{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T23:57:47Z","timestamp":1789862267185,"version":"4.0.1"},"reference-count":71,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.1016\/j.neuroscience.2009.08.032","type":"journal-article","created":{"date-parts":[[2009,8,27]],"date-time":"2009-08-27T10:37:43Z","timestamp":1251369463000},"page":"1009-1018","source":"Crossref","is-referenced-by-count":75,"title":["Neurological autoimmunity targeting aquaporin-4"],"prefix":"10.1016","volume":"168","author":[{"given":"S.R.","family":"Hinson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"McKeon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.A.","family":"Lennon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2009.08.032_bib1","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1212\/01.WNL.0000115168.73299.88","article-title":"Devic disease and thymoma with anti-central nervous system and antithymus antibodies","volume":"62","author":"Antoine","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib2","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1017\/S0317167100053932","article-title":"Devic's neuromyelitis optica treated with intravenous gamma globulin (IVIG)","volume":"31","author":"Bakker","year":"2004","journal-title":"Can J Neurol Sci"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib3","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1111\/j.1471-4159.2007.04487.x","article-title":"Glutamate release from activated microglia requires the oxidative burst and lipid peroxidation","volume":"101","author":"Barger","year":"2007","journal-title":"J Neurochem"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib4","series-title":"Basic neuroscience with clinical applications","article-title":"Neuronal microenvironment","author":"Benarroch","year":"2006"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib5","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1002\/glia.440030503","article-title":"The excitatory neurotransmitter glutamate causes filopodia formation in cultured hippocampal astrocytes","volume":"3","author":"Cornell-Bell","year":"1990","journal-title":"Glia"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib6","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1111\/j.1471-4159.1990.tb01236.x","article-title":"An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro","volume":"54","author":"Dehouck","year":"1990","journal-title":"J Neurochem"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib7","first-page":"1033","article-title":"My\u00e9lite aigu\u00eb compliqu\u00e9e de n\u00e9vrite optique","volume":"8","author":"Devic","year":"1894","journal-title":"Bull Med"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib8a","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1177\/1352458508099139","article-title":"Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody","volume":"15","author":"Doi","year":"2009","journal-title":"Mult Scler"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib8","doi-asserted-by":"crossref","first-page":"6549","DOI":"10.4049\/jimmunol.178.10.6549","article-title":"System xc- and glutamate transporter inhibition mediates microglial toxicity to oligodendrocytes","volume":"178","author":"Domercq","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib9","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1136\/jnnp.2006.097972","article-title":"Devic's syndrome-like phenotype associated with thymoma and anti-CV2\/CRMP5 antibodies","volume":"78","author":"Ducray","year":"2007","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib10","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.sbi.2007.11.003","article-title":"Junction-forming aquaporins","volume":"18","author":"Engel","year":"2008","journal-title":"Curr Opin Struct Biol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib11","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1093\/rheumatology\/kei263","article-title":"Sustained improvement of a girl affected with Devic's disease over 2 years of mycophenolate mofetil treatment","volume":"45","author":"Falcini","year":"2006","journal-title":"Rheumatology (Oxford, England)"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib12","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1002\/eji.200635993","article-title":"Early type I interferon-mediated signals on B cells specifically enhance antiviral humoral responses","volume":"36","author":"Fink","year":"2006","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib13","doi-asserted-by":"crossref","first-page":"4328","DOI":"10.1073\/pnas.92.10.4328","article-title":"Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes","volume":"92","author":"Frigeri","year":"1995","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib14","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.1242\/jcs.108.9.2993","article-title":"Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues","volume":"108","author":"Frigeri","year":"1995","journal-title":"J Cell Sci"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib15","unstructured":"Gault F (1894) (De la neuromyelit\u00e9 optique aigu\u00eb. Th\u00e8se de Lyon serre 1.)"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib16","unstructured":"Hinson SR, McKeon A, Fryer JP, Apiwattanakul M, Lennon VA, Pittock SJ (in press) Complement-mediated injury to AQP4-expressing cells may predict attack severity in neuromyelitis optica. Arch Neurol, in press."},{"key":"10.1016\/j.neuroscience.2009.08.032_bib17","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1212\/01.WNL.0000289761.64862.ce","article-title":"Pathogenic potential of IgG binding to water channel extracellular domain in neuromyelitis optica","volume":"69","author":"Hinson","year":"2007","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib18","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1084\/jem.20081241","article-title":"Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2","volume":"205","author":"Hinson","year":"2008","journal-title":"J Exp Med"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib19","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.jmb.2005.10.081","article-title":"Implications of the aquaporin-4 structure on array formation and cell adhesion","volume":"355","author":"Hiroaki","year":"2006","journal-title":"J Mol Biol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib20","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1111\/j.1460-9568.2004.03689.x","article-title":"Astroglial processes show spontaneous motility at active synaptic terminals in situ","volume":"20","author":"Hirrlinger","year":"2004","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib21","first-page":"S244","article-title":"Treatment of neuromyelitis optica with mycophenolate: retrospective analysis of 25 cases","volume":"13","author":"Jacob","year":"2007","journal-title":"Mult Scler"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib22","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1001\/archneur.65.11.noc80069","article-title":"Treatment of neuromyelitis optica with rituximab: retrospective analysis of 25 patients","volume":"65","author":"Jacob","year":"2008","journal-title":"Arch Neurol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib23","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.ncl.2004.10.002","article-title":"Natural history of multiple sclerosis","volume":"23","author":"Kantarci","year":"2005","journal-title":"Neurol Clin"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib24","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1212\/WNL.58.1.143","article-title":"Plasma exchange for severe attacks of CNS demyelination: predictors of response","volume":"58","author":"Keegan","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib25","series-title":"Neuroimmunology in clinical practice","first-page":"210","article-title":"Paraneoplastic neurological autoimmunity","author":"Lachance","year":"2008"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib26","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1084\/jem.20050304","article-title":"IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel","volume":"202","author":"Lennon","year":"2005","journal-title":"J Exp Med"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib27","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1084\/jem.141.6.1365","article-title":"Experimental autoimmune myasthenia: a model of myasthenia gravis in rats and guinea pigs","volume":"141","author":"Lennon","year":"1975","journal-title":"J Exp Med"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib28","first-page":"A519","article-title":"Identification of a marker autoantibody of neuromyelitis optica","volume":"60","author":"Lennon","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib29","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1016\/S0140-6736(04)17551-X","article-title":"A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis","volume":"364","author":"Lennon","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib30","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1002\/1531-8249(200006)47:6<707::AID-ANA3>3.0.CO;2-Q","article-title":"Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination","volume":"47","author":"Lucchinetti","year":"2000","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib31","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1093\/brain\/awf151","article-title":"A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica","volume":"125","author":"Lucchinetti","year":"2002","journal-title":"Brain"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib32","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1212\/WNL.51.4.1219","article-title":"Devic's neuromyelitis optica: a prospective study of seven patients treated with prednisone and azathioprine","volume":"51","author":"Mandler","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib33","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1385\/NMM:3:2:65","article-title":"Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders","volume":"3","author":"Mattson","year":"2003","journal-title":"Neuromol Med"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib34","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1002\/glia.20524","article-title":"Expression and function of water channels (aquaporins) in migrating malignant astrocytes","volume":"55","author":"McCoy","year":"2007","journal-title":"Glia"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib35","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/nm0398-291","article-title":"Oligodendrocytes from forebrain are highly vulnerable to AMPA\/kainate receptor-mediated excitotoxicity","volume":"4","author":"McDonald","year":"1998","journal-title":"Nat Med"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib36","unstructured":"McKeon A, Fryer JP, Lennon VA, Apiwattanakul M, Hinson SR, Kryzer TJ, Lucchinetti CF, Weinshenker BG, Wingerchuk DM, Shuster EA, Pittock SJ (in press) Diagnosis of neuromyelitis spectrum disorders: comparative sensitivities and specificities of immunohistochemical and immunoprecipitation assays. Arch Neurol, in press."},{"key":"10.1016\/j.neuroscience.2009.08.032_bib37","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1002\/mus.21197","article-title":"Coexistence of myasthenia gravis and serological markers of neurological autoimmunity in neuromyelitis optica","volume":"39","author":"McKeon","year":"2009","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib38","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1212\/01.wnl.0000314832.24682.c6","article-title":"CNS aquaporin-4 autoimmunity in children","volume":"71","author":"McKeon","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib39","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1093\/brain\/awm047","article-title":"Loss of aquaporin 4 in lesions of neuromyelitis optica: distinction from multiple sclerosis","volume":"130","author":"Misu","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib40","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1212\/01.wnl.0000183151.19351.82","article-title":"Intractable hiccup and nausea with periaqueductal lesions in neuromyelitis optica","volume":"65","author":"Misu","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib41","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/0167-5699(96)20028-F","article-title":"Expression of complement in the brain: role in health and disease","volume":"17","author":"Morgan","year":"1996","journal-title":"Immunol Today"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib42","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1523\/JNEUROSCI.17-01-00171.1997","article-title":"Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain","volume":"17","author":"Nielsen","year":"1997","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib43","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1089\/0897715041269641","article-title":"The role of excitotoxicity in secondary mechanisms of spinal cord injury: a review with an emphasis on the implications for white matter degeneration","volume":"21","author":"Park","year":"2004","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib44","doi-asserted-by":"crossref","first-page":"3578","DOI":"10.4049\/jimmunol.152.7.3578","article-title":"Involvement of the cystine transport system xc-in the macrophage-induced glutamate-dependent cytotoxicity to neurons","volume":"152","author":"Piani","year":"1994","journal-title":"J Immunol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib45","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1001\/archneur.65.5.629","article-title":"Aquaporin-4 autoantibodies in a paraneoplastic context","volume":"65","author":"Pittock","year":"2008","journal-title":"Arch Neurol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib46","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1001\/archneurol.2007.17","article-title":"Neuromyelitis optica and non organ-specific autoimmunity","volume":"65","author":"Pittock","year":"2008","journal-title":"Arch Neurol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib47","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1001\/archneur.63.3.390","article-title":"Brain abnormalities in neuromyelitis optica","volume":"63","author":"Pittock","year":"2006","journal-title":"Arch Neurol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib48","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1001\/archneur.63.7.964","article-title":"Neuromyelitis optica brain lesions localized at sites of high aquaporin 4 expression","volume":"63","author":"Pittock","year":"2006","journal-title":"Arch Neurol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib49","first-page":"S41","article-title":"Autoimmune neurological accompaniments of neuromyelitis optica (NMO)","volume":"60","author":"Pittock","year":"2006","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib50","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/S1474-4422(07)70132-1","article-title":"Autoimmune disease in families with multiple sclerosis: a population-based study","volume":"6","author":"Ramagopalan","year":"2007","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib51","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.neuroscience.2004.06.076","article-title":"Freeze-fracture and immunogold analysis of aquaporin-4 (AQP4) square arrays, with models of AQP4 lattice assembly","volume":"129","author":"Rash","year":"2004","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib52","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1056\/NEJMra050541","article-title":"Antiinflammatory action of glucocorticoids\u2014new mechanisms for old drugs","volume":"353","author":"Rhen","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib53","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/S0166-2236(97)01139-9","article-title":"Reactive astrocytes: cellular and molecular cues to biological function","volume":"20","author":"Ridet","year":"1997","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib54","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1093\/brain\/awl371","article-title":"Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis","volume":"130","author":"Roemer","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib55","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0165-5728(96)00136-1","article-title":"Complement expression on astrocytes and astrocytoma cell lines: failure of complement regulation at the C3 level correlates with very low CD55 expression","volume":"71","author":"Spiller","year":"1996","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib56","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1620\/tjem.210.307","article-title":"Establishment of a new sensitive assay for anti-human aquaporin-4 antibody in neuromyelitis optica","volume":"210","author":"Takahashi","year":"2006","journal-title":"Tohoku J Exp Med"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib57","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.nbd.2005.06.017","article-title":"Increased expression and function of glutamate transporters in multiple sclerosis","volume":"21","author":"Vallejo-Illarramendi","year":"2006","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib58","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1152\/physrev.1998.78.1.99","article-title":"Glial calcium: homeostasis and signaling function","volume":"78","author":"Verkhratsky","year":"1998","journal-title":"Physiol Rev"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib59","doi-asserted-by":"crossref","first-page":"5730","DOI":"10.4049\/jimmunol.181.8.5730","article-title":"Functional consequences of neuromyelitis optica-IgG astrocyte interactions on blood-brain barrier permeability and granulocyte recruitment","volume":"181","author":"Vincent","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib60","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jns.2006.10.008","article-title":"Interferon beta-1b exacerbates multiple sclerosis with severe optic nerve and spinal cord demyelination","volume":"252","author":"Warabi","year":"2007","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib61","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1001\/archneur.65.7.913","article-title":"Aquaporin-4 antibodies in neuromyelitis optica and longitudinally extensive transverse myelitis","volume":"65","author":"Waters","year":"2008","journal-title":"Arch Neurol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib62","first-page":"A520","article-title":"A marker autoantibody discriminates neuromyelitis optica from multiple sclerosis","volume":"60","author":"Weinshenker","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib63","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1002\/ana.20770","article-title":"Neuromyelitis optica IgG predicts relapse after longitudinally extensive transverse myelitis","volume":"59","author":"Weinshenker","year":"2006","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib64","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1212\/WNL.53.5.1107","article-title":"The clinical course of neuromyelitis optica (Devic's syndrome)","volume":"53","author":"Wingerchuk","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib65","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/S1474-4422(07)70216-8","article-title":"The spectrum of neuromyelitis optica","volume":"6","author":"Wingerchuk","year":"2007","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib66","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1212\/01.wnl.0000216139.44259.74","article-title":"Revised diagnostic criteria for neuromyelitis optica","volume":"66","author":"Wingerchuk","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib67","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1212\/01.wnl.0000254502.87233.9a","article-title":"A secondary progressive clinical course is uncommon in neuromyelitis optica","volume":"68","author":"Wingerchuk","year":"2007","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib68","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0165-5728(93)90022-Q","article-title":"Expression of decay-accelerating factor (CD55), membrane cofactor protein (CD46) and CD59 in the human astroglioma cell line, D54-MG, and primary rat astrocytes","volume":"47","author":"Yang","year":"1993","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib69","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.neuron.2009.02.010","article-title":"Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1","volume":"61","author":"Yang","year":"2009","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2009.08.032_bib70","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1056\/NEJM199901213400311","article-title":"Mechanism of intravenous immune globulin therapy in antibody-mediated autoimmune diseases","volume":"340","author":"Yu","year":"1999","journal-title":"N Engl J Med"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452209013906?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452209013906?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T13:56:34Z","timestamp":1685109394000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452209013906"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":71,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["S0306452209013906"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2009.08.032","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2010,7]]}}}