{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T07:04:49Z","timestamp":1761807889313,"version":"3.40.5"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2014,5]]},"DOI":"10.1016\/j.neuroscience.2014.02.049","type":"journal-article","created":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T01:30:49Z","timestamp":1394760649000},"page":"212-220","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Auditory-cued sensorimotor task reveals disengagement deficits in rats exposed to the autism-associated teratogen valproic acid"],"prefix":"10.1016","volume":"268","author":[{"given":"T.","family":"Chomiak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5949-5090","authenticated-orcid":false,"given":"J.","family":"Hung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Cihal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Dhaliwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.I.","family":"Baghdadwala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Dzwonek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5032-0801","authenticated-orcid":false,"given":"P.","family":"Podgorny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2014.02.049_b0005","doi-asserted-by":"crossref","first-page":"D105","DOI":"10.2741\/allen","article-title":"Attention function and dysfunction in autism","volume":"6","author":"Allen","year":"2001","journal-title":"Front Biosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0010","series-title":"Principles of neural science","first-page":"317","article-title":"The anatomical organization of the central nervous system","author":"Amaral","year":"2000"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0015","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1017\/S1461145712001216","article-title":"Impairment of cortical GABAergic synaptic transmission in an environmental rat model of autism","volume":"16","author":"Banerjee","year":"2013","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0020","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1098\/rstb.2008.0337","article-title":"Talent in autism: hyper-systemizing, hyper-attention to detail and sensory hypersensitivity","volume":"364","author":"Baron-Cohen","year":"2009","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0025","first-page":"691","article-title":"The migration of neuroblasts in the developing cerebral cortex","volume":"99","author":"Berry","year":"1965","journal-title":"J Anat"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0030","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1136\/jnnp-2012-304270","article-title":"The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs","volume":"84","author":"Bromley","year":"2013","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0035","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/cne.901660208","article-title":"Neurogenesis in the visual system of the rat. An autoradiographic investigation","volume":"166","author":"Bruckner","year":"1976","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0040","series-title":"The neurobiology of autism","first-page":"34","article-title":"The autistic mind","author":"Bryson","year":"2005"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0045","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1523\/JNEUROSCI.19-01-00495.1999","article-title":"Functionally dissociating aspects of event memory: the effects of combined perirhinal and postrhinal cortex lesions on object and place memory in the rat","volume":"19","author":"Bussey","year":"1999","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0050","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1080\/01688639308402609","article-title":"Dysfunctional attention in autistic savants","volume":"15","author":"Casey","year":"1993","journal-title":"J Clin Exp Neuropsychol"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0055","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/363345a0","article-title":"A neural basis for visual search in inferior temporal cortex","volume":"363","author":"Chelazzi","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0060","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ntt.2012.08.005","article-title":"Alterations of neocortical development and maturation in autism: Insight from valproic acid exposure and animal models of autism","volume":"36","author":"Chomiak","year":"2013","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0065","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/1471-2202-11-102","article-title":"Altering the trajectory of early postnatal cortical development can lead to structural and behavioural features of autism","volume":"11","author":"Chomiak","year":"2010","journal-title":"BMC Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0070","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1152\/jn.90392.2008","article-title":"Functional architecture and spike timing properties of corticofugal projections from rat ventral temporal cortex","volume":"100","author":"Chomiak","year":"2008","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0075","first-page":"712758","article-title":"What we have learned about autism spectrum disorder from valproic acid","volume":"2013","author":"Chomiak","year":"2013","journal-title":"Patholog Res Int"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0080","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1001\/jama.2013.2270","article-title":"Prenatal valproate exposure and risk of autism spectrum disorders and childhood autism","volume":"309","author":"Christensen","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0085","series-title":"The neurology of autism","first-page":"3","article-title":"Introduction","author":"Coleman","year":"2005"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0090","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nrn755","article-title":"Control of goal-directed and stimulus-driven attention in the brain","volume":"3","author":"Corbetta","year":"2002","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0095","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/11234","article-title":"Loss of attentional stimulus selection after extrastriate cortical lesions in macaques","volume":"2","author":"De Weerd","year":"1999","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0100","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1146\/annurev.ne.18.030195.001205","article-title":"Neural mechanisms of selective visual attention","volume":"18","author":"Desimone","year":"1995","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0105","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.brainres.2013.06.024","article-title":"Increased hippocampal cell density and enhanced spatial memory in the valproic acid rat model of autism","volume":"1526","author":"Edalatmanesh","year":"2013","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0110","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3389\/fnbeh.2013.00088","article-title":"General developmental health in the VPA-rat model of autism","volume":"7","author":"Favre","year":"2013","journal-title":"Front Behav Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0115","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0166-2236(97)01128-4","article-title":"Network memory","volume":"20","author":"Fuster","year":"1997","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0120","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.neuron.2007.05.019","article-title":"Brain states: top-down influences in sensory processing","volume":"54","author":"Gilbert","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0125","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s00221-003-1611-5","article-title":"Functional organization of lemniscal and nonlemniscal auditory thalamus","volume":"153","author":"Hu","year":"2003","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0130","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.brainres.2009.09.120","article-title":"Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders","volume":"1309","author":"Hutsler","year":"2010","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0135","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1523\/JNEUROSCI.20-07-02649.2000","article-title":"Impaired preference conditioning after anterior temporal lobe resection in humans","volume":"20","author":"Johnsrude","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0140","first-page":"217","article-title":"Autistic disturbances of affective contact","volume":"2","author":"Kanner","year":"1943","journal-title":"Nerv Child"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0145","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/S0306-4522(02)00949-1","article-title":"Auditory thalamic nuclei projections to the temporal cortex in the rat","volume":"117","author":"Kimura","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0150","doi-asserted-by":"crossref","first-page":"4593","DOI":"10.1523\/JNEUROSCI.0236-05.2005","article-title":"An event-related functional magnetic resonance imaging study of voluntary and stimulus-driven orienting of attention","volume":"25","author":"Kincade","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0155","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1038\/35087595","article-title":"Retrospective and prospective coding for predicted reward in the sensory thalamus","volume":"412","author":"Komura","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0160","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1111\/j.1469-7610.2004.00304.x","article-title":"Impaired disengagement of attention in young children with autism","volume":"45","author":"Landry","year":"2004","journal-title":"J Child Psychol Psychiatry"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0165","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1007\/s10803-008-0626-y","article-title":"The effect of stimulus salience on over-selectivity","volume":"39","author":"Leader","year":"2009","journal-title":"J Autism Dev Disord"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0170","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1038\/81841","article-title":"Learning motivational significance of visual cues for reward schedules requires rhinal cortex","volume":"3","author":"Liu","year":"2000","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0175","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1002\/dev.20386","article-title":"The ontogeny of exploratory behavior in male and female adolescent rats (Rattus norvegicus)","volume":"51","author":"Lynn","year":"2009","journal-title":"Dev Psychobiol"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0180","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1038\/sj.npp.1301453","article-title":"Abnormal fear conditioning and amygdala processing in an animal model of autism","volume":"33","author":"Markram","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0185","doi-asserted-by":"crossref","first-page":"5154","DOI":"10.1523\/JNEUROSCI.16-16-05154.1996","article-title":"Neural mechanisms of visual working memory in prefrontal cortex of the macaque","volume":"16","author":"Miller","year":"1996","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0190","series-title":"Context and learning","article-title":"The several roles of context at the time of retrieval","author":"Miller","year":"1985"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0195","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1073\/pnas.0304445101","article-title":"Distinct forms of cholinergic modulation in parallel thalamic sensory pathways","volume":"101","author":"Mooney","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0200","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1136\/jmg.37.7.489","article-title":"A clinical study of 57 children with fetal anticonvulsant syndromes","volume":"37","author":"Moore","year":"2000","journal-title":"J Med Genet"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0205","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1101\/lm.41302","article-title":"Hippocampal damage and exploratory preferences in rats: memory for objects, places, and contexts","volume":"9","author":"Mumby","year":"2002","journal-title":"Learn Mem"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0210","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1159\/000341786","article-title":"Effects of rat prenatal exposure to valproic acid on behaviour and neuro-anatomy","volume":"34","author":"Mychasiuk","year":"2012","journal-title":"Dev Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0215","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1126\/science.291.5504.661","article-title":"Backward spreading of memory-retrieval signal in the primate temporal cortex","volume":"291","author":"Naya","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0220","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1093\/scan\/nsl030","article-title":"Looking you in the mouth: abnormal gaze in autism resulting from impaired top-down modulation of visual attention","volume":"1","author":"Neumann","year":"2006","journal-title":"Soc Cogn Affect Neurosci"},{"year":"1991","series-title":"Atlas of the developing rat brain","author":"Paxinos","key":"10.1016\/j.neuroscience.2014.02.049_b0225"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0230","series-title":"Topics in integrative neuroscience: from cells to cognition","first-page":"31","article-title":"Attention as an organ system","author":"Posner","year":"2008"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0235","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/nrn1903","article-title":"Typologies of attentional networks","volume":"7","author":"Raz","year":"2006","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0240","series-title":"Associative learning and conditioning theory: human and non-human applications","article-title":"Discrimination learning process in autism spectrum disorders: a comparator theory","author":"Reed","year":"2011"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0245","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ntt.2013.01.004","article-title":"In utero exposure to valproic acid and autism \u2013 a current review of clinical and animal studies","volume":"36","author":"Roullet","year":"2013","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0250","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/sj.npp.1300518","article-title":"Behavioral alterations in rats prenatally exposed to valproic acid: animal model of autism","volume":"30","author":"Schneider","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0255","doi-asserted-by":"crossref","first-page":"e43698","DOI":"10.1371\/journal.pone.0043698","article-title":"Object\/context specific memory deficits following medial frontal cortex damage in mice","volume":"7","author":"Spanswick","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0260","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ntt.2012.12.001","article-title":"Neuronal connectivity as a convergent target of gene \u00d7 environment interactions that confer risk for Autism Spectrum Disorders","volume":"36","author":"Stamou","year":"2013","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0265","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/tera.1420350205","article-title":"Teratogenicity and developmental toxicity of valproic acid in rats","volume":"35","author":"Vorhees","year":"1987","journal-title":"Teratology"},{"key":"10.1016\/j.neuroscience.2014.02.049_b0270","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.ijdevneu.2004.05.001","article-title":"Behavioral manifestations of autism in the first year of life","volume":"23","author":"Zwaigenbaum","year":"2005","journal-title":"Int J Dev Neurosci"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452214002036?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452214002036?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T08:59:38Z","timestamp":1565254778000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452214002036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5]]},"references-count":54,"alternative-id":["S0306452214002036"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2014.02.049","relation":{},"ISSN":["0306-4522"],"issn-type":[{"type":"print","value":"0306-4522"}],"subject":[],"published":{"date-parts":[[2014,5]]}}}