{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T09:13:23Z","timestamp":1768641203852,"version":"3.49.0"},"reference-count":88,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ibroneuroscience.org","clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1016\/j.neuroscience.2010.10.031","type":"journal-article","created":{"date-parts":[[2010,10,21]],"date-time":"2010-10-21T09:26:23Z","timestamp":1287653183000},"page":"139-152","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":56,"special_numbering":"C","title":["Maternal exposure to the CB1 cannabinoid agonist WIN 55212\u20132 produces robust changes in motor function and intrinsic electrophysiological properties of cerebellar Purkinje neurons in rat offspring"],"prefix":"10.1016","volume":"172","author":[{"given":"M.","family":"Shabani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Hosseinmardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Haghani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Shaibani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Janahmadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2010.10.031_bib1","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0165-6147(92)90064-D","article-title":"Neurobiology of marijuana abuse","volume":"13","author":"Abood","year":"1992","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2008.01.011","article-title":"Inhibition of spontaneous neurotransmission in the nucleus of solitary tract of the rat by the cannabinoid agonist WIN 552122 is not via CB1 or CB2 receptors","volume":"1200","author":"Accorsi-Mendonca","year":"2008","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib3","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.neuroscience.2008.09.052","article-title":"T-type calcium channels mediate rebound firing in intact deep cerebellar neurons","volume":"158","author":"Alvi\u00f1a","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib4","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0301-0082(98)00087-2","article-title":"The effects of cannabinoids on the brain","volume":"58","author":"Ameri","year":"1999","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib5","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1093\/cercor\/bhi076","article-title":"Prenatal exposure to the CB1 receptor agonist WIN 55,2122 causes learning disruption associated with impaired cortical NMDA receptor function and emotional reactivity changes in rat offspring","volume":"15","author":"Antonelli","year":"2005","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib6","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1038\/nrn2148","article-title":"The action potential in mammalian central neurons","volume":"8","author":"Bean","year":"2007","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib7","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nrn2371","article-title":"Plasticity of intrinsic neuronal properties in CNS disorders","volume":"9","author":"Beck","year":"2008","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib8","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/toxsci\/68.1.109","article-title":"Neurobehavioral assessments of rats perinatally exposed to a commercial mixture of polychlorinated biphenyls","volume":"68","author":"Bushnell","year":"2002","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib9","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1152\/jn.1997.77.1.145","article-title":"Spatial distribution of synaptically activated sodium concentration changes in cerebellar Purkinje neurons","volume":"77","author":"Callaway","year":"1997","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib10","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1006\/exnr.1999.7171","article-title":"Tottering mouse motor dysfunction is abolished on the Purkinje cell degeneration (pcd) mutant background","volume":"160","author":"Campbell","year":"1999","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib11","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1152\/jn.1998.80.2.493","article-title":"Ionic mechanism of electroresponsiveness in cerebellar granule cells implicates the action of a persistent sodium current","volume":"80","author":"D'Angelo","year":"1998","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib11a","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/S0022-3565(25)09495-9","article-title":"Cannabinoids modulate voltage sensitive potassium A-current in hippocampal neurons via a cAMP-dependent process","volume":"273","author":"Deadwyler","year":"1995","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib12","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.neuroscience.2009.06.014","article-title":"Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease","volume":"163","author":"Dowie","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib13","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.pbb.2004.10.023","article-title":"Effects of the cannabinoid receptor agonist win 55,2122 on operant behavior and locomotor activity in rats","volume":"80","author":"Drews","year":"2005","journal-title":"Pharmacol Biochem Behav"},{"issue":"Pt 6","key":"10.1016\/j.neuroscience.2010.10.031_bib14","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1113\/jphysiol.2009.182196","article-title":"Reduced expression of the Ca(2+) transporter protein PMCA2 slows Ca(2+) dynamics in mouse cerebellar Purkinje neurons and alters the precision of motor coordination","volume":"588","author":"Empson","year":"2010","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib15","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1046\/j.1360-0443.2002.00103.x","article-title":"Cannabis use and psychosocial adjustment in adolescence and young adulthood","volume":"97","author":"Fergusson","year":"2002","journal-title":"Addiction"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib16","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/BF00501116","article-title":"Cannabinoids and hexobarbital induced loss of righting reflexes","volume":"283","author":"Fernandes","year":"1974","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib17","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1007\/s00702-009-0230-0","article-title":"Short- and long-term consequences of prenatal exposure to the cannabinoid agonist WIN55,2122 on rat glutamate transmission and cognitive functions","volume":"116","author":"Ferraro","year":"2009","journal-title":"J Neural Transm"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib18","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1093\/cercor\/11.8.728","article-title":"The cannabinoid receptor agonist WIN 55,212-2 regulates glutamate transmission in rat cerebral cortex: an in vivo and in vitro study","volume":"11","author":"Ferraro","year":"2001","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib19","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1152\/jn.01227.2005","article-title":"Cannabinoids modulate the P-type high-voltage-activated calcium currents in Purkinje neurons","volume":"96","author":"Fisyunov","year":"2006","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib20","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0031-6997(25)06893-0","article-title":"Toxicology of marihuana","volume":"23","author":"Forney","year":"1971","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib21","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0892-0362(92)90036-A","article-title":"A follow-up study of attentional behavior in 6-year-old children exposed prenatally to marihuana, cigarettes, and alcohol","volume":"14","author":"Fried","year":"1992","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib22","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0892-0362(98)00058-0","article-title":"Perinatal delta9-tetrahydrocannabinol exposure augmented the magnitude of motor inhibition caused by GABAB, but not GABAA, receptor agonists in adult rats","volume":"21","author":"Garcia-Gil","year":"1999","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib23","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1152\/jn.2001.85.1.468","article-title":"CB1 cannabinoid receptor inhibits synaptic release of glutamate in rat dorsolateral striatum","volume":"85","author":"Gerdeman","year":"2001","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib24","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0892-0362(00)00066-0","article-title":"Effects of prenatal marijuana exposure on child behavior problems at age 10","volume":"22","author":"Goldschmidt","year":"2000","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib25","unstructured":"Goonawardena AV, Riedel G, Hampson RE (in press) Cannabinoids alter spontaneous firing, bursting, and cell synchrony of hippocampal principal cells. Hippocampus, in press."},{"issue":"1\u20133","key":"10.1016\/j.neuroscience.2010.10.031_bib26","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ejphar.2010.05.031","article-title":"In vivo 4-aminopyridine treatment alters the neurotoxin 3-acetylpyridine-induced plastic changes in intrinsic electrophysiological properties of rat cerebellar Purkinje neurons","volume":"642","author":"Goudarzi","year":"2010","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib27","doi-asserted-by":"crossref","first-page":"807","DOI":"10.33549\/physiolres.931041","article-title":"Physiological role of dendrotoxin-sensitive K+ channels in the rat cerebellar Purkinje neurons","volume":"56","author":"Haghdoust","year":"2007","journal-title":"Physiol Res"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib28","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/S0896-6273(00)80379-7","article-title":"Tonic synaptic inhibition modulates neuronal output pattern and spatiotemporal synaptic integration","volume":"19","author":"H\u00e4usser","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib29","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0304-3940(95)11289-9","article-title":"Activation of inwardly rectifying potassium channels (GIRK1) by co-expressed rat brain cannabinoid receptors in Xenopus oocytes","volume":"186","author":"Henry","year":"1995","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib30","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0006-8993(91)90096-E","article-title":"Neuronal localization of cannabinoid receptors and second messengers in mutant mouse cerebellum","volume":"552","author":"Herkenham","year":"1991","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib31","doi-asserted-by":"crossref","first-page":"5276","DOI":"10.1073\/pnas.091096198","article-title":"Characterization of a high-voltage-activated IA current with a role in spike timing and locomotor pattern generation","volume":"98","author":"Hess","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib32","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1146\/annurev.pa.35.040195.003135","article-title":"Pharmacology of cannabinoid receptors","volume":"35","author":"Howlett","year":"1995","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib33","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.neubiorev.2005.04.005","article-title":"Maternal smoking, drinking or cannabis use during pregnancy and neurobehavioral and cognitive functioning in human offspring","volume":"30","author":"Huizink","year":"2006","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib34","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1100\/tsw.2002.139","article-title":"Cannabinoids on the brain","volume":"2","author":"Irving","year":"2002","journal-title":"ScientificWorldJournal"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib35","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.1152\/jn.01240.2007","article-title":"Low-voltage-activated potassium channels underlie the regulation of intrinsic firing properties of rat vestibular ganglion cells","volume":"100","author":"Iwasaki","year":"2008","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib36","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1523\/JNEUROSCI.17-01-00091.1997","article-title":"The role of synaptic and voltage-gated currents in the control of Purkinje cell spiking: a modeling study","volume":"17","author":"Jaeger","year":"1997","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib37","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.neuro.2009.02.014","article-title":"Co-treatment with riluzole, a neuroprotective drug, ameliorates the 3-acetylpyridine-induced neurotoxicity in cerebellar Purkinje neurons of rats: behavioural and electrophysiological evidence","volume":"30","author":"Janahmadi","year":"2009","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib38","series-title":"Neuromodulation: the biochemical control of neuronal excitability","first-page":"3","article-title":"What is neuromodulation?","author":"Kaczmareck","year":"1987"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib39","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1152\/physrev.00019.2008","article-title":"Endocannabinoid-mediated control of synaptic transmission","volume":"89","author":"Kano","year":"2009","journal-title":"Physiol Rev"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib40","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0031-6997(25)06898-X","article-title":"Doseresponse relationships to cannabis in human subjects","volume":"23","author":"Kiplinger","year":"1971","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib41","doi-asserted-by":"crossref","first-page":"RC174","DOI":"10.1523\/JNEUROSCI.21-20-j0005.2001","article-title":"Cerebellar depolarization-induced suppression of inhibition is mediated by endogenous cannabinoids","volume":"21","author":"Kreitzer","year":"2001","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib42","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1113\/jphysiol.1980.sp013358","article-title":"Electrophysiological properties of in vitro Purkinje cell dendrites in mammalian cerebellar slices","volume":"305","author":"Llin\u00e1s","year":"1980","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib43","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1523\/JNEUROSCI.11-07-01998.1991","article-title":"Multimodal characterization of population responses evoked by applied electric field in vitro: extracellular potential, magnetic evoked field, transmembrane potential, and current-source density analysis","volume":"11","author":"Lopez","year":"1991","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib44","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ceca.2009.07.007","article-title":"Dual modulation of CNS voltage-gated calcium channels by cannabinoids: focus on CB1 receptor-independent effects","volume":"46","author":"Lozovaya","year":"2009","journal-title":"Cell Calcium"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib45","doi-asserted-by":"crossref","first-page":"6552","DOI":"10.1523\/JNEUROSCI.15-10-06552.1995","article-title":"Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor","volume":"15","author":"Mackie","year":"1995","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib46","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1615\/CritRevNeurobiol.v11.i2-3.30","article-title":"Molecular aspects of cannabinoid receptors","volume":"11","author":"Matsuda","year":"1997","journal-title":"Crit Rev Neurobiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib47","doi-asserted-by":"crossref","first-page":"7677","DOI":"10.1523\/JNEUROSCI.23-20-07677.2003","article-title":"Motor dysfunction and altered synaptic transmission at the parallel fiber-Purkinje cell synapse in mice lacking potassium channels Kv3.1 and Kv3.3","volume":"23","author":"Matsukawa","year":"2003","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib48","doi-asserted-by":"crossref","first-page":"2590","DOI":"10.1152\/jn.00627.2006","article-title":"Climbing fiber discharge regulates cerebellar function by controlling the intrinsic characteristics of Purkinje cell output","volume":"97","author":"McKay","year":"2007","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib49","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1111\/j.1460-9568.2004.03539.x","article-title":"Kv3 K+ channels enable burst output in rat cerebellar Purkinje cells","volume":"20","author":"McKay","year":"2004","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib50","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.jphysparis.2008.10.011","article-title":"Regulation of somatic firing dynamics by backpropagating dendritic spikes","volume":"102","author":"Mehaffey","year":"2008","journal-title":"J Physiol Paris"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib51","doi-asserted-by":"crossref","first-page":"4915","DOI":"10.1073\/pnas.0537849100","article-title":"Prenatal exposure to a cannabinoid agonist produces memory deficits linked to dysfunction in hippocampal long-term potentiation and glutamate release","volume":"100","author":"Mereu","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib52","doi-asserted-by":"crossref","first-page":"10863","DOI":"10.1523\/JNEUROSCI.3436-05.2005","article-title":"A-type and T-type currents interact to produce a novel spike latency-voltage relationship in cerebellar stellate cells","volume":"25","author":"Molineux","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib53","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1097\/00008877-200509000-00015","article-title":"Long-term behavioural and neuroendocrine effects of perinatal activation or blockade of CB1 cannabinoid receptors","volume":"16","author":"Moreno","year":"2005","journal-title":"Behav Pharmacol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib54","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0091-3057(94)90110-4","article-title":"Motor behavior and nigrostriatal dopaminergic activity in adult rats perinatally exposed to cannabinoids","volume":"47","author":"Navarro","year":"1994","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib55","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.neuropharm.2007.07.003","article-title":"CB(1) receptor-dependent and - independent inhibition of excitatory postsynaptic currents in the hippocampus by WIN 55,212\u20132","volume":"54","author":"Nemeth","year":"2007","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib56","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1080\/14734220510007860","article-title":"Perinatal exposure to polychlorinated biphenyls differentially affects cerebellar development and motor functions in male and female rat neonates","volume":"4","author":"Nguon","year":"2005","journal-title":"Cerebellum"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib57","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.pharmthera.2005.09.009","article-title":"Receptor-independent actions of cannabinoids on cell membranes: focus on endocannabinoids","volume":"111","author":"Oz","year":"2006","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib58","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0022-3565(24)29579-3","article-title":"Cannabinoid CB(1) receptor agonists produce cerebellar dysfunction in mice","volume":"297","author":"Patel","year":"2001","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib59","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.ejphar.2008.02.099","article-title":"Cannabinoid modulation of executive functions","volume":"585","author":"Pattij","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib60","doi-asserted-by":"crossref","first-page":"4857","DOI":"10.1523\/JNEUROSCI.6065-09.2010","article-title":"Loss of beta-III spectrin leads to Purkinje cell dysfunction recapitulating the behavior and neuropathology of spinocerebellar ataxia type 5 in humans","volume":"30","author":"Perkins","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib61","doi-asserted-by":"crossref","first-page":"8268","DOI":"10.1523\/JNEUROSCI.1738-07.2007","article-title":"Homeostatic regulation of intrinsic excitability and synaptic transmission in a developing visual circuit","volume":"27","author":"Pratt","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib62","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s00213-006-0508-y","article-title":"The acute effects of cannabinoids on memory in humans: a review","volume":"88","author":"Ranganathan","year":"2006","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib63","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1006\/nbdi.1998.0217","article-title":"Role of the endogenous cannabinoid system in the regulation of motor activity","volume":"5","author":"Rodriguez de Fonseca","year":"1998","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib64","doi-asserted-by":"crossref","first-page":"3229","DOI":"10.1523\/JNEUROSCI.4333-05.2006","article-title":"Dopaminergic regulation of neuronal excitability through modulation of Ih in layer V entorhinal cortex","volume":"26","author":"Rosenkranz","year":"2006","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib65","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1113\/jphysiol.2002.022525","article-title":"A-type potassium currents active at subthreshold potentials in mouse cerebellar Purkinje cells","volume":"543","author":"Sacco","year":"2002","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib66","doi-asserted-by":"crossref","first-page":"C77","DOI":"10.1152\/ajpcell.00482.2004","article-title":"Activation of large-conductance, Ca2+-activated K+ channels by cannabinoids","volume":"290","author":"Sade","year":"2006","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib67","doi-asserted-by":"crossref","first-page":"9474","DOI":"10.1073\/pnas.0401702101","article-title":"Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency","volume":"101","author":"Sausbier","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib68","doi-asserted-by":"crossref","first-page":"9858","DOI":"10.1073\/pnas.0607037104","article-title":"Purkinje cell dysfunction and alteration of long-term synaptic plasticity in fetal alcohol syndrome","volume":"104","author":"Servais","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib69","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1523\/JNEUROSCI.20-01-00051.2000","article-title":"Cannabinoids decrease the K1 M-current in hippocampal CA1 neurons","volume":"20","author":"Schweitzer","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib70","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1172\/JCI200420216","article-title":"Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia","volume":"113","author":"Shakkottai","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib71","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1001\/archneurol.2009.212","article-title":"Physiologic alterations in ataxia: channeling changes into novel therapies","volume":"66","author":"Shakkottai","year":"2009","journal-title":"Arch Neurol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib72","doi-asserted-by":"crossref","first-page":"4145","DOI":"10.1523\/JNEUROSCI.20-11-04145.2000","article-title":"A-type K+ current mediated by the Kv4 channel regulates the generation of action potential in developing cerebellar granule cells","volume":"20","author":"Shibata","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib73","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1523\/JNEUROSCI.20-01-00114.2000","article-title":"Electrophysiological characterization of voltage-gated K+ currents in cerebellar basket and Purkinje cells: Kv1 and Kv3 channel subfamilies are present in basket cell nerve terminals","volume":"20","author":"Southan","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib74","doi-asserted-by":"crossref","first-page":"5786","DOI":"10.1073\/pnas.96.10.5786","article-title":"Altered gene expression in striatal projection neurons in CB1 cannabinoid receptor knockout mice","volume":"96","author":"Steiner","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib75","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0031-6997(25)00441-7","article-title":"Neuropharmacology of quinolinic and kynurenic acids","volume":"45","author":"Stone","year":"1993","journal-title":"Pharmacol Rev"},{"issue":"Pt 1","key":"10.1016\/j.neuroscience.2010.10.031_bib76","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1113\/jphysiol.2006.119362","article-title":"Depolarization-induced retrograde synaptic inhibition in the mouse cerebellar cortex is mediated by 2-arachidonoylglycerol","volume":"577","author":"Szabo","year":"2006","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib77","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1152\/jn.2002.88.1.534","article-title":"Cannabinoids depress inhibitory synaptic inputs received by layer 2\/3 pyramidal neurons of the neocortex","volume":"88","author":"Trettel","year":"2002","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib78","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0306-4522(97)00436-3","article-title":"Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system","volume":"83","author":"Tsou","year":"1998","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib78a","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1113\/expphysiol.2008.042416","article-title":"Perinatal and chronic hypothyroidism impair behavioural development in male and female rats","volume":"93","author":"van Wijk","year":"2008","journal-title":"Exp Physiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib79","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/nn1648","article-title":"Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia","volume":"9","author":"Walter","year":"2006","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib80","doi-asserted-by":"crossref","first-page":"11987","DOI":"10.1073\/pnas.0804350105","article-title":"Spinocerebellar ataxia type 6 knock in mice develop a progressive neuronal dysfunction with age-dependent accumulation of mutant CaV2.1 channels","volume":"105","author":"Watase","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"Pt 2","key":"10.1016\/j.neuroscience.2010.10.031_bib81","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1113\/jphysiol.2001.013136","article-title":"Membrane potential bistability is controlled by the hyperpolarization-activated current IH in rat cerebellar Purkinje neurons in vitro","volume":"539","author":"Williams","year":"2002","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib82","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1523\/JNEUROSCI.23-07-02600.2003","article-title":"Somatic and dendritic small-conductance calcium-activated potassium channels regulate the output of cerebellar Purkinje neurons","volume":"23","author":"Womack","year":"2003","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib83","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1523\/JNEUROSCI.0290-04.2004","article-title":"Dendritic control of spontaneous bursting in cerebellar Purkinje cells","volume":"24","author":"Womack","year":"2004","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib84","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1113\/jphysiol.1993.sp019643","article-title":"Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons","volume":"464","author":"Yoon","year":"1993","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib85","doi-asserted-by":"crossref","first-page":"9185","DOI":"10.1523\/JNEUROSCI.2858-05.2005","article-title":"Functional role of the fast transient outward K+ current IA in pyramidal neurons in (rat) primary visual cortex","volume":"25","author":"Yuan","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2010.10.031_bib86","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/nrn1248","article-title":"The other side of the engram: experience-driven changes in neuronal intrinsic excitability","volume":"4","author":"Zhang","year":"2003","journal-title":"Nat Rev Neurosci"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452210013618?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452210013618?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T18:00:44Z","timestamp":1740160844000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452210013618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":88,"alternative-id":["S0306452210013618"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2010.10.031","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2011,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal exposure to the CB1 cannabinoid agonist WIN 55212\u20132 produces robust changes in motor function and intrinsic electrophysiological properties of cerebellar Purkinje neurons in rat offspring","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2010.10.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 IBRO. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}