{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T08:43:42Z","timestamp":1769762622382,"version":"3.49.0"},"reference-count":86,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1016\/j.neuroscience.2016.02.021","type":"journal-article","created":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T20:40:28Z","timestamp":1455568828000},"page":"178-194","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Effects of developmental hyperserotonemia on the morphology of rat dentate nuclear neurons"],"prefix":"10.1016","volume":"322","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9432-9330","authenticated-orcid":false,"given":"L.H.","family":"Hough","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Segal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2016.02.021_b0005","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.tins.2007.12.005","article-title":"Neuroanatomy of autism","volume":"31","author":"Amaral","year":"2008","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0010","unstructured":"Association AP (2000) Diagnostic and statistical manual of mental disorders. Washington D.C."},{"issue":"5","key":"10.1016\/j.neuroscience.2016.02.021_b9025","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0361-9230(01)00614-1","article-title":"Modern views on an ancient chemical: serotonin effects on cell proliferation, maturation, and apoptosis","volume":"56","author":"Azmitia","year":"2001","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0015","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0006-8993(95)00051-Q","article-title":"5-HT1A agonist and dexamethasone reversal of para-chloroamphetamine induced loss of MAP-2 and synaptophysin immunoreactivity in adult rat brain","volume":"677","author":"Azmitia","year":"1995","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0020","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1002\/ar.21243","article-title":"Dystrophic serotonin axons in postmortem brains from young autism patients","volume":"294","author":"Azmitia","year":"2011","journal-title":"Anat Rec (Hoboken)"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0025","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.brainres.2013.11.032","article-title":"Cerebellar dentate nuclei lesions alter prefrontal cortex dendritic spine morphology","volume":"1544","author":"Bauer","year":"2014","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0030","doi-asserted-by":"crossref","first-page":"7594","DOI":"10.1523\/JNEUROSCI.14-12-07594.1994","article-title":"Effect of serotonin depletion on vibrissa-related patterns of thalamic afferents in the rat\u2019s somatosensory cortex","volume":"14","author":"Bennett-Clarke","year":"1994","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.02.021_b9005","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0091-679X(03)01017-3","article-title":"Biolistic transfection","volume":"71","author":"Bridgman","year":"2003","journal-title":"Methods Cell Biol"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0035","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0896-6273(00)80048-3","article-title":"Lack of barrels in the somatosensory cortex of monoamine oxidase A-deficient mice: role of a serotonin excess during the critical period","volume":"16","author":"Cases","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0040","series-title":"Cerebellar Dentate Nucleus-Organization Cytology, and Transmitters","author":"Chan-Palay","year":"1977"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0045","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1007\/BF01191453","article-title":"Effect of serotonin on the development of a rat cerebral cortex tissue culture","volume":"16","author":"Chubakov","year":"1986","journal-title":"Neurosci Behav Physiol"},{"issue":"3","key":"10.1016\/j.neuroscience.2016.02.021_b9000","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/BF01182928","article-title":"The stimulating influence of the raphe nuclei on the morphofunctional development of the hippocampus during their combined cultivation","volume":"23","author":"Chubakov","year":"1993","journal-title":"Neurosci Behav Physiol"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0050","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0278-5846(99)00022-6","article-title":"Evidence of altered energy metabolism in autistic children","volume":"23","author":"Chugani","year":"1999","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0055","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00439-006-0301-3","article-title":"Evidence for epistasis between SLC6A4 and ITGB3 in autism etiology and in the determination of platelet serotonin levels","volume":"121","author":"Coutinho","year":"2007","journal-title":"Hum Genet"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0060","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/BF01537618","article-title":"Imitation in autistic, early schizophrenic, and non-psychotic subnormal children","volume":"2","author":"DeMeyer","year":"1972","journal-title":"J Autism Childhood Schizophrenia"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0065","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0306-4522(02)00305-6","article-title":"Quantitative analysis of the dendritic morphology of corticocortical projection neurons in the macaque monkey association cortex","volume":"114","author":"Duan","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0070","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1093\/cercor\/13.9.950","article-title":"Age-related dendritic and spine changes in corticocortically projecting neurons in macaque monkeys","volume":"13","author":"Duan","year":"2003","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0075","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1210\/mend.12.7.0135","article-title":"Serotonergic repression of mitogen-activated protein kinase control of the calcitonin gene-related peptide enhancer","volume":"12","author":"Durham","year":"1998","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0080","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0165-3806(99)00036-X","article-title":"Synaptogenesis in the postnatal rat fascia dentata is influenced by 5-HT1a receptor activation","volume":"114","author":"Faber","year":"1999","journal-title":"Brain Res Dev Brain Res"},{"issue":"Pt 1","key":"10.1016\/j.neuroscience.2016.02.021_b0085","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1046\/j.1365-2788.1998.00065.x","article-title":"Clumsiness in autism and Asperger syndrome: a further report","volume":"42","author":"Ghaziuddin","year":"1998","journal-title":"J Intellect Disabil Res"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0090","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/cne.901210106","article-title":"Patterns of localization in the cerebellar corticonuclear projections of albino rat","volume":"121","author":"Goodman","year":"1963","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0095","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1365-2818.1987.tb02837.x","article-title":"The efficiency of systematic sampling in stereology and its prediction","volume":"147","author":"Gundersen","year":"1987","journal-title":"J Microsc"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0100","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1523\/JNEUROSCI.3440-05.2006","article-title":"Estrogen alters spine number and morphology in prefrontal cortex of aged female rhesus monkeys","volume":"26","author":"Hao","year":"2006","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0105","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/syn.890080404","article-title":"Calcitonin gene-related peptide in the amygdaloid complex of the rat: immunohistochemical and quantitative distribution, and drug effects on calcium dependent, potassium-evoked in vitro release","volume":"8","author":"Haring","year":"1991","journal-title":"Synapse"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0110","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF02276237","article-title":"Brief report: planning problems in autism at the level of motor control","volume":"26","author":"Hughes","year":"1996","journal-title":"J Autism Dev Disord"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0115","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1742-4682-2-27","article-title":"Statistical distribution of blood serotonin as a predictor of early autistic brain abnormalities","volume":"2","author":"Janusonis","year":"2005","journal-title":"Theor Biol Med Model"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0120","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1523\/JNEUROSCI.4651-03.2004","article-title":"Early serotonergic projections to Cajal-Retzius cells: relevance for cortical development","volume":"24","author":"Janusonis","year":"2004","journal-title":"J Neurosci"},{"issue":"3","key":"10.1016\/j.neuroscience.2016.02.021_b9020","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/S0026-895X(25)14792-5","article-title":"Tryptophan hydroxylase inhibition: the mechanism by which p-chlorophenylalanine depletes rat brain serotonin","volume":"3","author":"J\u00e9quier","year":"1967","journal-title":"Mol Pharmacol"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0125","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/BF01837897","article-title":"Motor imitation abilities and neurological signs in autistic children","volume":"15","author":"Jones","year":"1985","journal-title":"J Autism Dev Disord"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0130","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0031-9384(01)00673-4","article-title":"Behavioral and magnetic resonance spectroscopic studies in the rat hyperserotonemic model of autism","volume":"75","author":"Kahne","year":"2002","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0135","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.neures.2003.10.001","article-title":"Regulation of dendrite formation of Purkinje cells by serotonin through serotonin1A and serotonin2A receptors in culture","volume":"48","author":"Kondoh","year":"2004","journal-title":"Neurosci Res"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0140","first-page":"379","article-title":"On the ontogenetic development of the cerebellum (nuclei, fissures, and cortex) of the rat, with special reference to regional variations in corticogenesis","volume":"10","author":"Korneliussen","year":"1968","journal-title":"J Hirnforsch"},{"issue":"4","key":"10.1016\/j.neuroscience.2016.02.021_b0145","first-page":"35","article-title":"The biochemical and biobehavioral profile of 5-methoxytryptamine","volume":"12","author":"Koslow","year":"1976","journal-title":"Psychopharmacol Bull"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0150","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/978-1-4684-3860-4_28","article-title":"Roles for serotonin in neuroembryogenesis","volume":"133","author":"Lauder","year":"1981","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0155","first-page":"3","article-title":"Roles for serotonin in neurogenesis","volume":"9","author":"Lauder","year":"1983","journal-title":"Monogr Neural Sci"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0160","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1037\/0735-7044.100.4.443","article-title":"Does the cerebellum contribute to mental skills?","volume":"100","author":"Leiner","year":"1986","journal-title":"Behav Neurosci"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0165","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/0361-9230(82)90164-2","article-title":"Immunohistochemical study of the development of serotonergic neurons in the rat CNS","volume":"9","author":"Lidov","year":"1982","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0170","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/S0006-8993(97)00297-7","article-title":"Serotonin depletion during synaptogenesis leads to decreased synaptic density and learning deficits in the adult rat: a possible model of neurodevelopmental disorders with cognitive deficits","volume":"760","author":"Mazer","year":"1997","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0175","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.brainres.2007.10.063","article-title":"Further studies in the developmental hyperserotonemia model (DHS) of autism: social, behavioral and peptide changes","volume":"1189","author":"McNamara","year":"2008","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0180","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1046\/j.1460-9568.2000.00086.x","article-title":"Protein kinase C activity modulates dendritic differentiation of rat Purkinje cells in cerebellar slice cultures","volume":"12","author":"Metzger","year":"2000","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0185","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1258\/002367780780937571","article-title":"A simple tourniquet to aid mouse tail venipuncture","volume":"14","author":"Minasian","year":"1980","journal-title":"Lab Anim"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0190","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1017\/S1355617700677020","article-title":"Evidence for a deficit in procedural learning in children and adolescents with autism: implications for cerebellar contribution","volume":"6","author":"Mostofsky","year":"2000","journal-title":"J Int Neuropsychol Soc"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0195","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1017\/S1355617706060437","article-title":"Developmental dyspraxia is not limited to imitation in children with autism spectrum disorders","volume":"12","author":"Mostofsky","year":"2006","journal-title":"J Int Neuropsychol Soc"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0200","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1093\/brain\/awp088","article-title":"Decreased connectivity and cerebellar activity in autism during motor task performance","volume":"132","author":"Mostofsky","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0205","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0891-0618(94)90028-0","article-title":"Absolute number and size of pigmented locus coeruleus neurons in young and aged individuals","volume":"7","author":"Mouton","year":"1994","journal-title":"J Chem Neuroanat"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0210","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0304-3940(98)00151-7","article-title":"Impairment of dentato-thalamo-cortical pathway in autistic men: language activation data from positron emission tomography","volume":"245","author":"Muller","year":"1998","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0215","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0006-8993(00)02201-0","article-title":"Trophic interactions between brain-derived neurotrophic factor and s100beta on cultured serotonergic neurons","volume":"868","author":"Nishi","year":"2000","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0220","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s00787-002-0285-z","article-title":"Evaluation of neuromotor deficits in children with autism and children with a specific speech and language disorder","volume":"11","author":"Noterdaeme","year":"2002","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"10.1016\/j.neuroscience.2016.02.021_b9015","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1038\/nprot.2006.258","article-title":"Diolistic labeling of neuronal cultures and intact tissue using a hand-held gene gun","volume":"1","author":"O'Brien","year":"2006","journal-title":"Nature protocols"},{"key":"10.1016\/j.neuroscience.2016.02.021_b9010","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0165-0270(01)00457-5","article-title":"Modifications to the hand-held Gene Gun: improvements for in vitro biolistic transfection of organotypic neuronal tissue","volume":"112","author":"O'Brien","year":"2001","journal-title":"J Neurosci Methods"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0225","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/BF01486970","article-title":"Parental perception of behavioral symptoms in Japanese autistic children","volume":"17","author":"Ohta","year":"1987","journal-title":"J Autism Dev Disord"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0230","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1002\/neu.480240512","article-title":"Synaptic loss following removal of serotoninergic fibers in newly hatched and adult chickens","volume":"24","author":"Okado","year":"1993","journal-title":"J Neurobiol"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0235","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"2005"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0240","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1111\/j.1471-4159.1993.tb03166.x","article-title":"5-Hydroxytryptamine receptors","volume":"60","author":"Peroutka","year":"1993","journal-title":"J Neurochem"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0245","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/0197-0186(94)90151-1","article-title":"5-Hydroxytryptamine receptors in vertebrates and invertebrates: why are there so many?","volume":"25","author":"Peroutka","year":"1994","journal-title":"Neurochem Int"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0250","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neuroscience.2004.01.006","article-title":"Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex","volume":"125","author":"Radley","year":"2004","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0255","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.biopsych.2006.01.009","article-title":"Lack of evidence for association of the serotonin transporter gene SLC6A4 with autism","volume":"60","author":"Ramoz","year":"2006","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0260","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0169-328X(97)00317-3","article-title":"Environmental enrichment selectively increases 5-HT1A receptor mRNA expression and binding in the rat hippocampus","volume":"53","author":"Rasmuson","year":"1998","journal-title":"Brain Res Mol Brain Res"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0265","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0163-7258(01)00169-3","article-title":"Multiplicity of mechanisms of serotonin receptor signal transduction","volume":"92","author":"Raymond","year":"2001","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0270","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0165-3806(94)90167-8","article-title":"Neurotrophic effects of ipsapirone and other 5-HT1A receptor agonists on septal cholinergic neurons in culture","volume":"82","author":"Riad","year":"1994","journal-title":"Brain Res Dev Brain Res"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0275","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/mp.2008.89","article-title":"Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6","volume":"14","author":"Riccio","year":"2009","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0285","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1177\/1362361301005001007","article-title":"A deficit in shifting attention present in high-functioning autism but not Asperger\u2019s disorder","volume":"5","author":"Rinehart","year":"2001","journal-title":"Autism"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0290","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/S1046-2023(03)00011-2","article-title":"Automated reconstruction of three-dimensional neuronal morphology from laser scanning microscopy images","volume":"30","author":"Rodriguez","year":"2003","journal-title":"Methods"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0295","doi-asserted-by":"crossref","first-page":"2060","DOI":"10.2307\/1131609","article-title":"Imitation and pantomime in high-functioning adolescents with autism spectrum disorders","volume":"67","author":"Rogers","year":"1996","journal-title":"Child Dev"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0300","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1002\/(SICI)1097-0193(1996)4:3<174::AID-HBM3>3.0.CO;2-0","article-title":"From movement to thought: anatomic substrates of the cerebellar contribution to cognitive processing","volume":"4","author":"Schmahmann","year":"1996","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0305","doi-asserted-by":"crossref","DOI":"10.3791\/2081","article-title":"DiOLISTIC labeling of neurons from rodent and non-human primate brain slices","author":"Seabold","year":"2010","journal-title":"J Vis Exp"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0310","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0165-3806(91)90029-I","article-title":"Dose-related effects of prenatal 5-methoxytryptamine (5-MT) on development of serotonin terminal density and behavior","volume":"59","author":"Shemer","year":"1991","journal-title":"Brain Res Dev Brain Res"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0315","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1037\/0033-2909.116.2.259","article-title":"Imitation and action in autism: a critical review","volume":"116","author":"Smith","year":"1994","journal-title":"Psychol Bull"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0320","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1093\/cercor\/bhn031","article-title":"Diffusion tensor imaging of frontal lobe in autism spectrum disorder","volume":"18","author":"Sundaram","year":"2008","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0325","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/s10803-006-0340-6","article-title":"Predictors of optimal outcome in toddlers diagnosed with autism spectrum disorders","volume":"37","author":"Sutera","year":"2007","journal-title":"J Autism Dev Disord"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0330","doi-asserted-by":"crossref","first-page":"13982","DOI":"10.1073\/pnas.95.23.13982","article-title":"Movement analysis in infancy may be useful for early diagnosis of autism","volume":"95","author":"Teitelbaum","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0335","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/ajmg.10192","article-title":"Transmission disequilibrium studies of the serotonin 5-HT2A receptor gene (HTR2A) in autism","volume":"114","author":"Veenstra-VanderWeele","year":"2002","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0340","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1001\/archneur.1981.00510100074013","article-title":"Gait disturbances in patients with autistic behavior: a preliminary study","volume":"38","author":"Vilensky","year":"1981","journal-title":"Arch Neurol"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0345","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/j.1460-9568.2007.05661.x","article-title":"Embryonic depletion of serotonin affects cortical development","volume":"26","author":"Vitalis","year":"2007","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0350","series-title":"Understanding autism: from basic neuroscience to treatment","first-page":"175","article-title":"Language in Autism","author":"Walenski","year":"2006"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0355","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.neuroscience.2005.05.053","article-title":"New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales","volume":"136","author":"Wearne","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0360","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s00401-010-0655-4","article-title":"The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes","volume":"119","author":"Wegiel","year":"2010","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0365","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1002\/ar.1092310411","article-title":"Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator","volume":"231","author":"West","year":"1991","journal-title":"Anat Rec"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0370","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S0361-9230(01)00615-3","article-title":"Serotonin and brain development: role in human developmental diseases","volume":"56","author":"Whitaker-Azmitia","year":"2001","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0375","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0166-4328(96)00071-X","article-title":"Serotonin as a developmental signal","volume":"73","author":"Whitaker-Azmitia","year":"1996","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0380","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1001\/archneur.1980.00500610029003","article-title":"Autism and mental retardation: neuropathologic studies performed in four retarded persons with autistic behavior","volume":"37","author":"Williams","year":"1980","journal-title":"Arch Neurol"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0385","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0006-8993(97)01284-5","article-title":"Serotonin regulates synaptic connections in the dentate molecular layer of adult rats via 5-HT1a receptors: evidence for a glial mechanism","volume":"782","author":"Wilson","year":"1998","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0390","first-page":"51","article-title":"Serotonergic and catecholaminergic reuptake inhibitors have opposite effects on the ultrasonic isolation calls of rat pups","volume":"3","author":"Winslow","year":"1990","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0395","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S0022-3565(25)12578-0","article-title":"Serotonergic modulation of rat pup ultrasonic vocal development: studies with 3,4-methylenedioxymethamphetamine","volume":"254","author":"Winslow","year":"1990","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0400","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/cercor\/bhh016","article-title":"High-throughput morphometric analysis of individual neurons","volume":"14","author":"Wu","year":"2004","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.neuroscience.2016.02.021_b0405","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0165-3806(96)00175-7","article-title":"5-HT1a receptors mediate the neurotrophic effect of serotonin on developing dentate granule cells","volume":"98","author":"Yan","year":"1997","journal-title":"Brain Res Dev Brain Res"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452216001445?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452216001445?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T11:37:14Z","timestamp":1748777834000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452216001445"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":86,"alternative-id":["S0306452216001445"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2016.02.021","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2016,5]]}}}