{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T22:25:36Z","timestamp":1793917536827,"version":"4.8.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP22K06459"],"award-info":[{"award-number":["JP22K06459"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP25K09824"],"award-info":[{"award-number":["JP25K09824"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP22K19713"],"award-info":[{"award-number":["JP22K19713"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP24K02784"],"award-info":[{"award-number":["JP24K02784"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.neuropharm.2026.111144","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T05:55:01Z","timestamp":1785995701000},"page":"111144","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["M3 muscarinic receptor antagonism attenuates cocaine-induced hippocampal oligodendroglial changes and relapse-like behavior in male mice"],"prefix":"10.1016","volume":"300","author":[{"given":"Jun","family":"Yamada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichiro","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayumi","family":"Okamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoko M.","family":"Iinuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7596-8118","authenticated-orcid":false,"given":"Shozo","family":"Jinno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuropharm.2026.111144_bib1","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26157519","article-title":"Tabernanthalog, a non-hallucinogenic psychedelic, alleviates cancer-induced cognitive deficits via serotonergic pathways","volume":"26","author":"Arinaga","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib2","doi-asserted-by":"crossref","first-page":"329","DOI":"10.3389\/fnbeh.2018.00329","article-title":"The neurobiology of fear generalization","volume":"12","author":"Asok","year":"2018","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib3","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.drugalcdep.2017.08.003","article-title":"Glial and neuroinflammatory targets for treating substance use disorders","volume":"180","author":"Bachtell","year":"2017","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.neuropharm.2026.111144_bib4","doi-asserted-by":"crossref","first-page":"3745","DOI":"10.1007\/s00018-020-03498-8","article-title":"Molecular and circuit mechanisms regulating cocaine memory","volume":"77","author":"Bender","year":"2020","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib5","doi-asserted-by":"crossref","first-page":"11894","DOI":"10.1523\/JNEUROSCI.2397-17.2017","article-title":"Extinction of contextual cocaine memories requires Ca(v)1.2 within D1R-Expressing cells and recruits hippocampal Ca(v)1.2-Dependent signaling mechanisms","volume":"37","author":"Burgdorf","year":"2017","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib6","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1007\/s00213-006-0671-1","article-title":"Behavioral effects of morphine and cocaine in M1 muscarinic acetylcholine receptor-deficient mice","volume":"191","author":"Carrigan","year":"2007","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neuropharm.2026.111144_bib7","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/adb.12248","article-title":"Pharmacological reduction of adult hippocampal neurogenesis modifies functional brain circuits in mice exposed to a cocaine conditioned place preference paradigm","volume":"21","author":"Castilla-Ortega","year":"2016","journal-title":"Addict. Biol."},{"key":"10.1016\/j.neuropharm.2026.111144_bib8","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/B978-0-443-19102-2.00014-4","article-title":"Neuroglia in substance use disorders","volume":"210","author":"Castro","year":"2025","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/j.neuropharm.2026.111144_bib9","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1002\/dneu.20976","article-title":"Muscarinic receptor subtypes as potential targets to modulate oligodendrocyte progenitor survival, proliferation, and differentiation","volume":"72","author":"De Angelis","year":"2012","journal-title":"Dev. Neurobiol."},{"key":"10.1016\/j.neuropharm.2026.111144_bib10","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/nature12647","article-title":"A regenerative approach to the treatment of multiple sclerosis","volume":"502","author":"Deshmukh","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2026.111144_bib11","article-title":"Acetylcholine in the hippocampus: problems and achievements","volume":"19","author":"Dobryakova","year":"2025","journal-title":"Front. Neural Circ."},{"key":"10.1016\/j.neuropharm.2026.111144_bib12","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1474-8673.2006.00368.x","article-title":"Muscarinic receptor subtypes in neuronal and non-neuronal cholinergic function","volume":"26","author":"Eglen","year":"2006","journal-title":"Auton. Autacoid Pharmacol."},{"key":"10.1016\/j.neuropharm.2026.111144_bib13","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1038\/s41380-021-01256-1","article-title":"Molecular genetics of cocaine use disorders in humans","volume":"27","author":"Fern\u00e0ndez-Castillo","year":"2022","journal-title":"Mol. Psychiatr."},{"key":"10.1016\/j.neuropharm.2026.111144_bib14","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/nrn4023","article-title":"A new mechanism of nervous system plasticity: activity-dependent myelination","volume":"16","author":"Fields","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib15","doi-asserted-by":"crossref","first-page":"8305","DOI":"10.1523\/JNEUROSCI.0800-19.2019","article-title":"Epigenetic regulation of hippocampal fosb expression controls behavioral responses to cocaine","volume":"39","author":"Gajewski","year":"2019","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib16","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2208254119","article-title":"Spatial contextual recognition memory updating is modulated by dopamine release in the dorsal hippocampus from the locus coeruleus","volume":"119","author":"G\u00e1lvez-M\u00e1rquez","year":"2022","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2026.111144_bib17","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3390\/biomedicines8060153","article-title":"Possible correlation between cholinergic system alterations and neuro\/inflammation in multiple sclerosis","volume":"8","author":"Gatta","year":"2020","journal-title":"Biomedicines"},{"key":"10.1016\/j.neuropharm.2026.111144_bib18","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1038\/s41380-022-01833-y","article-title":"Whole-brain white matter abnormalities in human cocaine and heroin use disorders: association with craving, recency, and cumulative use","volume":"28","author":"Gaudreault","year":"2023","journal-title":"Mol. Psychiatr."},{"key":"10.1016\/j.neuropharm.2026.111144_bib19","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1365-2818.1977.tb00062.x","article-title":"Notes on the estimation of the numerical density of arbitrary profiles: the edge effect","volume":"111","author":"Gundersen","year":"1977","journal-title":"J. Microsc."},{"key":"10.1016\/j.neuropharm.2026.111144_bib20","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1365-2818.1987.tb02837.x","article-title":"The efficiency of systematic sampling in stereology and its prediction","volume":"147","author":"Gundersen","year":"1987","journal-title":"J. Microsc."},{"key":"10.1016\/j.neuropharm.2026.111144_bib21","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1111\/adb.12567","article-title":"Selective inhibition of M(5) muscarinic acetylcholine receptors attenuates cocaine self-administration in rats","volume":"23","author":"Gunter","year":"2018","journal-title":"Addict. Biol."},{"issue":"Suppl. 2","key":"10.1016\/j.neuropharm.2026.111144_bib22","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/jnc.14052","article-title":"Cholinergic modulation of the hippocampal region and memory function","volume":"142","author":"Haam","year":"2017","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neuropharm.2026.111144_bib23","doi-asserted-by":"crossref","first-page":"5270","DOI":"10.3390\/molecules28135270","article-title":"Are there prevalent sex differences in psychostimulant use disorder? A focus on the potential therapeutic efficacy of atypical dopamine uptake inhibitors","volume":"28","author":"Hersey","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.neuropharm.2026.111144_bib24","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1002\/hipo.22826","article-title":"Involvement of the dorsal hippocampus in expression and extinction of cocaine-induced conditioned place preference","volume":"28","author":"Hitchcock","year":"2018","journal-title":"Hippocampus"},{"key":"10.1016\/j.neuropharm.2026.111144_bib25","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1101\/lm.042374.116","article-title":"Behavioral mechanisms of context fear generalization in mice","volume":"23","author":"Huckleberry","year":"2016","journal-title":"Learn. Mem."},{"key":"10.1016\/j.neuropharm.2026.111144_bib26","doi-asserted-by":"crossref","first-page":"5300","DOI":"10.1523\/JNEUROSCI.2879-19.2020","article-title":"Genetic architecture and molecular neuropathology of human cocaine addiction","volume":"40","author":"Huggett","year":"2020","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib27","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0006-8993(98)01075-0","article-title":"Quantitative analysis of GABAergic neurons in the mouse hippocampus, with optical disector using confocal laser scanning microscope","volume":"814","author":"Jinno","year":"1998","journal-title":"Brain Res."},{"key":"10.1016\/j.neuropharm.2026.111144_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2023.105270","article-title":"Critical appraisal and systematic review of genes linked with cocaine addiction, depression and anxiety","volume":"152","author":"Kaushik","year":"2023","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neuropharm.2026.111144_bib29","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/npp.2016.174","article-title":"Sex differences in context fear generalization and recruitment of hippocampus and amygdala during retrieval","volume":"42","author":"Keiser","year":"2017","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuropharm.2026.111144_bib30","article-title":"Serotonin signaling in hippocampus during initial cocaine abstinence drives persistent drug seeking","volume":"44","author":"Kohtz","year":"2024","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib31","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1101\/lm.042192.116","article-title":"Effects of drugs of abuse on hippocampal plasticity and hippocampus-dependent learning and memory: contributions to development and maintenance of addiction","volume":"23","author":"Kutlu","year":"2016","journal-title":"Learn. Mem."},{"key":"10.1016\/j.neuropharm.2026.111144_bib32","doi-asserted-by":"crossref","first-page":"5293","DOI":"10.3390\/ijms25105293","article-title":"Dopamine pharmacodynamics: new insights","volume":"25","author":"Lauretani","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib33","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/sj.tpj.6500146","article-title":"Transcriptional profiling in the human prefrontal cortex: evidence for two activational states associated with cocaine abuse","volume":"3","author":"Lehrmann","year":"2003","journal-title":"Pharmacogenomics J."},{"key":"10.1016\/j.neuropharm.2026.111144_bib34","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1002\/glia.24513","article-title":"Transient demyelination causes long-term cognitive impairment, myelin alteration and network synchrony defects","volume":"72","author":"Mercier","year":"2024","journal-title":"Glia"},{"key":"10.1016\/j.neuropharm.2026.111144_bib35","doi-asserted-by":"crossref","first-page":"5928","DOI":"10.1007\/s12035-024-03950-x","article-title":"Bioenergetics of axon integrity and its regulation by oligodendrocytes and schwann cells","volume":"61","author":"Mishra","year":"2024","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.neuropharm.2026.111144_bib36","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.pscychresns.2014.01.005","article-title":"Chronic cocaine administration causes extensive white matter damage in brain: diffusion tensor imaging and immunohistochemistry studies","volume":"221","author":"Narayana","year":"2014","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.neuropharm.2026.111144_bib37","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1151\/spp05314","article-title":"The neurobiology of cocaine addiction","volume":"3","author":"Nestler","year":"2005","journal-title":"Sci Pract Perspect"},{"key":"10.1016\/j.neuropharm.2026.111144_bib38","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1038\/s41593-024-01642-2","article-title":"Dynamics of mature myelin","volume":"27","author":"Osso","year":"2024","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib39","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2407974121","article-title":"Targeting the muscarinic M1 receptor with a selective, brain-penetrant antagonist to promote remyelination in multiple sclerosis","volume":"121","author":"Poon","year":"2024","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2026.111144_bib40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0237451","article-title":"Blockade of the M1 muscarinic acetylcholine receptors impairs eyeblink serial feature-positive discrimination learning in mice","volume":"15","author":"Rahman","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.neuropharm.2026.111144_bib41","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.bbr.2012.03.030","article-title":"Biperiden (M1 antagonist) impairs the expression of cocaine conditioned place preference but potentiates the expression of cocaine-induced behavioral sensitization","volume":"231","author":"Ramos","year":"2012","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuropharm.2026.111144_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2023.114841","article-title":"Biperiden reverses the increase in 50-kHz ultrasonic vocalizations but not the increase in locomotor activity induced by cocaine","volume":"461","author":"Saldanha","year":"2024","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuropharm.2026.111144_bib43","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.54950","article-title":"Mindfulness training vs recovery support for opioid use, craving, and anxiety during buprenorphine treatment: a randomized clinical trial","volume":"8","author":"Schuman-Olivier","year":"2025","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.neuropharm.2026.111144_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2024.105721","article-title":"Behaviorally conditioned effects of psychoactive drugs in experimental animals: what we have learned from nearly a century of research and what remains to be learned","volume":"162","author":"Schwarting","year":"2024","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neuropharm.2026.111144_bib45","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1124\/mol.109.056531","article-title":"A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning","volume":"76","author":"Sheffler","year":"2009","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.neuropharm.2026.111144_bib46","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.2174\/1570159X17666190617101726","article-title":"Cocaine-induced changes in the expression of NMDA receptor subunits","volume":"17","author":"Smaga","year":"2019","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.neuropharm.2026.111144_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2022.116068","article-title":"Chronic escalating-dose and acute binge cocaine treatments change the hippocampal cholinergic muscarinic system on drug presence and after withdrawal","volume":"447","author":"Spelta","year":"2022","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.neuropharm.2026.111144_bib48","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1038\/nrn3785","article-title":"Functional organization of the hippocampal longitudinal axis","volume":"15","author":"Strange","year":"2014","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib49","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1124\/jpet.109.162057","article-title":"Attenuation of cocaine's reinforcing and discriminative stimulus effects via muscarinic M1 acetylcholine receptor stimulation","volume":"332","author":"Thomsen","year":"2010","journal-title":"J. Pharmacol. Exp. Therapeut."},{"key":"10.1016\/j.neuropharm.2026.111144_bib50","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1038\/s41573-024-01007-1","article-title":"A golden age of muscarinic acetylcholine receptor modulation in neurological diseases","volume":"23","author":"Tobin","year":"2024","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.neuropharm.2026.111144_bib51","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1038\/s41398-021-01367-x","article-title":"White matter deficits in cocaine use disorder: convergent evidence from in vivo diffusion tensor imaging and ex vivo proteomic analysis","volume":"11","author":"Tondo","year":"2021","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.neuropharm.2026.111144_bib52","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.2174\/156802609789753635","article-title":"Discovery and development of a potent and highly selective small molecule muscarinic acetylcholine receptor subtype I (mAChR 1 or M1) antagonist in vitro and in vivo probe","volume":"9","author":"Weaver","year":"2009","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.neuropharm.2026.111144_bib53","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1038\/s41386-020-0684-1","article-title":"Effects of muscarinic M(1) receptor stimulation on reinforcing and neurochemical effects of cocaine in rats","volume":"45","author":"Weikop","year":"2020","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuropharm.2026.111144_bib54","doi-asserted-by":"crossref","first-page":"6921","DOI":"10.1523\/JNEUROSCI.1862-17.2018","article-title":"Muscarinic receptor M(3)R signaling prevents efficient remyelination by human and mouse oligodendrocyte progenitor cells","volume":"38","author":"Welliver","year":"2018","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib55","doi-asserted-by":"crossref","first-page":"26460","DOI":"10.1073\/pnas.2006133117","article-title":"Neuroadaptations in the dorsal hippocampus underlie cocaine seeking during prolonged abstinence","volume":"117","author":"Werner","year":"2020","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.neuropharm.2026.111144_bib56","doi-asserted-by":"crossref","first-page":"5552","DOI":"10.1523\/JNEUROSCI.0645-22.2022","article-title":"Muscarinic acetylcholine M(2) receptors regulate lateral habenula neuron activity and control cocaine seeking behavior","volume":"42","author":"Wolfe","year":"2022","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuropharm.2026.111144_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.jchemneu.2023.102375","article-title":"Solifenacin promotes remyelination in cuprizone mouse model by inhibiting the Wnt\/\u03b2-catenin signaling pathway","volume":"136","author":"Xu","year":"2024","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.neuropharm.2026.111144_bib58","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1038\/s41586-024-07525-7","article-title":"Myelin plasticity in the ventral tegmental area is required for opioid reward","volume":"630","author":"Yal\u00e7\u0131n","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.neuropharm.2026.111144_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2022.109093","article-title":"Alleviation of cognitive deficits via upregulation of chondroitin sulfate biosynthesis by lignan sesamin in a mouse model of neuroinflammation","volume":"108","author":"Yamada","year":"2022","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.neuropharm.2026.111144_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2024.115097","article-title":"miR-181a expressed in the dorsal hippocampus regulates the reinstatement of cocaine CPP by targeting PRKAA1","volume":"471","author":"Zhu","year":"2024","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuropharm.2026.111144_bib61","doi-asserted-by":"crossref","first-page":"3381","DOI":"10.1038\/s41467-025-57339-y","article-title":"Cell type-specific multi-omics analysis of cocaine use disorder in the human caudate nucleus","volume":"16","author":"Zillich","year":"2025","journal-title":"Nat. Commun."}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390826003199?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390826003199?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T21:50:01Z","timestamp":1793915401000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390826003199"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":61,"alternative-id":["S0028390826003199"],"URL":"https:\/\/doi.org\/10.1016\/j.neuropharm.2026.111144","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"M3 muscarinic receptor antagonism attenuates cocaine-induced hippocampal oligodendroglial changes and relapse-like behavior in male mice","name":"articletitle","label":"Article Title"},{"value":"Neuropharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuropharm.2026.111144","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"111144"}}