{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T17:01:40Z","timestamp":1759683700621},"reference-count":80,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.neuroscience.2006.01.035","type":"journal-article","created":{"date-parts":[[2006,3,14]],"date-time":"2006-03-14T14:28:24Z","timestamp":1142346504000},"page":"1-11","source":"Crossref","is-referenced-by-count":22,"title":["Effect of neonatal handling on serotonin 1A sub-type receptors in the rat hippocampus"],"prefix":"10.1016","volume":"140","author":[{"given":"A.","family":"Stamatakis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mantelas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Papaioannou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Pondiki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Fameli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Stylianopoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2006.01.035_bib1","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/0031-9384(69)90179-6","article-title":"Effects of early experience on adrenocortical reactivity","volume":"4","author":"Ader","year":"1969","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib2","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1017\/S0033291799008946","article-title":"Pubertal changes in hormone levels and depression in girls","volume":"29","author":"Angold","year":"1999","journal-title":"Psychol Med"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.psyneuen.2005.04.004","article-title":"Depressive disorders","volume":"31","author":"Antonijevic","year":"2006","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib4","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1159\/000123396","article-title":"Serotonin receptor modulation by estrogen in discrete brain nuclei","volume":"35","author":"Biegon","year":"1982","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1523\/JNEUROSCI.02-02-00199.1982","article-title":"Modulation by estradiol of serotonin receptors in brain","volume":"2","author":"Biegon","year":"1982","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib6","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1097\/00004583-199611000-00011","article-title":"Childhood and adolescent depression: a review of the past 10 years. Part I","volume":"35","author":"Birmaher","year":"1996","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib7","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0006-3223(02)01643-8","article-title":"Is there a role for 5-HT1A agonists in the treatment of depression?","volume":"53","author":"Blier","year":"2003","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib8","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/BF00176837","article-title":"Is the forced swimming test a suitable model for revealing antidepressant activity?","volume":"94","author":"Borsini","year":"1988","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib9","doi-asserted-by":"crossref","first-page":"9504","DOI":"10.1073\/pnas.86.23.9504","article-title":"Circumscribed changes of the cerebral cortex in neuropsychiatric disorders of late life","volume":"86","author":"Bowen","year":"1989","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib10","series-title":"Nonradioactive in situ hybridization application manual","first-page":"136","article-title":"Detection of mRNA on paraffin embedded material of the central nervous system with DIG-labeled RNA probes","author":"Breitschopf","year":"1996"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib11","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0278-5846(88)90061-9","article-title":"A regional study of sex differences in rat brain serotonin","volume":"12","author":"Carlsson","year":"1988","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib12","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1523\/JNEUROSCI.13-03-00914.1993","article-title":"Corticosteroids regulate brain hippocampal 5-HT1A receptor mRNA expression","volume":"13","author":"Chalmers","year":"1993","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib13","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0031-9384(03)00149-5","article-title":"Variations in maternal care in the rat as a mediating influence for the effects of environment on development","volume":"79","author":"Champagne","year":"2003","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib14","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1177\/026988110001400203","article-title":"Serotonin, stress and corticoids","volume":"14","author":"Chaouloff","year":"2000","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib15","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1007\/BF02247138","article-title":"Brain 5-HT1 binding sites in depressed suicides","volume":"102","author":"Cheetham","year":"1990","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib16","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0969-8051(00)00108-6","article-title":"Psychopharmacology of 5-HT1A receptors","volume":"27","author":"Cowan","year":"2000","journal-title":"Nucl Med Biol"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib17","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1023\/A:1011123208674","article-title":"Overcrowding induces anxiety and causes loss of serotonin 5HT-1a receptors in rats","volume":"15","author":"Daniels","year":"2000","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib18","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1210\/er.19.3.269","article-title":"Brain corticosteroid receptor balance in health and disease","volume":"19","author":"De Kloet","year":"1998","journal-title":"Endocr Rev"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib19","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0969-8051(00)00119-0","article-title":"Serotonin type-1A receptor imaging in depression","volume":"27","author":"Drevets","year":"2000","journal-title":"Nucl Med Biol"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib20","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/S0006-3223(99)00189-4","article-title":"PET Imaging of serotonin 1A receptor binding in depression","volume":"46","author":"Drevets","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib21","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.neuroscience.2004.04.044","article-title":"Sex differences in behavioral, neurochemical and neuroendocrine effects induced by the forced swim test in rats","volume":"126","author":"Drossopoulou","year":"2004","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib22","first-page":"233","article-title":"Early-life handling stimulation and environmental enrichment","volume":"73","author":"Fernandez-Teruel","year":"2002","journal-title":"Are some of their effects mediated by similar neural mechanisms? Pharmacol Biochem Behav"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib23","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1126\/science.6623080","article-title":"Sex differences in serotonin 1 receptor binding in rat brain","volume":"222","author":"Fischette","year":"1983","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib24","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1159\/000126665","article-title":"Effect of 5,7-dihydroxytryptamine, ovariectomy and gonadal steroids on serotonin receptor binding in rat brain","volume":"59","author":"Frankfurt","year":"1994","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib25","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.1523\/JNEUROSCI.4132-03.2004","article-title":"Neurochemical and behavioral alterations in glucocorticoid receptor-impaired transgenic mice after chronic mild stress","volume":"24","author":"Froger","year":"2004","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib26","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1744-859X-4-8","article-title":"Cellular mechanisms underlying the effects of an early experience on cognitive abilities and affective states","volume":"4","author":"Garoflos","year":"2005","journal-title":"Ann Gen Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib27","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/sj.mp.4001032","article-title":"Organization of the stress system and its dysregulation in melancholic and atypical depression","volume":"7","author":"Gold","year":"2002","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib28","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.pbb.2005.04.013","article-title":"Prenatal stress influences 8-OH-DPAT modulated startle responding and [(3)H]-8-OH-DPAT binding in rats","volume":"81","author":"Griffin","year":"2005","journal-title":"Pharmacol Biochem Behav"},{"issue":"Suppl 1","key":"10.1016\/j.neuroscience.2006.01.035_bib29","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.metabol.2005.01.006","article-title":"Genetics and genomics of depression","volume":"54","author":"Hamet","year":"2005","journal-title":"Metabolism"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib30","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1046\/j.1365-2826.1996.04724.x","article-title":"Modulation of 5-HT1A responsiveness in CA1 pyramidal neurons by in vivo activation of corticosteroid receptors","volume":"8","author":"Hesen","year":"1996","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib31","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0031-9384(69)90023-7","article-title":"Modification of the corticosterone response curve as a function of handling in infancy","volume":"4","author":"Hess","year":"1969","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib32","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S0091-3057(01)00746-8","article-title":"Molecular, pharmacological and functional diversity of 5-HT receptors","volume":"71","author":"Hoyer","year":"2002","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib33","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0960-0760(91)90170-A","article-title":"Effects of corticosteroid hormones on electrical activity in rat hippocampus","volume":"40","author":"Joels","year":"1991","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib34","doi-asserted-by":"crossref","first-page":"13456","DOI":"10.1073\/pnas.96.23.13456","article-title":"Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons","volume":"96","author":"Karten","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib35","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/0006-8993(86)91355-7","article-title":"Female rats are more vulnerable than males in an animal model of depression","volume":"382","author":"Kennett","year":"1986","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib36","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0736-5748(99)00085-4","article-title":"In utero exposure to serotonergic drugs alters neonatal expression of 5-HT(1A) receptor transcripts","volume":"28","author":"Lauder","year":"2000","journal-title":"Int J Dev Neurosci"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib37","first-page":"110","article-title":"Changes in 5-HT1A receptor binding and G-protein activation in the rat brain after estrogen treatment","volume":"30","author":"Le Saux","year":"2005","journal-title":"J Psychiatry Neurosci"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib38","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1126\/science.126.3270.405","article-title":"Infantile experience and resistance to physiological stress","volume":"126","author":"Levine","year":"1957","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib39","first-page":"260","article-title":"Maternal behavior as a mediator of pup adrenocortical function","volume":"746","author":"Levine","year":"1994","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib40","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0006-3223(97)00484-8","article-title":"Regulation of serotonin1A, glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus","volume":"43","author":"Lopez","year":"1998","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib41","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/S0006-3223(98)00224-8","article-title":"Serotonin 1A receptor messenger RNA regulation in the hippocampus after acute stress","volume":"45","author":"Lopez","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib42","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/j.1749-6632.1997.tb52357.x","article-title":"Regulation of 5-HT receptors and the hypothalamic-pituitary-adrenal axis. Implications for the neurobiology of suicide","volume":"836","author":"Lopez","year":"1997","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib43","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.biopsych.2003.09.017","article-title":"Serotonin 5-HT1A, 5-HT1B, and 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia","volume":"55","author":"Lopez-Figueroa","year":"2004","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib44","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.tins.2004.08.001","article-title":"BDNF and 5-HT","volume":"27","author":"Mattson","year":"2004","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib45","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0006-3223(94)00152-S","article-title":"Serotonin receptor binding in a colony model of chronic social stress","volume":"37","author":"McKittrick","year":"1995","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib46","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1159\/000125287","article-title":"Neonatal handling alters adrenocortical negative feedback sensitivity and hippocampal type II glucocorticoid receptor binding in the rat","volume":"50","author":"Meaney","year":"1989","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib47","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0306-4530(91)90072-2","article-title":"The effects of neonatal handling on the development of the adrenocortical response to stress","volume":"16","author":"Meaney","year":"1991","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib48","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1037\/0735-7044.115.5.1111","article-title":"Increased maternal corticosterone levels in rats","volume":"115","author":"Meerlo","year":"2001","journal-title":"Behav Neurosci"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib49","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1046\/j.1365-2826.2000.00445.x","article-title":"Transcriptional repression of the 5-HT1A receptor promoter by corticosterone via mineralocorticoid receptors depends on the cellular context","volume":"12","author":"Meijer","year":"2000","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib50","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1159\/000125951","article-title":"Autoradiographic analyses of the effects of restraint-induced stress on 5-HT1A, 5-HT1C and 5-HT2 receptors in the dorsal hippocampus of male and female rats","volume":"54","author":"Mendelson","year":"1991","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib51","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/0197-0186(91)90063-J","article-title":"Central serotonin1A receptors","volume":"19","author":"Miquel","year":"1991","journal-title":"Neurochem Int"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib52","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0165-3806(90)90204-C","article-title":"The role of serotonin in the development and environmental regulation of type II corticosteroid receptor binding in rat hippocampus","volume":"55","author":"Mitchell","year":"1990","journal-title":"Brain Res Dev Brain Res"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib53","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1037\/h0077599","article-title":"Mother rats interact differently with male and female offspring","volume":"93","author":"Moore","year":"1979","journal-title":"J Comp Physiol Psychol"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib54","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1126\/science.274.5288.740","article-title":"Evidence based health policy","volume":"274","author":"Murray","year":"1996","journal-title":"Science"},{"issue":"Suppl 1","key":"10.1016\/j.neuroscience.2006.01.035_bib55","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.metabol.2005.01.014","article-title":"Depression in women","volume":"54","author":"Noble","year":"2005","journal-title":"Metabolism"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib56","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1037\/0033-2909.115.3.424","article-title":"The emergence of gender differences in depression during adolescence","volume":"115","author":"Nolen-Hoeksema","year":"1994","journal-title":"Psychol Bull"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib57","doi-asserted-by":"crossref","first-page":"14299","DOI":"10.1074\/jbc.M005363200","article-title":"Heterodimerization of mineralocorticoid receptors at a novel negative response element of the 5-HT1A receptor gene","volume":"276","author":"Ou","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib58","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/1025389031000111311","article-title":"Involvement of 5-HT1A receptors in animal tests of anxiety and depression","volume":"6","author":"Overstreet","year":"2003","journal-title":"Stress"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib59","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1159\/000076633","article-title":"Effects of neonatal handling and sex on basal and chronic stress-induced corticosterone and leptin secretion","volume":"79","author":"Panagiotaropoulos","year":"2004","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib60","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1159\/000082516","article-title":"Neonatal handling and gender modulate brain monoamines and plasma corticosterone levels following repeated stressors in adulthood","volume":"80","author":"Panagiotaropoulos","year":"2004","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib61","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0306-4522(02)00129-X","article-title":"Effects of neonatal handling on basal and stress-induced monoamine levels in the male and female rat brain","volume":"114","author":"Papaioannou","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib62","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0166-4328(01)00334-5","article-title":"Sex differences in the effects of neonatal handling on the animal\u2019s response to stress and the vulnerability to depressive behaviour","volume":"129","author":"Papaioannou","year":"2002","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib63","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1046\/j.1365-2826.2003.01010.x","article-title":"Gender specific effect of neonatal handling on stress reactivity of adolescent rats","volume":"15","author":"Park","year":"2003","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib64","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0006-8993(02)03243-2","article-title":"Effects of sex, age, and aggressive traits in man on brain serotonin 5-HT1A receptor binding potential measured by PET using [C-11]WAY-100635","volume":"954","author":"Parsey","year":"2002","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib65","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"1986"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib66","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/266730a0","article-title":"Depression","volume":"266","author":"Porsolt","year":"1977","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib67","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.neuroscience.2003.10.008","article-title":"Region specific changes in forebrain 5-hydroxytryptamine1A and 5-hydroxytryptamine2A receptors in isolation-reared rats","volume":"123","author":"Preece","year":"2004","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib68","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0169-328X(97)00317-3","article-title":"Environmental enrichment selectively increases 5-HT1A receptor mRNA expression and binding in the rat hippocampus","volume":"53","author":"Rasmuson","year":"1998","journal-title":"Mol Brain Res"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib69","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0165-3806(94)90167-8","article-title":"Neurotrophic effects of ipsapirone and other 5-HT1A receptor agonists on septal cholinergic neurons in culture","volume":"82","author":"Riad","year":"1994","journal-title":"Dev Brain Res"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib70","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0165-3806(90)90092-D","article-title":"5-HT1A receptors control neurite branching during development","volume":"56","author":"Sikich","year":"1990","journal-title":"Dev Brain Res"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib71","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0361-9230(95)02146-9","article-title":"Median eminence corticotrophin releasing hormone content following prenatal stress and neonatal handling","volume":"40","author":"Smythe","year":"1996","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib72","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/0031-9384(94)90089-2","article-title":"The interaction between prenatal stress and neonatal handling on nociceptive response latencies in male and female rats","volume":"55","author":"Smythe","year":"1994","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib73","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0165-3806(94)90103-1","article-title":"Neonatal handling alters serotonin (5-HT) turnover and 5-HT2 receptor binding in selected brain regions","volume":"80","author":"Smythe","year":"1994","journal-title":"Dev Brain Res"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib74","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1523\/JNEUROSCI.17-07-02626.1997","article-title":"Prenatal stress induces high anxiety and postnatal handling induces low anxiety in adult offspring","volume":"17","author":"Vall\u00e9e","year":"1997","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib75","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/S0006-8993(99)02307-0","article-title":"Maternal deprivation regulates serotonin 1A and 2A receptors in the infant rat","volume":"855","author":"Vazquez","year":"2000","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib76","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1196\/annals.1296.030","article-title":"Basal and stress-induced differences in HPA axis, 5-HT responsiveness, and hippocampal cell proliferation in two mouse lines","volume":"1018","author":"Veenema","year":"2004","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib77","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0303-7207(01)00635-9","article-title":"Early environmental regulation of hippocampal glucocorticoid receptor gene expression","volume":"185","author":"Weaver","year":"2001","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib78","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1074\/jbc.275.2.1321","article-title":"Regulation of the rat serotonin-1A receptor gene by corticosteroids","volume":"275","author":"Wissink","year":"2000","journal-title":"Biol Chem"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib79","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1196\/annals.1308.013","article-title":"Puberty, ovarian steroids, and stress","volume":"1021","author":"Young","year":"2004","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.neuroscience.2006.01.035_bib80","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0306-4522(99)00234-1","article-title":"Sex differences in expression of serotonin receptors (subtypes 1A and 2A) in rat brain","volume":"94","author":"Zhang","year":"1999","journal-title":"Neuroscience"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030645220600145X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030645220600145X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T09:23:21Z","timestamp":1555493001000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S030645220600145X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":80,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S030645220600145X"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2006.01.035","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}