{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T15:18:50Z","timestamp":1784992730547,"version":"3.55.0"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1016\/j.neuroscience.2014.04.013","type":"journal-article","created":{"date-parts":[[2014,4,18]],"date-time":"2014-04-18T10:16:14Z","timestamp":1397816174000},"page":"158-167","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Neuroglobin \u2013 A potential biological marker of retinal damage induced by LED light"],"prefix":"10.1016","volume":"270","author":[{"given":"Z.-L.","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.-C.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.-H.","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.-C.","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.-N.","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.-H.","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.-T.","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.-Y.","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2014.04.013_b0005","unstructured":"American National Standards Institute, 2007. American national standard for safe use of lasers.In: Anonymous American National Standard for Safe Use of Lasers. American National Standards Institute; Laser Institute of America, Orlando, FL."},{"key":"10.1016\/j.neuroscience.2014.04.013_b0010","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1001\/archopht.1964.00970020794009","article-title":"Retinal oxygen utilization measured by hyperbaric blackout","volume":"72","author":"Anderson","year":"1964","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0015","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.preteyeres.2011.04.002","article-title":"Light-emitting diodes (LED) for domestic lighting: any risks for the eye?","volume":"30","author":"Behar-Cohen","year":"2011","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0020","doi-asserted-by":"crossref","first-page":"20660","DOI":"10.1074\/jbc.M501338200","article-title":"Divergent distribution in vascular and avascular mammalian retinae links neuroglobin to cellular respiration","volume":"280","author":"Bentmann","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0025","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1002\/iub.405","article-title":"A role for human neuroglobin in apoptosis","volume":"62","author":"Brittain","year":"2010","journal-title":"Iubmb Life"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0030","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.3390\/ijms11062306","article-title":"An antiapoptotic neuroprotective role for neuroglobin","volume":"11","author":"Brittain","year":"2010","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0035","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/978-0-387-75434-5_13","article-title":"Regulation and role of neuroglobin and cytoglobin under hypoxia","volume":"618","author":"Burmester","year":"2007","journal-title":"Hypoxia Circ"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0040","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1038\/35035093","article-title":"A vertebrate globin expressed in the brain","volume":"407","author":"Burmester","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0045","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1167\/iovs.11-7408","article-title":"Neuroglobin protection in retinal ischemia","volume":"53","author":"Chan","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0050","first-page":"1","article-title":"Blue-light photochemical retinal hazard","volume":"138","author":"CIE","year":"2000","journal-title":"CIE"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0055","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1002\/glia.21002","article-title":"In vivo expression of neuroglobin in reactive astrocytes during neuropathology in murine models of traumatic brain injury, cerebral malaria, and autoimmune encephalitis","volume":"58","author":"Dellavalle","year":"2010","journal-title":"Glia"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0060","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/j.1751-1097.1978.tb07718.x","article-title":"Retinal sensitized photodynamic damage to liposomes","volume":"28","author":"Delmelle","year":"1978","journal-title":"Photochem Photobiol"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0065","doi-asserted-by":"crossref","first-page":"38949","DOI":"10.1074\/jbc.M106438200","article-title":"Biochemical characterization and ligand binding properties of neuroglobin, a novel member of the globin family","volume":"276","author":"Dewilde","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0070","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1002\/iub.35","article-title":"A role for neuroglobin: resetting the trigger level for apoptosis in neuronal and retinal cells","volume":"60","author":"Fago","year":"2008","journal-title":"Iubmb Life"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0075","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.gene.2007.03.022","article-title":"Anoxia or oxygen and glucose deprivation in SH-SY5Y cells: a step closer to the unraveling of neuroglobin and cytoglobin functions","volume":"398","author":"Fordel","year":"2007","journal-title":"Gene"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0080","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/75614","article-title":"Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration","volume":"25","author":"Grimm","year":"2000","journal-title":"Nat Genet"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0085","first-page":"497","article-title":"Rhodopsin-mediated blue-light damage to the rat retina: effect of photoreversal of bleaching","volume":"42","author":"Grimm","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0090","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.preteyeres.2011.11.001","article-title":"The susceptibility of the retina to photochemical damage from visible light","volume":"31","author":"Hunter","year":"2012","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0095","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1096\/fj.07-100784","article-title":"Regulation of hypoxic neuronal death signaling by neuroglobin","volume":"22","author":"Khan","year":"2008","journal-title":"FASEB J"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0100","doi-asserted-by":"crossref","first-page":"17944","DOI":"10.1073\/pnas.0607497103","article-title":"Neuroglobin-overexpressing transgenic mice are resistant to cerebral and myocardial ischemia","volume":"103","author":"Khan","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0105","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1111\/j.1460-9568.2011.07790.x","article-title":"Blue light stress in retinal neuronal (R28) cells is dependent on wavelength range and irradiance","volume":"34","author":"Knels","year":"2011","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0110","article-title":"Ligand binding and protein dynamics in neuroglobin","volume":"82","author":"Kriegl","year":"2002","journal-title":"Biophys J"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0115","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1016\/j.bbamcr.2012.09.009","article-title":"Neuroglobin involvement in respiratory chain function and retinal ganglion cell integrity","volume":"1823","author":"Lechauve","year":"2012","journal-title":"Biochim Biophys Acta Mol Cell Res"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0120","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1016\/j.bbapap.2013.04.014","article-title":"Neuroglobin involvement in visual pathways through the optic nerve","volume":"1834","author":"Lechauve","year":"2013","journal-title":"Biochim Biophys Acta Proteins Proteom"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0125","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1038\/jcbfm.2010.90","article-title":"Neuroglobin protects neurons against oxidative stress in global ischemia","volume":"30","author":"Li","year":"2010","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0130","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.brainres.2007.11.022","article-title":"Neuroglobin protects PC12 cells against oxidative stress","volume":"1190","author":"Li","year":"2008","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0135","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/jnr.21826","article-title":"Effects of neuroglobin overexpression on mitochondrial function and oxidative stress following hypoxia\/reoxygenation in cultured neurons","volume":"87","author":"Liu","year":"2009","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0140","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/35035181","article-title":"Molecular physiology \u2013 globins in the brain","volume":"407","author":"Moens","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0145","doi-asserted-by":"crossref","first-page":"3715","DOI":"10.1167\/iovs.07-1430","article-title":"Light-induced retinal changes observed with high-resolution autofluorescence imaging of the retinal pigment epithelium","volume":"49","author":"Morgan","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0150","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/0042-6989(80)90055-3","article-title":"Possible mechanisms of photoreceptor damage by light in mammalian eyes","volume":"20","author":"Noell","year":"1980","journal-title":"Vision Res"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0155","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1159\/000060814","article-title":"Evaluation of blue-light hazards from various light sources","volume":"35","author":"Okuno","year":"2002","journal-title":"Dev Ophthalmol"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0160","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.preteyeres.2009.11.004","article-title":"Retinal light damage: mechanisms and protection","volume":"29","author":"Organisciak","year":"2010","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0165","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/S0969-2126(03)00166-7","article-title":"Human brain neuroglobin structure reveals a distinct mode of controlling oxygen affinity","volume":"11","author":"Pesce","year":"2003","journal-title":"Structure"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0170","doi-asserted-by":"crossref","unstructured":"Pugh, E.N. Jr. and Lamb, T. (2000) Phototransducin in vertebrate rods and cones: Molecular mechanism of amplification, recovery and light adaptation. In: Molecular Mechanism in Visual Transduction.D.G. Stavenga, W.J. Degrip and E.N. Pugh Jr., eds. (Amsterdam, The Netherlands: Elsevier Science Publishers B.V.), pp. 183\u2013255.","DOI":"10.1016\/S1383-8121(00)80008-1"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0175","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/S0306-4522(02)00536-5","article-title":"Expression analysis of neuroglobin mRNA in rodent tissues","volume":"115","author":"Reuss","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0180","first-page":"876","article-title":"Influence of blue light on photoreceptors in a live retinal explant system","volume":"17","author":"Roehlecke","year":"2011","journal-title":"Mol Vis"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0185","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/S0891-5849(97)00395-X","article-title":"Blue light-induced singlet oxygen generation by retinal lipofuscin in non-polar media","volume":"24","author":"Rozanowska","year":"1998","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0190","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1074\/jbc.M209909200","article-title":"How does the eye breathe? Evidence for neuroglobin-mediated oxygen supply in the mammalian retina","volume":"278","author":"Schmidt","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0195","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.neulet.2004.10.071","article-title":"Divergent distribution of cytoglobin and neuroglobin in the murine eye","volume":"374","author":"Schmidt","year":"2005","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0200","first-page":"393","article-title":"Expression of neuroglobin in ocular hypertension induced acute hypoxic-ischemic retinal injury in rats","volume":"4","author":"Shi","year":"2011","journal-title":"Int J Ophthalmol"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0205","doi-asserted-by":"crossref","first-page":"15306","DOI":"10.1073\/pnas.251466698","article-title":"Neuroglobin is up-regulated by and protects neurons from hypoxic-ischemic injury","volume":"98","author":"Sun","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0210","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1002\/prot.20113","article-title":"The structure of murine neuroglobin: novel pathways for ligand migration and binding","volume":"56","author":"Vallone","year":"2004","journal-title":"Proteins"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0215","doi-asserted-by":"crossref","first-page":"36505","DOI":"10.1074\/jbc.M305519200","article-title":"Oxidized human neuroglobin acts as a heterotrimeric G alpha protein guanine nucleotide dissociation inhibitor","volume":"278","author":"Wakasugi","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0220","doi-asserted-by":"crossref","first-page":"2788","DOI":"10.1016\/j.ajpath.2011.08.015","article-title":"Neuroglobin is an endogenous neuroprotectant for retinal ganglion cells against glaucomatous damage","volume":"179","author":"Wei","year":"2011","journal-title":"Am J Pathol"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0225","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.preteyeres.2004.08.002","article-title":"Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration","volume":"24","author":"Wenzel","year":"2005","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0230","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.survophthal.2006.06.009","article-title":"Photochemical damage of the retina","volume":"51","author":"Wu","year":"2006","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0235","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0304-3940(03)00563-9","article-title":"Localization of neuroglobin protein in the mouse brain","volume":"346","author":"Wystub","year":"2003","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2014.04.013_b0240","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/eye.2010.149","article-title":"Retinal light toxicity","volume":"25","author":"Youssef","year":"2011","journal-title":"Eye (Lond)"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030645221400308X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030645221400308X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T13:25:34Z","timestamp":1565357134000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S030645221400308X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":48,"alternative-id":["S030645221400308X"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2014.04.013","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]}}}