5 receptors","volume":"61","author":"Shrivastava","year":"2013","journal-title":"Glia"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib112","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.dib.2016.02.018","article-title":"Data in support of the identification of neuronal and astrocyte proteins interacting with extracellularly applied oligomeric and fibrillar \u03b1-synuclein assemblies by mass spectrometry","volume":"7","author":"Shrivastava","year":"2016","journal-title":"Data Br"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib113","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.15252\/embj.201591397","article-title":"\u03b1-synuclein assemblies sequester neuronal \u03b13-Na+\/K+-ATPase and impair Na+ gradient","volume":"34","author":"Shrivastava","year":"2015","journal-title":"EMBO J."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib137","doi-asserted-by":"crossref","DOI":"10.15252\/embj.201899871","article-title":"Clustering of tau fibrils impairs the synaptic composition of \u03b13-Na\u00b1\/K\u00b1-ATPase and AMPA receptors","author":"Shrivastava","year":"2019","journal-title":"EMBO J"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib114","doi-asserted-by":"crossref","first-page":"8034","DOI":"10.1073\/pnas.93.15.8034","article-title":"Dopamine inhibits mammalian photoreceptor Na+,K+-ATPase activity via a selective effect on the alpha3 isozyme","volume":"93","author":"Shulman","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib115","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0165-6147(00)01564-9","article-title":"Unraveling the function of GABA(A) receptor subtypes","volume":"21","author":"Sieghart","year":"2000","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib116","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.pediatrneurol.2017.12.009","article-title":"Fever-Induced Paroxysmal Weakness and Encephalopathy (FIPWE)-Part of a Phenotypic Continuum in Patients With ATP1A3 Mutations?","volume":"81","author":"Sival","year":"2018","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib117","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/0006-3002(57)90343-8","article-title":"The influence of some cations on an adenosine triphosphatase from peripheral nerves","volume":"23","author":"Skou","year":"1957","journal-title":"BBA - Biochim. Biophys. Acta"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib118","doi-asserted-by":"crossref","first-page":"a001008","DOI":"10.1101\/mcs.a001008","article-title":"A novel de novo mutation in ATP1A3 and childhood-onset schizophrenia","volume":"2","author":"Smedemark-Margulies","year":"2016","journal-title":"Cold Spring Harb. Mol. case Stud."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib119","doi-asserted-by":"crossref","first-page":"240","DOI":"10.4331\/wjbc.v5.i2.240","article-title":"Functional analysis of human Na(+)\/K(+)-ATPase familial or sporadic hemiplegic migraine mutations expressed in Xenopus oocytes","volume":"5","author":"Spiller","year":"2014","journal-title":"World J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib120","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1002\/glia.23194","article-title":"The \u03b12\u03b22 isoform combination dominates the astrocytic Na+\/K+-ATPase activity and is rendered nonfunctional by the \u03b12.G301R familial hemiplegic migraine type 2-associated mutation","volume":"65","author":"Stoica","year":"2017","journal-title":"Glia"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib121","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.neulet.2006.11.061","article-title":"Ouabain-induced isoform-specific localization change of the Na+, K+-ATPase alpha subunit in the synaptic plasma membrane of rat brain","volume":"413","author":"Taguchi","year":"2007","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib122","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.celrep.2017.12.074","article-title":"Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder","volume":"22","author":"Takata","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib123","doi-asserted-by":"crossref","first-page":"C619","DOI":"10.1152\/ajpcell.1990.259.4.C619","article-title":"Stability of Na(+)-K(+)-ATPase alpha-subunit isoforms in evolution","volume":"259","author":"Takeyasu","year":"1990","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib124","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.tibs.2010.05.004","article-title":"How are ion pumps and agrin signaling integrated?","volume":"35","author":"Tidow","year":"2010","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib125","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ymgmr.2018.06.001","article-title":"De novo ATP1A3 and compound heterozygous NLRP3 mutations in a child with autism spectrum disorder, episodic fatigue and somnolence, and muckle-wells syndrome","volume":"16","author":"Torres","year":"2018","journal-title":"Mol. Genet. Metab. reports"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib126","doi-asserted-by":"crossref","first-page":"3186","DOI":"10.1074\/jbc.M113.543272","article-title":"Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease","volume":"289","author":"Toustrup-Jensen","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib127","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1016\/j.str.2011.10.016","article-title":"First crystal structures of Na +,K +-ATPase: New light on the oldest ion pump","volume":"19","author":"Toyoshima","year":"2011","journal-title":"Structure"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib138","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.neuron.2008.06.022","article-title":"New concepts in synaptic biology derived from single-molecule imaging","volume":"59","author":"Triller","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib128","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0197659","article-title":"Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease","volume":"13","author":"Ulbrich","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.neuropharm.2018.12.008_bib129","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1111\/j.1742-4658.2008.06862.x","article-title":"A facile method for expression and purification of the Alzheimer's disease-associated amyloid beta-peptide","volume":"276","author":"Walsh","year":"2009","journal-title":"FEBS J."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib130","doi-asserted-by":"crossref","first-page":"17250","DOI":"10.1074\/jbc.M313239200","article-title":"Ouabain assembles signaling cascades through the caveolar Na+\/K+-ATPase","volume":"279","author":"Wang","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib131","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/9eb11869-6acb-49b0-978e-abedc3cc545a","article-title":"Interactome analyses identify ties of prpc and its mammalian paralogs to oligomannosidic n-glycans and endoplasmic reticulum-derived chaperones","volume":"5","author":"Watts","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib132","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.pediatrneurol.2017.04.022","article-title":"Fever-Induced Paroxysmal Weakness and Encephalopathy, a New Phenotype of ATP1A3 Mutation","volume":"73","author":"Yano","year":"2017","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib133","doi-asserted-by":"crossref","first-page":"3654","DOI":"10.1074\/jbc.M114.590067","article-title":"A Direct Role for ATP1A1 in Unconventional Secretion of Fibroblast Growth Factor 2","volume":"290","author":"Zacherl","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib134","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1085\/jgp.110.2.201","article-title":"Sodium kinetics of Na,K-ATPase alpha isoforms in intact transfected HeLa cells","volume":"110","author":"Zahler","year":"1997","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib135","doi-asserted-by":"crossref","first-page":"4498","DOI":"10.1523\/JNEUROSCI.6094-08.2009","article-title":"Na,K-ATPase activity regulates AMPA receptor turnover through proteasome-mediated proteolysis","volume":"29","author":"Zhang","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2018.12.008_bib136","doi-asserted-by":"crossref","first-page":"18681","DOI":"10.1074\/jbc.273.30.18681","article-title":"Structure of the ankyrin-binding domain of \u03b1-Na, K-ATPase","volume":"273","author":"Zhang","year":"1998","journal-title":"J. Biol. Chem."}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390818309079?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390818309079?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T06:59:55Z","timestamp":1758437995000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390818309079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":138,"alternative-id":["S0028390818309079"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2018.12.008","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cell biology and dynamics of Neuronal Na+\/K+-ATPase in health and diseases","name":"articletitle","label":"Article Title"},{"value":"Neuropharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuropharm.2018.12.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"107461"}}