{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:28:48Z","timestamp":1792787328019,"version":"4.5.0"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100006500","name":"Cure Huntington\u2019s Disease Initiative","doi-asserted-by":"publisher","award":["A-7815"],"award-info":[{"award-number":["A-7815"]}],"id":[{"id":"10.13039\/100006500","id-type":"DOI","asserted-by":"publisher"}]},{"name":"German Research Council"},{"name":"Charit\u00e9 Research Funds"},{"name":"Leibniz Institute of Neurobiology","id":[{"id":"https:\/\/ror.org\/05q9yze82","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.neuroscience.2015.10.039","type":"journal-article","created":{"date-parts":[[2015,11,5]],"date-time":"2015-11-05T01:22:24Z","timestamp":1446686544000},"page":"519-538","source":"Crossref","is-referenced-by-count":51,"special_numbering":"C","title":["Pathological gamma oscillations, impaired dopamine release, synapse loss and reduced dynamic range of unitary glutamatergic synaptic transmission in the striatum of hypokinetic Q175 Huntington mice"],"prefix":"10.1016","volume":"311","author":[{"given":"T.","family":"Rothe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Deliano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.","family":"W\u00f3jtowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Dvorzhak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2312-911X","authenticated-orcid":false,"given":"D.","family":"Harnack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Paul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Vagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Melnick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Stark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Grantyn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2015.10.039_b0005","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/0166-2236(89)90074-X","article-title":"The functional anatomy of basal ganglia disorders","volume":"12","author":"Albin","year":"1989","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0010","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0006-8993(91)91403-N","article-title":"Immunohistochemical localization of DARPP-32 in striatal projection neurons and striatal interneurons: implications for the localization of D1-like dopamine receptors on different types of striatal neurons","volume":"568","author":"Anderson","year":"1991","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0015","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1755-5949.2010.00134.x","article-title":"Dopamine and glutamate in Huntington\u2019s disease: a balancing act","volume":"16","author":"Andre","year":"2010","journal-title":"CNS Neurosci Ther"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0020","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1002\/jnr.10272","article-title":"Striatal neurochemical changes in transgenic models of Huntington\u2019s disease","volume":"68","author":"Ariano","year":"2002","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0025","doi-asserted-by":"crossref","first-page":"14845","DOI":"10.1073\/pnas.1009874107","article-title":"Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors","volume":"107","author":"Bateup","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0030","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.parkreldis.2011.05.012","article-title":"Serotonin and dopamine striatal innervation in Parkinson\u2019s disease and Huntington\u2019s chorea","volume":"17","author":"Bedard","year":"2011","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0035","doi-asserted-by":"crossref","first-page":"6809","DOI":"10.1073\/pnas.120166397","article-title":"Severe deficiencies in dopamine signaling in presymptomatic Huntington\u2019s disease mice","volume":"97","author":"Bibb","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0040","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1212\/WNL.54.9.1753","article-title":"Decreased striatal monoaminergic terminals in Huntington disease","volume":"54","author":"Bohnen","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0045","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1002\/mds.10358","article-title":"Oscillatory nature of human basal ganglia activity: relationship to the pathophysiology of Parkinson\u2019s disease","volume":"18","author":"Brown","year":"2003","journal-title":"Mov Disord"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0050","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3389\/neuro.07.028.2009","article-title":"Dissociable effects of dopamine on neuronal firing rate and synchrony in the dorsal striatum","volume":"3","author":"Burkhardt","year":"2009","journal-title":"Front Integr Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0055","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3389\/fnsys.2011.00061","article-title":"In vivo dopamine efflux is decreased in striatum of both fragment (R6\/2) and full-length (YAC128) transgenic mouse models of Huntington\u2019s disease","volume":"5","author":"Callahan","year":"2011","journal-title":"Front Syst Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0060","first-page":"RRN1182","article-title":"Rescuing the corticostriatal synaptic disconnection in the R6\/2 mouse model of Huntington\u2019s disease: exercise, adenosine receptors and ampakines","author":"Cepeda","year":"2010","journal-title":"PLoS Curr"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0065","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1523\/JNEUROSCI.23-03-00961.2003","article-title":"Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington\u2019s disease","volume":"23","author":"Cepeda","year":"2003","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0070","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/B978-0-444-63425-2.00010-6","article-title":"The role of dopamine in Huntington\u2019s disease","volume":"211","author":"Cepeda","year":"2014","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0075","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.pneurobio.2006.11.001","article-title":"The corticostriatal pathway in Huntington\u2019s disease","volume":"81","author":"Cepeda","year":"2007","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0080","doi-asserted-by":"crossref","first-page":"6480","DOI":"10.1073\/pnas.95.11.6480","article-title":"Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene","volume":"95","author":"Cha","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0085","doi-asserted-by":"crossref","first-page":"7487","DOI":"10.1073\/pnas.1204542109","article-title":"Dysregulation of dopamine receptor D2 as a sensitive measure for Huntington disease pathology in model mice","volume":"109","author":"Crook","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0090","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1159\/000375126","article-title":"Dysfunctional dopaminergic neurones in mouse models of Huntington\u2019s disease: a role for SK3 channels","volume":"15","author":"Dallerac","year":"2015","journal-title":"Neurodegener Dis"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0095","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jchemneu.2004.02.005","article-title":"Differential loss of striatal projection systems in Huntington\u2019s disease: a quantitative immunohistochemical study","volume":"27","author":"Deng","year":"2004","journal-title":"J Chem Neuroanat"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0100","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.nbd.2013.08.009","article-title":"Loss of corticostriatal and thalamostriatal synaptic terminals precedes striatal projection neuron pathology in heterozygous Q140 Huntington\u2019s disease mice","volume":"60","author":"Deng","year":"2013","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0105","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3389\/fnsys.2014.00198","article-title":"Differential loss of thalamostriatal and corticostriatal input to striatal projection neuron types prior to overt motor symptoms in the Q140 knock-in mouse model of Huntington\u2019s disease","volume":"8","author":"Deng","year":"2014","journal-title":"Front Syst Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0110","doi-asserted-by":"crossref","first-page":"6483","DOI":"10.1523\/JNEUROSCI.0435-08.2008","article-title":"Corticostriatal and thalamostriatal synapses have distinctive properties","volume":"28","author":"Ding","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0115","unstructured":"Donaldson I, Marsden C.D., Schneider S.A., Bhatia KP (2012) Huntington\u2019s Disease. pp 733\u2013784. Oxford University Press."},{"key":"10.1016\/j.neuroscience.2015.10.039_b0120","doi-asserted-by":"crossref","first-page":"e82191","DOI":"10.1371\/journal.pone.0082191","article-title":"High frequency stimulation of the subthalamic nucleus leads to presynaptic GABA(B)-dependent depression of subthalamo-nigral afferents","volume":"8","author":"Dvorzhak","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0125","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1113\/jphysiol.2012.241018","article-title":"Tonic mGluR5\/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin","volume":"591","author":"Dvorzhak","year":"2013","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0130","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.baga.2012.04.029","article-title":"Corticostriatal dysfunction and glutamate transporter 1 (GLT1) in Huntington\u2019s disease: interactions between neurons and astrocytes","volume":"2","author":"Estrada-Sanchez","year":"2012","journal-title":"Basal Ganglia"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0135","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1093\/brain\/120.3.503","article-title":"PET study of the pre- and post-synaptic dopaminergic markers for the neurodegenerative process in Huntington\u2019s disease","volume":"120","author":"Ginovart","year":"1997","journal-title":"Brain"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0140","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0306-4522(00)00008-7","article-title":"The pattern of neurodegeneration in Huntington\u2019s disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington\u2019s disease","volume":"97","author":"Glass","year":"2000","journal-title":"Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0145","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1002\/hbm.20056","article-title":"Prediction of response speed by anticipatory high-frequency (gamma band) oscillations in the human brain","volume":"24","author":"Gonzalez Andino","year":"2005","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0150","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1113\/jphysiol.1984.sp015167","article-title":"Relation between structural and release parameters at the frog sensory-motor synapse","volume":"349","author":"Grantyn","year":"1984","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0155","doi-asserted-by":"crossref","first-page":"e50717","DOI":"10.1371\/journal.pone.0050717","article-title":"Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington\u2019s disease","volume":"7","author":"Heikkinen","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0160","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/j.neuroscience.2005.06.044","article-title":"Brain-derived neurotrophic factor modulates GABAergic synaptic transmission by enhancing presynaptic glutamic acid decarboxylase 65 levels, promoting asynchronous release and reducing the number of activated postsynaptic receptors","volume":"135","author":"Henneberger","year":"2005","journal-title":"Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0165","doi-asserted-by":"crossref","first-page":"e47026","DOI":"10.1371\/journal.pone.0047026","article-title":"Dysfunctional behavioral modulation of corticostriatal communication in the R6\/2 mouse model of Huntington\u2019s disease","volume":"7","author":"Hong","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0170","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1152\/jn.01056.2014","article-title":"Altered excitatory and inhibitory inputs to striatal medium-sized spiny neurons and cortical pyramidal neurons in the Q175 mouse model of Huntington\u2019s disease","volume":"113","author":"Indersmitten","year":"2015","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0175","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1097\/NEN.0b013e3181ee005d","article-title":"Hyperdopaminergic status in experimental Huntington disease","volume":"69","author":"Jahanshahi","year":"2010","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0180","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1111\/j.1471-4159.2006.03762.x","article-title":"Dopamine release is severely compromised in the R6\/2 mouse model of Huntington\u2019s disease","volume":"97","author":"Johnson","year":"2006","journal-title":"J Neurochem"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0185","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1523\/JNEUROSCI.5687-08.2009","article-title":"Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease","volume":"29","author":"Joshi","year":"2009","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0190","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1111\/j.1460-9568.2006.05179.x","article-title":"N-ethylmaleimide increases release probability at GABAergic synapses in layer I of the mouse visual cortex","volume":"24","author":"Kirmse","year":"2006","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0195","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0006-8993(84)91347-7","article-title":"Passive electrical membrane properties of rat neostriatal neurons in an in vitro slice preparation","volume":"300","author":"Kita","year":"1984","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0200","doi-asserted-by":"crossref","first-page":"18126","DOI":"10.1073\/pnas.1216403109","article-title":"Effects of dopamine depletion on LFP oscillations in striatum are task- and learning-dependent and selectively reversed by L-DOPA","volume":"109","author":"Lemaire","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0205","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.neuron.2011.11.015","article-title":"RGS4 is required for dopaminergic control of striatal LTD and susceptibility to parkinsonian motor deficits","volume":"73","author":"Lerner","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0210","doi-asserted-by":"crossref","first-page":"e69993","DOI":"10.1371\/journal.pone.0069993","article-title":"The Q175 mouse model of Huntington\u2019s disease shows gene dosage- and age-related decline in circadian rhythms of activity and sleep","volume":"8","author":"Loh","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0215","doi-asserted-by":"crossref","first-page":"2382","DOI":"10.1016\/j.neurobiolaging.2014.04.024","article-title":"Age-related axonal swellings precede other neuropathological hallmarks in a knock-in mouse model of Huntington\u2019s disease","volume":"35","author":"Marangoni","year":"2014","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0220","doi-asserted-by":"crossref","first-page":"9455","DOI":"10.1523\/JNEUROSCI.4699-13.2014","article-title":"Huntingtin is required for normal excitatory synapse development in cortical and striatal circuits","volume":"34","author":"McKinstry","year":"2014","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0225","doi-asserted-by":"crossref","first-page":"e49838","DOI":"10.1371\/journal.pone.0049838","article-title":"Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington\u2019s disease: zQ175","volume":"7","author":"Menalled","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0230","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3389\/fnsys.2011.00026","article-title":"Dysregulated neuronal activity patterns implicate corticostriatal circuit dysfunction in multiple rodent models of Huntington\u2019s disease","volume":"5","author":"Miller","year":"2011","journal-title":"Front Syst Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0235","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1523\/JNEUROSCI.4538-13.2014","article-title":"Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spines","volume":"34","author":"Murphy","year":"2014","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0240","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.nbd.2014.08.009","article-title":"Genetic rescue of CB1 receptors on medium spiny neurons prevents loss of excitatory striatal synapses but not motor impairment in HD mice","volume":"71","author":"Naydenov","year":"2014","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0245","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.brainresrev.2010.03.004","article-title":"Electrophysiological measures as potential biomarkers in Huntington\u2019s disease: review and future directions","volume":"64","author":"Nguyen","year":"2010","journal-title":"Brain Res Rev"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0250","doi-asserted-by":"crossref","first-page":"4449","DOI":"10.1523\/JNEUROSCI.15-06-04449.1995","article-title":"Potassium currents responsible for inward and outward rectification in rat neostriatal spiny projection neurons","volume":"15","author":"Nisenbaum","year":"1995","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0255","doi-asserted-by":"crossref","first-page":"9909","DOI":"10.1523\/JNEUROSCI.0275-12.2012","article-title":"Beta reactivity, prospective facilitation of executive processing, and its dependence on dopaminergic therapy in Parkinson\u2019s disease","volume":"32","author":"Oswal","year":"2012","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0260","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1093\/brain\/awg119","article-title":"Progressive striatal and cortical dopamine receptor dysfunction in Huntington\u2019s disease: a PET study","volume":"126","author":"Pavese","year":"2003","journal-title":"Brain"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0265","unstructured":"Paxinos G, Franklin KBJ (2003) The Mouse Brain in Stereotaxic Coordinates. Elsevier."},{"key":"10.1016\/j.neuroscience.2015.10.039_b0270","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1016\/j.clinph.2012.01.012","article-title":"Abnormal spinal cord pain processing in Huntington\u2019s disease. The role of the diffuse noxious inhibitory control","volume":"123","author":"Perrotta","year":"2012","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0275","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1006\/nbdi.2002.0534","article-title":"Evidence for dysfunction of the nigrostriatal pathway in the R6\/1 line of transgenic Huntington\u2019s disease mice","volume":"11","author":"Petersen","year":"2002","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0280","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.neuron.2014.05.032","article-title":"Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington\u2019s disease","volume":"83","author":"Plotkin","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0285","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1038\/nn.2848","article-title":"Synaptically driven state transitions in distal dendrites of striatal spiny neurons","volume":"14","author":"Plotkin","year":"2011","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0290","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.conb.2015.01.020","article-title":"Corticostriatal synaptic adaptations in Huntington\u2019s disease","volume":"33C","author":"Plotkin","year":"2015","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0295","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1113\/jphysiol.1983.sp014885","article-title":"Amplitude fluctuations in synaptic potentials evoked in cat spinal motoneurones at identified group Ia synapses","volume":"343","author":"Redman","year":"1983","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0300","doi-asserted-by":"crossref","first-page":"5733","DOI":"10.1073\/pnas.85.15.5733","article-title":"Differential loss of striatal projection neurons in Huntington disease","volume":"85","author":"Reiner","year":"1988","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0305","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1002\/mds.25624","article-title":"Striatal parvalbuminergic neurons are lost in Huntington\u2019s disease: implications for dystonia","volume":"28","author":"Reiner","year":"2013","journal-title":"Mov Disord"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0310","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/ana.10691","article-title":"Predictors of neuropathological severity in 100 patients with Huntington\u2019s disease","volume":"54","author":"Rosenblatt","year":"2003","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0315","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/nrneurol.2014.24","article-title":"Huntington disease: natural history, biomarkers and prospects for therapeutics","volume":"10","author":"Ross","year":"2014","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0320","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.neuint.2011.12.009","article-title":"Neurochemical characterization of the striatum and the nucleus accumbens in L-type Ca(v)1.3 channels knockout mice","volume":"60","author":"Sagala","year":"2012","journal-title":"Neurochem Int"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0325","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/0306-4522(94)00427-7","article-title":"Evidence for a preferential loss of enkephalin immunoreactivity in the external globus pallidus in low grade Huntington\u2019s disease using high resolution image analysis","volume":"64","author":"Sapp","year":"1995","journal-title":"Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0330","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1093\/hmg\/ddr475","article-title":"Mutant huntingtin\u2019s interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington\u2019s disease","volume":"21","author":"Shirendeb","year":"2012","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0335","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.neuroscience.2004.02.026","article-title":"Learning a new behavioral strategy in the shuttle-box increases prefrontal dopamine","volume":"126","author":"Stark","year":"2004","journal-title":"Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0340","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.conb.2014.07.008","article-title":"Dopaminergic modulation of striatal networks in health and Parkinson\u2019s disease","volume":"29","author":"Surmeier","year":"2014","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0345","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.brainresrev.2007.10.008","article-title":"Feedforward and feedback inhibition in neostriatal GABAergic spiny neurons","volume":"58","author":"Tepper","year":"2008","journal-title":"Brain Res Rev"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0350","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.cell.2008.10.008","article-title":"The self-tuning neuron: synaptic scaling of excitatory synapses","volume":"135","author":"Turrigiano","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0355","doi-asserted-by":"crossref","first-page":"5938","DOI":"10.1523\/JNEUROSCI.5007-13.2014","article-title":"Corticostriatal coordination through coherent phase-amplitude coupling","volume":"34","author":"von Nicolai","year":"2014","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0360","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/S0140-6736(07)60111-1","article-title":"Huntington\u2019s disease","volume":"369","author":"Walker","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0365","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s10571-006-9053-9","article-title":"Three types of tyrosine hydroxylase-positive CNS neurons distinguished by dopa decarboxylase and VMAT2 co-expression","volume":"26","author":"Weihe","year":"2006","journal-title":"Cell Mol Neurobiol"},{"key":"10.1016\/j.neuroscience.2015.10.039_b0370","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1002\/mds.23695","article-title":"Milestones in research on the pathophysiology of Parkinson\u2019s disease","volume":"26","author":"Wichmann","year":"2011","journal-title":"Mov Disord"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452215009586?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452215009586?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T04:20:06Z","timestamp":1567311606000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452215009586"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":74,"alternative-id":["S0306452215009586"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2015.10.039","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]}}}