{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T20:18:46Z","timestamp":1787084326596,"version":"build-2736575974"},"reference-count":108,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.neuroscience.2013.02.014","type":"journal-article","created":{"date-parts":[[2013,2,18]],"date-time":"2013-02-18T23:40:05Z","timestamp":1361230805000},"page":"168-184","source":"Crossref","is-referenced-by-count":47,"special_numbering":"C","title":["Perineuronal and perisynaptic extracellular matrix in the human spinal cord"],"prefix":"10.1016","volume":"238","author":[{"given":"C.","family":"J\u00e4ger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Lendvai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Seeger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Br\u00fcckner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.T.","family":"Matthews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Arendt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Alp\u00e1r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Morawski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2013.02.014_b0005","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0306-4522(01)00419-5","article-title":"Perineuronal nets in the rhesus monkey and human basal forebrain including basal ganglia","volume":"108","author":"Adams","year":"2001","journal-title":"Neuroscience"},{"issue":"7355","key":"10.1016\/j.neuroscience.2013.02.014_b0010","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/nature10199","article-title":"Functional regeneration of respiratory pathways after spinal cord injury","volume":"475","author":"Alilain","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0015","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.expneurol.2011.09.008","article-title":"Alterations in chondroitin sulfate proteoglycan expression occur both at and far from the site of spinal contusion injury","volume":"235","author":"Andrews","year":"2012","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0020","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3389\/neuro.02.025.2009","article-title":"Localization of glycine receptors in the human forebrain, brainstem, and cervical spinal cord: an immunohistochemical review","volume":"2","author":"Baer","year":"2009","journal-title":"Front Mol Neurosci"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0025","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1152\/physrev.2000.80.4.1267","article-title":"Proteoglycans in the developing brain: new conceptual insights for old proteins","volume":"80","author":"Bandtlow","year":"2000","journal-title":"Physiol Rev"},{"issue":"42","key":"10.1016\/j.neuroscience.2013.02.014_b0030","doi-asserted-by":"crossref","first-page":"10856","DOI":"10.1523\/JNEUROSCI.2980-06.2006","article-title":"Chondroitinase ABC promotes sprouting of intact and injured spinal systems after spinal cord injury","volume":"26","author":"Barritt","year":"2006","journal-title":"J Neurosci"},{"issue":"1","key":"10.1016\/j.neuroscience.2013.02.014_b0035","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.expneurol.2011.08.008","article-title":"Chondroitin sulphate proteoglycans: key modulators of spinal cord and brain plasticity","volume":"235","author":"Bartus","year":"2011","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0040","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/S1044-7431(03)00133-7","article-title":"Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets","volume":"24","author":"Bekku","year":"2003","journal-title":"Mol Cell Neurosci"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0045","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1679\/aohc.73.95","article-title":"Neurocan contributes to the molecular heterogeneity of the perinodal ECM","volume":"73","author":"Bekku","year":"2010","journal-title":"Arch Histol Cytol"},{"issue":"2","key":"10.1016\/j.neuroscience.2013.02.014_b0050","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s004410050538","article-title":"Immunohistochemical mapping of perineuronal nets containing chondroitin unsulfated proteoglycan in the rat central nervous system","volume":"283","author":"Bertolotto","year":"1996","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0055","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0166-2236(03)00168-1","article-title":"Molecular basis of plasticity in the visual cortex","volume":"26","author":"Berardi","year":"2003","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0060","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.neuroscience.2012.10.003","article-title":"Unique features of extracellular matrix in the mouse medial nucleus of trapezoid body \u2013 implications for physiological functions","volume":"228","author":"Blosa","year":"2013","journal-title":"Neuroscience"},{"issue":"6881","key":"10.1016\/j.neuroscience.2013.02.014_b0065","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1038\/416636a","article-title":"Chondroitinase ABC promotes functional recovery after spinal cord injury","volume":"416","author":"Bradbury","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0515","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0006-8993(93)91205-7","article-title":"Distribution of parvalbumin-containing neurons and lectin-binding perineuronal nets in the rat basal forebrain","volume":"631","author":"Brauer","year":"1993","journal-title":"Brain Res."},{"issue":"4\u20135","key":"10.1016\/j.neuroscience.2013.02.014_b0570","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.brainresbull.2010.06.015","article-title":"Manipulating the glial scar: chondroitinase ABC as a therapy for spinal cord injury","volume":"84","author":"Bradbury","year":"2011","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0075","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/glia.440080306","article-title":"Perineuronal nets provide a polyanionic, glia-associated form of microenvironment around certain neurons in many parts of the rat brain","volume":"8","author":"Br\u00fcckner","year":"1993","journal-title":"Glia"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0520","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0006-8993(09)90012-9","article-title":"Cortical areas are revealed by distribution patterns of proteoglycan components and parvalbumin in the Mongolian gerbil and rat","volume":"658","author":"Br\u00fcckner","year":"1994","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0525","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/BF02284806","article-title":"Extracellular matrix organization in various regions of rat brain grey matter","volume":"25","author":"Br\u00fcckner","year":"1996","journal-title":"J Neurocytol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0080","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s004290050135","article-title":"Cortical perineuronal nets in the gray short-tailed opossum (Monodelphis domestica): a distribution pattern contrasting with that shown in placental mammals","volume":"197","author":"Br\u00fcckner","year":"1998","journal-title":"Anat Embryol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0085","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1007\/s002210050463","article-title":"Acute and long-lasting changes in extracellular-matrix chondroitin-sulfate proteoglycans induced by injection of chondroitinase ABC in the adult rat brain","volume":"121","author":"Br\u00fcckner","year":"1998","journal-title":"Exp Brain Res"},{"issue":"3","key":"10.1016\/j.neuroscience.2013.02.014_b0090","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/S0306-4522(99)00071-8","article-title":"Cortical areas abundant in extracellular matrix chondroitin sulphate proteoglycans are less affected by cytoskeletal changes in Alzheimer\u2019s disease","volume":"92","author":"Br\u00fcckner","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0095","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1002\/1096-9861(20001225)428:4<616::AID-CNE3>3.0.CO;2-K","article-title":"Postnatal development of perineuronal nets in wild-type mice and in a mutant deficient in tenascin-R","volume":"428","author":"Br\u00fcckner","year":"2000","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0530","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0891-0618(03)00036-X","article-title":"Region and lamina-specific distribution of extracellular matrix proteoglycans, hyaluronan and tenascin-R in the mouse hippocampal formation","volume":"26","author":"Br\u00fcckner","year":"2003","journal-title":"J Chem Neuroanat"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0100","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.neuroscience.2005.11.068","article-title":"Axon initial segment ensheathed by extracellular matrix in perineuronal nets","volume":"138","author":"Br\u00fcckner","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0105","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.neuroscience.2007.10.033","article-title":"Aggrecan-based extracellular matrix is an integral part of the human basal ganglia circuit","volume":"151","author":"Br\u00fcckner","year":"2008","journal-title":"Neuroscience"},{"issue":"1","key":"10.1016\/j.neuroscience.2013.02.014_b0110","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.conb.2006.09.004","article-title":"The role of extracellular matrix in CNS regeneration","volume":"17","author":"Busch","year":"2007","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0115","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1002\/cne.20822","article-title":"Composition of perineuronal nets in the adult rat cerebellum and the cellular origin of their components","volume":"494","author":"Carulli","year":"2006","journal-title":"J Comp Neurol"},{"issue":"1","key":"10.1016\/j.neuroscience.2013.02.014_b0120","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/cne.21231","article-title":"Upregulation of aggrecan, link protein 1, and hyaluronan synthases during formation of perineuronal nets in the rat cerebellum","volume":"501","author":"Carulli","year":"2007","journal-title":"J Comp Neurol"},{"issue":"8","key":"10.1016\/j.neuroscience.2013.02.014_b0125","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1093\/brain\/awq145","article-title":"Animals lacking link protein have attenuated perineuronal nets and persistent plasticity","volume":"133","author":"Carulli","year":"2010","journal-title":"Brain"},{"issue":"1","key":"10.1016\/j.neuroscience.2013.02.014_b0130","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/0165-0173(94)90006-X","article-title":"Perineuronal nets \u2013 a specialized form of extracellular matrix in the adult nervous system","volume":"19","author":"Celio","year":"1994","journal-title":"Brain Res Rev"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0135","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/293300a0","article-title":"Calcium-binding protein parvalbumin as a neuronal marker","volume":"293","author":"Celio","year":"1981","journal-title":"Nature"},{"issue":"12","key":"10.1016\/j.neuroscience.2013.02.014_b0140","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/S0166-2236(98)01298-3","article-title":"Perineuronal nets: past and present","volume":"21","author":"Celio","year":"1998","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0145","series-title":"Das Nervensystem des Menschen","author":"Clara","year":"1959"},{"issue":"2","key":"10.1016\/j.neuroscience.2013.02.014_b0150","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.expneurol.2007.05.001","article-title":"How does chondroitinase promote functional recovery in the damaged CNS?","volume":"206","author":"Crespo","year":"2007","journal-title":"Exp Neurol"},{"issue":"26","key":"10.1016\/j.neuroscience.2013.02.014_b0155","doi-asserted-by":"crossref","first-page":"17789","DOI":"10.1074\/jbc.M600544200","article-title":"Composition of perineuronal net extracellular matrix in rat brain: a different disaccharide composition for the net-associated proteoglycans","volume":"281","author":"Deepa","year":"2006","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0160","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.neuroscience.2006.07.054","article-title":"Monoclonal antibody Cat-315 detects a glycoform of receptor protein tyrosine phosphatase beta\/phosphacan early in CNS development that localizes to extrasynaptic sites prior to synapse formation","volume":"142","author":"Dino","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0165","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/nrn1115","article-title":"Extracellular matrix molecules and synaptic plasticity","volume":"4","author":"Dityatev","year":"2003","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0170","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.tins.2010.08.003","article-title":"Compartmentalization from the outside: the extracellular matrix and functional microdomains in the brain","volume":"33","author":"Dityatev","year":"2010","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0175","first-page":"772","article-title":"Nuove osservazioni sulla struttura della cellula nervosa","volume":"24","author":"Donaggio","year":"1898","journal-title":"Riv Sper Freniatr"},{"issue":"6","key":"10.1016\/j.neuroscience.2013.02.014_b0180","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1093\/brain\/awp121","article-title":"Recovery from spinal cord injury: regeneration, plasticity and rehabilitation","volume":"132","author":"Fawcett","year":"2009","journal-title":"Brain"},{"issue":"7","key":"10.1016\/j.neuroscience.2013.02.014_b0185","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1038\/nm0709-735","article-title":"Damage control in the nervous system: rehabilitation in a plastic environment","volume":"15","author":"Fawcett","year":"2009","journal-title":"Nat Med"},{"issue":"2","key":"10.1016\/j.neuroscience.2013.02.014_b0190","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.expneurol.2007.05.014","article-title":"CNS injury, glial scars, and inflammation: inhibitory extracellular matrices and regeneration failure","volume":"209","author":"Fitch","year":"2008","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0535","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1002\/(SICI)1098-1063(1996)6:4<347::AID-HIPO1>3.0.CO;2-I","article-title":"Interneurons of the hippocampus","volume":"6","author":"Freund","year":"1996","journal-title":"Hippocampus"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0195","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1038\/nn.2338","article-title":"Brain extracellular matrix affects AMPA receptor lateral mobility and short-term synaptic plasticity","volume":"12","author":"Frischknecht","year":"2009","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainresrev.2006.09.006","article-title":"The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system","volume":"54","author":"Galtrey","year":"2007","journal-title":"Brain Res Rev"},{"issue":"6","key":"10.1016\/j.neuroscience.2013.02.014_b0210","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1111\/j.1460-9568.2008.06108.x","article-title":"Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin-R in the rat spinal cord","volume":"27","author":"Galtrey","year":"2008","journal-title":"Eur J Neurosci"},{"issue":"9","key":"10.1016\/j.neuroscience.2013.02.014_b0215","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1038\/nn.2377","article-title":"Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation","volume":"12","author":"Garc\u00eda-Al\u00edas","year":"2009","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0540","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.expneurol.2011.09.009","article-title":"Training and anti-CSPG combination therapy for spinal cord injury","volume":"235","author":"Garc\u00eda-Al\u00edas","year":"2012","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0545","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0304-3940(87)90163-7","article-title":"Co-localization of choline acetyltransferase and postsynaptic glycine receptors in motoneurons of rat spinal cord demonstrated by immunocytochemistry","volume":"82","author":"Geyer","year":"1987","journal-title":"Neurosci Lett"},{"issue":"4","key":"10.1016\/j.neuroscience.2013.02.014_b0230","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1016\/j.neuroscience.2010.08.032","article-title":"Perineuronal net formation and structure in aggrecan knockout mice","volume":"170","author":"Giamanco","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0240","unstructured":"Golgi C (1882) Nervoso (Sistema). In: Enciclopedia medica Vallardi, Vol. 3, No. 1, pp. 93\u2013122."},{"key":"10.1016\/j.neuroscience.2013.02.014_b0245","first-page":"379","article-title":"Intorno all\u2019origine del quarto nervo cerebrale e una questione isto-fisiologica che a questo argomento si collega","volume":"2","author":"Golgi","year":"1893","journal-title":"Rendiconti della Reale Accademia dei Lincei"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0250","first-page":"1","article-title":"Intorno alla struttura delle celle nervose","volume":"1","author":"Golgi","year":"1898","journal-title":"Boll Soc Med Chir Pavia"},{"issue":"10","key":"10.1016\/j.neuroscience.2013.02.014_b0255","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1097\/00001756-199210000-00012","article-title":"Wisteria floribunda agglutinin-labelled nets surround parvalbumin-containing neurons","volume":"3","author":"H\u00e4rtig","year":"1992","journal-title":"Neuroreport"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0260","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0006-8993(95)01016-O","article-title":"Allocation of perineuronal nets and parvalbumin-, calbindin-D28- and glutamic acid decarboxylase-immunoreactivity in the amygdala of the rhesus monkey","volume":"698","author":"H\u00e4rtig","year":"1995","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0265","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0006-8993(99)01784-9","article-title":"Cortical neurons immunoreactive for the potassium channel Kv3.1b subunit are predominantly surrounded by perineuronal nets presumed as a buffering system for cations","volume":"842","author":"H\u00e4rtig","year":"1999","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0270","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1111\/j.1471-4159.2006.04144.x","article-title":"Synaptic and vesicular co-localization of the glutamate transporters VGLUT1 and VGLUT2 in the mouse hippocampus","volume":"99","author":"Herzog","year":"2006","journal-title":"J Neurochem"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0275","doi-asserted-by":"crossref","first-page":"5758","DOI":"10.1073\/pnas.80.18.5758","article-title":"A surface antigen expressed by a subset of neurons in the vertebrate central nervous system","volume":"80","author":"Hockfield","year":"1983","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0280","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1101\/SQB.1990.055.01.049","article-title":"Expression of neural proteoglycans correlates with the acquisition of mature neuronal properties in the mammalian brain.-","volume":"55","author":"Hockfield","year":"1990","journal-title":"Cold Spring Harb Symp Quant Biol"},{"issue":"30","key":"10.1016\/j.neuroscience.2013.02.014_b0285","doi-asserted-by":"crossref","first-page":"7761","DOI":"10.1523\/JNEUROSCI.4659-09.2010","article-title":"Role of chondroitin sulfate proteoglycans in axonal conduction in mammalian spinal cord","volume":"9","author":"Hunanyan","year":"2010","journal-title":"J Neurosci"},{"issue":"7","key":"10.1016\/j.neuroscience.2013.02.014_b0290","doi-asserted-by":"crossref","first-page":"2350","DOI":"10.1523\/JNEUROSCI.08-07-02350.1988","article-title":"Molecular evidence for early activity-dependent development of hamster motor neurons","volume":"8","author":"Kalb","year":"1988","journal-title":"J Neurosci"},{"issue":"22","key":"10.1016\/j.neuroscience.2013.02.014_b0295","doi-asserted-by":"crossref","first-page":"20026","DOI":"10.1074\/jbc.M109218200","article-title":"Macrophage\/microglia-specific protein Iba1 enhances membrane ruffling and Rac activation via phospholipase C-gamma-dependent pathway","volume":"277","author":"Kanazawa","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0300","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/0006-8993(89)90416-2","article-title":"Vicia villosa lectin-positive neurones in human cerebral cortex. Loss in Alzheimer-type dementia","volume":"498","author":"Kobayashi","year":"1989","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0305","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s004410050790","article-title":"Developmental patterns of proteoglycan-containing extracellular matrix in perineuronal nets and neuropil of the postnatal rat brain","volume":"288","author":"K\u00f6ppe","year":"1997","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0550","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1111\/j.1460-9568.2009.06773.x","article-title":"Nonselective innervation of lamina I projection neurons by cocaine- and amphetamine-regulated transcript peptide (CART)-immunoreactive fibres in the rat spinal dorsal horn","volume":"29","author":"Kozsurek","year":"2009","journal-title":"Eur J Neurosci"},{"issue":"5","key":"10.1016\/j.neuroscience.2013.02.014_b0310","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1111\/j.1471-4159.2010.06878.x","article-title":"In vitro modeling of perineuronal nets: hyaluronan synthase and link protein are necessary for their formation and integrity","volume":"114","author":"Kwok","year":"2010","journal-title":"J Neurochem"},{"issue":"11","key":"10.1016\/j.neuroscience.2013.02.014_b0315","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1002\/dneu.20974","article-title":"Extracellular matrix and perineuronal nets in CNS repair","volume":"71","author":"Kwok","year":"2011","journal-title":"Dev Neurobiol"},{"issue":"2","key":"10.1016\/j.neuroscience.2013.02.014_b0320","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1002\/jnr.22761","article-title":"Perisynaptic aggrecan-based extracellular matrix coats in the human lateral geniculate body devoid of perineuronal nets","volume":"90","author":"Lendvai","year":"2012","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0325","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00401-012-1042-0","article-title":"Neurochemical mapping of the human hippocampus reveals perisynaptic matrix around functional synapses in Alzheimer\u2019s disease","volume":"125","author":"Lendvai","year":"2013","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0330","first-page":"5","article-title":"Sulla struttura del nucleo dentato del cervelletto nell\u2019uomo","volume":"6","author":"Lugaro","year":"1895","journal-title":"Monit Zool Ital"},{"issue":"6","key":"10.1016\/j.neuroscience.2013.02.014_b0335","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1002\/hipo.20780","article-title":"Kalirin-7, an important component of excitatory synapses, is regulated by estradiol in hippocampal neurons","volume":"21","author":"Ma","year":"2011","journal-title":"Hippocampus"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0555","doi-asserted-by":"crossref","first-page":"4406","DOI":"10.1523\/JNEUROSCI.5467-05.2006","article-title":"Chondroitinase ABC digestion of the perineuronal net promotes functional collateral sprouting in the cuneate nucleus after cervical spinal cord injury","volume":"26","author":"Massey","year":"2006","journal-title":"J Neurosci"},{"issue":"30","key":"10.1016\/j.neuroscience.2013.02.014_b0345","doi-asserted-by":"crossref","first-page":"22695","DOI":"10.1074\/jbc.M909764199","article-title":"Brain-enriched hyaluronan binding (BEHAB)\/brevican cleavage in a glioma cell line is mediated by a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family member","volume":"275","author":"Matthews","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0350","doi-asserted-by":"crossref","first-page":"7536","DOI":"10.1523\/JNEUROSCI.22-17-07536.2002","article-title":"Aggrecan glycoforms contribute to the molecular heterogeneity of perineuronal nets","volume":"22","author":"Matthews","year":"2002","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0355","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.expneurol.2004.04.017","article-title":"Perineuronal nets potentially protect against oxidative stress","volume":"188","author":"Morawski","year":"2004","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0360","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.brainres.2009.02.046","article-title":"Chondroitin sulfate proteoglycan-based extracellular matrix in chicken (Gallus domesticus) brain","volume":"1275","author":"Morawski","year":"2009","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0365","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1016\/j.neurobiolaging.2008.07.023","article-title":"Perineuronal nets are largely unaffected in Alzheimer model Tg2576 mice","volume":"31","author":"Morawski","year":"2010","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0370","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.neuroscience.2009.08.018","article-title":"Aggrecan-based extracellular matrix shows unique cortical features and conserved subcortical principles of mammalian brain organization in the Madagascan lesser hedgehog tenrec (Echinops telfairi Martin, 1838)","volume":"165","author":"Morawski","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0375","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/j.neuroscience.2010.05.022","article-title":"Neurons associated with aggrecan-based perineuronal nets are protected against tau pathology in subcortical regions in Alzheimer\u2019s disease","volume":"169","author":"Morawski","year":"2010","journal-title":"Neuroscience"},{"issue":"5","key":"10.1016\/j.neuroscience.2013.02.014_b0380","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.biocel.2012.01.010","article-title":"Aggrecan: beyond cartilage and into the brain","volume":"44","author":"Morawski","year":"2012","journal-title":"Int J Biochem Cell Biol"},{"issue":"4","key":"10.1016\/j.neuroscience.2013.02.014_b0385","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1111\/j.1750-3639.2011.00557.x","article-title":"Involvement of perineuronal and perisynaptic extracellular matrix in Alzheimer\u2019s disease neuropathology","volume":"22","author":"Morawski","year":"2012","journal-title":"Brain Pathol"},{"issue":"3","key":"10.1016\/j.neuroscience.2013.02.014_b0390","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1679\/aohc.62.273","article-title":"The extracellular matrix in the mouse brain: its reactions to endo-alpha-N-acetylgalactosaminidase and certain other enzymes","volume":"62","author":"Murakami","year":"1999","journal-title":"Arch Histol Cytol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0560","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/BF01923584","article-title":"The link proteins","volume":"49","author":"Neame","year":"1993","journal-title":"Experientia"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0395","first-page":"53","article-title":"The link proteins","volume":"70","author":"Neame","year":"1994","journal-title":"Experientia"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0400","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/(SICI)1096-9861(19971222)389:3<453::AID-CNE7>3.0.CO;2-#","article-title":"Labeling of pyramidal and nonpyramidal neurons with lectin Vicia villosa during postnatal development of the guinea pig","volume":"389","author":"Ohyama","year":"1997","journal-title":"J Comp Neurol"},{"issue":"2","key":"10.1016\/j.neuroscience.2013.02.014_b0405","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.expneurol.2006.12.012","article-title":"Matrix metalloproteinases and proteoglycans in axonal regeneration","volume":"204","author":"Pizzi","year":"2007","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0410","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1126\/science.1072699","article-title":"Reactivation of ocular dominance plasticity in the adult visual cortex","volume":"298","author":"Pizzorusso","year":"2002","journal-title":"Science"},{"issue":"22","key":"10.1016\/j.neuroscience.2013.02.014_b0415","doi-asserted-by":"crossref","first-page":"8517","DOI":"10.1073\/pnas.0602657103","article-title":"Structural and functional recovery from early monocular deprivation in adult rats","volume":"103","author":"Pizzorusso","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0420","first-page":"105","article-title":"Las c\u00e9lulas de cilindro-eje corto de la capa molecular del cerebro","volume":"2","author":"Ram\u00f3n y Cajal","year":"1897","journal-title":"Rev Trim Microgr"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0425","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1042\/BST0350656","article-title":"Brain matrix: structure, turnover and necessity","volume":"35","author":"Rauch","year":"2007","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0430","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S0168-583X(03)01041-3","article-title":"Quantitative microanalysis of perineuronal nets in brain tissue","volume":"210","author":"Reinert","year":"2003","journal-title":"Nucl Instrum Meth B"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0435","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1469-7580.2004.00261.x","article-title":"Chondroitin sulphate proteoglycans: preventing plasticity or protecting the CNS?","volume":"204","author":"Rhodes","year":"2004","journal-title":"J Anat"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0440","unstructured":"Romeis \u2013 Mikroskopische Technik (2010) Mulisch, Maria; Welsch, Ulrich (Hrsg.) 18. Aufl., XII, 556."},{"issue":"6","key":"10.1016\/j.neuroscience.2013.02.014_b0445","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1177\/002215549904700601","article-title":"Reduction of lipofuscin-like autofluorescence in fluorescently labeled tissue","volume":"47","author":"Schnell","year":"1999","journal-title":"J Histochem Cytochem"},{"issue":"2","key":"10.1016\/j.neuroscience.2013.02.014_b0450","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0306-4522(94)90044-2","article-title":"Mapping of perineuronal nets in the rat brain stained by colloidal iron hydroxide histochemistry and lectin cytochemistry","volume":"58","author":"Seeger","year":"1994","journal-title":"Neuroscience"},{"issue":"3","key":"10.1016\/j.neuroscience.2013.02.014_b0455","first-page":"351","article-title":"Distribution patterns of Wisteria floribunda agglutinin binding sites and parvalbumin-immunoreactive neurons in the human visual cortex: a double-labelling study","volume":"37","author":"Seeger","year":"1996","journal-title":"J Hirnforsch"},{"issue":"23","key":"10.1016\/j.neuroscience.2013.02.014_b0460","doi-asserted-by":"crossref","first-page":"21083","DOI":"10.1074\/jbc.M213100200","article-title":"A hyaluronan binding link protein gene family whose members are physically linked adjacent to chondroitin sulfate proteoglycan core protein genes: the missing links","volume":"278","author":"Spicer","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0465","series-title":"Gray\u2019s Anatomy: The Anatomical Basis of Clinical Practice","year":"2008"},{"issue":"6","key":"10.1016\/j.neuroscience.2013.02.014_b0470","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1002\/cne.20960","article-title":"Distribution of hyaluronan in the central nervous system of the frog","volume":"496","author":"Szigeti","year":"2006","journal-title":"J Comp Neurol"},{"issue":"11","key":"10.1016\/j.neuroscience.2013.02.014_b0475","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1023\/A:1006955414939","article-title":"Three-dimensional microanatomy of perineuronal proteoglycan nets enveloping motor neurons in the rat spinal cord","volume":"27","author":"Takahashi-Iwanaga","year":"1998","journal-title":"J Neurocytol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0480","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/35025070","article-title":"Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons","volume":"407","author":"Takamori","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0565","doi-asserted-by":"crossref","first-page":"4103","DOI":"10.1523\/JNEUROSCI.22-10-04103.2002","article-title":"Projection neurons in lamina I of rat spinal cord with the neurokinin 1 receptor are selectively innervated by substance p-containing afferents and respond to noxious stimulation","volume":"22","author":"Todd","year":"2002","journal-title":"J Neurosci"},{"issue":"Suppl. 3","key":"10.1016\/j.neuroscience.2013.02.014_b0485","doi-asserted-by":"crossref","first-page":"S89","DOI":"10.33549\/physiolres.931603","article-title":"Extracellular space diffusion and extrasynaptic transmission","volume":"57","author":"Vargov\u00e1","year":"2008","journal-title":"Physiol Res"},{"issue":"10","key":"10.1016\/j.neuroscience.2013.02.014_b0490","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.molmed.2006.08.007","article-title":"From barriers to bridges: chondroitin sulfate proteoglycans in neuropathology","volume":"12","author":"Viapiano","year":"2006","journal-title":"Trends Mol Med"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0495","doi-asserted-by":"crossref","first-page":"3151","DOI":"10.1111\/j.1582-4934.2009.00694.x","article-title":"Differential distribution of aggrecan isoforms in perineuronal nets of the human cerebral cortex","volume":"13","author":"Virgintino","year":"2009","journal-title":"J Cell Mol Med"},{"issue":"3","key":"10.1016\/j.neuroscience.2013.02.014_b0500","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s00441-006-0289-y","article-title":"Differential expression of several molecules of the extracellular matrix in functionally and developmentally distinct regions of rat spinal cord","volume":"327","author":"Vitellaro-Zuccarello","year":"2007","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0505","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.matbio.2004.11.007","article-title":"Versican protects cells from oxidative stress-induced apoptosis","volume":"24","author":"Wu","year":"2005","journal-title":"Matrix Biol"},{"key":"10.1016\/j.neuroscience.2013.02.014_b0510","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1007\/PL00000690","article-title":"Lecticans: organizers of the brain extracellular matrix","volume":"57","author":"Yamaguchi","year":"2000","journal-title":"Cell Mol Life Sci"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452213001413?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452213001413?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T01:29:18Z","timestamp":1714958958000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452213001413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":108,"alternative-id":["S0306452213001413"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2013.02.014","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]}}}