{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T13:25:14Z","timestamp":1791984314499,"version":"4.4.0"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"NIH-NIDA","award":["P60-DA05130"],"award-info":[{"award-number":["P60-DA05130"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1016\/j.neuroscience.2012.12.071","type":"journal-article","created":{"date-parts":[[2013,1,18]],"date-time":"2013-01-18T21:30:38Z","timestamp":1358544638000},"page":"220-232","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Proopiomelanocortin (POMC) expression and conditioned place aversion during protracted withdrawal from chronic intermittent escalating-dose heroin in POMC-EGFP promoter transgenic mice"],"prefix":"10.1016","volume":"236","author":[{"given":"K.","family":"Niikura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.J.","family":"Kreek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2012.12.071_b0005","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0893-133X(99)00133-5","article-title":"Persistent increase in the motivation to take heroin in rats with a history of drug escalation","volume":"22","author":"Ahmed","year":"2000","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0010","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1042\/bst0310147","article-title":"Chemical signalling in mice","volume":"31","author":"Beauchamp","year":"2003","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0015","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/0006-8993(90)90066-K","article-title":"Effects of morphine treatment on pro-opiomelanocortin systems in rat brain","volume":"519","author":"Bronstein","year":"1990","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0020","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/cne.903240203","article-title":"Connections of the posterior nucleus of the amygdala","volume":"324","author":"Canteras","year":"1992","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0025","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/cne.903600203","article-title":"Organization of projections from the medial nucleus of the amygdala: a PHAL study in the rat","volume":"360","author":"Canteras","year":"1995","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0030","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1038\/sj.npp.1301008","article-title":"Unlimited access to heroin self-administration: independent motivational markers of opiate dependence","volume":"31","author":"Chen","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0035","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/0306-4522(94)00532-A","article-title":"Regional changes in c-fos expression in the basal forebrain and brainstem during adaptation to repeated stress: correlations with cardiovascular, hypothermic and endocrine responses","volume":"64","author":"Chen","year":"1995","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0040","doi-asserted-by":"crossref","first-page":"4670","DOI":"10.1073\/pnas.0700670104","article-title":"Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female mice","volume":"104","author":"Choleris","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0045","doi-asserted-by":"crossref","first-page":"6783","DOI":"10.1016\/S0021-9258(18)34498-3","article-title":"Detection and quantitation of pro-opiomelanocortin mRNA in pituitary and brain tissues from different species","volume":"257","author":"Civelli","year":"1982","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0050","doi-asserted-by":"crossref","first-page":"18649","DOI":"10.1073\/pnas.0506999102","article-title":"The corticotropin-releasing factor receptor-1 pathway mediates the negative affective states of opiate withdrawal","volume":"102","author":"Contarino","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0055","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/0091-3057(89)90074-9","article-title":"Heroin self-administration by rats: influence of dose and physical dependence","volume":"32","author":"Dai","year":"1989","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0060","doi-asserted-by":"crossref","first-page":"R131","DOI":"10.1016\/S0960-9822(00)00345-6","article-title":"The amygdala","volume":"10","author":"Davis","year":"2000","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0065","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1046\/j.1460-9568.1999.00645.x","article-title":"Neuroendocrine responses to an emotional stressor: evidence for involvement of the medial but not the central amygdala","volume":"11","author":"Dayas","year":"1999","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0070","first-page":"122","article-title":"Narcotic blockade\u2013a medical technique for stopping heroin use by addicts","volume":"79","author":"Dole","year":"1966","journal-title":"Trans Assoc Am Phys"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0075","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/nrn1140","article-title":"Molecular detection of pheromone signals in mammals: from genes to behaviour","volume":"4","author":"Dulac","year":"2003","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0080","doi-asserted-by":"crossref","first-page":"7579","DOI":"10.1073\/pnas.120552597","article-title":"Opiates inhibit neurogenesis in the adult rat hippocampus","volume":"97","author":"Eisch","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0085","doi-asserted-by":"crossref","first-page":"8278","DOI":"10.1523\/JNEUROSCI.21-20-08278.2001","article-title":"Oxytocin in the medial amygdala is essential for social recognition in the mouse","volume":"21","author":"Ferguson","year":"2001","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0090","series-title":"The mouse brain in stereotaxic coordinates","author":"Franklin","year":"1997"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0095","first-page":"536","article-title":"Development and maintenance of morphine tolerance and dependence in the rat by scheduled access to morphine drinking solutions","volume":"205","author":"Gellert","year":"1978","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0100","doi-asserted-by":"crossref","first-page":"4475","DOI":"10.1046\/j.0953-816X.2000.01334.x","article-title":"Mapping of c-fos gene expression in the brain during morphine dependence and precipitated withdrawal, and phenotypic identification of the striatal neurons involved","volume":"12","author":"Georges","year":"2000","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0105","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.expneurol.2008.04.045","article-title":"Conditional deletion of the NMDA-NR1 receptor subunit gene in the central nucleus of the amygdala inhibits naloxone-induced conditioned place aversion in morphine-dependent mice","volume":"213","author":"Glass","year":"2008","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0110","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1038\/nature02033","article-title":"A gene expression atlas of the central nervous system based on bacterial artificial chromosomes","volume":"425","author":"Gong","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0115","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1101\/lm.37601","article-title":"Contextual and auditory fear conditioning are mediated by the lateral, basal, and central amygdaloid nuclei in rats","volume":"8","author":"Goosens","year":"2001","journal-title":"Learn Mem"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0120","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S0196-9781(98)00036-9","article-title":"Detection of pro-opiomelanocortin mRNA in human and rat caudal medulla by RT-PCR","volume":"19","author":"Grauerholz","year":"1998","journal-title":"Peptides"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0125","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/0006-8993(91)90836-K","article-title":"Beta-endorphin and methionine\u2013enkephalin levels in discrete brain regions, spinal cord, pituitary gland and plasma of morphine tolerant-dependent and abstinent rats","volume":"553","author":"Gudehithlu","year":"1991","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0130","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.brainresbull.2006.09.001","article-title":"Exposure to high- and low-light conditions in an open-field test of anxiety increases c-Fos expression in specific subdivisions of the rat basolateral amygdaloid complex","volume":"71","author":"Hale","year":"2006","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0135","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.yfrne.2003.07.001","article-title":"Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness","volume":"24","author":"Herman","year":"2003","journal-title":"Front Neuroendocrinol"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0140","first-page":"428","article-title":"Withdrawal-induced c-Fos expression in the rat centromedial amygdala 24 h following a single morphine exposure","volume":"175","author":"Jin","year":"2004","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0145","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1037\/0735-7036.122.2.121","article-title":"Memory for individuals: hamsters (Mesocricetus auratus) require contact to develop multicomponent representations (concepts) of others","volume":"122","author":"Johnston","year":"2008","journal-title":"J Comp Psychol"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0150","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1111\/j.1460-9568.2009.06638.x","article-title":"A direct main olfactory bulb projection to the \u2018vomeronasal\u2019 amygdala in female mice selectively responds to volatile pheromones from males","volume":"29","author":"Kang","year":"2009","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0155","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/(SICI)1098-1063(1999)9:3<321::AID-HIPO11>3.0.CO;2-C","article-title":"Experience-dependent regulation of adult hippocampal neurogenesis: effects of long-term stimulation and stimulus withdrawal","volume":"9","author":"Kempermann","year":"1999","journal-title":"Hippocampus"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0160","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1369-1600.2004.tb00534.x","article-title":"Neuroendocrine pathways of addictive behaviour","volume":"9","author":"Kiefer","year":"2004","journal-title":"Addict Biol"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0165","first-page":"232","article-title":"Opiates, opioids and addiction","volume":"1","author":"Kreek","year":"1996","journal-title":"Mol Psychiatry"},{"issue":"Suppl 1","key":"10.1016\/j.neuroscience.2012.12.071_b0170","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.neuropharm.2008.07.042","article-title":"Bidirectional translational research: progress in understanding addictive diseases","volume":"56","author":"Kreek","year":"2009","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0175","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/syn.10173","article-title":"Subject-regulated dosing alters morphine self-administration behavior and morphine-stimulated [35S]GTPgammaS binding","volume":"47","author":"Kruzich","year":"2003","journal-title":"Synapse"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0180","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1523\/JNEUROSCI.16-06-02027.1996","article-title":"Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation","volume":"16","author":"Kuhn","year":"1996","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0091-3057(00)00442-1","article-title":"Quantifiable dose-dependent withdrawal after morphine discontinuation in a rat model","volume":"68","author":"Langerman","year":"2001","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0190","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1002\/(SICI)1096-9861(19980406)393:2<244::AID-CNE8>3.0.CO;2-2","article-title":"Hypothalamic effector neurons and extended circuitries activated in \u201cneurogenic\u201d stress: a comparison of footshock effects exerted acutely, chronically, and in animals with controlled glucocorticoid levels","volume":"393","author":"Li","year":"1998","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0195","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1038\/nn1383","article-title":"Central amygdala ERK signaling pathway is critical to incubation of cocaine craving","volume":"8","author":"Lu","year":"2005","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0200","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.neuroscience.2010.10.033","article-title":"Amygdalar roles during exposure to a live predator and to a predator-associated context","volume":"172","author":"Martinez","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0205","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1101\/gad.13.13.1647","article-title":"NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus","volume":"13","author":"Miyata","year":"1999","journal-title":"Genes Dev"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0210","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/BF02896854","article-title":"Down-regulation of proopiomelanocortin synthesis and beta-endorphin utilization in hypothalamus of morphine-tolerant rats","volume":"1","author":"Mocchetti","year":"1989","journal-title":"J Mol Neurosci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0215","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/j.1749-6632.1999.tb09271.x","article-title":"The medial extended amygdala in male reproductive behavior. A node in the mammalian social behavior network","volume":"877","author":"Newman","year":"1999","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0220","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.neulet.2008.02.059","article-title":"Direct evidence for the involvement of endogenous beta-endorphin in the suppression of the morphine-induced rewarding effect under a neuropathic pain-like state","volume":"435","author":"Niikura","year":"2008","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0225","doi-asserted-by":"crossref","first-page":"3251","DOI":"10.1523\/JNEUROSCI.5173-03.2004","article-title":"A transgenic marker for newly born granule cells in dentate gyrus","volume":"24","author":"Overstreet","year":"2004","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0230","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1002\/(SICI)1096-9861(19961021)374:3<387::AID-CNE6>3.0.CO;2-Y","article-title":"Organization of projections from the basomedial nucleus of the amygdala: a PHAL study in the rat","volume":"374","author":"Petrovich","year":"1996","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0235","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00213-011-2464-4","article-title":"Dose escalation and dose preference in extended-access heroin self-administration in Lewis and Fischer rats","volume":"220","author":"Picetti","year":"2012","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0240","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1126\/science.1089459","article-title":"Rapid rewiring of arcuate nucleus feeding circuits by leptin","volume":"304","author":"Pinto","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0245","doi-asserted-by":"crossref","first-page":"4826","DOI":"10.1128\/MCB.20.13.4826-4837.2000","article-title":"Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family","volume":"20","author":"Poulin","year":"2000","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0250","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.pbb.2005.08.019","article-title":"Reconditioning of heroin place preference requires the basolateral amygdala","volume":"82","author":"Rizos","year":"2005","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0255","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0092-8674(00)81247-7","article-title":"Emotion: systems, cells, synaptic plasticity","volume":"85","author":"Rogan","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0260","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1038\/npp.2009.56","article-title":"Distinct profiles of anxiety and dysphoria during spontaneous withdrawal from acute morphine exposure","volume":"34","author":"Rothwell","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0265","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.pbb.2011.07.013","article-title":"Regional mRNA expression of the endogenous opioid and dopaminergic systems in brains of C57BL\/6J and 129P3\/J mice. strain and heroin effects","volume":"100","author":"Schlussman","year":"2011","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0270","doi-asserted-by":"crossref","first-page":"3714","DOI":"10.1523\/JNEUROSCI.20-10-03714.2000","article-title":"Neuronal basic helix-loop-helix proteins (NEX and BETA2\/Neuro D) regulate terminal granule cell differentiation in the hippocampus","volume":"20","author":"Schwab","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0275","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0165-0173(93)90007-M","article-title":"Sexual dimorphism in the vomeronasal pathway and sex differences in reproductive behaviors","volume":"18","author":"Segovia","year":"1993","journal-title":"Brain Res Rev"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0280","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s00213-011-2380-7","article-title":"Measuring the incentive value of escalating doses of heroin in heroin-dependent Fischer rats during acute spontaneous withdrawal","volume":"219","author":"Seip","year":"2012","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0285","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/s002130100748","article-title":"Time-dependent changes in extinction behavior and stress-induced reinstatement of drug seeking following withdrawal from heroin in rats","volume":"156","author":"Shalev","year":"2001","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0290","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/BF02244761","article-title":"Endogenous kappa-opioid systems in opiate withdrawal: role in aversion and accompanying changes in mesolimbic dopamine release","volume":"115","author":"Spanagel","year":"1994","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0295","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/6368","article-title":"Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus","volume":"2","author":"van Praag","year":"1999","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0300","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1097\/00001756-200408260-00004","article-title":"The amygdala is critical for opioid-mediated binge eating of fat","volume":"15","author":"Will","year":"2004","journal-title":"Neuroreport"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0305","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1111\/j.1749-6632.1998.tb10594.x","article-title":"Integration of chemosensory and hormonal input in the male Syrian hamster brain","volume":"855","author":"Wood","year":"1998","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0310","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/sj.npp.1301419","article-title":"Involvement of arginine vasopressin and V1b receptor in heroin withdrawal and heroin seeking precipitated by stress and by heroin","volume":"33","author":"Zhou","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2012.12.071_b0315","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/0196-9781(96)00014-9","article-title":"Modulation of CRF-R1 mRNA in rat anterior pituitary by dexamethasone: correlation with POMC mRNA","volume":"17","author":"Zhou","year":"1996","journal-title":"Peptides"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452213000341?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452213000341?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,2,6]],"date-time":"2022-02-06T07:58:16Z","timestamp":1644134296000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452213000341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":63,"alternative-id":["S0306452213000341"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2012.12.071","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2013,4]]}}}