{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T05:24:37Z","timestamp":1775625877839,"version":"3.50.1"},"reference-count":64,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1016\/j.neuroscience.2009.08.046","type":"journal-article","created":{"date-parts":[[2009,8,30]],"date-time":"2009-08-30T08:09:29Z","timestamp":1251619769000},"page":"415-423","source":"Crossref","is-referenced-by-count":23,"title":["Central noradrenergic depletion by DSP-4 prevents stress-induced memory impairments in the object recognition task"],"prefix":"10.1016","volume":"164","author":[{"given":"G.A.","family":"Scullion","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.A.","family":"Kendall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Sunter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.A.","family":"Marsden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.-C.","family":"Pardon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2009.08.046_bib1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/S0006-3223(98)00296-0","article-title":"Alpha-1 noradrenergic receptor stimulation impairs prefrontal cortical cognitive function","volume":"45","author":"Arnsten","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib2","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1523\/JNEUROSCI.01-08-00876.1981","article-title":"Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep\u2013waking cycle","volume":"1","author":"Aston-Jones","year":"1981","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib3","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/S0006-3223(99)00140-7","article-title":"Role of locus coeruleus in attention and behavioral flexibility","volume":"46","author":"Aston-Jones","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib4","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1007\/BF02244003","article-title":"DSP-4-induced depletion of brain norepinephrine produces opposite effects on exploratory behavior 3 and 14 days after treatment","volume":"100","author":"Berridge","year":"1990","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1365-2826.2005.01375.x","article-title":"Changes in hypothalamic-pituitary-adrenal function body temperature, body weight and food intake with repeated social stress exposure in rats","volume":"18","author":"Bhatnagar","year":"2006","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib6","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/S0006-3223(99)00138-9","article-title":"A role for norepinephrine in stress-induced cognitive deficits: alpha-1-adrenoceptor mediation in the prefrontal cortex","volume":"46","author":"Birnbaum","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib7","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1176\/ajp.150.7.1015","article-title":"Deficits in short-term memory in posttraumatic stress disorder","volume":"150","author":"Bremner","year":"1993","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib8","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/j.1460-9568.2005.03875.x","article-title":"New neurons in the dentate gyrus are involved in the expression of enhanced long-term memory following environmental enrichment","volume":"21","author":"Bruel-Jungerman","year":"2005","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jad.2007.06.006","article-title":"A review on cognitive impairments in depressive and anxiety disorders with a focus on young adults","volume":"106","author":"Castaneda","year":"2008","journal-title":"J Affect Disord"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib10","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1124\/jpet.301.1.187","article-title":"Effects of acute and subchronic administration of dexefaroxan an alpha(2)-adrenoceptor antagonist, on memory performance in young adult and aged rodents","volume":"301","author":"Chopin","year":"2002","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib11","doi-asserted-by":"crossref","first-page":"8853","DOI":"10.1523\/JNEUROSCI.20-23-08853.2000","article-title":"Impaired recognition memory in rats after damage to the hippocampus","volume":"20","author":"Clark","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib12","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/BF02805974","article-title":"Increased levels of extracellular noradrenaline in the frontal cortex of rats exposed to naturalistic environmental stimuli: modulation by acute systemic administration of diazepam or buspirone","volume":"127","author":"Dalley","year":"1996","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib13","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0166-2236(99)01438-1","article-title":"Stress and cognition: are corticosteroids good or bad guys?","volume":"22","author":"de Kloet","year":"1999","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib14","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/0306-4522(83)90277-4","article-title":"Alteration of central alpha 2- and beta-adrenergic receptors in the rat after DSP-4 a selective noradrenergic neurotoxin","volume":"9","author":"Dooley","year":"1983","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00439263","article-title":"Functional supersensitivity to adrenergic agonists in the rat after DSP-4 a selective noradrenergic neurotoxin","volume":"81","author":"Dooley","year":"1983","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib16","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0166-4328(88)90157-X","article-title":"A new one-trial test for neurobiological studies of memory in rats, 1: Behavioral data","volume":"31","author":"Ennaceur","year":"1988","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib17","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.1073\/pnas.77.5.3033","article-title":"Impulse activity of locus coeruleus neurons in awake rats and monkeys is a function of sensory stimulation and arousal","volume":"77","author":"Foote","year":"1980","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib18","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/1098-2396(20010301)39:3<213::AID-SYN1002>3.0.CO;2-W","article-title":"Biochemical effects of the monoamine neurotoxins DSP-4 and MDMA in specific brain regions of MAO-B-deficient mice","volume":"39","author":"Fornai","year":"2001","journal-title":"Synapse"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib19","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1002\/cne.903210309","article-title":"Restoration of ascending noradrenergic projections by residual locus coeruleus neurons: compensatory response to neurotoxin-induced cell death in the adult rat brain","volume":"321","author":"Fritschy","year":"1992","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib20","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0006-8993(90)90280-O","article-title":"Restoration of cholinomimetic activity by clonidine in cholinergic plus noradrenergic lesioned rats","volume":"507","author":"Haroutunian","year":"1990","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib21","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0006-8993(03)02677-5","article-title":"Effect of denervation of the locus coeruleus projections by DSP-4 treatment on [3H]-raclopride binding to dopamine D(2) receptors and D(2) receptor-G protein interaction in the rat striatum","volume":"976","author":"Harro","year":"2003","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib22","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0014-2999(93)90659-6","article-title":"Quantification of presynaptic alpha 2-adrenoceptors in rat brain after short-term DSP-4 lesioning","volume":"249","author":"Heal","year":"1993","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib23","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0166-4328(98)00134-X","article-title":"Stress impairs performance in spatial water maze learning tasks","volume":"100","author":"Holscher","year":"1999","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib24","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.brainres.2004.05.029","article-title":"Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes","volume":"1017","author":"Howlett","year":"2004","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib25","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s002130050569","article-title":"A partial noradrenergic lesion induced by DSP-4 increases extracellular noradrenaline concentration in rat frontal cortex: a microdialysis study in vivo","volume":"136","author":"Hughes","year":"1998","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib26","first-page":"380","article-title":"Phenytoin reverses the chronic stress-induced impairment of memory consolidation for water maze training and depression of LTP in rat hippocampal CA1 region but does not affect motor activity","volume":"24","author":"Hui","year":"2005","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib27","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0014-2999(81)90272-7","article-title":"DSP-4 (N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine)\u2014a useful denervation tool for central and peripheral noradrenaline neurons","volume":"72","author":"Jonsson","year":"1981","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib28","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1016\/0306-4522(82)90112-9","article-title":"Effects of the noradrenaline neurotoxin DSP-4 on the postnatal development of central noradrenaline neurons in the rat","volume":"7","author":"Jonsson","year":"1982","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib29","doi-asserted-by":"crossref","first-page":"52087","DOI":"10.1155\/2007\/52087","article-title":"The importance of cognitive phenotypes in experimental modeling of animal anxiety and depression","volume":"2007","author":"Kalueff","year":"2007","journal-title":"Neural Plast"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib30","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.nlm.2005.10.002","article-title":"Wistar rats show episodic-like memory for unique experiences","volume":"85","author":"Kart-Teke","year":"2006","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib31","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/PL00004942","article-title":"Overflow of noradrenaline and dopamine in frontal cortex after [N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine] (DSP-4) treatment: in vivo microdialysis study in anaesthetized rats","volume":"355","author":"Kask","year":"1997","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib32","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1006\/phrs.1999.0597","article-title":"Noradrenaline dopamine, serotonin: different effects of psychological stress on brain biogenic amines in mice and rats","volume":"41","author":"Konstandi","year":"2000","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib33","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/(SICI)1098-1063(1997)7:4<427::AID-HIPO8>3.0.CO;2-F","article-title":"Exposure to chronic psychosocial stress and corticosterone in the rat: effects on spatial discrimination learning and hippocampal protein kinase Cgamma immunoreactivity","volume":"7","author":"Krugers","year":"1997","journal-title":"Hippocampus"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib34","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s002130100702","article-title":"Effects of central noradrenaline depletion by the selective neurotoxin DSP-4 on the behaviour of the isolated rat in the elevated plus maze and water maze","volume":"155","author":"Lapiz","year":"2001","journal-title":"Psychopharmacology(Berl)"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib35","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.biopsych.2005.06.033","article-title":"Cortisol learning, memory, and attention in relation to smaller hippocampal volume in police officers with posttraumatic stress disorder","volume":"59","author":"Lindauer","year":"2006","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib36","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/0024-3205(85)90401-1","article-title":"Differential effects of DSP-4 administration on regional brain norepinephrine turnover in rats","volume":"37","author":"Logue","year":"1985","journal-title":"Life Sci"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib37","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.bandc.2007.02.007","article-title":"The effects of stress and stress hormones on human cognition: implications for the field of brain and cognition","volume":"65","author":"Lupien","year":"2007","journal-title":"Brain Cogn"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib38","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/S0006-3223(99)00139-0","article-title":"Local infusion of an alpha-1 adrenergic agonist into the prefrontal cortex impairs spatial working memory performance in monkeys","volume":"46","author":"Mao","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib39","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1111\/j.1749-6632.1999.tb08011.x","article-title":"Central noradrenergic neurotoxicity of DSP-4 in mice","volume":"890","author":"Marien","year":"1999","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib40","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1002\/hup.266","article-title":"Stress and hippocampal plasticity: implications for the pathophysiology of affective disorders","volume":"16","author":"McEwen","year":"2001","journal-title":"Hum Psychopharmacol"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib41","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0959-4388(95)80028-X","article-title":"Stress and cognitive function","volume":"5","author":"McEwen","year":"1995","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib42","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0014-2999(83)90103-6","article-title":"Identification of [3H]prazosin binding sites in crude membranes and isolated cells of brown adipose tissue as alpha 1-adrenergic receptors","volume":"92","author":"Mohell","year":"1983","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib43","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.bbr.2006.10.011","article-title":"Insulin protects against stress-induced impairments in water maze performance","volume":"176","author":"Moosavi","year":"2007","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib44","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/j.pnpbp.2005.08.007","article-title":"Role of brain norepinephrine in the behavioral response to stress","volume":"29","author":"Morilak","year":"2005","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib45","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1101\/lm.461407","article-title":"Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1\/2 in the prefrontal cortex","volume":"14","author":"Nagai","year":"2007","journal-title":"Learn Mem"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib46","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0014-2999(93)90514-I","article-title":"Impairment of working memory induced by scopolamine in rats with noradrenergic DSP-4 lesions","volume":"238","author":"Ohno","year":"1993","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib47","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/S0022-3565(25)38595-2","article-title":"Characterization of [3H]RX821002 binding to alpha-2 adrenergic receptor subtypes","volume":"268","author":"O'Rourke","year":"1994","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib48","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0306-4522(02)00364-0","article-title":"Stress reactivity of the brain noradrenergic system in three rat strains differing in their neuroendocrine and behavioral responses to stress: implications for susceptibility to stress-related neuropsychiatric disorders","volume":"115","author":"Pardon","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib49","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/j.1460-9568.2004.03549.x","article-title":"Repeated sensory contact with aggressive mice rapidly leads to an anticipatory increase in core body temperature and physical activity that precedes the onset of aversive responding","volume":"20","author":"Pardon","year":"2004","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib50","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.neuroscience.2005.01.033","article-title":"Social threat and novel cage stress-induced sustained extracellular-regulated kinase1\/2 (ERK1\/2) phosphorylation but differential modulation of brain-derived neurotrophic factor (BDNF) expression in the hippocampus of NMRI mice","volume":"132","author":"Pardon","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib50a","series-title":"The mouse brain in stereotaxic coordinates","author":"Paxinos","year":"2001"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib51","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1002\/hipo.20048","article-title":"BDNF protects against stress-induced impairments in spatial learning and memory and LTP","volume":"15","author":"Radecki","year":"2005","journal-title":"Hippocampus"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib52","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/S0006-3223(99)00127-4","article-title":"Role of norepinephrine in the pathophysiology and treatment of mood disorders","volume":"46","author":"Ressler","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib53","doi-asserted-by":"crossref","first-page":"13804","DOI":"10.1073\/pnas.0702753104","article-title":"Norepinephrine loss produces more profound motor deficits than MPTP treatment in mice","volume":"104","author":"Rommelfanger","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib54","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0306-4530(99)00058-X","article-title":"1999 Curt P. Richter award","volume":"25","author":"Roozendaal","year":"2000","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib55","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1111\/j.2042-7158.1976.tb04659.x","article-title":"On the long-lasting inhibitory effect of N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) on the active uptake of noradrenaline","volume":"28","author":"Ross","year":"1976","journal-title":"J Pharm Pharmacol"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib56","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0014-2999(90)90533-C","article-title":"Stress increases noradrenaline release in the rat frontal cortex: prevention by diazepam","volume":"176","author":"Rossetti","year":"1990","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib57","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S0006-8993(02)03007-X","article-title":"Colorectal distention induces hippocampal noradrenaline release in rats: an in vivo microdialysis study","volume":"947","author":"Saito","year":"2002","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib58","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/nrn2573","article-title":"The locus coeruleus and noradrenergic modulation of cognition","volume":"10","author":"Sara","year":"2009","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib59","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.neuroscience.2006.08.041","article-title":"The involvement of cholinergic and noradrenergic systems in behavioral recovery following oxotremorine treatment to chronically stressed rats","volume":"143","author":"Srikumar","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib60","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00702-003-0062-2","article-title":"Functional recovery of locus coeruleus noradrenergic neurons after DSP-4 lesion: effects on dopamine levels and neuroleptic induced-parkinsonian symptoms in rats","volume":"111","author":"Srinivasan","year":"2004","journal-title":"J Neural Transm"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib61","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1037\/0894-4105.16.1.5","article-title":"Attention learning, and memory performances and intellectual resources in Vietnam veterans: PTSD and no disorder comparisons","volume":"16","author":"Vasterling","year":"2002","journal-title":"Neuropsychology"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib62","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.neuroscience.2008.12.009","article-title":"Olfactory bulbectomy induces rapid and stable changes in basal and stress-induced locomotor activity heart rate and body temperature responses in the home cage","volume":"159","author":"Vinkers","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2009.08.046_bib63","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/BF01951769","article-title":"Stress-induced increase in noradrenaline release in the rat hypothalamus assessed by intracranial microdialysis","volume":"46","author":"Yokoo","year":"1990","journal-title":"Experientia"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452209013372?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452209013372?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T22:36:53Z","timestamp":1739313413000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452209013372"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":64,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["S0306452209013372"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2009.08.046","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}