{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:08:52Z","timestamp":1791198532648,"version":"4.1.0"},"reference-count":80,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.neuroscience.2016.05.027","type":"journal-article","created":{"date-parts":[[2016,5,22]],"date-time":"2016-05-22T20:10:24Z","timestamp":1463947824000},"page":"363-379","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["Early GABAergic transmission defects in the external globus pallidus and rest\/activity rhythm alteration in a mouse model of Huntington\u2019s disease"],"prefix":"10.1016","volume":"329","author":[{"given":"Zhuowei","family":"Du","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Chazalon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Bestaven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Leste-Lasserre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Baufreton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Ren\u00e9","family":"Cazalets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoon H.","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice","family":"Garret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2016.05.027_b0005","doi-asserted-by":"crossref","first-page":"6667","DOI":"10.1523\/JNEUROSCI.4662-14.2015","article-title":"Prototypic and arkypallidal neurons in the dopamine-intact external globus pallidus","volume":"35","author":"Abdi","year":"2015","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0010","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jchemneu.2009.02.001","article-title":"Cannabinoid (CB(1)), GABA(A) and GABA(B) receptor subunit changes in the globus pallidus in Huntington\u2019s disease","volume":"37","author":"Allen","year":"2009","journal-title":"J Chem Neuroanat"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0015","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1007\/s00429-014-0805-x","article-title":"Behavioral and neurophysiological evidence for the enhancement of cognitive control under dorsal pallidal deep brain stimulation in Huntington\u2019s disease","volume":"220","author":"Beste","year":"2015","journal-title":"Brain Struct Funct"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0020","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0079-6123(06)60013-7","article-title":"Localization of GABA receptors in the basal ganglia","volume":"160","author":"Boyes","year":"2007","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0025","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.neuron.2015.03.042","article-title":"The GABA receptor as a therapeutic target for neurodevelopmental disorders","volume":"86","author":"Braat","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0030","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.neuron.2011.12.012","article-title":"Extrasynaptic GABA(A) receptors: their function in the CNS and implications for disease","volume":"73","author":"Brickley","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0035","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.brainresbull.2011.01.010","article-title":"Longitudinal analysis of the behavioural phenotype in R6\/1 (C57BL\/6J) Huntington\u2019s disease transgenic mice","volume":"88","author":"Brooks","year":"2012","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0040","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.neuint.2009.01.020","article-title":"A novel mechanism for GABA synthesis and packaging into synaptic vesicles","volume":"55","author":"Buddhala","year":"2009","journal-title":"Neurochem Int"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0045","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1373\/clinchem.2008.112797","article-title":"The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments","volume":"55","author":"Bustin","year":"2009","journal-title":"Clin Chem"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0050","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1136\/jnnp.74.7.968","article-title":"Genetically confirmed clinical Huntington\u2019s disease with no observable cell loss","volume":"74","author":"Caramins","year":"2003","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0055","doi-asserted-by":"crossref","first-page":"9280","DOI":"10.1073\/pnas.1016190108","article-title":"Changes in striatal procedural memory coding correlate with learning deficits in a mouse model of Huntington disease","volume":"108","author":"Cayzac","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0060","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.neuron.2013.10.041","article-title":"Dopamine D2 receptors regulate the anatomical and functional balance of basal ganglia circuitry","volume":"81","author":"Cazorla","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0065","doi-asserted-by":"crossref","first-page":"7393","DOI":"10.1523\/JNEUROSCI.2137-12.2013","article-title":"Multiple sources of striatal inhibition are differentially affected in Huntington\u2019s disease mouse models","volume":"33","author":"Cepeda","year":"2013","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0070","doi-asserted-by":"crossref","first-page":"28254","DOI":"10.1074\/jbc.M113.470807","article-title":"Agonist-dependent endocytosis of gamma-aminobutyric acid type A (GABAA) receptors revealed by a gamma2(R43Q) epilepsy mutation","volume":"288","author":"Chaumont","year":"2013","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0075","article-title":"Identification of a direct GABAergic pallidocortical pathway in rodents","author":"Chen","year":"2015","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0080","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","article-title":"Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction","volume":"162","author":"Chomczynski","year":"1987","journal-title":"Anal Biochem"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0085","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0028-3908(01)00038-7","article-title":"Dopamine D2 receptor mediated presynaptic inhibition of striatopallidal GABA(A) IPSCs in vitro","volume":"41","author":"Cooper","year":"2001","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0090","article-title":"Circadian sleep\/wake rhythm abnormalities as a risk factor of a poststroke apathy","author":"Cosin","year":"2014","journal-title":"Int J Stroke"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0095","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.neuron.2010.12.035","article-title":"Huntington\u2019s disease: can mice lead the way to treatment?","volume":"69","author":"Crook","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0100","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1111\/j.1471-4159.2005.03588.x","article-title":"Selective deficits in the expression of striatal-enriched mRNAs in Huntington\u2019s disease","volume":"96","author":"Desplats","year":"2006","journal-title":"J Neurochem"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0105","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1177\/0748730411431550","article-title":"Rapid assessment of sleep-wake behavior in mice","volume":"27","author":"Fisher","year":"2012","journal-title":"J Biol Rhythms"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0110","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1093\/brain\/awt132","article-title":"Longitudinal analysis of the electroencephalogram and sleep phenotype in the R6\/2 mouse model of Huntington\u2019s disease","volume":"136","author":"Fisher","year":"2013","journal-title":"Brain"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0115","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3389\/fncir.2013.00153","article-title":"A method for the three-dimensional reconstruction of Neurobiotin-filled neurons and the location of their synaptic inputs","volume":"7","author":"Fogarty","year":"2013","journal-title":"Front Neural Circuits"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0120","doi-asserted-by":"crossref","first-page":"295","DOI":"10.3389\/fncel.2014.00295","article-title":"Possible involvement of self-defense mechanisms in the preferential vulnerability of the striatum in Huntington\u2019s disease","volume":"8","author":"Francelle","year":"2014","journal-title":"Front Cell Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0125","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.tins.2008.02.006","article-title":"Gephyrin: where do we stand, where do we go?","volume":"31","author":"Fritschy","year":"2008","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0130","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0079-6123(06)60017-4","article-title":"GABAergic circuits in the basal ganglia and movement disorders","volume":"160","author":"Galvan","year":"2007","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0135","doi-asserted-by":"crossref","first-page":"15178","DOI":"10.1523\/JNEUROSCI.3252-14.2014","article-title":"New roles for the external globus pallidus in Basal Ganglia circuits and behavior","volume":"34","author":"Gittis","year":"2014","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0140","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.smrv.2014.06.002","article-title":"A fresh look at the use of nonparametric analysis in actimetry","volume":"20C","author":"Goncalves","year":"2015","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0145","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s11910-010-0163-x","article-title":"Asymptomatic sleep abnormalities are a common early feature in patients with Huntington\u2019s disease","volume":"11","author":"Goodman","year":"2011","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0150","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1111\/j.1460-9568.2010.07552.x","article-title":"Differential localization of GABA(A) receptor subunits in relation to rat striatopallidal and pallidopallidal synapses","volume":"33","author":"Gross","year":"2011","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0155","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.neuroscience.2013.01.008","article-title":"Patterns of mRNA and protein expression for 12 GABAA receptor subunits in the mouse brain","volume":"236","author":"Hortnagl","year":"2013","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0160","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1093\/brain\/awt128","article-title":"Progressive sleep and electroencephalogram changes in mice carrying the Huntington\u2019s disease mutation","volume":"136","author":"Kantor","year":"2013","journal-title":"Brain"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0165","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0006-8993(94)90950-4","article-title":"Parvalbumin-immunopositive neurons in rat globus pallidus: a light and electron microscopic study","volume":"657","author":"Kita","year":"1994","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0170","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.expneurol.2010.12.011","article-title":"Dysfunctions in circadian behavior and physiology in mouse models of Huntington\u2019s disease","volume":"228","author":"Kudo","year":"2011","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0175","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1093\/hmg\/ddm133","article-title":"Mutant huntingtin\u2019s effects on striatal gene expression in mice recapitulate changes observed in human Huntington\u2019s disease brain and do not differ with Mutant huntingtin length or wild-type huntingtin dosage","volume":"16","author":"Kuhn","year":"2007","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0180","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1002\/ana.24495","article-title":"Sleep deficits but no metabolic deficits in premanifest Huntington\u2019s disease","volume":"78","author":"Lazar","year":"2015","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0185","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.conb.2013.02.001","article-title":"Role of the basal ganglia in the control of sleep and wakefulness","volume":"23","author":"Lazarus","year":"2013","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0190","doi-asserted-by":"crossref","first-page":"e0126972","DOI":"10.1371\/journal.pone.0126972","article-title":"Sleep physiology alterations precede plethoric phenotypic changes in R6\/1 Huntington\u2019s disease mice","volume":"10","author":"Lebreton","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0195","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/jcbfm.2010.186","article-title":"External globus pallidus stimulation modulates brain connectivity in Huntington\u2019s disease","volume":"31","author":"Ligot","year":"2011","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0200","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0205","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.neuron.2011.03.024","article-title":"GABAA receptor trafficking-mediated plasticity of inhibitory synapses","volume":"70","author":"Luscher","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0210","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.neuron.2012.04.027","article-title":"Dichotomous organization of the external globus pallidus","volume":"74","author":"Mallet","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0215","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1602\/neurorx.2.3.465","article-title":"Knock-in mouse models of Huntington\u2019s disease","volume":"2","author":"Menalled","year":"2005","journal-title":"NeuroRx"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0220","doi-asserted-by":"crossref","first-page":"5861","DOI":"10.1113\/jphysiol.2012.241331","article-title":"Altered pallido-pallidal synaptic transmission leads to aberrant firing of globus pallidus neurons in a rat model of Parkinson\u2019s disease","volume":"590","author":"Miguelez","year":"2012","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0225","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.tins.2010.08.002","article-title":"Early synaptic pathophysiology in neurodegeneration: insights from Huntington\u2019s disease","volume":"33","author":"Milnerwood","year":"2010","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0230","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1093\/hmg\/ddl092","article-title":"Early development of aberrant synaptic plasticity in a mouse model of Huntington\u2019s disease","volume":"15","author":"Milnerwood","year":"2006","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0235","first-page":"94","article-title":"An autopsy case with clinically and molecular genetically diagnosed Huntington\u2019s disease with only minimal non-specific neuropathological findings","volume":"19","author":"Mizuno","year":"2000","journal-title":"Clin Neuropathol"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0240","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.tins.2004.07.002","article-title":"Diversity of inhibitory neurotransmission through GABA(A) receptors","volume":"27","author":"Mody","year":"2004","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0245","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/j.neuropharm.2010.10.020","article-title":"The rise of a new GABA pharmacology","volume":"60","author":"Mohler","year":"2011","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0250","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0306-4522(02)00033-7","article-title":"Localisation of GABA(A) receptor epsilon-subunit in cholinergic and aminergic neurones and evidence for co-distribution with the theta-subunit in rat brain","volume":"111","author":"Moragues","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0255","first-page":"1","article-title":"GABA potency at GABA(A) receptors found in synaptic and extrasynaptic zones","volume":"6","author":"Mortensen","year":"2011","journal-title":"Front Cell Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0260","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.expneurol.2012.10.014","article-title":"Circadian and sleep disorder in Huntington\u2019s disease","volume":"243","author":"Morton","year":"2013","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0265","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1523\/JNEUROSCI.3842-04.2005","article-title":"Disintegration of the sleep-wake cycle and circadian timing in Huntington\u2019s disease","volume":"25","author":"Morton","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0270","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3389\/fnsys.2015.00032","article-title":"Preserving cortico-striatal function: deep brain stimulation in Huntington\u2019s disease","volume":"9","author":"Nagel","year":"2015","journal-title":"Front Syst Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0275","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1152\/physiolgenomics.00139.2006","article-title":"Novel method for high-throughput phenotyping of sleep in mice","volume":"28","author":"Pack","year":"2007","journal-title":"Physiol Genomics"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0280","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1093\/hmg\/ddn385","article-title":"Altered serotonin receptor expression is associated with depression-related behavior in the R6\/1 transgenic mouse model of Huntington\u2019s disease","volume":"18","author":"Pang","year":"2009","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0285","article-title":"Chronic cannabinoid receptor stimulation selectively prevents motor impairments in a mouse model of Huntington\u2019s disease","author":"Pietropaolo","year":"2014","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0290","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/nrn3570","article-title":"Choosing an animal model for the study of Huntington\u2019s disease","volume":"14","author":"Pouladi","year":"2013","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0295","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.neuron.2009.08.023","article-title":"Neuroligin 2 drives postsynaptic assembly at perisomatic inhibitory synapses through gephyrin and collybistin","volume":"63","author":"Poulopoulos","year":"2009","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0300","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.1460-9568.2009.07062.x","article-title":"Basal ganglia control of sleep-wake behavior and cortical activation","volume":"31","author":"Qiu","year":"2010","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0305","doi-asserted-by":"crossref","first-page":"e84726","DOI":"10.1371\/journal.pone.0084726","article-title":"Correlations of behavioral deficits with brain pathology assessed through longitudinal MRI and histopathology in the R6\/1 mouse model of Huntington\u2019s disease","volume":"8","author":"Rattray","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0310","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1002\/mds.23136","article-title":"Hypokinesia in Huntington\u2019s disease co-occurs with cognitive and global dysfunctioning","volume":"25","author":"Reedeker","year":"2010","journal-title":"Mov Disord"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0315","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.expneurol.2003.11.002","article-title":"Can lesions of GPe correct HD deficits?","volume":"186","author":"Reiner","year":"2004","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0320","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/nrneurol.2014.24","article-title":"Huntington disease: natural history, biomarkers and prospects for therapeutics","volume":"10","author":"Ross","year":"2014","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0325","article-title":"GABA receptor subtypes: therapeutic potential in Down syndrome, affective disorders, schizophrenia, and autism","author":"Rudolph","year":"2013","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0330","doi-asserted-by":"crossref","first-page":"6352","DOI":"10.1523\/JNEUROSCI.0953-07.2007","article-title":"A single-cell analysis of intrinsic connectivity in the rat globus pallidus","volume":"27","author":"Sadek","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0335","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/nature14179","article-title":"A direct GABAergic output from the basal ganglia to frontal cortex","volume":"521","author":"Saunders","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0340","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1038\/nprot.2006.265","article-title":"Immunofluorescence in brain sections: simultaneous detection of presynaptic and postsynaptic proteins in identified neurons","volume":"1","author":"Schneider Gasser","year":"2006","journal-title":"Nat Protoc"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0345","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.nbd.2011.07.001","article-title":"What have we learned from gene expression profiles in Huntington\u2019s disease?","volume":"45","author":"Seredenina","year":"2012","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0350","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1111\/j.1460-9568.2008.06546.x","article-title":"Functional characterization of GABAergic pallidopallidal and striatopallidal synapses in the rat globus pallidus in vitro","volume":"28","author":"Sims","year":"2008","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0355","doi-asserted-by":"crossref","first-page":"3119","DOI":"10.1093\/hmg\/ddl252","article-title":"Cholinergic neuronal defect without cell loss in Huntington\u2019s disease","volume":"15","author":"Smith","year":"2006","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0360","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.expneurol.2008.01.023","article-title":"Pallidal neuronal discharge in Huntington\u2019s disease: support for selective loss of striatal cells originating the indirect pathway","volume":"211","author":"Starr","year":"2008","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0365","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.neulet.2006.07.036","article-title":"Motor and cognitive improvement by deep brain stimulation in a transgenic rat model of Huntington\u2019s disease","volume":"406","author":"Temel","year":"2006","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0370","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0079-6123(06)60001-0","article-title":"Basal ganglia macrocircuits","volume":"160","author":"Tepper","year":"2007","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0375","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1074\/mcp.M400055-MCP200","article-title":"Integrated genomic and proteomic analyses of gene expression in Mammalian cells","volume":"3","author":"Tian","year":"2004","journal-title":"Mol Cell Proteomics"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0380","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/(SICI)1096-9861(19991220)415:3<313::AID-CNE2>3.0.CO;2-7","article-title":"Regional and cellular localisation of GABA(A) receptor subunits in the human basal ganglia: An autoradiographic and immunohistochemical study","volume":"415","author":"Waldvogel","year":"1999","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0385","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1093\/hmg\/11.6.633","article-title":"Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice","volume":"11","author":"Wheeler","year":"2002","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0390","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/BF00314781","article-title":"Nocturnal sleep in Huntington\u2019s disease","volume":"238","author":"Wiegand","year":"1991","journal-title":"J Neurol"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0395","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/nrn2868","article-title":"Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease","volume":"11","author":"Wulff","year":"2010","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.027_b0400","article-title":"The utilisation of operant delayed matching and non-matching to position for probing cognitive flexibility and working memory in mouse models of Huntington\u2019s disease","author":"Yhnell","year":"2015","journal-title":"J Neurosci Methods"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452216301762?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452216301762?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,29]],"date-time":"2019-04-29T16:55:07Z","timestamp":1556556907000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452216301762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":80,"alternative-id":["S0306452216301762"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2016.05.027","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]}}}