{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:53:27Z","timestamp":1760298807067,"version":"3.40.5"},"reference-count":79,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1016\/j.neuroscience.2013.09.058","type":"journal-article","created":{"date-parts":[[2013,10,10]],"date-time":"2013-10-10T20:13:22Z","timestamp":1381436002000},"page":"158-176","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Methylxanthines do not affect rhythmogenic preB\u00f6tC inspiratory network activity but impair bursting of preB\u00f6tC-driven motoneurons"],"prefix":"10.1016","volume":"255","author":[{"given":"B.","family":"Panaitescu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Kuribayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9606-8557","authenticated-orcid":false,"given":"A.","family":"Ruangkittisakul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Leung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Iizuka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Ballanyi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2013.09.058_b0005","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0306-3623(98)00201-8","article-title":"Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice","volume":"32","author":"Amabeoku","year":"1999","journal-title":"Gen Pharmacol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0010","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1177\/0310057X9902700316","article-title":"Caffeine overdose in a premature infant: clinical course and pharmacokinetics","volume":"27","author":"Anderson","year":"1999","journal-title":"Anaesth Intensive Care"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0015","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0006-8993(93)91740-J","article-title":"Effects of cAMP on respiratory rhythm generation in brainstem-spinal cord preparation from newborn rat","volume":"605","author":"Arata","year":"1993","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0020","doi-asserted-by":"crossref","first-page":"221","DOI":"10.2174\/1570159043476828","article-title":"Neuromodulation of the perinatal respiratory network","volume":"2","author":"Ballanyi","year":"2004","journal-title":"Curr Neuropharmacol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0025","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.resp.2009.04.020","article-title":"Structure-function analysis of rhythmogenic inspiratory pre-B\u00f6tzinger complex networks in \u201ccalibrated\u201d newborn rat brainstem slices","volume":"168","author":"Ballanyi","year":"2009","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0030","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1469-7793.1997.127bf.x","article-title":"CAMP-dependent reversal of opioid- and prostaglandin-mediated depression of the isolated respiratory network in newborn rats","volume":"504","author":"Ballanyi","year":"1997","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0035","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0301-0082(99)00009-X","article-title":"Respiratory network function in the isolated brainstem-spinal cord of newborn rats","volume":"59","author":"Ballanyi","year":"1999","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0040","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1164\/rccm.200210-1142PP","article-title":"Theophylline: new perspectives for an old drug","volume":"167","author":"Barnes","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0045","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/S0166-2236(00)01891-9","article-title":"Structural complexity and functional diversity of endoplasmic reticulum Ca2+ stores","volume":"24","author":"Blaustein","year":"2001","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0050","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1097\/WNP.0b013e3181b7f14d","article-title":"Respiratory physiology of seizures","volume":"26","author":"Blum","year":"2009","journal-title":"J Clin Neurophysiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0055","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/978-3-642-13443-2_9","article-title":"Methylxanthines, seizures, and excitotoxicity","volume":"200","author":"Boison","year":"2011","journal-title":"Handb Exp Pharmacol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0060","doi-asserted-by":"crossref","first-page":"7063","DOI":"10.1523\/JNEUROSCI.16-21-07063.1996","article-title":"Localization of rhythmogenic networks responsible for spontaneous bursts induced by strychnine and bicuculline in the rat isolated spinal cord","volume":"16","author":"Bracci","year":"1996","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0065","doi-asserted-by":"crossref","first-page":"3823","DOI":"10.1046\/j.1460-9568.1998.00396.x","article-title":"Synaptic inhibition in the isolated respiratory network of neonatal rats","volume":"10","author":"Brockhaus","year":"1998","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0070","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0306-4522(99)00544-8","article-title":"Anticonvulsant A1 receptor-mediated adenosine action on neuronal networks in the brainstem-spinal cord of newborn rats","volume":"96","author":"Brockhaus","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0075","first-page":"31","article-title":"Hypoglossal and phrenic nerve responses to changes in oxygen tension during picrotoxin-induced seizures in the rat","volume":"55","author":"Budzi\u0144ska","year":"2004","journal-title":"J Physiol Pharmacol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0080","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1007\/s004240000453","article-title":"Reorganisation of respiratory network activity after loss of glycinergic inhibition","volume":"441","author":"B\u00fcsselberg","year":"2001","journal-title":"Pfl\u00fcgers Arch"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0085","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1097\/FTD.0b013e3181898b6f","article-title":"Caffeine citrate treatment for extremely premature infants with apnea: population pharmacokinetics, absolute bioavailability, and implications for therapeutic drug monitoring","volume":"30","author":"Charles","year":"2008","journal-title":"Ther Drug Monit"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0090","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/nrd3955","article-title":"Adenosine receptors as drug targets \u2013 what are the challenges?","volume":"12","author":"Chen","year":"2013","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0095","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1002\/mrm.21408","article-title":"Refining the sensory and motor ratunculus of the rat upper extremity using fMRI and direct nerve stimulation","volume":"58","author":"Cho","year":"2007","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0100","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1098\/rstb.2009.0071","article-title":"A repertoire of rhythmic bursting produced by hypoglossal motoneurons in physiological and pathological conditions","volume":"364","author":"Cifra","year":"2009","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0105","doi-asserted-by":"crossref","first-page":"4063","DOI":"10.1113\/jphysiol.2009.174797","article-title":"Caffeine inhibition of ionotropic glycine receptors","volume":"587","author":"Duan","year":"2009","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0110","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3810\/psm.2010.06.1796","article-title":"Energy drinks: a review of use and safety for athletes","volume":"38","author":"Duchan","year":"2010","journal-title":"Phys Sportsmed"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0115","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1113\/jphysiol.2001.013466","article-title":"Glycinergic inhibition is essential for co-ordinating cranial and spinal respiratory motor outputs in the neonatal rat","volume":"543","author":"Dutschmann","year":"2002","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0120","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1146\/annurev-physiol-040510-130049","article-title":"Understanding the rhythm of breathing: so near, yet so far","volume":"75","author":"Feldman","year":"2013","journal-title":"Annu Rev Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0125","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0031-6997(24)01396-6","article-title":"Actions of caffeine in the brain with special reference to factors that contribute to its widespread use","volume":"51","author":"Fredholm","year":"1999","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0130","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S1569-9048(02)00041-1","article-title":"High frequency oscillations in respiratory networks: functionally significant or phenomenological?","volume":"131","author":"Funk","year":"2002","journal-title":"Respir Physiol Neurobiol"},{"year":"1935","series-title":"The anatomy of the rat","author":"Greene","key":"10.1016\/j.neuroscience.2013.09.058_b0135"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0140","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.resp.2009.02.011","article-title":"Ampakine therapy to counter fentanyl-induced respiratory depression","volume":"168","author":"Greer","year":"2009","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0145","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.resp.2010.02.005","article-title":"Retrotrapezoid nucleus and parafacial respiratory group","volume":"173","author":"Guyenet","year":"2010","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0150","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.eplepsyres.2005.03.002","article-title":"Inhibition of human TREK-1 channels by caffeine and theophylline","volume":"64","author":"Harinath","year":"2005","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0155","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1203\/00006450-200201000-00004","article-title":"Perinatal respiratory control and its modulation by adenosine and caffeine in the rat","volume":"51","author":"Herlenius","year":"2002","journal-title":"Pediatr Res"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0160","doi-asserted-by":"crossref","first-page":"14713","DOI":"10.1523\/JNEUROSCI.2660-09.2009","article-title":"Tripartite purinergic modulation of central respiratory networks during perinatal development: the influence of ATP, ectonucleotidases, and ATP metabolites","volume":"29","author":"Huxtable","year":"2009","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0165","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.yebeh.2007.01.009","article-title":"New-onset seizures in adults: possible association with consumption of popular energy drinks","volume":"10","author":"Iyadurai","year":"2007","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0170","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1113\/jphysiol.2002.023408","article-title":"Opioid-resistant respiratory pathway from the preinspiratory neurones to abdominal muscles: in vivo and in vitro study in the newborn rat","volume":"545","author":"Janczewski","year":"2002","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0175","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/00019052-199404000-00007","article-title":"Experimental neurobiology of epilepsies","volume":"7","author":"Jefferys","year":"1994","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0180","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1111\/j.1460-9568.1996.tb01539.x","article-title":"Long-term treatment with some methylxanthines decreases the susceptibility to bicuculline and pentylenetetrazol-induced seizures in mice. Relationship to c-fos expression and receptor binding","volume":"8","author":"Johansson","year":"1996","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0400","doi-asserted-by":"crossref","unstructured":"Kantor C, Panaitescu B, Kuribayashi J, Ruangkittisakul A, Lee TF, Cheung PY, MacTavish D, Jhamandas J, Ballanyi K (2012) Electrophysiological imaging of early network oscillations in brain slices from newborn rats and piglets. In: Isolated central nervous system circuits (Ballanyi K, ed), Neuromethods series, Vol. 73 (Walz W, ed), pp. 315\u2013356. Springer Science+Business Media, LLC, New York, NY.","DOI":"10.1007\/978-1-62703-020-5_11"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0190","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1113\/jphysiol.1980.sp013079","article-title":"Release of calcium ions linked to the activation of potassium conductance in a caffeine-treated sympathetic neurone","volume":"298","author":"Kuba","year":"1980","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0195","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1111\/j.1553-2712.1999.tb00435.x","article-title":"Glottal patency during experimental cortical seizures in piglets","volume":"6","author":"Leaming","year":"1999","journal-title":"Acad Emerg Med"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0200","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/00007691-199606000-00012","article-title":"Saliva as a valid alternative to serum in monitoring intravenous caffeine treatment for apnea of prematurity","volume":"18","author":"Lee","year":"1996","journal-title":"Ther Drug Monit"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0205","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1055\/s-2006-958163","article-title":"Serum caffeine concentrations in preterm neonates","volume":"24","author":"Leon","year":"2007","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0210","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/75776","article-title":"Reconfiguration of the neural network controlling multiple breathing patterns: eupnea, sighs and gasps","volume":"3","author":"Lieske","year":"2000","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0215","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/329242a0","article-title":"Membrane conductance oscillations in astrocytes induced by phorbol ester","volume":"329","author":"MacVicar","year":"1987","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0220","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1080\/1040-830491379245","article-title":"Caffeine use in sports, pharmacokinetics in man, and cellular mechanisms of action","volume":"45","author":"Magkos","year":"2005","journal-title":"Crit Rev Food Sci Nutr"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0225","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1038\/jp.2010.126","article-title":"Apnea of prematurity: pathogenesis and management strategies","volume":"31","author":"Mathew","year":"2011","journal-title":"J Perinatol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0230","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.resp.2008.07.013","article-title":"Adenosinergic modulation of respiratory activity: developmental plasticity induced by perinatal caffeine administration","volume":"164","author":"Montandon","year":"2008","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0235","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/MEJ.0b013e3282703645","article-title":"Seizures and hyponatremia after excessive intake of diet coke","volume":"15","author":"Mortelmans","year":"2008","journal-title":"Eur J Emerg Med"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0240","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1098\/rstb.2009.0074","article-title":"Pontine respiratory activity involved in inspiratory\/expiratory phase transition","volume":"364","author":"M\u00f6rschel","year":"2009","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0245","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1136\/adc.64.3.357","article-title":"Seizures presenting as apnoea","volume":"64","author":"Navelet","year":"1989","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0250","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1523\/JNEUROSCI.23-04-01478.2003","article-title":"A novel functional neuron group for respiratory rhythm generation in the ventral medulla","volume":"23","author":"Onimaru","year":"2003","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0255","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1113\/jphysiol.1996.sp021249","article-title":"Calcium-dependent responses in neurons of the isolated respiratory network of newborn rats","volume":"491","author":"Onimaru","year":"1996","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0260","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.neulet.2009.03.074","article-title":"Silencing by raised extracellular Ca2+ of pre-B\u00f6tzinger complex neurons in newborn rat brainstem slices without change of membrane potential or input resistance","volume":"456","author":"Panaitescu","year":"2009","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0265","first-page":"R934","article-title":"Respiratory responses to focal and generalized seizures in cats","volume":"260","author":"Paydarfar","year":"1991","journal-title":"Am J Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0270","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.prrv.2009.06.007","article-title":"Anti-inflammatory drug therapy in asthma","volume":"10","author":"Rottier","year":"2009","journal-title":"Paediatr Respir Rev"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0275","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.resp.2010.04.025","article-title":"Methylxanthine reversal of opioid-evoked inspiratory depression via phosphodiesterase-4 blockade","volume":"172","author":"Ruangkittisakul","year":"2010","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0280","doi-asserted-by":"crossref","first-page":"11870","DOI":"10.1523\/JNEUROSCI.3357-06.2006","article-title":"High sensitivity to neuromodulator-activated signalling pathways at physiological [K+] of confocally-imaged respiratory centre neurons in online-calibrated newborn rat brainstem slices","volume":"26","author":"Ruangkittisakul","year":"2006","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0285","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1113\/jphysiol.2007.142760","article-title":"Dependence on extracellular Ca2+\/K+ antagonism of inspiratory centre rhythms in slices and en bloc preparations of newborn rat brainstem","volume":"584","author":"Ruangkittisakul","year":"2007","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0290","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1523\/JNEUROSCI.1926-07.2008","article-title":"Generation of eupnea and sighs by a spatiochemically organized inspiratory network","volume":"28","author":"Ruangkittisakul","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0295","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/978-1-4419-5692-7_25","article-title":"Caffeine reversal of opioid-evoked and endogenous inspiratory depression in perinatal rat en bloc medullas and slices","volume":"669","author":"Ruangkittisakul","year":"2010","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0405","doi-asserted-by":"crossref","unstructured":"Ruangkittisakul A, Secchia-Ballanyi L, Panaitescu B, Bobocea N, Kuribayashi J, Iizuka M, Kantor C, Ballanyi K (2012) Anatomically \u2018calibrated\u2019 isolated respiratory networks from newborn rodents. In: Isolated central nervous system circuits (Ballanyi K, ed), Neuromethods series, Vol. 73 (Walz W, ed), pp. 61\u2013124. Springer Science+Business Media, LLC, New York, NY.","DOI":"10.1007\/978-1-62703-020-5_2"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0305","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2165\/00003495-199549010-00004","article-title":"Pharmacological rationale for the clinical use of caffeine","volume":"49","author":"Sawynok","year":"1995","journal-title":"Drugs"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0310","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1113\/jphysiol.1995.sp020621","article-title":"Adenosinergic modulation of respiratory neurones and hypoxic responses in the anaesthetized cat","volume":"483","author":"Schmidt","year":"1995","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0315","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0304-3940(92)90504-Z","article-title":"Whole-cell patch-clamp recordings from respiratory neurons in neonatal rat brainstem in vitro","volume":"134","author":"Smith","year":"1992","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0320","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1126\/science.1683005","article-title":"Pre-B\u00f6tzinger complex: a brainstem region that may generate respiratory rhythm in mammals","volume":"254","author":"Smith","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0325","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/S0022-3476(80)80652-4","article-title":"Caffeine and theophylline: serum\/CSF correlation in premature infants","volume":"96","author":"Somani","year":"1980","journal-title":"J Pediatr"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0330","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1016\/0024-3205(91)90487-V","article-title":"Drug distribution studies with microdialysis. II. Caffeine and theophylline in blood, brain and other tissues in rats","volume":"49","author":"St\u00e5hle","year":"1991","journal-title":"Life Sci"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0335","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.eplepsyres.2006.05.005","article-title":"Changes in respiratory-modulated neural activities, consistent with obstructive and central apnea, during fictive seizures in an in situ anaesthetized rat preparation","volume":"70","author":"St-John","year":"2006","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0340","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1038\/nrneurol.2009.118","article-title":"Sudden unexpected death in epilepsy: risk factors and potential pathomechanisms","volume":"5","author":"Surges","year":"2009","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0345","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1113\/jphysiol.1984.sp015370","article-title":"Respiratory rhythm generation in the in vitro brain stem-spinal cord preparation of the neonatal rat","volume":"354","author":"Suzue","year":"1984","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0350","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1113\/jphysiol.2007.143594","article-title":"Anoxic persistence of lumbar respiratory bursts and block of lumbar locomotion in newborn rat brainstem spinal cords","volume":"585","author":"Taccola","year":"2007","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0355","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.neuroscience.2012.07.030","article-title":"A1 adenosine receptor modulation of chemically and electrically evoked lumbar locomotor network activity in isolated newborn rat spinal cords","volume":"222","author":"Taccola","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0360","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1111\/j.1528-1167.2008.01781.x","article-title":"Severe postictal laryngospasm as a potential mechanism for sudden unexpected death in epilepsy: a near-miss in an EMU","volume":"49","author":"Tavee","year":"2008","journal-title":"Epilepsia"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0365","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1152\/jappl.1996.80.3.924","article-title":"Respiratory motor nerve activities during experimental seizures in cats","volume":"80","author":"Terndrup","year":"1996","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0370","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1152\/jappl.1999.86.6.2052","article-title":"Effects of experimental cortical seizures on respiratory motor nerve activities in piglets","volume":"86","author":"Terndrup","year":"1999","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0375","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/S0022-3476(79)80788-X","article-title":"Relationship of plasma and CSF concentrations of caffeine in neonates with apnea","volume":"95","author":"Turmen","year":"1979","journal-title":"J Pediatr"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0380","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1476-5381.1993.tb13591.x","article-title":"Caffeine and related compounds block inhibitory amino acid-gated Cl\u2212 currents in freshly dissociated rat hippocampal neurones","volume":"109","author":"Uneyama","year":"1993","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0385","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0014-2999(84)90678-2","article-title":"Adenosine mechanisms in the regulation of breathing in the rat","volume":"106","author":"Wessberg","year":"1984","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0390","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1152\/jappl.2000.89.5.2015","article-title":"Aminophylline modulation of the mouse respiratory network changes during postnatal maturation","volume":"89","author":"Wilken","year":"2000","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.neuroscience.2013.09.058_b0395","doi-asserted-by":"crossref","first-page":"4583","DOI":"10.1113\/jphysiol.2011.210930","article-title":"Purinergic modulation of preB\u00f6tzinger complex inspiratory rhythm in rodents: the interaction between ATP and adenosine","volume":"589","author":"Zwicker","year":"2011","journal-title":"J Physiol"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452213008373?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452213008373?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T16:28:11Z","timestamp":1746030491000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452213008373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":79,"alternative-id":["S0306452213008373"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2013.09.058","relation":{},"ISSN":["0306-4522"],"issn-type":[{"type":"print","value":"0306-4522"}],"subject":[],"published":{"date-parts":[[2013,12]]}}}