{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T20:11:46Z","timestamp":1773951106549,"version":"3.50.1"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"NIH","award":["AG5131"],"award-info":[{"award-number":["AG5131"]}]},{"name":"NIH","award":["DK057629"],"award-info":[{"award-number":["DK057629"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1016\/j.neuroscience.2011.11.032","type":"journal-article","created":{"date-parts":[[2011,12,12]],"date-time":"2011-12-12T09:59:50Z","timestamp":1323683990000},"page":"405-412","source":"Crossref","is-referenced-by-count":33,"special_numbering":"C","title":["Similar pattern of peripheral neuropathy in mouse models of type 1 diabetes and Alzheimer's disease"],"prefix":"10.1016","volume":"202","author":[{"given":"C.G.","family":"Jolivalt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.A.","family":"Calcutt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Masliah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2011.11.032_bib1","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.neulet.2008.06.079","article-title":"Dissociation of thermal hypoalgesia and epidermal denervation in streptozotocin-diabetic mice","volume":"442","author":"Beiswenger","year":"2008","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib2","first-page":"247","article-title":"Pain and dementia [Article in French]","volume":"4","author":"Belin","year":"2006","journal-title":"Psychol Neuropsychiatr Vieil"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib3","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S1474-4422(08)70021-8","article-title":"Cognition and diabetes: a lifespan perspective","volume":"7","author":"Biessels","year":"2008","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib4","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.2337\/diabetes.53.7.1824","article-title":"Direct insulin signaling of neurons reverses diabetic neuropathy","volume":"53","author":"Brussee","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib5","first-page":"55","article-title":"Modeling diabetic sensory neuropathy in rats","volume":"99","author":"Calcutt","year":"2004","journal-title":"Methods Mol Med"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib6","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1038\/sj.bjp.0701538","article-title":"Spinal pharmacology of tactile allodynia in diabetic rats","volume":"122","author":"Calcutt","year":"1997","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib7","doi-asserted-by":"crossref","first-page":"47","DOI":"10.2174\/138945008783431727","article-title":"Growth factors as therapeutics for diabetic neuropathy","volume":"9","author":"Calcutt","year":"2008","journal-title":"Curr Drug Targets"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib8","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-0270(94)90144-9","article-title":"Quantitative assessment of tactile allodynia in the rat paw","volume":"53","author":"Chaplan","year":"1994","journal-title":"J Neurosci Methods"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib9","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.neuroscience.2006.11.064","article-title":"Neurotrophic modulation of myelinated cutaneous innervation and mechanical sensory loss in diabetic mice","volume":"145","author":"Christianson","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib10","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.jpain.2003.07.002","article-title":"Beneficial actions of neurotrophin treatment on diabetes-induced hypoalgesia in mice","volume":"4","author":"Christianson","year":"2003","journal-title":"J Pain"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib11","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1007\/s00125-005-0023-4","article-title":"Cognitive decline and dementia in diabetes\u2014systematic overview of prospective observational studies","volume":"48","author":"Cukierman","year":"2005","journal-title":"Diabetologia"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib12","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1076\/chin.10.1.36.26241","article-title":"Neurocognitive correlates of type 1 diabetes mellitus in childhood","volume":"10","author":"Desrocher","year":"2004","journal-title":"Child Neuropsychol"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib13","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.nlm.2007.03.010","article-title":"Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice","volume":"88","author":"Dineley","year":"2007","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib14","doi-asserted-by":"crossref","first-page":"2923","DOI":"10.1002\/jnr.22445","article-title":"Amyloid-beta oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice","volume":"88","author":"Dineley","year":"2010","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib15","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1146\/annurev.pa.20.040180.002301","article-title":"Efficient analysis of experimental observations","volume":"20","author":"Dixon","year":"1980","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib16","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0006-8993(93)91496-F","article-title":"Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neurones","volume":"607","author":"Fernyhough","year":"1993","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib17","doi-asserted-by":"crossref","first-page":"2S","DOI":"10.1016\/S0002-9343(99)00007-8","article-title":"Diabetic neuropathy: scope of the syndrome","volume":"107","author":"Greene","year":"1999","journal-title":"Am J Med"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib18","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.nbd.2011.04.012","article-title":"Local insulin and the rapid regrowth of diabetic epidermal axons","volume":"43","author":"Guo","year":"2011","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib19","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.mcn.2004.08.009","article-title":"Insulin enhances mitochondrial inner membrane potential and increases ATP levels through phosphoinositide 3-kinase in adult sensory neurons","volume":"28","author":"Huang","year":"2005","journal-title":"Mol Cell Neurosci"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib20","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/341226a0","article-title":"Amyloid beta-protein deposition in tissues other than brain in Alzheimer's disease","volume":"341","author":"Joachim","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib21","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.pain.2008.07.007","article-title":"Early loss of peptidergic intraepidermal nerve fibers in an STZ-induced mouse model of insensate diabetic neuropathy","volume":"140","author":"Johnson","year":"2008","journal-title":"Pain"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib22","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.expneurol.2009.11.005","article-title":"Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice","volume":"223","author":"Jolivalt","year":"2010","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib23","doi-asserted-by":"crossref","first-page":"3265","DOI":"10.1002\/jnr.21787","article-title":"Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: parallels with Alzheimer's disease and correction by insulin","volume":"86","author":"Jolivalt","year":"2008","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib24","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.tibs.2003.12.004","article-title":"The glamour and gloom of glycogen synthase kinase-3","volume":"29","author":"Jope","year":"2004","journal-title":"Trends Biochem Sci"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib25","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0304-3940(99)00863-0","article-title":"Human amyloid-beta1-42 applied in vivo inhibits the fast axonal transport of proteins in the sciatic nerve of rat","volume":"278","author":"Kasa","year":"2000","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib26","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1093\/oxfordjournals.aje.a009106","article-title":"Risk of dementia among persons with diabetes mellitus: a population-based cohort study","volume":"145","author":"Leibson","year":"1997","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib27","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.neulet.2010.06.005","article-title":"Galantamine inhibits calpain-calcineurin signaling activated by beta-amyloid in human neuroblastoma SH-SY5Y cells","volume":"480","author":"Li","year":"2010","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib28","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.2337\/diabetes.55.04.06.db05-1323","article-title":"Brain magnetic resonance imaging correlates of impaired cognition in patients with type 2 diabetes","volume":"55","author":"Manschot","year":"2006","journal-title":"Diabetes"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib29","doi-asserted-by":"crossref","first-page":"E9","DOI":"10.1542\/peds.109.1.e9","article-title":"Effects of diabetes on learning in children","volume":"109","author":"McCarthy","year":"2002","journal-title":"Pediatrics"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib30","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.tig.2006.03.007","article-title":"A decade of modeling Alzheimer's disease in transgenic mice","volume":"22","author":"McGowan","year":"2006","journal-title":"Trends Genet"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib31","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.2337\/db09-0594","article-title":"Caveolin-1 and altered neuregulin signaling contribute to the pathophysiological progression of diabetic peripheral neuropathy","volume":"58","author":"McGuire","year":"2009","journal-title":"Diabetes"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib32","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.nurt.2009.07.004","article-title":"Diabetic painful and insensate neuropathy: pathogenesis and potential treatments","volume":"6","author":"Obrosova","year":"2009","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib33","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1007\/s001250050588","article-title":"Association of diabetes mellitus and dementia: the Rotterdam study","volume":"39","author":"Ott","year":"1996","journal-title":"Diabetologia"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib34","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S0197-0186(02)00014-1","article-title":"Presenilin-1 and the amyloid precursor protein are transported bidirectionally in the sciatic nerve of adult rat","volume":"41","author":"Papp","year":"2002","journal-title":"Neurochem Int"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib35","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.nbd.2004.08.003","article-title":"Insulin resistance contributes to aberrant stress responses in the Tg2576 mouse model of Alzheimer's disease","volume":"17","author":"Pedersen","year":"2004","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib36","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.2337\/diabetes.51.4.1256","article-title":"Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: the Honolulu-Asia aging study","volume":"51","author":"Peila","year":"2002","journal-title":"Diabetes"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib37","doi-asserted-by":"crossref","first-page":"16","DOI":"10.2337\/diacare.13.1.16","article-title":"Relationship between hyperglycemia and cognitive function in older NIDDM patients","volume":"13","author":"Reaven","year":"1990","journal-title":"Diabetes Care"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib38","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1002\/jnr.1247","article-title":"Early formation of mature amyloid-beta proteins deposits in a mutant APP transgenic model depends on levels of Abeta(1-42)","volume":"66","author":"Rockenstein","year":"2001","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib39","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1007\/s00125-009-1393-9","article-title":"Glucose metabolism and the risk of Alzheimer's disease and dementia: a population-based 12 year follow-up study in 71-year-old men","volume":"52","author":"R\u00f6nnemaa","year":"2009","journal-title":"Diabetologia"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib40","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1542\/peds.75.5.921","article-title":"Cognitive deficits in adolescents who developed diabetes early in life","volume":"75","author":"Ryan","year":"1985","journal-title":"Pediatrics"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib41","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1080\/01688639308402589","article-title":"Effects of insulin-dependent diabetes on learning and memory efficiency in adults","volume":"15","author":"Ryan","year":"1993","journal-title":"J Clin Exp Neuropsychol"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib42","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1365-2648.2005.03577.x","article-title":"Pain in Alzheimer's disease: nursing assistants' and patients' evaluations","volume":"52","author":"Scherder","year":"2005","journal-title":"J Adv Nurs"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib43","first-page":"116","article-title":"Chronic pain in dementia and in disorders with a high risk for congnitive impairment [Article in Dutch]","volume":"36","author":"Scherder","year":"2005","journal-title":"Tijdschr Gerontol Geriatr"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib44","doi-asserted-by":"crossref","first-page":"3136","DOI":"10.1523\/JNEUROSCI.13-07-03136.1993","article-title":"Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system","volume":"13","author":"Sisodia","year":"1993","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib45","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1046\/j.1529-8027.2002.02005.x","article-title":"Expression and localization of insulin receptor in rat dorsal root ganglion and spinal cord","volume":"7","author":"Sugimoto","year":"2002","journal-title":"J Peripher Nerv Syst"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib46","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1002\/1520-7560(200009\/10)16:5<354::AID-DMRR149>3.0.CO;2-H","article-title":"Insulin receptor in rat peripheral nerve: its localization and alternatively spliced isoforms","volume":"16","author":"Sugimoto","year":"2000","journal-title":"Diabetes Metab Res Rev"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib47","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0304-3940(95)11964-X","article-title":"Amyloid beta peptide induces cytoplasmic accumulation of amyloid protein precursor via tau protein kinase I\/glycogen synthase kinase-3 beta in rat hippocampal neurons","volume":"198","author":"Takashima","year":"1995","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib48","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1177\/0891988706291079","article-title":"Alzheimer's disease and the aging brain","volume":"19","author":"Terry","year":"2006","journal-title":"J Geriatr Psychiatry Neurol"},{"issue":"Suppl 2","key":"10.1016\/j.neuroscience.2011.11.032_bib49","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.2337\/diab.46.2.S54","article-title":"Classification, differential diagnosis, and staging of diabetic peripheral neuropathy","volume":"46","author":"Thomas","year":"1997","journal-title":"Diabetes"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib50","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1744-8069-6-16","article-title":"Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain","volume":"6","author":"Toth","year":"2010","journal-title":"Mol Pain"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib51","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.nbd.2009.09.008","article-title":"Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus","volume":"37","author":"Valente","year":"2010","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib52","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1192\/bjp.bp.109.067942","article-title":"Risk of developing dementia in people with diabetes and mild cognitive impairment","volume":"196","author":"Velayudhan","year":"2010","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib53","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s00125-009-1323-x","article-title":"Uncontrolled diabetes increases the risk of Alzheimer's disease: a population-based cohort study","volume":"52","author":"Xu","year":"2009","journal-title":"Diabetologia"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib54","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0301-0082(03)00034-0","article-title":"Diabetic neuropathy and nerve regeneration","volume":"69","author":"Yasuda","year":"2003","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.neuroscience.2011.11.032_bib55","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1212\/WNL.45.6.1161","article-title":"Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: the Hisayama study","volume":"45","author":"Yoshitake","year":"1995","journal-title":"Neurology"}],"updated-by":[{"DOI":"10.1016\/j.neuroscience.2025.04.017","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T00:00:00Z","timestamp":1748044800000}}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452211012991?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452211012991?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T19:09:50Z","timestamp":1713208190000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452211012991"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":55,"alternative-id":["S0306452211012991"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2011.11.032","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}