{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:27:40Z","timestamp":1793305660144,"version":"4.5.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.neuroscience.2005.12.037","type":"journal-article","created":{"date-parts":[[2006,2,8]],"date-time":"2006-02-08T18:25:05Z","timestamp":1139423105000},"page":"813-820","source":"Crossref","is-referenced-by-count":173,"title":["Sucrose sham feeding on a binge schedule releases accumbens dopamine repeatedly and eliminates the acetylcholine satiety response"],"prefix":"10.1016","volume":"139","author":[{"given":"N.M.","family":"Avena","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Rada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Moise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.G.","family":"Hoebel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2005.12.037_bib1","series-title":"Diagnostic and statistical manual of the American Psychological Association IV","year":"1994"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.alcohol.2004.09.006","article-title":"Sugar-dependent rats show enhanced intake of unsweetened ethanol","volume":"34","author":"Avena","year":"2004","journal-title":"Alcohol"},{"issue":"3","key":"10.1016\/j.neuroscience.2005.12.037_bib3","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.physbeh.2004.12.016","article-title":"Sugar-dependent rats show enhanced responding for sugar after abstinence","volume":"84","author":"Avena","year":"2005","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib4","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0306-4522(03)00502-5","article-title":"A diet promoting sugar dependency causes behavioral cross-sensitization to a low dose of amphetamine","volume":"122","author":"Avena","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib5","doi-asserted-by":"crossref","first-page":"4389","DOI":"10.1046\/j.1460-9568.1999.00843.x","article-title":"Modulation of feeding-induced activation of mesolimbic dopamine transmission by appetitive stimuli and its relation to motivational state","volume":"11","author":"Bassareo","year":"1999","journal-title":"Eur J Neurosci"},{"issue":"4","key":"10.1016\/j.neuroscience.2005.12.037_bib6","first-page":"E280","article-title":"Sham feeding-induced cephalic phase insulin release in the rat","volume":"242","author":"Berthoud","year":"1982","journal-title":"Am J Physiol"},{"issue":"2","key":"10.1016\/j.neuroscience.2005.12.037_bib7","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.conb.2004.03.004","article-title":"Neural and psychological mechanisms underlying appetitive learning","volume":"14","author":"Cardinal","year":"2004","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib8","doi-asserted-by":"crossref","first-page":"3549","DOI":"10.1097\/00001756-200111160-00035","article-title":"Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain","volume":"12","author":"Colantuoni","year":"2001","journal-title":"Neuroreport"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib9","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1038\/oby.2002.66","article-title":"Evidence that intermittent, excessive sugar intake causes endogenous opioid dependence","volume":"10","author":"Colantuoni","year":"2002","journal-title":"Obes Res"},{"issue":"1\u20132","key":"10.1016\/j.neuroscience.2005.12.037_bib10","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.physbeh.2005.07.020","article-title":"Baclofen reduces fat intake under binge-type conditions","volume":"86","author":"Buda-Levin","year":"2005","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib11","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s002130050465","article-title":"Blunting of reactivity of dopamine transmission to palatable food","volume":"134","author":"Di Chiara","year":"1997","journal-title":"Psychopharmacology"},{"issue":"6","key":"10.1016\/j.neuroscience.2005.12.037_bib12","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/0031-9384(87)90320-9","article-title":"Taste and bulimia","volume":"41","author":"Drewnowski","year":"1987","journal-title":"Physiol Behav"},{"issue":"2","key":"10.1016\/j.neuroscience.2005.12.037_bib13","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/(SICI)1098-108X(199703)21:2<115::AID-EAT2>3.0.CO;2-O","article-title":"The nutrient intake of women with bulimia nervosa","volume":"21","author":"Gendall","year":"1997","journal-title":"Int J Eat Disord"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib14","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.brainres.2004.10.037","article-title":"Sucrose intake enhances behavioral sensitization produced by cocaine","volume":"1031","author":"Gosnell","year":"2005","journal-title":"Brain Res"},{"issue":"2","key":"10.1016\/j.neuroscience.2005.12.037_bib15","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/eat.10168","article-title":"The role of palatable food and hunger as trigger factors in an animal model of stress-induced binge eating","volume":"34","author":"Hagan","year":"2003","journal-title":"Int J Eat Disord"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib16","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/0091-3057(91)90201-C","article-title":"An animal model of bulimia nervosa","volume":"39","author":"Hagan","year":"1991","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib18","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1097\/00001756-200212030-00010","article-title":"Repeated access to sucrose augments dopamine turnover in the nucleus accumbens","volume":"13","author":"Hajnal","year":"2002","journal-title":"Neuroreport"},{"issue":"1","key":"10.1016\/j.neuroscience.2005.12.037_bib19","doi-asserted-by":"crossref","first-page":"R31","DOI":"10.1152\/ajpregu.00282.2003","article-title":"Oral sucrose stimulation increases accumbens dopamine in the rat","volume":"286","author":"Hajnal","year":"2004","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib20","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/S0006-8993(02)04051-9","article-title":"Cholecystokinin combined with serotonin in the hypothalamus limits accumbens dopamine release while increasing acetylcholine","volume":"963","author":"Helm","year":"2003","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib21","series-title":"Endorphins, eating disorders and other addictive behaviors","author":"Heubner","year":"1993"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib22","first-page":"171","article-title":"Microdialysis studies of brain norepinephrine, serotonin, and dopamine release during ingestive behavior","volume":"Vol. 575","author":"Hoebel","year":"1989"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib23","series-title":"The biology of feast and famine","first-page":"21","article-title":"Neurochemistry of anorexia and bulimia","author":"Hoebel","year":"1992"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib24","series-title":"Well-being","first-page":"558","article-title":"Neural systems for reinforcement and inhibition of behavior","author":"Hoebel","year":"1999"},{"issue":"1","key":"10.1016\/j.neuroscience.2005.12.037_bib25","first-page":"219","article-title":"Preferential stimulation of dopamine release in the nucleus accumbens of freely moving rats by ethanol","volume":"239","author":"Imperato","year":"1986","journal-title":"J Pharmacol Exp Ther"},{"issue":"2","key":"10.1016\/j.neuroscience.2005.12.037_bib26","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1001\/archpsyc.1992.01820020052007","article-title":"Low serotonin and dopamine metabolite concentrations in cerebrospinal fluid from bulimic patients with frequent binge episodes","volume":"49","author":"Jimerson","year":"1992","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib27","series-title":"Eating habits","first-page":"131","article-title":"Palatability","author":"Le Magnen","year":"1987"},{"issue":"1\u20132","key":"10.1016\/j.neuroscience.2005.12.037_bib28","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/0006-8993(91)90946-S","article-title":"A conditioned stimulus decreases extracellular dopamine in the nucleus accumbens after the development of a learned taste aversion","volume":"551","author":"Mark","year":"1991","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib29","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1111\/j.1471-4159.1992.tb10973.x","article-title":"Effects of feeding and drinking on acetylcholine release in the nucleus accumbens, striatum, and hippocampus of freely behaving rats","volume":"58","author":"Mark","year":"1992","journal-title":"J Neurochem"},{"issue":"3","key":"10.1016\/j.neuroscience.2005.12.037_bib30","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/0091-3057(94)90327-1","article-title":"An appetitively conditioned taste elicits a preferential increase in mesolimbic dopamine release","volume":"48","author":"Mark","year":"1994","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib31","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1016\/0024-3205(90)90521-R","article-title":"Atypical endogenous opioid systems in mice in relation to an auto-addiction opioid model of anorexia nervosa","volume":"47","author":"Marrazzi","year":"1990","journal-title":"Life Sci"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib32","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.neuropharm.2004.06.031","article-title":"Molecular mechanisms of drug addiction","volume":"47","author":"Nestler","year":"2004","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib33","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/0006-8993(91)91724-F","article-title":"Dopamine microdialysis in the nucleus accumbens during acute and chronic morphine, naloxone-precipitated withdrawal and clonidine treatment","volume":"566","author":"Pothos","year":"1991","journal-title":"Brain Res"},{"issue":"3","key":"10.1016\/j.neuroscience.2005.12.037_bib34","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.neuroscience.2005.04.043","article-title":"Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell","volume":"134","author":"Rada","year":"2005","journal-title":"Neuroscience"},{"issue":"3","key":"10.1016\/j.neuroscience.2005.12.037_bib35","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0091-3057(99)00219-1","article-title":"Supraadditive effect of d-fenfluramine plus phentermine on extracellular acetylcholine in the nucleus accumbens","volume":"65","author":"Rada","year":"2000","journal-title":"Pharmacol Biochem Behav"},{"issue":"6","key":"10.1016\/j.neuroscience.2005.12.037_bib36","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/0361-9230(85)90106-6","article-title":"On the role of the mouth and gut in the control of saccharin and sugar intake","volume":"14","author":"Sclafani","year":"1985","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib37","first-page":"D.1","article-title":"Sham feeding in rats with chronic, reversible gastric fistulas","volume":"8.6","author":"Smith","year":"1998","journal-title":"Curr Protoc Neurosci"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib38","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.molbrainres.2004.02.013","article-title":"Opiate-like effects of sugar on gene expression in reward areas of the rats brain","volume":"124","author":"Spangler","year":"2004","journal-title":"Brain Res Mol Brain Res"},{"key":"10.1016\/j.neuroscience.2005.12.037_bib39","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/BF02246140","article-title":"Fluctuations in nucleus accumbens dopamine concentration during intravenous cocaine self-administration in rats","volume":"120","author":"Wise","year":"1995","journal-title":"Psychopharmacology"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452205015034?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452205015034?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T15:52:37Z","timestamp":1547826757000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452205015034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S0306452205015034"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2005.12.037","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}