{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:54:01Z","timestamp":1791399241395,"version":"4.3.3"},"reference-count":78,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000145","name":"Alberta Innovates-Health Solutions Interdisciplinary Team","doi-asserted-by":"crossref","award":["200700595"],"award-info":[{"award-number":["200700595"]}],"id":[{"id":"10.13039\/501100000145","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["102652"],"award-info":[{"award-number":["102652"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"National Sciences and Engineering Research Council of Canada","doi-asserted-by":"crossref","award":["327364-06"],"award-info":[{"award-number":["327364-06"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000038","name":"National Sciences and Engineering Research Council of Canada","doi-asserted-by":"crossref","award":["298194-20009"],"award-info":[{"award-number":["298194-20009"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"crossref"}]},{"name":"CREATE","award":["371155"],"award-info":[{"award-number":["371155"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.neuroscience.2016.05.046","type":"journal-article","created":{"date-parts":[[2016,5,29]],"date-time":"2016-05-29T01:04:00Z","timestamp":1464483840000},"page":"79-89","source":"Crossref","is-referenced-by-count":47,"special_numbering":"C","title":["Altered brain morphology and functional connectivity reflect a vulnerable affective state after cumulative multigenerational stress in rats"],"prefix":"10.1016","volume":"330","author":[{"given":"J. Keiko","family":"McCreary","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. Sorina","family":"Truica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Becky","family":"Friesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youli","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Olson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Kovalchuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert R.","family":"Cross","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerlinde A.S.","family":"Metz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2016.05.046_b0005","doi-asserted-by":"crossref","first-page":"e12486","DOI":"10.1371\/journal.pone.0012486","article-title":"Ephrin-A5 and EphA5 interaction induces synaptogenesis during early hippocampal development","volume":"5","author":"Akaneya","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroscience.2016.05.046_b9005","doi-asserted-by":"crossref","DOI":"10.1093\/cercor\/bhw063","article-title":"Ancestral Exposure to Stress Generates New Behavioral Traits and a Functional Hemispheric Dominance Shift","author":"Ambeskovic","year":"2016","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0010","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.neuroimage.2004.03.031","article-title":"In vivo detection of neuroarchitecture in the rodent brain using manganese-enhanced MRI","volume":"22","author":"Aoki","year":"2004","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0015","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.brainres.2012.01.038","article-title":"Epigenetic programming of neurodegenerative diseases by an adverse environment","volume":"1444","author":"Babenko","year":"2012","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0020","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.physbeh.2013.04.008","article-title":"Manganese-enhanced magnetic resonance imaging (MEMRI) reveals brain circuitry involved in responding to an acute novel stress in rats with a history of repeated social stress","volume":"1","author":"Bangasser","year":"2013","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0025","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.neuroscience.2011.07.048","article-title":"Prenatal stress and neonatal handling induce sex-specific changes in dendritic complexity and dendritic spine density in hippocampal subregions of prepubertal rats","volume":"193","author":"Bock","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0030","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0079-6123(07)67012-5","article-title":"Structural and functional plasticity of the human brain in posttraumatic stress disorder","volume":"167","author":"Bremner","year":"2008","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0035","first-page":"H269","article-title":"Cerebral blood-flow and energy-metabolism during stress","volume":"259","author":"Bryan","year":"1990","journal-title":"Am J Physiol"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0040","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.1523\/JNEUROSCI.4372-06.2007","article-title":"The prefrontal cortex as a key target of the maladaptive response to stress","volume":"27","author":"Cerqueira","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0045","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3389\/neuro.08.019.2009","article-title":"Prenatal stress, glucocorticoids and the programming of adult disease","volume":"3","author":"Cottrell","year":"2009","journal-title":"Front Behav Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0050","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0006-8993(95)00087-7","article-title":"Prenatal stress increases corticotropin-releasing factor (CRF) content and release in rat amygdala minces","volume":"675","author":"Cratty","year":"1995","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0055","doi-asserted-by":"crossref","first-page":"9143","DOI":"10.1073\/pnas.1118514109","article-title":"Epigenetic transgenerational inheritance of altered stress responses","volume":"109","author":"Crews","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0060","doi-asserted-by":"crossref","first-page":"e92132","DOI":"10.1371\/journal.pone.0092132","article-title":"Lifespan psychomotor behaviour profiles of multigenerational prenatal stress and artificial food dye effects in rats","volume":"9","author":"Erickson","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0065","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.yhbeh.2013.11.007","article-title":"Stress inhibits psychomotor performance differently in simple and complex open field environments","volume":"65","author":"Faraji","year":"2014","journal-title":"Horm Behav"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0070","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.biopsych.2010.05.036","article-title":"Epigenetic transmission of the impact of early stress across generations","volume":"68","author":"Franklin","year":"2010","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0075","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.jpsychires.2010.01.006","article-title":"Interaction of childhood stress with hippocampus and prefrontal cortex volume reduction in major depression","volume":"44","author":"Frodl","year":"2010","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0080","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1093\/cercor\/1.5.418","article-title":"The effect of medial frontal cortex lesions on respiration, \u201cfreezing,\u201d and ultrasonic vocalizations during conditioned emotional responses in rats","volume":"1","author":"Frysztak","year":"1991","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0085","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/nn.3695","article-title":"Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice","volume":"17","author":"Gapp","year":"2014","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0090","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1258\/002367780780937454","article-title":"Stress response of rats to handling and experimental procedures","volume":"14","author":"Gartner","year":"1980","journal-title":"Lab Anim"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0095","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.psyneuen.2008.10.005","article-title":"Association between maternal and amniotic fluid cortisol is moderated by maternal anxiety","volume":"34","author":"Glover","year":"2009","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0100","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.jpsychires.2010.10.014","article-title":"Reduced hippocampus volume in the mouse model of Posttraumatic Stress Disorder","volume":"45","author":"Golub","year":"2011","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0105","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1080\/00401706.1972.10488981","article-title":"Extension of sample sizes and percentage points for significance tests of outlying observations","volume":"14","author":"Grubbs","year":"1972","journal-title":"Technometrics"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0110","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1037\/h0071444","article-title":"Emotional behavior in the rat I Defecation and urination as measures of individual differences in emotionality","volume":"18","author":"Hall","year":"1934","journal-title":"J Comp Psychol"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0115","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2478\/ngi-2013-0001","article-title":"Non-genetic inheritance of behaviour and stress resilience","volume":"1","author":"Hao","year":"2013","journal-title":"Non-Genet Inheritance"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0120","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1038\/sj.npp.1300910","article-title":"Anxiety and hippocampus volume in the rat","volume":"31","author":"Kalisch","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0125","article-title":"Elevated magnetic-resonance T2 relaxation-time as a marker of hippocampal pathology in temporal-lobe epilepsy \u2013 a comparison to Alzheimers-disease","volume":"45","author":"Kalviainen","year":"1995","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0130","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/j.1460-9568.2011.07968.x","article-title":"Increased stress reactivity is associated with reduced hippocampal activity and neuronal integrity along with changes in energy metabolism","volume":"35","author":"Knapman","year":"2012","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0135","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1365-2826.1991.tb00245.x","article-title":"Sex-related differences in dendritic branching of cells in the prefrontal cortex of rats","volume":"3","author":"Kolb","year":"1991","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0140","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.mcn.2012.03.005","article-title":"The dendritic tree and brain disorders","volume":"50","author":"Kulkarni","year":"2012","journal-title":"Mol Cell Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0145","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/S0730-725X(03)00189-9","article-title":"Magnetization transfer and T2 quantitation in normal appearing cortical gray matter and white matter adjacent to focal abnormality in patients with traumatic brain injury","volume":"21","author":"Kumar","year":"2003","journal-title":"Magn Reson Imaging"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0150","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1002\/jmri.20285","article-title":"In vivo measurements of T1 relaxation times in mouse brain associated with different modes of systemic administration of manganese chloride","volume":"21","author":"Kuo","year":"2005","journal-title":"J Magn Reson Imaging"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0155","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/0197-4580(96)00036-X","article-title":"MR T2 relaxometry in Alzheimer\u2019s disease and age-associated memory impairment","volume":"17","author":"Laakso","year":"1996","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0160","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1097\/WNR.0b013e328332bb09","article-title":"Chronic stress selectively reduces hippocampal volume in rats: a longitudinal magnetic resonance imaging study","volume":"20","author":"Lee","year":"2009","journal-title":"NeuroReport"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0165","doi-asserted-by":"crossref","first-page":"11032","DOI":"10.1073\/pnas.97.20.11032","article-title":"Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus","volume":"97","author":"Lemaire","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0170","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.neuint.2011.01.002","article-title":"Prenatal stress in rat causes long-term spatial memory deficit and hippocampus MRI abnormality: differential effects of postweaning enriched environment","volume":"58","author":"Lui","year":"2011","journal-title":"Neurochem Int"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0175","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/1471-244X-8-71","article-title":"Acute maternal stress in pregnancy and schizophrenia in offspring: a cohort prospective study","volume":"8","author":"Malaspina","year":"2008","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0180","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0079-6123(08)62128-7","article-title":"Protective and damaging effects of stress mediators: central role of the brain","volume":"122","author":"McEwen","year":"2000","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0185","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1002\/bies.201400217","article-title":"Ancestral experience as a game changer in stress vulnerability and disease outcomes","volume":"37","author":"Metz","year":"2015","journal-title":"BioEssays"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0190","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3389\/fgene.2011.00028","article-title":"Epigenetic memory in mammals","volume":"2","author":"Migicovsky","year":"2011","journal-title":"Front Genet"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0195","doi-asserted-by":"crossref","first-page":"11748","DOI":"10.1523\/JNEUROSCI.1887-11.2011","article-title":"Early prenatal stress epigenetically programs dysmasculinization in second-generation offspring via the paternal lineage","volume":"31","author":"Morgan","year":"2011","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0200","doi-asserted-by":"crossref","first-page":"9055","DOI":"10.1523\/JNEUROSCI.1424-08.2008","article-title":"Sex-specific programming of offspring emotionality after stress early in pregnancy","volume":"28","author":"Mueller","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0205","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1111\/j.1460-9568.2006.05024.x","article-title":"Changes of spine density and dendritic complexity in the prefrontal cortex in offspring of mothers exposed to stress during pregnancy","volume":"24","author":"Murmu","year":"2006","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.046_b9010","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.brainres.2011.07.023","article-title":"Prenatal bystander stress induces neuroanatomical changes in the prefrontal cortex and hippocampus of developing rat offspring","volume":"1412","author":"Mychasiuk","year":"2011","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0210","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1002\/syn.21512","article-title":"Prenatal stress alters dendritic morphology and synaptic connectivity in the prefrontal cortex and hippocampus of developing offspring","volume":"66","author":"Mychasiuk","year":"2012","journal-title":"Synapse"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0215","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0896-6273(02)00653-0","article-title":"Neurobiology of depression","volume":"34","author":"Nestler","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0220","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0006-3223(02)01405-1","article-title":"Preclinical models: status of basic research in depression","volume":"52","author":"Nestler","year":"2002","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0225","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.biopsych.2011.05.014","article-title":"Magnetic resonance imaging and spectroscopy reveal differential hippocampal changes in anhedonic and resilient subtypes of the chronic mild stress rat model","volume":"70","author":"Palacios","year":"2011","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0230","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"1998"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0235","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1074\/mcp.M113.031716","article-title":"A cell surface biotinylation assay to reveal membrane-associated neuronal cues: Negr1 regulates dendritic arborization","volume":"13","author":"Pischedda","year":"2014","journal-title":"Mol Cell Proteomics"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0240","doi-asserted-by":"crossref","first-page":"6225","DOI":"10.1523\/JNEUROSCI.20-16-06225.2000","article-title":"The role of ventromedial prefrontal cortex in the recovery of extinguished fear","volume":"20","author":"Quirk","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0245","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1093\/cercor\/bhi044","article-title":"Regional brain changes in aging healthy adults: general trends, individual differences and modifiers","volume":"15","author":"Raz","year":"2005","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0250","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/00012272-200510000-00006","article-title":"Effects of maternal prenatal stress on infant outcomes: a synthesis of the literature","volume":"28","author":"Ruiz","year":"2005","journal-title":"ANS Adv Nurs Sci"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0255","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1002\/nbm.945","article-title":"Manganese-enhanced magnetic resonance imaging (MEMRI): methodological and practical considerations","volume":"17","author":"Silva","year":"2004","journal-title":"NMR Biomed"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0260","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.neuroscience.2015.01.009","article-title":"Multigenerational prenatal stress increases the coherence of brain signaling among cortico-striatal-limbic circuits in adult rats","volume":"289","author":"Skelin","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0265","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.reprotox.2007.09.001","article-title":"What is an epigenetic transgenerational phenotype? F3 or F2","volume":"25","author":"Skinner","year":"2008","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0270","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0166-4328(94)90100-7","article-title":"Water maze performance and hippocampal weight of prenatally stressed rats","volume":"65","author":"Szuran","year":"1994","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0275","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0736-5748(98)00020-3","article-title":"Prenatal stress: consequences of glucocorticoids on hippocampal development and function","volume":"16","author":"Takahashi","year":"1998","journal-title":"Int J Dev Neurosci"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0280","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/BF03164770","article-title":"125I-iomazenil binding shows stress- and\/or diazepam-induced reductions in mouse brain: supporting data for 123I-iomazenil SPECT study of anxiety disorders","volume":"11","author":"Takahashi","year":"1997","journal-title":"Ann Nucl Med"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0285","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S0306-4530(98)00024-9","article-title":"Prolonged stress-induced elevation in plasma corticosterone during pregnancy in the rat: implications for prenatal stress studies","volume":"23","author":"Takahashi","year":"1998","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0290","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/cne.21071","article-title":"Synapse loss from chronically elevated glucocorticoids: relationship to neuropil volume and cell number in hippocampal area CA3","volume":"498","author":"Tata","year":"2006","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0295","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1038\/ncomms3136","article-title":"SNAP-25 regulates spine formation through postsynaptic binding to p140Cap","volume":"4","author":"Tomasoni","year":"2013","journal-title":"Nat Commun"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0300","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.neuron.2012.08.037","article-title":"The fibroblast growth factor family: neuromodulation of affective behavior","volume":"76","author":"Turner","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0305","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1006\/hbeh.1994.1030","article-title":"Neurotoxicity of glucocorticoids in the primate brain","volume":"28","author":"Uno","year":"1994","journal-title":"Horm Behav"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0310","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/j.euroneuro.2012.09.011","article-title":"Vulnerability versus resilience to prenatal stress in male and female rats; implications from gene expression profiles in the hippocampus and frontal cortex","volume":"23","author":"Van den Hove","year":"2013","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0315","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1002\/nbm.936","article-title":"Applications of manganese-enhanced magnetic resonance imaging (MEMRI) to image brain plasticity in song birds","volume":"17","author":"Van der Linden","year":"2004","journal-title":"NMR Biomed"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0320","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s11910-010-0104-8","article-title":"Synapse pathology in psychiatric and neurologic disease","volume":"10","author":"van Spronsen","year":"2010","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0325","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1111\/1471-0528.12136","article-title":"Transgenerational effects of prenatal exposure to the 1944\u201345 Dutch famine","volume":"120","author":"Veenendaal","year":"2013","journal-title":"BJOG"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0330","doi-asserted-by":"crossref","first-page":"3019","DOI":"10.1097\/00001756-200110080-00008","article-title":"Neonatal novelty exposure modulates hippocampal volumetric asymmetry in the rat","volume":"12","author":"Verstynen","year":"2001","journal-title":"NeuroReport"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0335","doi-asserted-by":"crossref","first-page":"6810","DOI":"10.1523\/JNEUROSCI.22-15-06810.2002","article-title":"Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons","volume":"22","author":"Vyas","year":"2002","journal-title":"J Neurosci"},{"issue":"Suppl. 1","key":"10.1016\/j.neuroscience.2016.05.046_b0340","doi-asserted-by":"crossref","first-page":"S9","DOI":"10.1186\/1471-2393-13-S1-S9","article-title":"Transgenerational programming of maternal behaviour by prenatal stress","volume":"13","author":"Ward","year":"2013","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0345","doi-asserted-by":"crossref","first-page":"e64154","DOI":"10.1371\/journal.pone.0064154","article-title":"A longitudinal study of hand motor recovery after sub-acute stroke: a study combined FMRI with diffusion tensor imaging","volume":"8","author":"Wei","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0350","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0301-0082(01)00018-1","article-title":"Alterations induced by gestational stress in brain morphology and behaviour of the offspring","volume":"65","author":"Weinstock","year":"2001","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0355","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S0892-0362(99)00038-0","article-title":"Stress during pregnancy alters the offspring hypothalamic, pituitary, adrenal, and testicular response to isolation on the day of weaning","volume":"21","author":"Williams","year":"1999","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0360","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.cell.2009.07.036","article-title":"Estrogen masculinizes neural pathways and sex-specific behaviors","volume":"139","author":"Wu","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0365","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/s12916-014-0121-6","article-title":"Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes","volume":"12","author":"Yao","year":"2014","journal-title":"BMC Med"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0370","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/BF00317655","article-title":"A quantitative approach to cytoarchitectonics. VI. The areal pattern of the cortex of the albino rat","volume":"159","author":"Zilles","year":"1980","journal-title":"Anat Embryol (Berl)"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0375","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3389\/fgene.2012.00096","article-title":"The secret language of destiny: stress imprinting and transgenerational origins of disease","volume":"3","author":"Zucchi","year":"2012","journal-title":"Front Genet"},{"key":"10.1016\/j.neuroscience.2016.05.046_b0380","doi-asserted-by":"crossref","first-page":"e56967","DOI":"10.1371\/journal.pone.0056967","article-title":"Maternal stress induces epigenetic signatures of psychiatric and neurological diseases in the offspring","volume":"8","author":"Zucchi","year":"2013","journal-title":"PLoS One"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452216302056?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452216302056?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T00:59:31Z","timestamp":1567990771000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452216302056"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":78,"alternative-id":["S0306452216302056"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2016.05.046","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]}}}