{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:49:02Z","timestamp":1787237342183,"version":"build-2736575974"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100010801","name":"Xunta de Galicia","doi-asserted-by":"crossref","award":["2007\/000140-0"],"award-info":[{"award-number":["2007\/000140-0"]}],"id":[{"id":"10.13039\/501100010801","id-type":"DOI","asserted-by":"crossref"}]},{"name":"FPU-MECD","award":["AP2010-2774"],"award-info":[{"award-number":["AP2010-2774"]}]},{"name":"FPU-MECD","award":["AP2010-2775"],"award-info":[{"award-number":["AP2010-2775"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.neuroscience.2015.07.081","type":"journal-article","created":{"date-parts":[[2015,8,3]],"date-time":"2015-08-03T10:02:46Z","timestamp":1438596166000},"page":"316-327","source":"Crossref","is-referenced-by-count":47,"special_numbering":"C","title":["Central fatigue induced by short-lasting finger tapping and isometric tasks: A study of silent periods evoked at spinal and supraspinal levels"],"prefix":"10.1016","volume":"305","author":[{"given":"P.","family":"Arias","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Robles-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Corral-Berganti\u00f1os","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Madrid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Espinosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Valls-Sol\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.L.","family":"Grieve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Oliviero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Cudeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2015.07.081_b0005","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1152\/physrev.00015.2007","article-title":"Skeletal muscle fatigue: cellular mechanisms","volume":"88","author":"Allen","year":"2008","journal-title":"Physiol Rev"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0010","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1016\/j.clinph.2012.04.001","article-title":"Validity of the finger tapping test in Parkinson\u2019s disease, elderly and young healthy subjects: is there a role for central fatigue?","volume":"123","author":"Arias","year":"2012","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0015","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1002\/mus.880070902","article-title":"Changes in muscle contractile properties and neural control during human muscular fatigue","volume":"7","author":"Bigland-Ritchie","year":"1984","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0020","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/BF00227794","article-title":"Postexercise depression of motor evoked potentials: a measure of central nervous system fatigue","volume":"93","author":"Brasil-Neto","year":"1993","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0025","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.1600-0404.1995.tb00151.x","article-title":"Role of intracortical mechanisms in the late part of the silent period to transcranial stimulation of the human motor cortex","volume":"92","author":"Brasil-Neto","year":"1995","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0030","doi-asserted-by":"crossref","first-page":"10224","DOI":"10.1523\/JNEUROSCI.23-32-10224.2003","article-title":"Responses of human motoneurons to corticospinal stimulation during maximal voluntary contractions and ischemia","volume":"23","author":"Butler","year":"2003","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0035","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1016\/j.clinph.2011.11.034","article-title":"Origin of the low-level EMG during the silent period following transcranial magnetic stimulation","volume":"123","author":"Butler","year":"2012","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0040","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1212\/WNL.42.10.1951","article-title":"Magnetic brain stimulation: the silent period after the motor evoked potential","volume":"42","author":"Cantello","year":"1992","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0045","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/S1388-2457(99)00314-4","article-title":"Direct demonstration of the effect of lorazepam on the excitability of the human motor cortex","volume":"111","author":"Di Lazzaro","year":"2000","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0050","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s00221-003-1408-6","article-title":"Direct demonstration of reduction of the output of the human motor cortex induced by a fatiguing muscle contraction","volume":"149","author":"Di Lazzaro","year":"2003","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0055","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1113\/jphysiol.1993.sp019928","article-title":"Behaviour of short and long latency reflexes in fatigued human muscles","volume":"471","author":"Duchateau","year":"1993","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0060","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1152\/jappl.1992.72.5.1631","article-title":"Neurobiology of muscle fatigue","volume":"72","author":"Enoka","year":"1992","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0065","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1113\/jphysiol.2007.139477","article-title":"Muscle fatigue: what, why and how it influences muscle function","volume":"586","author":"Enoka","year":"2008","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0070","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.jelekin.2010.10.006","article-title":"Unraveling the neurophysiology of muscle fatigue","volume":"21","author":"Enoka","year":"2011","journal-title":"J Electromyogr Kinesiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0075","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0168-5597(91)90011-L","article-title":"Spinal motor neuron excitability during the silent period after cortical stimulation","volume":"81","author":"Fuhr","year":"1991","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0080","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1152\/physrev.2001.81.4.1725","article-title":"Spinal and supraspinal factors in human muscle fatigue","volume":"81","author":"Gandevia","year":"2001","journal-title":"Physiol Rev"},{"issue":"Pt 2","key":"10.1016\/j.neuroscience.2015.07.081_b0085","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1113\/jphysiol.1996.sp021164","article-title":"Supraspinal factors in human muscle fatigue: evidence for suboptimal output from the motor cortex","volume":"490","author":"Gandevia","year":"1996","journal-title":"J Physiol"},{"issue":"Pt 3","key":"10.1016\/j.neuroscience.2015.07.081_b0090","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1111\/j.1469-7793.1999.00749.x","article-title":"Impaired response of human motoneurones to corticospinal stimulation after voluntary exercise","volume":"521","author":"Gandevia","year":"1999","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0095","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.neuron.2007.06.026","article-title":"Transcranial magnetic stimulation: a primer","volume":"55","author":"Hallett","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0100","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1002\/hbm.21177","article-title":"Limitation of physical performance in a muscle fatiguing handgrip exercise is mediated by thalamo-insular activity","volume":"32","author":"Hilty","year":"2011","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0105","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1113\/expphysiol.2010.056226","article-title":"Spinal opioid receptor-sensitive muscle afferents contribute to the fatigue-induced increase in intracortical inhibition in healthy humans","volume":"96","author":"Hilty","year":"2011","journal-title":"Exp Physiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0110","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1113\/jphysiol.1979.sp013038","article-title":"Recurrent inhibition and afterhyperpolarization following motoneuronal discharge in the cat","volume":"297","author":"Hultborn","year":"1979","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0115","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1113\/jphysiol.1993.sp019732","article-title":"Silent period evoked by transcranial stimulation of the human cortex and cervicomedullary junction","volume":"466","author":"Inghilleri","year":"1993","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0120","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0304-3940(98)00540-0","article-title":"A parametric analysis of the \u2019rate effect\u2019 in the sensorimotor cortex: a functional magnetic resonance imaging analysis in human subjects","volume":"252","author":"Jancke","year":"1998","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0125","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1152\/jn.01252.2007","article-title":"Spinal mechanisms contribute to differences in the time to failure of submaximal","volume":"99","author":"Klass","year":"2008","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0130","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1212\/WNL.0b013e31827f07be","article-title":"Fatigue and fatigability in neurologic illnesses: proposal for a unified taxonomy","volume":"80","author":"Kluger","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0135","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.neulet.2004.09.058","article-title":"Asymmetry of cortical activation during maximum and convenient tapping speed","volume":"373","author":"Lutz","year":"2005","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0140","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.clinph.2005.12.019","article-title":"Muscle fatigue decreases short-interval intracortical inhibition after exhaustive intermittent tasks","volume":"117","author":"Maruyama","year":"2006","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0145","doi-asserted-by":"crossref","first-page":"5601","DOI":"10.1113\/jphysiol.2009.180968","article-title":"The response to paired motor cortical stimuli is abolished at a spinal level during human muscle fatigue","volume":"587","author":"McNeil","year":"2009","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0150","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s00221-009-1886-2","article-title":"Rapid slowing of maximal finger movement rate: fatigue of central motor control?","volume":"196","author":"Rodrigues","year":"2009","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0155","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0013-4694(94)90029-9","article-title":"Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application. Report of an IFCN committee","volume":"91","author":"Rossini","year":"1994","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0160","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1001\/archneur.1990.00530060095025","article-title":"The finger-tapping test. A quantitative analysis","volume":"47","author":"Shimoyama","year":"1990","journal-title":"Arch Neurol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0165","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1152\/japplphysiol.01116.2003","article-title":"Noninvasive stimulation of the human corticospinal tract","volume":"96","author":"Taylor","year":"2004","journal-title":"J Appl Physiol (1985)"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0170","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/1097-4598(200101)24:1<18::AID-MUS2>3.0.CO;2-D","article-title":"Transcranial magnetic stimulation and human muscle fatigue","volume":"24","author":"Taylor","year":"2001","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0175","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1152\/japplphysiol.01053.2007","article-title":"A comparison of central aspects of fatigue in submaximal and maximal voluntary contractions","volume":"104","author":"Taylor","year":"2008","journal-title":"J Appl Physiol"},{"issue":"Pt 2","key":"10.1016\/j.neuroscience.2015.07.081_b0180","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1113\/jphysiol.1996.sp021163","article-title":"Changes in motor cortical excitability during human muscle fatigue","volume":"490","author":"Taylor","year":"1996","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0185","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s002210050779","article-title":"Altered responses of human elbow flexors to peripheral-nerve and cortical stimulation during a sustained maximal voluntary contraction","volume":"127","author":"Taylor","year":"1999","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0190","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1152\/jappl.2000.89.1.305","article-title":"Supraspinal fatigue during intermittent maximal voluntary contractions of the human elbow flexors","volume":"89","author":"Taylor","year":"2000","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0195","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s00221-011-2906-6","article-title":"Post-exercise depression in corticomotor excitability after dynamic movement: a general property of fatiguing and non-fatiguing exercise","volume":"216","author":"Teo","year":"2012","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0200","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/ana.410290413","article-title":"Percutaneous electrical stimulation of corticospinal pathways at the level of the pyramidal decussation in humans","volume":"29","author":"Ugawa","year":"1991","journal-title":"Ann Neurol"},{"issue":"Pt 2","key":"10.1016\/j.neuroscience.2015.07.081_b0205","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1111\/j.1469-7793.1999.0591t.x","article-title":"Differential effects on motorcortical inhibition induced by blockade of GABA uptake in humans","volume":"517","author":"Werhahn","year":"1999","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0210","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/B978-0-444-53497-2.00032-2","article-title":"Pharmaco-transcranial magnetic stimulation studies of motor excitability","volume":"116","author":"Ziemann","year":"2013","journal-title":"Handb Clin Neurol"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0215","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0304-3940(93)90464-V","article-title":"Spinal and supraspinal mechanisms contribute to the silent period in the contracting soleus muscle after transcranial magnetic stimulation of human motor cortex","volume":"156","author":"Ziemann","year":"1993","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2015.07.081_b0220","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.clinph.2007.09.126","article-title":"Clinical neurophysiology of fatigue","volume":"119","author":"Zwarts","year":"2008","journal-title":"Clin Neurophysiol"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452215007083?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452215007083?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T05:56:40Z","timestamp":1717999000000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452215007083"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":44,"alternative-id":["S0306452215007083"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2015.07.081","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]}}}