{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T09:13:48Z","timestamp":1791105228432,"version":"4.1.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1016\/j.neuroscience.2007.10.048","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T21:29:06Z","timestamp":1196112546000},"page":"476-488","source":"Crossref","is-referenced-by-count":170,"title":["Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities"],"prefix":"10.1016","volume":"151","author":[{"given":"M.M.","family":"Fraser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.T.","family":"Bayazitov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.S.","family":"Zakharenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.J.","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2007.10.048_bib1","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1093\/jnci\/91.22.1922","article-title":"Mutational spectra of PTEN\/MMAC1 gene: a tumor suppressor with lipid phosphatase activity","volume":"91","author":"Ali","year":"1999","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib2","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/ng782","article-title":"Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease","volume":"29","author":"Backman","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib3","doi-asserted-by":"crossref","first-page":"5100","DOI":"10.1128\/MCB.22.14.5100-5113.2002","article-title":"Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation","volume":"22","author":"Bajenaru","year":"2002","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib4","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1136\/jmg.2004.024646","article-title":"Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations","volume":"42","author":"Butler","year":"2005","journal-title":"J Med Genet"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib5","doi-asserted-by":"crossref","first-page":"14368","DOI":"10.1073\/pnas.2336098100","article-title":"Time-restricted role for dendritic activation of the mTOR-p70S6K pathway in the induction of late-phase long-term potentiation in the CA1","volume":"100","author":"Cammalleri","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib6","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1242\/jcs.02801","article-title":"PTEN couples Sema3A signalling to growth cone collapse","volume":"119","author":"Chadborn","year":"2006","journal-title":"J Cell Sci"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib7","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.canlet.2005.11.042","article-title":"PTEN function in normal and neoplastic growth","volume":"241","author":"Chow","year":"2006","journal-title":"Cancer Lett"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib8","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/1235","article-title":"Pten is essential for embryonic development and tumour suppression","volume":"19","author":"Di Cristofano","year":"1998","journal-title":"Nat Genet"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib9","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/humu.10257","article-title":"PTEN: one gene, many syndromes","volume":"22","author":"Eng","year":"2003","journal-title":"Hum Mutat"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib10","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/897","article-title":"PTEN and inherited hamartoma-cancer syndromes","volume":"19","author":"Eng","year":"1998","journal-title":"Nat Genet"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib11","first-page":"329","article-title":"Studies with the Golgi method in central gangliogliomas and dysplastic gangliocytoma of the cerebellum (Lhermitte-Duclos disease)","volume":"5","author":"Ferrer","year":"1990","journal-title":"Histol Histopathol"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib12","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0165-0173(02)00158-3","article-title":"Dendritic spine pathology: cause or consequence of neurological disorders?","volume":"39","author":"Fiala","year":"2002","journal-title":"Brain Res Brain Res Rev"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib13","doi-asserted-by":"crossref","first-page":"3151","DOI":"10.1038\/sj.onc.1207542","article-title":"Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression","volume":"23","author":"Fingar","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib14","doi-asserted-by":"crossref","first-page":"7773","DOI":"10.1158\/0008-5472.CAN-04-2487","article-title":"Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo","volume":"64","author":"Fraser","year":"2004","journal-title":"Cancer Res"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib15","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/BF01644067","article-title":"Lhermitte-Duclos disease (diffuse hypertrophy of the cerebellum)","volume":"3","author":"Gessaga","year":"1980","journal-title":"Neurosurg Rev"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib16","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1002\/ajmg.1477","article-title":"PTEN mutation in a family with Cowden syndrome and autism","volume":"105","author":"Goffin","year":"2001","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib17","doi-asserted-by":"crossref","first-page":"18802","DOI":"10.1074\/jbc.M512524200","article-title":"Roles of glutamate receptors and the mammalian target of rapamycin (mTOR) signaling pathway in activity-dependent dendritic protein synthesis in hippocampal neurons","volume":"281","author":"Gong","year":"2006","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib18","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1471-4159.2004.02949.x","article-title":"Activation of Akt\/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer\u2019s disease pathology","volume":"93","author":"Griffin","year":"2005","journal-title":"J Neurochem"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib19","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1126\/science.1065518","article-title":"Negative regulation of neural stem\/progenitor cell proliferation by the Pten tumor suppressor gene in vivo","volume":"294","author":"Groszer","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib20","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1007\/BF00304477","article-title":"Immunohistochemistry and proliferative activity in Lhermitte-Duclos disease","volume":"84","author":"Hair","year":"1992","journal-title":"Acta Neuropathol (Berl)"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib21","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/S0002-9440(10)64615-9","article-title":"Astrocytes give rise to oligodendrogliomas and astrocytomas after gene transfer of polyoma virus middle T antigen in vivo","volume":"157","author":"Holland","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib22","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1172\/JCI20513","article-title":"Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas","volume":"113","author":"Horie","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib23","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1038\/nn1797","article-title":"Bace1 modulates myelination in the central and peripheral nervous system","volume":"9","author":"Hu","year":"2006","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib24","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.neuron.2006.02.006","article-title":"Astrocytes promote myelination in response to electrical impulses","volume":"49","author":"Ishibashi","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib25","doi-asserted-by":"crossref","first-page":"11300","DOI":"10.1523\/JNEUROSCI.2270-05.2005","article-title":"Control of dendritic arborization by the phosphoinositide-3\u2032-kinase-Akt-mammalian target of rapamycin pathway","volume":"25","author":"Jaworski","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib26","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0092-8674(04)01258-9","article-title":"Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators","volume":"120","author":"Jiang","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib27","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1242\/dev.00392","article-title":"Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production","volume":"130","author":"Kimura","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib28","doi-asserted-by":"crossref","first-page":"11288","DOI":"10.1523\/JNEUROSCI.2284-05.2005","article-title":"Regulation of dendritic morphogenesis by Ras-PI3K-Akt-mTOR and Ras-MAPK signaling pathways","volume":"25","author":"Kumar","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib29","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.neuron.2006.03.023","article-title":"Pten regulates neuronal arborization and social interaction in mice","volume":"50","author":"Kwon","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib30","doi-asserted-by":"crossref","first-page":"12923","DOI":"10.1073\/pnas.2132711100","article-title":"mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo","volume":"100","author":"Kwon","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib31","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1038\/ng781","article-title":"Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease","volume":"29","author":"Kwon","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib32","doi-asserted-by":"crossref","first-page":"3653","DOI":"10.1242\/jcs.02490","article-title":"PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone","volume":"118","author":"Laurino","year":"2005","journal-title":"J Cell Sci"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib33","doi-asserted-by":"crossref","first-page":"4159","DOI":"10.1242\/dev.129.17.4159","article-title":"Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland","volume":"129","author":"Li","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib34","doi-asserted-by":"crossref","first-page":"599","DOI":"10.3171\/jns.1988.69.4.0599","article-title":"Recurrent Lhermitte-Duclos disease in a child","volume":"69","author":"Marano","year":"1988","journal-title":"J Neurosurg"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib35","doi-asserted-by":"crossref","first-page":"3513","DOI":"10.1242\/dev.129.14.3513","article-title":"PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum","volume":"129","author":"Marino","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib36","doi-asserted-by":"crossref","first-page":"10199","DOI":"10.1523\/JNEUROSCI.1223-06.2006","article-title":"Age-independent synaptogenesis by phosphoinositide 3 kinase","volume":"26","author":"Martin-Pena","year":"2006","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib37","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1046\/j.1471-4159.2004.02302.x","article-title":"PIP3 is involved in neuronal polarization and axon formation","volume":"89","author":"Menager","year":"2004","journal-title":"J Neurochem"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib38","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1126\/science.1095862","article-title":"Axonal neuregulin-1 regulates myelin sheath thickness","volume":"304","author":"Michailov","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib39","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1002\/glia.20142","article-title":"In vivo analysis of oligodendrocyte lineage development in postnatal FGF2 null mice","volume":"49","author":"Murtie","year":"2005","journal-title":"Glia"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib40","doi-asserted-by":"crossref","first-page":"6724","DOI":"10.1523\/JNEUROSCI.5520-03.2004","article-title":"Opposing extracellular signal-regulated kinase and Akt pathways control Schwann cell myelination","volume":"24","author":"Ogata","year":"2004","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib41","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1073\/pnas.96.4.1563","article-title":"Mutation of Pten\/Mmac1 in mice causes neoplasia in multiple organ systems","volume":"96","author":"Podsypanina","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib42","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1126\/science.1092089","article-title":"Regulation of cell migration by the C2 domain of the tumor suppressor PTEN","volume":"303","author":"Raftopoulou","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib43","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1007\/BF00691592","article-title":"Lhermitte-Duclos disease","volume":"59","author":"Reznik","year":"1983","journal-title":"Acta Neuropathol (Berl)"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib44","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.neuint.2005.08.014","article-title":"PTEN levels in Alzheimer\u2019s disease medial temporal cortex","volume":"48","author":"Rickle","year":"2006","journal-title":"Neurochem Int"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib45","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nrc1015","article-title":"Does the ribosome translate cancer?","volume":"3","author":"Ruggero","year":"2003","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib46","doi-asserted-by":"crossref","first-page":"7426","DOI":"10.1038\/sj.onc.1209098","article-title":"The Akt of translational control","volume":"24","author":"Ruggero","year":"2005","journal-title":"Oncogene"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib47","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1046\/j.1471-4159.2001.00453.x","article-title":"The inhibition of phosphatidylinositol-3-kinase induces neurite retraction and activates GSK3","volume":"78","author":"Sanchez","year":"2001","journal-title":"J Neurochem"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib48","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/S0092-8674(03)01021-3","article-title":"A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia","volume":"115","author":"Si","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib49","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/5007","article-title":"Generalized lacZ expression with the ROSA26 Cre reporter strain","volume":"21","author":"Soriano","year":"1999","journal-title":"Nat Genet"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib50","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/S0962-8924(03)00175-2","article-title":"PTEN: from pathology to biology","volume":"13","author":"Sulis","year":"2003","journal-title":"Trends Cell Biol"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib51","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/S0960-9822(07)00488-5","article-title":"High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice","volume":"8","author":"Suzuki","year":"1998","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib52","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S1074-7613(01)00134-0","article-title":"T cell-specific loss of Pten leads to defects in central and peripheral tolerance","volume":"14","author":"Suzuki","year":"2001","journal-title":"Immunity"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib53","doi-asserted-by":"crossref","first-page":"9760","DOI":"10.1523\/JNEUROSCI.1427-04.2004","article-title":"Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites","volume":"24","author":"Takei","year":"2004","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib54","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1073\/pnas.012605299","article-title":"A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus","volume":"99","author":"Tang","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib55","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1038\/nn1566","article-title":"Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2","volume":"8","author":"Tavazoie","year":"2005","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib56","doi-asserted-by":"crossref","first-page":"E59","DOI":"10.1371\/journal.pbio.0000059","article-title":"Pten dose dictates cancer progression in the prostate","volume":"1","author":"Trotman","year":"2003","journal-title":"PLoS Biol"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib57","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/nrc839","article-title":"The phosphatidylinositol 3-kinase AKT pathway in human cancer","volume":"2","author":"Vivanco","year":"2002","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib58","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S1535-6108(03)00215-0","article-title":"Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer","volume":"4","author":"Wang","year":"2003","journal-title":"Cancer Cell"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib59","doi-asserted-by":"crossref","first-page":"7429","DOI":"10.1158\/0008-5472.CAN-06-0712","article-title":"High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model","volume":"66","author":"Wei","year":"2006","journal-title":"Cancer Res"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib60","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S1535-6108(02)00029-6","article-title":"Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation","volume":"1","author":"Xiao","year":"2002","journal-title":"Cancer Cell"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib61","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/glia.20176","article-title":"Cell proliferation and replacement following contusive spinal cord injury","volume":"50","author":"Zai","year":"2005","journal-title":"Glia"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib62","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.nbd.2007.07.015","article-title":"Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex","volume":"28","author":"Zeng","year":"2007","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2007.10.048_bib63","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1002\/(SICI)1096-8628(19981204)80:4<399::AID-AJMG18>3.0.CO;2-O","article-title":"Germline PTEN mutation in a family with Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome","volume":"80","author":"Zori","year":"1998","journal-title":"Am J Med Genet"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452207012973?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452207012973?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,29]],"date-time":"2021-08-29T02:43:04Z","timestamp":1630204984000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452207012973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":63,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["S0306452207012973"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2007.10.048","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}