{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:59:37Z","timestamp":1788872377580,"version":"build-2803163510"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"NHMRC Biomedical Training and the University of South Australia"},{"name":"Australian Research Council Future"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1016\/j.neuroscience.2012.09.034","type":"journal-article","created":{"date-parts":[[2012,9,25]],"date-time":"2012-09-25T16:02:47Z","timestamp":1348588967000},"page":"110-118","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Exocytosis is impaired in mucopolysaccharidosis IIIA mouse chromaffin cells"],"prefix":"10.1016","volume":"227","author":[{"given":"D.J.","family":"Keating","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"Winter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.M.","family":"Hemsley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.D.","family":"Mackenzie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.H.","family":"Teo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.J.","family":"Hopwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.A.","family":"Brooks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.J.","family":"Parkinson-Lawrence","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2012.09.034_b0005","doi-asserted-by":"crossref","first-page":"7334","DOI":"10.1523\/JNEUROSCI.20-19-07334.2000","article-title":"Biogenesis of regulated exocytotic carriers in neuroendocrine cells","volume":"20","author":"Benjamin","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0010","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1093\/glycob\/11.1.99","article-title":"A novel missense mutation in lysosomal sulfamidase is the basis of MPS IIIA in a spontaneous mouse mutant","volume":"11","author":"Bhattacharyya","year":"2001","journal-title":"Glycobiology"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0015","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1093\/glycob\/9.12.1389","article-title":"A mouse model for mucopolysaccharidosis type IIIA (Sanfilippo syndrome)","volume":"9","author":"Bhaumik","year":"1999","journal-title":"Glycobiology"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0020","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/(SICI)1521-1878(199804)20:4<328::AID-BIES9>3.0.CO;2-L","article-title":"Analysis of regulated exocytosis in adrenal chromaffin cells: insights into NSF\/SNAP\/SNARE function","volume":"20","author":"Burgoyne","year":"1998","journal-title":"Bioassays"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0025","first-page":"1","article-title":"Lipid dynamics in exocytosis","author":"Chasserot-Golaz","year":"2010","journal-title":"Cell Mol Neurobiol"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0030","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0165-0270(00)00359-9","article-title":"Amperometric analysis of exocytosis at chromaffin cells from genetically distinct mice","volume":"30","author":"Colliver","year":"2001","journal-title":"J Neurosci Methods"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2006.05.079","article-title":"Characterization of a C57BL\/6 congenic mouse strain of mucopolysaccharidosis type IIIA","volume":"1104","author":"Crawley","year":"2006","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0040","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1083\/jcb.200412001","article-title":"Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer","volume":"170","author":"Dermaut","year":"2005","journal-title":"J Cell Biol"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0045","first-page":"151","article-title":"Electron microscopy in human medicine","volume":"Vol. 2","author":"Dustin","year":"1978"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0050","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.ymgme.2004.07.016","article-title":"Purification and characterization of recombinant murine sulfamidase","volume":"83","author":"Gliddon","year":"2004","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0055","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.bbr.2004.08.019","article-title":"Development of motor deficits in a murine model of mucopolysaccharidosis type IIIA (MPS-IIIA)","volume":"158","author":"Hemsley","year":"2005","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0060","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1111\/j.1601-183X.2008.00413.x","article-title":"Effect of high dose, repeated intra-cerebrospinal fluid injection of sulphamidase on neuropathology in mucopolysaccharidosis type IIIA mice","volume":"7","author":"Hemsley","year":"2008","journal-title":"Genes Brain Behav"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0065","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1111\/j.1460-9568.2009.06666.x","article-title":"Examination of intravenous and intra-CSF protein delivery for treatment of neurological disease","volume":"29","author":"Hemsley","year":"2009","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0070","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1194\/jlr.M500482-JLR200","article-title":"The Niemann\u2013Pick C1 protein in recycling endosomes of presynaptic nerve terminals","volume":"47","author":"Karten","year":"2006","journal-title":"J Lipid Res"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0075","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1093\/hmg\/ddm374","article-title":"DSCR1\/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: implications for Down syndrome and Alzheimer\u2019s disease","volume":"17","author":"Keating","year":"2008","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0080","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.ymgme.2005.09.026","article-title":"Validation of a heparan sulfate-derived disaccharide as a marker of accumulation in murine mucopolysaccharidosis type IIIA","volume":"87","author":"King","year":"2006","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0085","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ceca.2009.12.007","article-title":"Aberrant Ca2+ handling in lysosomal storage disorders","volume":"47","author":"Kiselyov","year":"2010","journal-title":"Cell Calcium"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0090","series-title":"Handbook of experimental pharmacology","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/978-3-540-74805-2_5","article-title":"Pharmacology of neurotransmitter release","author":"Lang","year":"2008"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0095","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.ymgme.2006.05.016","article-title":"Lysosomal exocytosis is impaired in mucolipidosis type IV","volume":"89","author":"LaPlante","year":"2006","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0100","doi-asserted-by":"crossref","first-page":"3351","DOI":"10.1210\/en.2011-0124","article-title":"Cholesterol elevation impairs glucose-stimulated Ca (2+) signalling in mouse pancreatic \u03b2-cells","volume":"152","author":"Lee","year":"2011","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0105","doi-asserted-by":"crossref","first-page":"10587","DOI":"10.1523\/JNEUROSCI.3750-08.2008","article-title":"Role of the vesicular chloride transporter ClC-3 in neuroendocrine tissue","volume":"28","author":"Maritzen","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0115","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00418-008-0377-z","article-title":"Discovery and progress in our understanding of the regulated secretory pathway in neuroendocrine cells","volume":"129","author":"Morvan","year":"2008","journal-title":"Histochem Cell Biol"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0120","series-title":"The metabolic and molecular bases of inherited diseases","first-page":"3421","author":"Neufeld","year":"2001"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0125","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1083\/jcb.17.1.208","article-title":"The use of lead citrate at high pH as an electron-opaque stain in electron microscopy","volume":"17","author":"Reynolds","year":"1963","journal-title":"J Cell Biol"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0130","doi-asserted-by":"crossref","first-page":"17215","DOI":"10.1016\/S0021-9258(17)32542-5","article-title":"Zones of exocytotic release on bovine adrenal medullary cells in culture","volume":"269","author":"Schroeder","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0135","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1083\/jcb.31.2.319","article-title":"Lysosome function in the regulation of the secretory process in cells of the anterior pituitary gland","volume":"31","author":"Smith","year":"1966","journal-title":"J Cell Biol"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fnsyn.2011.00002","article-title":"Vesicle pools: lessons from adrenal chromaffin cells","volume":"3","author":"Stevens","year":"2011","journal-title":"Front Syn Neurosci"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0145","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1146\/annurev.neuro.26.041002.131412","article-title":"The synaptic vesicle cycle","volume":"27","author":"S\u00fcdhof","year":"2004","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1101\/cshperspect.a005637","article-title":"Synaptic vesicle exocytosis","volume":"3","author":"S\u00fcdhof","year":"2011","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0155","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1096\/fasebj.8.2.7907072","article-title":"A role for synaptic vesicles in non-neuronal cells: clues from pancreatic \u03b2-cells and from chromaffin cells","volume":"8","author":"Thomas-Reetz","year":"1994","journal-title":"FASEB J"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0160","doi-asserted-by":"crossref","first-page":"4705","DOI":"10.1210\/en.2010-0623","article-title":"Cholesterol biosynthesis pathway intermediates and inhibitors regulate glucose-stimulated insulin secretion and secretory granule formation in pancreatic {beta}-cells","volume":"151","author":"Tsuchiya","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0165","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.nbd.2005.03.012","article-title":"Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice","volume":"20","author":"Virmani","year":"2005","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0170","doi-asserted-by":"crossref","first-page":"3904","DOI":"10.1523\/JNEUROSCI.4000-09.2010","article-title":"Influence of cholesterol on catecholamine release from the fusion pore of large dense core chromaffin granules","volume":"30","author":"Wang","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0175","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.neuroscience.2010.02.033","article-title":"Defects of synaptic vesicle turnover at excitatory and inhibitory synapses in Niemann\u2013Pick C1-deficient neurons","volume":"167","author":"Xu","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0180","doi-asserted-by":"crossref","first-page":"3281","DOI":"10.1093\/hmg\/ddn224","article-title":"Mice deficient for the chromosome 21 ortholog Itsn1 exhibit vesicle-trafficking abnormalities","volume":"17","author":"Yu","year":"2008","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2012.09.034_b0185","doi-asserted-by":"crossref","first-page":"2524","DOI":"10.1016\/j.bpj.2010.02.043","article-title":"Membrane bending energy and fusion pore kinetics in Ca (2+)-triggered exocytosis","volume":"98","author":"Zhang","year":"2010","journal-title":"Biophys J"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452212009529?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452212009529?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,1,29]],"date-time":"2022-01-29T10:35:31Z","timestamp":1643452531000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452212009529"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":36,"alternative-id":["S0306452212009529"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2012.09.034","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}