{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:42:12Z","timestamp":1790617332044,"version":"4.1.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.neuroscience.2006.04.072","type":"journal-article","created":{"date-parts":[[2006,6,13]],"date-time":"2006-06-13T10:50:55Z","timestamp":1150195855000},"page":"1281-1287","source":"Crossref","is-referenced-by-count":59,"title":["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced acute transient dystonia in monkeys associated with low striatal dopamine"],"prefix":"10.1016","volume":"141","author":[{"given":"S.D.","family":"Tabbal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.W.","family":"Mink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.V.","family":"Antenor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.L.","family":"Carl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.M.","family":"Moerlein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.S.","family":"Perlmutter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2006.04.072_bib1","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1212\/WNL.59.3.445","article-title":"Dopamine transmission in DYT1 dystonia","volume":"59","author":"Augood","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib2","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1212\/WNL.35.7.949","article-title":"Permanent human parkinsonism due to 1-methyl-4-phenyl-1,2,3,6, tetrahydropyridine (MPTP)","volume":"35","author":"Ballard","year":"1985","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib3","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0024-3205(86)90431-5","article-title":"Hemiparkinsonism in monkeys after unilateral internal carotid artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)","volume":"39","author":"Bankiewicz","year":"1986","journal-title":"Life Sci"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib4","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1152\/jn.1994.72.2.507","article-title":"The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of Parkinsonism","volume":"72","author":"Bergman","year":"1994","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib5","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0306-4522(97)00226-1","article-title":"Compensatory effects of glutamatergic inputs to the substantia nigra pars compacta in experimental parkinsonism","volume":"81","author":"Bezard","year":"1997","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib6","doi-asserted-by":"crossref","first-page":"2167","DOI":"10.1046\/j.1460-9568.1999.00627.x","article-title":"Involvement of the subthalamic nucleus in glutamatergic compensatory mechanisms","volume":"11","author":"Bezard","year":"1999","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib7","doi-asserted-by":"crossref","first-page":"4546","DOI":"10.1073\/pnas.80.14.4546","article-title":"A primate model of parkinsonism","volume":"80","author":"Burns","year":"1983","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib8","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1056\/NEJM197011052831901","article-title":"Necrotizing angiitis associated with drug abuse","volume":"283","author":"Citron","year":"1970","journal-title":"N Engl J Med"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib9","series-title":"Advances in neurology","first-page":"1","article-title":"Concept and classification of dystonia","author":"Fahn","year":"1988"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib10","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/BF00735822","article-title":"Dystonic reactions following neuroleptics","volume":"47","author":"Garver","year":"1976","journal-title":"Psychopharmacologia"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib11","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0014-2999(95)00086-Z","article-title":"Short- and long-term changes in striatal and extrastriatal dopamine uptake sites in the MPTP-treated common marmoset","volume":"277","author":"Gnanalingham","year":"1995","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib12","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/0024-3205(86)90336-X","article-title":"\u201cIn vivo\u201d visualization by positron emission tomography of the progressive striatal dopamine receptor damage occurring in MPTP-intoxicated non-human primates","volume":"39","author":"Hantraye","year":"1986","journal-title":"Life Sci"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib13","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1136\/jnnp.57.4.460","article-title":"Lessons from a remarkable family with dopa-responsive dystonia","volume":"57","author":"Harwood","year":"1994","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib14","first-page":"309","article-title":"Die Topische Lokalisation und das Verhalten von Noradrenalin und Dopamin in der Substantia Nigra des normalen und Parkinsonkranken Menschen","volume":"75","author":"Hornykiewicz","year":"1963","journal-title":"Wien Klin Wochenschr"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib15","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/0006-8993(90)90780-F","article-title":"The evolution of nigrostriatal neurochemical changes in the MPTP-treated squirrel monkey","volume":"531","author":"Irwin","year":"1990","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib16","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.jchromb.2006.03.027","article-title":"Modified high-performance liquid chromatography with electrochemical detection method for plasma measurement of levodopa, 3-O-methyldopa, dopamine, carbidopa and 3,4-dihydroxyphenyl acetic acid","volume":"836","author":"Karimi","year":"2006","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib17","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1093\/hmg\/4.7.1209","article-title":"Recessively inherited L-DOPA-responsive dystonia caused by a point mutation (Q381K) in the tyrosine hydroxylase gene","volume":"4","author":"Knappskog","year":"1995","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib18","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1212\/WNL.31.4.434","article-title":"Neuroleptic-induced acute dystonic reactions may be due to enhanced dopamine release on to supersensitive postsynaptic receptors","volume":"31","author":"Kolbe","year":"1981","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib19","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0014-2999(89)90826-1","article-title":"Systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine reduces the release of [3H]dopamine from rat striatal slices","volume":"169","author":"Kurstjens","year":"1989","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib20","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1471-4159.1987.tb13129.x","article-title":"Kinetic modeling of receptor-ligand binding applied to positron emission tomographic studies with neuroleptic tracers","volume":"48","author":"Logan","year":"1987","journal-title":"J Neurochem"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib21","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1056\/NEJM200005253422103","article-title":"Association between early-onset Parkinson\u2019s disease and mutations in the parkin gene","volume":"342","author":"L\u00fccking","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib22","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1006\/exnr.1994.1007","article-title":"On the role of enkephalin cotransmission in the GABAergic striatal efferents to the globus pallidus","volume":"125","author":"Maneuf","year":"1994","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib23","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0301-0082(96)00042-1","article-title":"The basal ganglia","volume":"50","author":"Mink","year":"1996","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib24","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1001\/archneur.60.10.1365","article-title":"The basal ganglia and involuntary movements","volume":"60","author":"Mink","year":"2003","journal-title":"Arch Neurol"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib25","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/0883-2889(92)90217-3","article-title":"Regioselective radiofluorodestannylation with [18F]F2 and [18F]CH3COOF","volume":"43","author":"Namavari","year":"1992","journal-title":"Int J Rad Appl Instrum [A]"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib26","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1002\/mds.870130219","article-title":"Imaging the pre- and postsynaptic side of striatal dopaminergic synapses in idiopathic cervical dystonia","volume":"13","author":"Naumann","year":"1998","journal-title":"Mov Disord"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib27","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1002\/ana.410320502","article-title":"Long-term treatment response and fluorodopa positron emission tomographic scanning of parkinsonism in a family with dopa-responsive dystonia","volume":"32","author":"Nygaard","year":"1992","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib28","first-page":"619","article-title":"Strong allelic association between the torsion dystonia gene (DYT1) and loci on chromosome 9q34 in Ashkenazi Jews","volume":"50","author":"Ozelius","year":"1992","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib29","first-page":"140","article-title":"PET measurements of dopaminergic pathways in the brain","volume":"43","author":"Perlmutter","year":"1999","journal-title":"Q J Nucl Med"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib30","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1523\/JNEUROSCI.11-05-01381.1991","article-title":"Non-steady-state measurement of in vivo radioligand binding with positron emission tomography","volume":"11","author":"Perlmutter","year":"1991","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib31","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1523\/JNEUROSCI.17-02-00843.1997","article-title":"Decreased [18F]spiperone binding in putamen in idiopathic focal dystonia","volume":"17","author":"Perlmutter","year":"1997","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib32","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1212\/WNL.49.5.1432","article-title":"MPTP induces dystonia and parkinsonism","volume":"49","author":"Perlmutter","year":"1997","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib33","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0014-2999(93)90800-W","article-title":"Age-related effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment of common marmosets","volume":"230","author":"Rose","year":"1993","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib34","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/BF00178501","article-title":"Acute dystonia induced by neuroleptic drugs","volume":"88","author":"Rupniak","year":"1986","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib35","doi-asserted-by":"crossref","first-page":"6643","DOI":"10.1523\/JNEUROSCI.19-15-06643.1999","article-title":"Striatal preproenkephalin gene expression is upregulated in acute but not chronic parkinsonian monkeys","volume":"19","author":"Schneider","year":"1999","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib36","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/0006-8993(94)01332-C","article-title":"Differential recovery of volitional motor function, lateralized cognitive function, dopamine agonist-induced rotation and dopaminergic parameters in monkeys made hemi-parkinsonian by intracarotid MPTP infusion","volume":"672","author":"Schneider","year":"1995","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib37","doi-asserted-by":"crossref","first-page":"6417","DOI":"10.1523\/JNEUROSCI.0836-04.2004","article-title":"Role of external pallidal segment in primate parkinsonism","volume":"24","author":"Soares","year":"2004","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib38","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0143-4179(88)90039-X","article-title":"Levels of Met-enkephalin, Leu-enkephalin, substance P and cholecystokinin in the brain of the common marmoset following long term 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine treatment","volume":"12","author":"Taquet","year":"1988","journal-title":"Neuropeptides"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib39","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF02260885","article-title":"Neuropeptide levels in the basal ganglia of aged common marmosets following prolonged treatment with MPTP","volume":"3","author":"Taylor","year":"1991","journal-title":"J Neural Transm Park Dis Dement Sect"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib40","doi-asserted-by":"crossref","first-page":"7776","DOI":"10.1523\/JNEUROSCI.16-23-07776.1996","article-title":"Dynamic changes in striatal dopamine D2 and D3 receptor protein and mRNA in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) denervation in baboons","volume":"16","author":"Todd","year":"1996","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib41","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/BF00971569","article-title":"Parkinson-like disease by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) toxicity in Macaca fascicularis","volume":"19","author":"Villa","year":"1994","journal-title":"Neurochem Res"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib42","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1097\/00004728-199307000-00004","article-title":"MRI-PET registration with automated algorithm","volume":"14","author":"Woods","year":"1993","journal-title":"J Comput Assist Tomogr"},{"key":"10.1016\/j.neuroscience.2006.04.072_bib43","doi-asserted-by":"crossref","first-page":"S38","DOI":"10.1002\/mds.870040506","article-title":"The dopamine motor system","volume":"4","author":"Wooten","year":"1989","journal-title":"Mov Disord"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452206006208?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452206006208?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,19]],"date-time":"2019-04-19T05:53:34Z","timestamp":1555653214000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452206006208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S0306452206006208"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2006.04.072","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}