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rodents","volume":"100","author":"Sirota","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2015.04.012_b0415","doi-asserted-by":"crossref","first-page":"3865","DOI":"10.1097\/00001756-200011270-00052","article-title":"Effect of age on burst firing characteristics of rat hippocampal pyramidal cells","volume":"11","author":"Smith","year":"2000","journal-title":"NeuroReport"},{"key":"10.1016\/j.neuroscience.2015.04.012_b0420","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/j.1471-4159.2004.02318.x","article-title":"Aging in the rat hippocampus is associated with widespread reductions in the number of glutamate decarboxylase-67 positive interneurons but not interneuron degeneration","volume":"89","author":"Stanley","year":"2004","journal-title":"J Neurochem"},{"key":"10.1016\/j.neuroscience.2015.04.012_b0425","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0079-6123(08)61248-0","article-title":"Potassium currents in 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