{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T14:19:18Z","timestamp":1791555558516,"version":"4.3.4"},"reference-count":54,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2004,1]]},"DOI":"10.1016\/j.neuroscience.2004.03.049","type":"journal-article","created":{"date-parts":[[2004,5,8]],"date-time":"2004-05-08T11:37:11Z","timestamp":1084016231000},"page":"391-403","source":"Crossref","is-referenced-by-count":31,"title":["Axon terminals possessing \u03b12C-adrenergic receptors densely innervate neurons in the rat lateral spinal nucleus which respond to noxious stimulation"],"prefix":"10.1016","volume":"126","author":[{"given":"M.J.","family":"Olave","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.J.","family":"Maxwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2004.03.049_BIB1","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1073\/pnas.96.1.260","article-title":"Neurons in the dorsal column white matter of the spinal cord","volume":"96","author":"Abbadie","year":"1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/0361-9230(80)90184-7","article-title":"Acetylcholinesterase and catecholamine distribution in the locus ceruleus of the rat","volume":"5","author":"Albanese","year":"1980","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB3","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1002\/cne.902290305","article-title":"The morphology and distribution of neurons containing choline acetyltransferase in the adult rat spinal cord","volume":"229","author":"Barber","year":"1984","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB4","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/0006-8993(86)91407-1","article-title":"Topography of choline acetyltransferase immunoreactivity neurons and fibres in the rat spinal cord","volume":"362","author":"Borges","year":"1986","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB5","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1002\/cne.902290405","article-title":"A comparison of the ultrastructure of substance P and enkephalin-immunoreactive elements in the nucleus of the dorsal lateral funiculus and laminae I and II of the rat spinal cord","volume":"229","author":"Bresnahan","year":"1984","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB6","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1002\/cne.902910302","article-title":"Cells of origin of the spinohypothalamic tract in the rat","volume":"291","author":"Burstein","year":"1990","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB7","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/0006-8993(88)90381-2","article-title":"Studies of peptidergic input to the lateral spinal nucleus","volume":"460","author":"Cliffer","year":"1988","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB8","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/cne.10873","article-title":"A comparative reappraisal of projections from the superficial laminae of the dorsal horn in the rat","volume":"468","author":"Gauriau","year":"2004","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB9","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1523\/JNEUROSCI.05-07-01833.1985","article-title":"Immunocytochemical studies of the peptidergic of fibers and terminals within the lateral spinal and lateral cervical nuclei","volume":"5","author":"Giesler","year":"1985","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB10","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/cne.901840107","article-title":"Differential origins of spinothalamic tract projections to medial and lateral thalamus in the rat","volume":"184","author":"Giesler","year":"1979","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB11","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/cne.901860105","article-title":"Response properties of neurons of the lateral cervical nucleus in the rat","volume":"186","author":"Giesler","year":"1979","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB12","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/BF00712800","article-title":"A noncholinergic action of acetylcholinesterase (AChE) in the brain","volume":"11","author":"Greenfield","year":"1991","journal-title":"Cell Mol Neurobiol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB13","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1113\/jphysiol.2001.012890","article-title":"Correlations between neuronal morphology and electrophysiological features in the rodent superficial dorsal horn","volume":"540","author":"Grudt","year":"2002","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB14","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/0006-8993(68)90204-7","article-title":"A nucleus in the dorsal lateral funiculus of the spinal cord of the rat","volume":"10","author":"Gwyn","year":"1968","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB15","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/cne.901360208","article-title":"Observations on the morphology of a nucleus in the dorsolateral funiculus of the spinal cord of the guinea-pig, rabbit, ferret and cat","volume":"136","author":"Gwyn","year":"1969","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB16","doi-asserted-by":"crossref","first-page":"3081","DOI":"10.1073\/pnas.74.7.3081","article-title":"Immunohistochemical analysis of peptide pathways possibly related to pain and analgesia","volume":"74","author":"H\u00f6kfelt","year":"1977","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB17","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1038\/328632a0","article-title":"Induction of c-Fos-like protein in spinal cord neurons following sensory stimulation","volume":"328","author":"Hunt","year":"1987","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB18","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0006-8993(78)90146-4","article-title":"Capsaicin induced depletion of SP from primary sensory neurons","volume":"152","author":"Jessel","year":"1978","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB19","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/cne.902150409","article-title":"Collaterals of spinothalamic cells in the rat","volume":"215","author":"Kevetter","year":"1983","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB20","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1002\/cne.903110409","article-title":"Central projections of the sciatic, saphenous, median, and ulnar nerves of the rat demonstrated by transganglionic transport of choleragenoid-HRP (B-HRP) and wheat germ agglutinin-HRP (WGA-HRP)","volume":"311","author":"LaMotte","year":"1991","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB21","series-title":"Advances in pain research and therapy, Vol. 5","first-page":"277","article-title":"Substance P in the dorsal horns of partially deafferented rats","author":"Larabi","year":"1983"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB22","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0306-4522(88)90323-5","article-title":"Neuropeptides in long ascending spinal tract cells in the rat","volume":"24","author":"Leah","year":"1988","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB23","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1002\/cne.10619","article-title":"Central projection of unmyelinated (C) primary afferent fibers from gastrocnemius muscle in the guinea pig","volume":"461","author":"Ling","year":"2003","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB24","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/0306-4522(96)00366-1","article-title":"A confocal microscope survey of serotoninergic axons in the lumbar spinal cord of the rat","volume":"75","author":"Maxwell","year":"1996","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB25","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1002\/cne.902550310","article-title":"Spinal and trigeminal projections to the nucleus of the solitary tract","volume":"255","author":"Men\u00e9trey","year":"1987","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB26","series-title":"Spinal cord sensation","first-page":"179","article-title":"Elecrophysiology and location of dorsal horn neurons in the rat, including cells at the origin of the spinoreticular and spinothalamic tracts","author":"Men\u00e9trey","year":"1981"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB27","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1152\/jn.1980.44.5.862","article-title":"Location and properties of dorsal horn neurons at origin of spinoreticular tract in lumbar enlargement of the rat","volume":"44","author":"Men\u00e9trey","year":"1980","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB28","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/cne.902060208","article-title":"The origin of the spinopmesencephalic tract in the rat","volume":"206","author":"Men\u00e9trey","year":"1982","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB28A","series-title":"Cytochemical methods in neuroanatomy","first-page":"297","article-title":"The immunocytochemical demonstration of GABAergic neurons\u2014methods and application","author":"Oertel","year":"1982"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB29","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0306-4522(02)00407-4","article-title":"An investigation of neurons that possess the \u03b12c-adrenergic receptor in the rat dorsal horn","volume":"115","author":"Olave","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB30","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0006-8993(02)04124-0","article-title":"Axon terminals possessing the \u03b12c-adrenergic receptor in the rat dorsal horn are predominantly excitatory","volume":"965","author":"Olave","year":"2003","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB30A","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"1997"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB31","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/0006-8993(86)90429-4","article-title":"Spinal neurons which project to the periaqueductal gray and the medullary reticular formation via axon collaterals","volume":"374","author":"Pechura","year":"1986","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB32","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1002\/(SICI)1096-9861(20000626)422:2<312::AID-CNE11>3.0.CO;2-A","article-title":"Propriospinal afferent and efferent connections of the lateral and medial areas of the dorsal horn (laminae I\u2013IV) in the rat lumbar spinal cord","volume":"422","author":"Petk\u00f3","year":"2000","journal-title":"J Comp Nerol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB33","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/cne.903270210","article-title":"Immunocytochemical study of somatostatin, neurotensin, GABA, and glycine in rat spinal dorsal horn","volume":"327","author":"Proudlock","year":"1992","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB34","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/0304-3940(92)90216-T","article-title":"Demonstration of transganglionically transported choleragenoid in rat spinal cord by immunofluorescence cytochemistry","volume":"145","author":"Rivero-Melian","year":"1992","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB35","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/0306-4522(93)90218-5","article-title":"Evidence that neuropeptide Y is present in GABAergic neurons in the superficial dorsal horn of the rat spinal cord","volume":"53","author":"Rowan","year":"1993","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB36","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1177\/28.4.6154731","article-title":"Immunohistochemical studies of peptidergic neurons in the dorsal horn of the spinal cord","volume":"28","author":"Seybold","year":"1980","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB37","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/0006-8993(94)90268-2","article-title":"A cholinergic propriospinal innervation of the rat spinal cord","volume":"634","author":"Sheriff","year":"1994","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB38","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1007\/BF01188046","article-title":"Selective neuronal glycoconjugate expression in sensory and autonomic ganglia","volume":"19","author":"Silverman","year":"1990","journal-title":"J Neurocytol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB39","doi-asserted-by":"crossref","first-page":"5928","DOI":"10.1523\/JNEUROSCI.18-15-05928.1998","article-title":"Differential distribution of alpha2A and alpha2C adrenergic receptor immunoreactivity in the rat spinal cord","volume":"18","author":"Stone","year":"1998","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB40","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1152\/jn.1989.62.4.834","article-title":"Difference in distribution of central terminals between visceral and somatic unmyelinated (C) primary afferent fibers","volume":"62","author":"Sugiura","year":"1989","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB41","first-page":"1319","article-title":"Superficial NK1-expressing neurons control spinal excitability through activation of descending pathways","volume":"5","author":"Suzuki","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB42","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/35025070","article-title":"Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons","volume":"407","author":"Takamori","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB43","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1046\/j.1460-9568.2003.02406.x","article-title":"The expression of vesicular glutamate transporters VGLUT1 and VGLUT2 in neurochemically defined axonal populations in the rat spinal cord with emphasis on the dorsal horn","volume":"17","author":"Todd","year":"2003","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB44","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1046\/j.1460-9568.2000.00950.x","article-title":"Neurokinin 1 receptor expression by neurons in laminae I, III and IV of the rat spinal dorsal horn that project to the brainstem","volume":"12","author":"Todd","year":"2000","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB45","doi-asserted-by":"crossref","first-page":"4103","DOI":"10.1523\/JNEUROSCI.22-10-04103.2002","article-title":"Projection neurons in lamina I of rat spinal cord with the neurokinin 1 receptor are selectively innervated by substance P-containing afferents and respond to noxious stimulation","volume":"22","author":"Todd","year":"2002","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB46","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/0306-4522(92)90176-3","article-title":"Immunocytochemical evidence that GABA and neurotensin exist in different neurons in laminae II and III of rat spinal dorsal horn","volume":"47","author":"Todd","year":"1992","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB47","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/0301-0082(93)90045-T","article-title":"The localization of classical transmitters and neuropeptides within neurons in laminae I\u2013III of the mammalian spinal dorsal horn","volume":"41","author":"Todd","year":"1993","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB48","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/0306-4522(94)90525-8","article-title":"Some inhibitory neurons in the spinal cord develop c-fos-immunoreactivity after noxious stimulation","volume":"63","author":"Todd","year":"1994","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB49","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1523\/JNEUROSCI.14-02-00774.1994","article-title":"Immunocytochemical evidence that neurotensin is present in glutamatergic neurons in the superficial dorsal horn of the rat","volume":"14","author":"Todd","year":"1994","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB50","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/207642a0","article-title":"Characteristics of excitatory and inhibitory synapses in the central nervous system of the cat","volume":"207","author":"Uchizono","year":"1965","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB51","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1523\/JNEUROSCI.22-01-00142.2002","article-title":"Identification of the differentiation-associated Na+\/PI transporter as a novel vesicular glutamate transporter expressed in a distinct set of glutamatergic synapses","volume":"22","author":"Varoqui","year":"2002","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2004.03.049_BIB52","doi-asserted-by":"crossref","first-page":"3952","DOI":"10.1523\/JNEUROSCI.15-05-03952.1995","article-title":"Glycine transporters are differentially expressed among CNS cells","volume":"15","author":"Zafra","year":"1995","journal-title":"J Neurosci"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452204002350?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452204002350?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,9]],"date-time":"2019-02-09T16:27:27Z","timestamp":1549729647000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452204002350"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1]]},"references-count":54,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,1]]}},"alternative-id":["S0306452204002350"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2004.03.049","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2004,1]]}}}