{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T14:40:48Z","timestamp":1742395248594},"reference-count":49,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2004,1]]},"DOI":"10.1016\/j.neuroscience.2004.04.062","type":"journal-article","created":{"date-parts":[[2004,7,28]],"date-time":"2004-07-28T14:40:09Z","timestamp":1091025609000},"page":"753-767","source":"Crossref","is-referenced-by-count":10,"title":["Non-angiotensin II [125I] CGP42112 binding is a sensitive marker of neuronal injury in brainstem following unilateral nodose ganglionectomy: Comparison with markers for activated microglia"],"prefix":"10.1016","volume":"127","author":[{"given":"C.L","family":"Roulston","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.J","family":"Lawrence","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Jarrott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.E","family":"Widdop","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2004.04.062_BIB1","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0014-4886(05)80024-X","article-title":"Systemic injection of kainic acid","volume":"109","author":"Altar","year":"1990","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB2","series-title":"Human cytokines","author":"Aggarwal","year":"1992"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB3","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/S0306-4522(97)00476-4","article-title":"Nicotinic acetylcholine receptors in the rat and primate nucleus tractus solitarius and on rat and human inferior vagal (nodose) ganglia","volume":"83","author":"Ashworth-Preece","year":"1998","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB4","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1097\/00004647-200106000-00006","article-title":"Neuroprotection in ischemia-reperfusion injury","volume":"21","author":"Beech","year":"2001","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB5","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1177\/25.6.69656","article-title":"Specificity of the glial fibrillary acidic protein for astroglia","volume":"25","author":"Bignami","year":"1977","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB6","series-title":"Glial cells in the central nervous system and their reaction to injury","author":"Bignami","year":"1994"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB7","first-page":"1129","article-title":"Selective peptide and nonpeptide ligands differentially bind to angiotensin II AT2 receptor and a non-angiotensin II CGP42112 binding site","volume":"274","author":"Ciuffo","year":"1995","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB8","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3181\/00379727-210-43927AA","article-title":"Nitric oxide","volume":"210","author":"Clancy","year":"1995","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB9","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/j.1476-5381.1994.tb16174.x","article-title":"The involvement of bradykinin B1 and B2 receptor mechanisms in cytokine-induced mechanical hyperalgesia in the rat","volume":"113","author":"Davis","year":"1994","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB10","first-page":"415","article-title":"International Union of Pharmacology: XXIII","volume":"52","author":"de Gasparo","year":"2000","journal-title":"The angiotensin receptors. Pharmacol Rev"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB11","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1006\/bbrc.1994.1556","article-title":"Specific, non-angiotensin, [125I]CGP 42112 binding sites in rat spleen macrophages","volume":"200","author":"de Oliveira","year":"1994","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB12","first-page":"409","article-title":"The heterogeneity of mononuclear phagocytes in lymphoid organs","volume":"186","author":"Dijkstra","year":"1985","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB13","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/0361-9230(86)90217-0","article-title":"Contribution of the vagus nerve to angiotensin II binding sites in the canine medulla","volume":"17","author":"Diz","year":"1986","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB14","doi-asserted-by":"crossref","first-page":"C826","DOI":"10.1152\/ajpcell.1997.273.3.C826","article-title":"CGP-42112 partially activates human monocytes and reduces their stimulation by lipopolysaccharides","volume":"273","author":"Egidy","year":"1997","journal-title":"Am J Physiol"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB15","first-page":"S27","article-title":"Bradykinin and neuronal injury","volume":"9","author":"Francel","year":"1992","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB15A","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/S0197-0186(97)00007-7","article-title":"Increased expression of peripheral benzodiazepine receptors in the facial nucleus following motor neuron axotomy","volume":"31","author":"Gehlert","year":"1997","journal-title":"Neurochem Int"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB16","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1677\/jme.0.0310359","article-title":"The angiotensin type 2 receptor of angiotensin II and neuronal differentiation","volume":"31","author":"Gendron","year":"2003","journal-title":"J Mol Endocrinol"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB17","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1002\/glia.440070116","article-title":"Reactive glia as rivals in regulating neuronal survival","volume":"7","author":"Giulian","year":"1993","journal-title":"Glia"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0006-8993(89)90343-0","article-title":"Quantitative autoradiography of angiotensin II receptors in the rat solitary-vagal area","volume":"484","author":"Healy","year":"1989","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB19","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0006-8993(95)00092-5","article-title":"Quantitative autoradiography of angiotensin II AT2 receptors with [125I]CGP 42112","volume":"677","author":"Heemskerk","year":"1995","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB20","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1097\/00001756-199301000-00027","article-title":"Characterisation of brain angiotensin II AT2 receptor subtype using [125I] CGP 42112A","volume":"4","author":"Heemskerk","year":"1993","journal-title":"Neuroreport"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB21","doi-asserted-by":"crossref","first-page":"11952","DOI":"10.1074\/jbc.272.18.11952","article-title":"Interferon regulatory factor-1 up-regulates angiotensin II type 2 receptor and induces apoptosis","volume":"272","author":"Horiuchi","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB22","series-title":"Cerebral ischemia: molecular and cellular pathophysiology","first-page":"233","article-title":"Reactive astrogliosis in the injured and postischemic brain","author":"Jabs","year":"1999"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB23","series-title":"Cerebral ischemia: molecular and cellular pathophysiology","first-page":"251","article-title":"Activated and phagocytic microglia","author":"Kondo","year":"1999"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB24","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/0166-2236(96)10049-7","article-title":"Microglia","volume":"19","author":"Kreutzberg","year":"1996","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB25","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1111\/j.1476-5381.1995.tb13352.x","article-title":"Functional dopamine D2 receptors on rat vagal afferent neurones","volume":"114","author":"Lawrence","year":"1995","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB26","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/0014-2999(86)90043-9","article-title":"Angiotensin II receptor binding in the rat nucleus tractus solitarii is reduced after unilateral nodose ganglionectomy or vagotomy","volume":"125","author":"Lewis","year":"1986","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB27","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1084\/jem.188.4.661","article-title":"The angiotensin II type 2 receptor promotes axonal regeneration in the optic nerve of adult rats","volume":"188","author":"Lucius","year":"1998","journal-title":"J Exp Med"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB28","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/S0306-4522(99)00015-9","article-title":"Hypotension activates neuropeptide Y-containing neurons in the rat medulla oblongata","volume":"92","author":"McLean","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB29","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/0304-3940(87)90408-3","article-title":"The use of 14C-labeled tissue paste standards for the calibration of 125I-labeled ligands in quantitative autoradiography","volume":"81","author":"Miller","year":"1987","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB30","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"1986"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB30A","first-page":"177","article-title":"Modulation of microglia phenotype","volume":"20","author":"Perry","year":"1994","journal-title":"Neuropath Appl Neurobiol"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB31","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1440-1681.1990.tb01328.x","article-title":"Reduced V1 vasopressin binding in the rat nucleus solitarii after nodose ganglionectomy","volume":"17","author":"Phillips","year":"1990","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB32","first-page":"239","article-title":"Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3","volume":"57","author":"Robinson","year":"1986","journal-title":"Immunology"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB33","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0006-8993(03)02231-5","article-title":"Localization of AT2 receptors in the nucleus of the solitary tract of spontaneously hypertensive and Wistar Kyoto rats using [125I] CGP42112","volume":"968","author":"Roulston","year":"2003","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB34","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1007\/s000180050074","article-title":"Regulation of cyclooxygenase enzymes by nitric oxide","volume":"53","author":"Salvemini","year":"1997","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB35","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/0196-9781(87)90043-X","article-title":"Nodose ganglionectomy reduces angiotensin II receptor binding in the rat brainstem","volume":"8","author":"Speth","year":"1987","journal-title":"Peptides"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB36","doi-asserted-by":"crossref","first-page":"5263","DOI":"10.1523\/JNEUROSCI.15-07-05263.1995","article-title":"Peripheral benzodiazepine receptors are colocalized with activated microglia following transient global forebrain ischemia in the rat","volume":"15","author":"Stephenson","year":"1995","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB37","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0301-0082(98)00069-0","article-title":"Reactive microgliosis","volume":"57","author":"Streit","year":"1999","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB38","doi-asserted-by":"crossref","first-page":"7527","DOI":"10.4049\/jimmunol.166.12.7527","article-title":"Minocycline provides neuroprotection against N-methyl-d-aspartate neurotoxicity by inhibiting microglia","volume":"166","author":"Tikka","year":"2001","journal-title":"J Immunol"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB39","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1006\/bbrc.1999.0798","article-title":"Regulation by interleukin-1beta of gene expression of bradykinin B1 receptor in MH-S murine alveolar macrophage cell line","volume":"259","author":"Tsukagoshi","year":"1999","journal-title":"Biochem Biophys Res Comm"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB40","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF02088592","article-title":"[125I]CGP 42112 reveals a non-angiotensin II binding site in 1-methyl-4-phenylpyridine (MPP+)-induced brain injury","volume":"14","author":"Viswanathan","year":"1994","journal-title":"Cell Mol Neurobiol"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB41","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0006-8993(09)90035-X","article-title":"Expression of a novel non-angiotensin II [125I]CGP 42112 binding site in healing wounds of the rat brain","volume":"658","author":"Viswanathan","year":"1994","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB42","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/0196-9781(96)00064-2","article-title":"Increased non-angiotensin II [125I]CGP 42112 binding in rat carotid artery after balloon injury","volume":"17","author":"Viswanathan","year":"1996","journal-title":"Peptides"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB43","series-title":"Receptor autoradiography principles and practice","author":"Wharton","year":"1993"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB44","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s004410051311","article-title":"Detection of endogenous biotin in various tissues","volume":"296","author":"Wang","year":"1999","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB45","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1016\/0006-291X(91)92089-3","article-title":"Radioiodinated CGP 42112A","volume":"181","author":"Whitebread","year":"1991","journal-title":"Biochem Biophys Res Comm"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB46","doi-asserted-by":"crossref","first-page":"15769","DOI":"10.1073\/pnas.95.26.15769","article-title":"Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia","volume":"95","author":"Yrj\u00e4nheikki","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.neuroscience.2004.04.062_BIB47","doi-asserted-by":"crossref","first-page":"13496","DOI":"10.1073\/pnas.96.23.13496","article-title":"A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window","volume":"96","author":"Yrj\u00e4nheikki","year":"1999","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452204004051?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452204004051?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,5]],"date-time":"2019-02-05T10:24:39Z","timestamp":1549362279000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452204004051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,1]]}},"alternative-id":["S0306452204004051"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2004.04.062","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2004,1]]}}}