{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T11:40:05Z","timestamp":1791114005009,"version":"4.1.0"},"reference-count":70,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1016\/j.neuroscience.2006.12.007","type":"journal-article","created":{"date-parts":[[2007,1,11]],"date-time":"2007-01-11T07:58:45Z","timestamp":1168502325000},"page":"738-750","source":"Crossref","is-referenced-by-count":127,"title":["Both long and brief maternal separation produces persistent changes in tissue levels of brain monoamines in middle-aged female rats"],"prefix":"10.1016","volume":"145","author":[{"given":"L.","family":"Arborelius","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.B.","family":"Eklund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2006.12.007_bib1","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1111\/j.1749-6632.1999.tb09317.x","article-title":"Enduring neurochemical effects of early maternal separation on limbic structures","volume":"877","author":"Andersen","year":"1999","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib2","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/s00213-004-1883-x","article-title":"Increased responsiveness of 5-HT cell firing to citalopram in adult rats previously subjected to maternal deprivation","volume":"176","author":"Arborelius","year":"2004","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1677\/joe.0.1600001","article-title":"The role of corticotropin-releasing factor in depression and anxiety disorders","volume":"160","author":"Arborelius","year":"1999","journal-title":"J Endocrinol"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib4","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0091-6773(75)90636-7","article-title":"Rodent sex differences in emotional and related behavior","volume":"14","author":"Archer","year":"1975","journal-title":"Behav Biol"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib5","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib6","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1111\/j.1460-9568.2004.03286.x","article-title":"Influence of early postnatal rearing conditions on mesocorticolimbic dopamine and behavioural responses to psychostimulants and stressors in adult rats","volume":"19","author":"Brake","year":"2004","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib7","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0893-133X(99)00110-4","article-title":"The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat","volume":"22","author":"Caldji","year":"2000","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib8","doi-asserted-by":"crossref","first-page":"9102","DOI":"10.1523\/JNEUROSCI.2345-05.2005","article-title":"Early experience modifies the postnatal assembly of autonomic emotional motor circuits in rats","volume":"25","author":"Card","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib9","doi-asserted-by":"crossref","first-page":"28S","DOI":"10.1016\/S0893-133X(99)00008-1","article-title":"Serotonin and stress","volume":"21","author":"Chaouloff","year":"1999","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib9a","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0006-8993(92)91079-T","article-title":"Selective activation of mesoamygdaloid dopamine neurons by conditioned stress: attenuation by diazepam","volume":"590","author":"Coco","year":"1992","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib10","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0197-4580(03)00042-3","article-title":"Reduced cortical noradrenergic neurotransmission is associated with increased neophobia and impaired spatial memory in aged rats","volume":"25","author":"Collier","year":"2004","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib11","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1023\/B:MEBR.0000027412.19664.b3","article-title":"Maternal separation in rats leads to anxiety-like behavior and a blunted ACTH response and altered neurotransmitter levels in response to a subsequent stressor","volume":"19","author":"Daniels","year":"2004","journal-title":"Metabol Brain Dis"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib13","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1176\/appi.ajp.157.7.1175","article-title":"N-Acetylaspartate concentration in the anterior cingulated of maltreated children and adolescents with PTSD","volume":"157","author":"De Bellis","year":"2000","journal-title":"Am J Psychiatry"},{"issue":"Suppl 1","key":"10.1016\/j.neuroscience.2006.12.007_bib14","first-page":"65","article-title":"Plasticity and function of brain corticosteroid receptors during aging","volume":"125","author":"De Kloet","year":"1991","journal-title":"Acta Endocrinol"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib15","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0006-8993(86)91581-7","article-title":"Brain serotonin and catecholamine responses to repeated stress in rats","volume":"367","author":"De Souza","year":"1986","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib16","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0378-3782(79)90022-7","article-title":"Comparative aspects of the brain growth spurt","volume":"1","author":"Dobbing","year":"1979","journal-title":"Early Hum Dev"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib17","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/S0959-4388(00)00203-8","article-title":"Neuroimaging and neuropathological studies of depression: implications for the cognitive-emotional features of mood disorders","volume":"11","author":"Drevets","year":"2001","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib18","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.bbr.2006.05.015","article-title":"Twice daily long maternal separations in Wistar rats decreases anxiety-like behaviour in females but does not affect males","volume":"172","author":"Eklund","year":"2006","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib19","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/0306-4530(96)00006-6","article-title":"Endocrine and behavioral effects of airpuff-startle in rats","volume":"21","author":"Engelmann","year":"1996","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib20","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1016\/S0006-3223(99)00237-1","article-title":"The role of corticotropin-releasing factor-norepinephrine systems in mediating the effects of early experience on the development of behavioral and endocrine responses to stress","volume":"46","author":"Francis","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib21","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.neuroscience.2005.07.042","article-title":"Early life experience alters behaviour during social defeat: focus on serotonergic systems","volume":"136","author":"Gardner","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib22","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1046\/j.1460-9568.2003.02668.x","article-title":"Early life adversity programs changes in central 5-HT neuronal functioning in adulthood","volume":"17","author":"Gartside","year":"2003","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib23","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/(SICI)1098-2396(199904)32:1<37::AID-SYN5>3.0.CO;2-4","article-title":"Maternal deprivation of neonatal rats produces enduring changes in dopamine function","volume":"32","author":"Hall","year":"1999","journal-title":"Synapse"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib24","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0006-3223(01)01157-X","article-title":"The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies","volume":"49","author":"Heim","year":"2001","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib25","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/0091-3057(94)90243-7","article-title":"Regional changes in dopamine and serotonin activation with various intensity of physical and psychological stress in the rat brain","volume":"49","author":"Inoue","year":"1994","journal-title":"Pharm Biochem Behav"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib26","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/s00213-005-2232-4","article-title":"Effects of early maternal separation on ethanol intake, GABA receptors and metabolizing enzymes in adult rats","volume":"181","author":"Jaworski","year":"2005","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib27","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0031-9384(91)90039-Q","article-title":"Sex differences in animal tests of anxiety","volume":"49","author":"Johnston","year":"1991","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib28","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0091-3057(02)00781-5","article-title":"Long-lasting changes in stress-induced corticosterone response and anxiety-like behaviors as a consequence of neonatal maternal separation in Long-Evans rats","volume":"73","author":"Kalinichev","year":"2002","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib29","series-title":"Modern techniques in neuroscience research","first-page":"1149","article-title":"Monitoring chemistry of brain microenvironment: biosensors, microdialysis and related techniques","author":"Kehr","year":"1999"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib30","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1001\/archpsyc.1992.01820020029004","article-title":"Childhood parental loss and adult psychopathology in women","volume":"49","author":"Kendler","year":"1992","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib31","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/S0006-8993(97)00287-4","article-title":"The effects of different stressor on extracellular 5-hydroxytryptamine and 5-hydroxyindoleacetic acid","volume":"760","author":"Kirby","year":"1997","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib32","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/S0149-7634(99)00026-3","article-title":"Coping styles in animals: current status in behavior and stress-physiology","volume":"23","author":"Koolhaas","year":"1999","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib33","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1159\/000126099","article-title":"Diurnal corticotropin-releasing hormone mRNA variation in the hypothalamus exhibits a rhythm distinct from that of plasma corticosterone","volume":"55","author":"Kwak","year":"1992","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib34","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0079-6123(08)62132-9","article-title":"Long-term behavioral and neuroendocrine adaptations to adverse early experience","volume":"122","author":"Ladd","year":"2000","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib35","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1210\/en.137.4.1212","article-title":"Persistent changes in corticotropin-releasing factor neuronal systems induced by maternal deprivation","volume":"137","author":"Ladd","year":"1996","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib36","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/0006-8993(79)90311-1","article-title":"Blockade by benzodiazepines of the selective high increase in dopamine turnover induced by stress in mesocortical dopaminergic neurons of the rat","volume":"168","author":"Lavielle","year":"1978","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib37","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1515\/REVNEURO.2000.11.4.383","article-title":"Long-term biobehavioral effects of maternal separation in the rat: consistent or confusing?","volume":"11","author":"Lehmann","year":"2000","journal-title":"Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib38","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0006-8993(79)90287-7","article-title":"Development of the noradrenergic innervation of neocortex","volume":"162","author":"Levitt","year":"1979","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib39","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0361-9230(82)90077-6","article-title":"An immunohistochemical study of serotonin neuron development in the rat: ascending pathways and terminal fields","volume":"8","author":"Lidov","year":"1982","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib40","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1046\/j.1365-2826.2000.00422.x","article-title":"Influence of neonatal rearing conditions on stress-induced adrenocorticotropin responses and norepinephrine release in the hypothalamic paraventricular nucleus","volume":"12","author":"Liu","year":"2000","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib41","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.neubiorev.2005.03.021","article-title":"Stressor controllability and learned helplessness: the roles of dorsal raphe nucleus, serotonin and corticotropin-releasing factor","volume":"29","author":"Maier","year":"2005","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib42","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1002\/dev.20027","article-title":"Maternal separation alters maternal care, but has minor effects on behavior and brain opioid peptides in adult offspring","volume":"45","author":"Marmendal","year":"2004","journal-title":"Dev Psychobiol"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib43","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0006-3223(03)00004-0","article-title":"A magnetic resonance spectroscopic imaging study of adult nonhuman primates exposed to early-life stressors","volume":"54","author":"Mathew","year":"2003","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/1098-2396(200104)40:1<1::AID-SYN1020>3.0.CO;2-E","article-title":"Periodic maternal separation of neonatal rats produces region- and sex-specific effects on biogenic amine content in postmortem adult brain","volume":"40","author":"Matthews","year":"2001","journal-title":"Synapse"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib45","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.neuron.2005.02.014","article-title":"Deep brain stimulation for treatment-resistant depression","volume":"45","author":"Mayberg","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib46","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1146\/annurev.neuro.24.1.1161","article-title":"Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations","volume":"24","author":"Meaney","year":"2001","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib47","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0306-4530(01)00040-3","article-title":"Environmental regulation of mesolimbic dopamine systems: a neurobiological mechanism for vulnerability to drug abuse?","volume":"27","author":"Meaney","year":"2002","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib48","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0893-133X(97)00194-2","article-title":"Serotonin in aging, late-life depression, and Alzheimer\u2019s disease: the emerging role of functional imaging","volume":"18","author":"Meltzer","year":"1998","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib49","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0306-4522(99)00014-7","article-title":"The role of mesoprefrontal dopamine neurons in the acquisition and expression of conditioned fear in the rat","volume":"92","author":"Morrow","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib50","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/S0006-3223(01)01371-3","article-title":"5-HT1B mRNA regulation in two animal models of altered stress reactivity","volume":"51","author":"Neumaier","year":"2002","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib51","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1007\/s00213-004-1950-3","article-title":"Implications of genetic research on the role of the serotonin in depression: emphasis on the serotonin type 1A receptor and the serotonin transporter","volume":"174","author":"Neumeister","year":"2004","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib52","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1016\/S0031-9384(96)00225-9","article-title":"Effects of postnatal handling of rats on emotional, HPA-axis, and prolactin reactivity to novelty and conflict","volume":"60","author":"N\u00fa\u00f1ez","year":"1996","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib53","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"1998"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib54","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.nut.2006.05.005","article-title":"Alterations in glutamine synthetase activity in rat skeletal muscle are associated with advanced age","volume":"22","author":"Pinel","year":"2006","journal-title":"Nutrition"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib55","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0306-4522(03)00499-8","article-title":"Long-term effects of maternal separation on ethanol intake and brain opioid and dopamine receptors in male Wistar rats","volume":"121","author":"Ploj","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib56","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0169-328X(93)90189-V","article-title":"Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content, and stress-induced release in adult rats","volume":"18","author":"Plotsky","year":"1993","journal-title":"Mol Brain Res"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib57","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.1038\/sj.npp.1300769","article-title":"Long-term consequences of neonatal rearing on central corticotropin-releasing factor systems in adult male rat offspring","volume":"30","author":"Plotsky","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib58","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0149-7634(03)00009-5","article-title":"Long-term neurobehavioural impact of the postnatal environment in rats: manipulations, effects and mediating mechanisms","volume":"27","author":"Pryce","year":"2003","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib59","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/1520-6394(2000)12:1+<2::AID-DA2>3.0.CO;2-4","article-title":"Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders","volume":"12","author":"Ressler","year":"2000","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib60","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/0028-3908(87)90228-0","article-title":"The effects of footshock stress on regional brain dopamine metabolism and pituitary b-endorphin release in rats previously sensitized to amphetamine","volume":"26","author":"Robinson","year":"1987","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib61","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1192\/bjp.174.2.112","article-title":"Early life family disadvantages and major depression in adulthood","volume":"174","author":"Sadowski","year":"1999","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib62","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1017\/S0954579401003029","article-title":"Early adverse experience as a developmental risk factor for later psychopathology: evidence from rodent and primate models","volume":"13","author":"Sanchez","year":"2001","journal-title":"Dev Psychopathol"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib63","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.physbeh.2004.02.019","article-title":"Effects of neonatal handling on the behavior and prolactin stress response in male and female rats at various ages and estrous cycle phases of females","volume":"81","author":"Severino","year":"2004","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib64","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0165-3806(94)90103-1","article-title":"Neonatal handling alters serotonin (5-HT) turnover and 5-HT2 receptor binding in selected brain regions: relationship to the handling effect on glucocorticoid receptor expression","volume":"80","author":"Smythe","year":"1994","journal-title":"Dev Brain Res"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib65","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1080\/102538900410001679310","article-title":"Hemispheric asymmetry in stress processing in rat prefrontal cortex and the role of mesocortical dopamine","volume":"7","author":"Sullivan","year":"2004","journal-title":"Stress"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib66","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1111\/j.1365-2826.2003.01108.x","article-title":"Monoaminergic activity in subregions of the raph\u00e9 nuclei elicited by prior stress and the neuropeptide corticotropin-releasing factor","volume":"15","author":"Summers","year":"2003","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib67","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.neuroscience.2006.02.008","article-title":"Maternal separation alters serotonergic transporter densities and serotonergic 1A receptors in rat brain","volume":"140","author":"Vicentic","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib68","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1001\/archpsyc.1977.01770130100011","article-title":"Sex differences and the epidemiology of depression","volume":"34","author":"Weissman","year":"1977","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib69","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0031-9384(98)00300-X","article-title":"Periodic maternal deprivation induces gender-dependent alternations in behavioural and neuroendocrine response to emotional stress in adult rats","volume":"66","author":"Wigger","year":"1999","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2006.12.007_bib70","series-title":"Psychopharmacology: The fourth generation of progress","first-page":"921","article-title":"Dopaminergic mechanisms in depression and mania","author":"Willner","year":"1995"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452206016800?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452206016800?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,9]],"date-time":"2019-01-09T21:27:31Z","timestamp":1547069251000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452206016800"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":70,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["S0306452206016800"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2006.12.007","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}