{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T04:17:08Z","timestamp":1789877828638,"version":"4.0.1"},"reference-count":88,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1016\/j.neuroscience.2017.04.047","type":"journal-article","created":{"date-parts":[[2017,5,10]],"date-time":"2017-05-10T05:16:20Z","timestamp":1494393380000},"page":"84-100","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Human neural stem\/progenitor cells derived from the olfactory epithelium express the TrkB receptor and migrate in response to BDNF"],"prefix":"10.1016","volume":"355","author":[{"given":"Leonardo","family":"Ortiz-L\u00f3pez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Julio","family":"Gonz\u00e1lez-Olvera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelly Maritza","family":"Vega-Rivera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Garc\u00eda-Anaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Karen","family":"Carapia-Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio C\u00e9sar","family":"Vel\u00e1zquez-Escobar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerardo Bernab\u00e9","family":"Ram\u00edrez-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2017.04.047_b0005","doi-asserted-by":"crossref","first-page":"5765","DOI":"10.1523\/JNEUROSCI.15-08-05765.1995","article-title":"BDNF enhances the differentiation but not the survival of CNS stem cell-derived neuronal precursors","volume":"15","author":"Ahmed","year":"1995","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0010","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1038\/nn735","article-title":"Visualizing synapse formation in arborizing optic axons in vivo: dynamics and modulation by BDNF","volume":"4","author":"Alsina","year":"2001","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0015","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1042\/BST20140172","article-title":"Tuning the signalling output of protein kinase C","volume":"42","author":"Antal","year":"2014","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0020","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1111\/j.1749-6632.1998.tb10656.x","article-title":"Cellular and molecular neuropathology of the olfactory epithelium and central olfactory pathways in Alzheimer's disease and schizophrenia","volume":"855","author":"Arnold","year":"1998","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0025","first-page":"49","article-title":"Synaptic network activity induces neuronal differentiation of adult hippocampal precursor cells through BDNF signaling","volume":"3","author":"Babu","year":"2009","journal-title":"Front Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0030","first-page":"45","article-title":"Neurotrophins: a family of proteins supporting the survival of neurons","volume":"390","author":"Barde","year":"1994","journal-title":"Prog Clin Biol Res"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0035","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jneumeth.2011.07.009","article-title":"A non-invasive method to isolate the neuronal linage from the nasal epithelium from schizophrenic and bipolar diseases","volume":"201","author":"Benitez-King","year":"2011","journal-title":"J Neurosci Methods"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0040","doi-asserted-by":"crossref","first-page":"7398","DOI":"10.1038\/sj.onc.1204899","article-title":"Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells","volume":"20","author":"Besson","year":"2001","journal-title":"Oncogene"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0045","doi-asserted-by":"crossref","first-page":"e15590","DOI":"10.1371\/journal.pone.0015590","article-title":"Olfactory stem cells, a new cellular model for studying molecular mechanisms underlying familial dysautonomia","volume":"5","author":"Boone","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0050","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1242\/dev.129.6.1435","article-title":"BDNF stimulates migration of cerebellar granule cells","volume":"129","author":"Borghesani","year":"2002","journal-title":"Development"},{"issue":"Suppl. 1","key":"10.1016\/j.neuroscience.2017.04.047_b0055","doi-asserted-by":"crossref","first-page":"i144","DOI":"10.1093\/chemse\/bjh155","article-title":"Olfactory subsystems in mammals: specific roles in recognizing chemical signals?","volume":"30","author":"Breer","year":"2005","journal-title":"Chem Senses"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0060","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0306-4522(98)00270-X","article-title":"Alterations in expression of the neurotrophic factors, glial cell line-derived neurotrophic factor, ciliary neurotrophic factor and brain-derived neurotrophic factor, in the target-deprived olfactory neuroepithelium","volume":"90","author":"Buckland","year":"1999","journal-title":"Neuroscience"},{"issue":"4","key":"10.1016\/j.neuroscience.2017.04.047_b0065","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.cub.2013.01.009","article-title":"Vinculin regulates the recruitment and release of core focal adhesion proteins in a force-dependent manner","volume":"23","author":"Carisey","year":"2013","journal-title":"Curr. Biol."},{"key":"10.1016\/j.neuroscience.2017.04.047_b0070","doi-asserted-by":"crossref","first-page":"3105","DOI":"10.1111\/j.1582-4934.2012.01621.x","article-title":"BDNF-mediated migration of cardiac microvascular endothelial cells is impaired during ageing","volume":"16","author":"Cao","year":"2012","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0075","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1002\/jnr.22057","article-title":"Amyloid-beta interrupts the PI3K-Akt-mTOR signaling pathway that could be involved in brain-derived neurotrophic factor-induced Arc expression in rat cortical neurons","volume":"87","author":"Chen","year":"2009","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0080","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1111\/j.1460-9568.2007.05818.x","article-title":"BDNF\/TrkB interaction regulates migration of SVZ precursor cells via PI3-K and MAP-K signalling pathways","volume":"26","author":"Chiaramello","year":"2007","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0085","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1523\/JNEUROSCI.17-07-02295.1997","article-title":"Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport","volume":"17","author":"Conner","year":"1997","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0090","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1460-9568.2004.03813.x","article-title":"Doublecortin expression levels in adult brain reflect neurogenesis","volume":"21","author":"Couillard-Despres","year":"2005","journal-title":"Eur J Neurosci"},{"issue":"6","key":"10.1016\/j.neuroscience.2017.04.047_b0095","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/nprot.2015.056","article-title":"A ring barrier-based migration assay to assess cell migration in vitro","volume":"10","author":"Das","year":"2015","journal-title":"Nat Protoc"},{"issue":"4","key":"10.1016\/j.neuroscience.2017.04.047_b0100","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0896-6273(04)00266-1","article-title":"Excitation-neurogenesis coupling in adult neural stem\/progenitor cells","volume":"42","author":"Deisseroth","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0105","doi-asserted-by":"crossref","first-page":"L429","DOI":"10.1152\/ajplung.2000.279.3.L429","article-title":"Protein kinase C isozymes and the regulation of diverse cell responses","volume":"279","author":"Dempsey","year":"2000","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0110","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1002\/neu.20100","article-title":"BDNF regulates primary dendrite formation in cortical neurons via the PI3-kinase and MAP kinase signaling pathways","volume":"62","author":"Dijkhuizen","year":"2005","journal-title":"J Neurobiol"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0115","doi-asserted-by":"crossref","first-page":"10697","DOI":"10.1074\/jbc.275.14.10697","article-title":"Dual role of pseudosubstrate in the coordinated regulation of protein kinase C by phosphorylation and diacylglycerol","volume":"275","author":"Dutil","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0120","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.brainres.2007.12.003","article-title":"Neurotrophin expression in the adult olfactory epithelium","volume":"1196","author":"Feron","year":"2008","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0125","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0920-9964(99)00055-9","article-title":"Altered adhesion, proliferation and death in neural cultures from adults with schizophrenia","volume":"40","author":"Feron","year":"1999","journal-title":"Schizophr Res"},{"issue":"3","key":"10.1016\/j.neuroscience.2017.04.047_b0130","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1369\/0022155413517701","article-title":"Protein kinase C, focal adhesions and the regulation of cell migration","volume":"62","author":"Fogh","year":"2014","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijdevneu.2017.01.013","article-title":"Pharmacological inhibition of DNA methyiltransferase 1 promotes neuronal differentiation from rodent and human nasal olfactory stem\/progenitor cell cultures","author":"Franco","year":"2017","journal-title":"Int J Dev Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0140","doi-asserted-by":"crossref","first-page":"e0119711","DOI":"10.1371\/journal.pone.0119711","article-title":"BDNF-TrkB axis regulates migration of the lateral line primordium and modulates the maintenance of mechanoreceptor progenitors","volume":"10","author":"Gasanov","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0145","first-page":"185","article-title":"Horizontal basal cell proliferation in the olfactory epithelium of transforming growth factor-alpha transgenic mice","volume":"299","author":"Getchell","year":"2000","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0150","doi-asserted-by":"crossref","DOI":"10.3791\/2762","article-title":"Isolating nasal olfactory stem cells from rodents or humans","author":"Girard","year":"2011","journal-title":"J Vis Exp"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0155","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1002\/cne.903440303","article-title":"Localization and regulation of low affinity nerve growth factor receptor expression in the rat olfactory system during development and regeneration","volume":"344","author":"Gong","year":"1994","journal-title":"J Comparative Neurol"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0160","doi-asserted-by":"crossref","first-page":"3395","DOI":"10.1523\/JNEUROSCI.5352-08.2009","article-title":"Environmental enrichment restores memory functioning in mice with impaired IL-1 signaling via reinstatement of long-term potentiation and spine size enlargement","volume":"29","author":"Goshen","year":"2009","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0165","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1101\/lm.6.3.243","article-title":"Signaling mechanisms mediating BDNF modulation of synaptic plasticity in the hippocampus","volume":"6","author":"Gottschalk","year":"1999","journal-title":"Learn Mem"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0170","doi-asserted-by":"crossref","first-page":"e55039","DOI":"10.1371\/journal.pone.0055039","article-title":"Brain-derived neurotrophic factor promotes vasculature-associated migration of neuronal precursors toward the ischemic striatum","volume":"8","author":"Grade","year":"2013","journal-title":"PLoS ONE"},{"issue":"1","key":"10.1016\/j.neuroscience.2017.04.047_b0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01206454","article-title":"Neurogenesis and neuron regeneration in the olfactory system of mammals. I. Morphological aspects of differentiation and structural organization of the olfactory sensory neurons","volume":"8","author":"Graziadei","year":"1979","journal-title":"J Neurocytol"},{"issue":"8","key":"10.1016\/j.neuroscience.2017.04.047_b0180","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1002\/lary.21856","article-title":"Immunohistochemical characterization of human olfactory tissue","volume":"121","author":"Holbrook","year":"2011","journal-title":"Laryngoscope"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0185","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1006\/dbio.1995.0025","article-title":"Apoptosis in the neuronal lineage of the mouse olfactory epithelium: regulation in vivo and in vitro","volume":"172","author":"Holcomb","year":"1995","journal-title":"Dev Biol"},{"issue":"4","key":"10.1016\/j.neuroscience.2017.04.047_b0190","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/cne.23470","article-title":"Label-retaining, quiescent globose basal cells are found in the olfactory epithelium","volume":"522","author":"Jang","year":"2014","journal-title":"J Comp Neurol"},{"issue":"3","key":"10.1016\/j.neuroscience.2017.04.047_b0195","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/cne.21328","article-title":"Nonintegrin laminin receptor precursor protein is expressed on olfactory stem and progenitor cells","volume":"502","author":"Jang","year":"2007","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0200","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1183\/09031936.00051608","article-title":"Neuroendocrine cells of nasal mucosa are a cellular source of brain-derived neurotrophic factor","volume":"32","author":"Jornot","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0205","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.tins.2004.05.013","article-title":"Milestones of neuronal development in the adult hippocampus","volume":"27","author":"Kempermann","year":"2004","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0210","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.expneurol.2011.02.014","article-title":"The generation of olfactory epithelial neurospheres in vitro predicts engraftment capacity following transplantation in vivo","volume":"229","author":"Krolewski","year":"2011","journal-title":"Exp Neurol"},{"issue":"4","key":"10.1016\/j.neuroscience.2017.04.047_b0215","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1002\/cne.23204","article-title":"Global expression profiling of globose basal cells and neurogenic progression within the olfactory epithelium","volume":"521","author":"Krolewski","year":"2013","journal-title":"J Comp Neurol."},{"key":"10.1016\/j.neuroscience.2017.04.047_b0220","doi-asserted-by":"crossref","first-page":"6112","DOI":"10.1523\/JNEUROSCI.4630-12.2013","article-title":"BDNF regulates Rab11-mediated recycling endosome dynamics to induce dendritic branching","volume":"33","author":"Lazo","year":"2013","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0225","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.brainres.2006.09.058","article-title":"Catalpol increases hippocampal neuroplasticity and up-regulates PKC and BDNF in the aged rats","volume":"1123","author":"Liu","year":"2006","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0230","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1093\/brain\/awf014","article-title":"Olfactory ensheathing cells promote locomotor recovery after delayed transplantation into transected spinal cord","volume":"125","author":"Lu","year":"2002","journal-title":"Brain"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0235","first-page":"47","article-title":"Stem cells and their niche in the adult olfactory mucosa","volume":"148","author":"Mackay-Sim","year":"2010","journal-title":"Arch Ital Biol"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0240","doi-asserted-by":"crossref","first-page":"2376","DOI":"10.1093\/brain\/awn173","article-title":"Autologous olfactory ensheathing cell transplantation in human paraplegia: a 3-year clinical trial","volume":"131","author":"Mackay-Sim","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0245","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1523\/JNEUROSCI.11-04-00979.1991","article-title":"Cell dynamics in the adult mouse olfactory epithelium: a quantitative autoradiographic study","volume":"11","author":"Mackay-Sim","year":"1991","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0250","first-page":"633","article-title":"The therapeutic potential of human olfactory-derived stem cells","volume":"21","author":"Marshall","year":"2006","journal-title":"Histol Histopathol"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0255","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1242\/dmm.005447","article-title":"Disease-specific, neurosphere-derived cells as models for brain disorders","volume":"3","author":"Matigian","year":"2010","journal-title":"Dis Model Mech"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0260","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1002\/jcp.22942","article-title":"Brain-derived neurotrophic factor induces migration of endothelial cells through a TrkB-ERK-integrin alphaVbeta3-FAK cascade","volume":"227","author":"Matsuda","year":"2012","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0265","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.schres.2005.10.012","article-title":"Cell cycle alterations in biopsied olfactory neuroepithelium in schizophrenia and bipolar I disorder using cell culture and gene expression analyses","volume":"82","author":"McCurdy","year":"2006","journal-title":"Schizophr Res"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0270","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1744-8069-9-12","article-title":"BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state","volume":"9","author":"Melemedjian","year":"2013","journal-title":"Mol Pain"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0275","doi-asserted-by":"crossref","first-page":"7116","DOI":"10.1523\/JNEUROSCI.20-18-07116.2000","article-title":"Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats","volume":"20","author":"Mizuno","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0280","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/glia.21247","article-title":"Glial cells in adult neurogenesis","volume":"60","author":"Morrens","year":"2011","journal-title":"Glia"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0285","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1002\/dvdy.20360","article-title":"Multipotent stem cells from adult olfactory mucosa","volume":"233","author":"Murrell","year":"2005","journal-title":"Dev Dyn"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0290","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1634\/stemcells.2008-0074","article-title":"Olfactory mucosa is a potential source for autologous stem cell therapy for Parkinson's disease","volume":"26","author":"Murrell","year":"2008","journal-title":"Stem Cells"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0295","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/jcbfm.2014.185","article-title":"Increased BDNF protein expression after ischemic or PKC epsilon preconditioning promotes electrophysiologic changes that lead to neuroprotection","volume":"35","author":"Neumann","year":"2015","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0300","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.scr.2015.04.006","article-title":"Isolation of human adult olfactory sphere cells as a cell source of neural progenitors","volume":"15","author":"Ohnishi","year":"2015","journal-title":"Stem Cell Res"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0305","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.neuron.2006.10.019","article-title":"Odorant receptor map in the mouse olfactory bulb: in vivo sensitivity and specificity of receptor-defined glomeruli","volume":"52","author":"Oka","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0310","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s12640-016-9673-x","article-title":"Brain-derived neurotrophic factor induces cell survival and the migration of murine adult hippocampal precursor cells during differentiation in vitro","volume":"31","author":"Ortiz-Lopez","year":"2017","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.neuroscience.2017.04.047_b0315","doi-asserted-by":"crossref","first-page":"2132","DOI":"10.1093\/cercor\/bhp275","article-title":"BDNF\/MAPK\/ERK-induced BMP7 expression in the developing cerebral cortex induces premature radial glia differentiation and impairs neuronal migration","volume":"20","author":"Ortega","year":"2010","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0320","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/10520290500469777","article-title":"Clonal analysis of adult human olfactory neurosphere forming cells","volume":"80","author":"Othman","year":"2005","journal-title":"Biotech Histochem"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0325","first-page":"1057","article-title":"Williams' neural stem cells: new model for insight into microRNA dysregulation","volume":"5","author":"Palacios-Reyes","year":"2013","journal-title":"Front Biosci (Elite Ed)"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0330","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1242\/jcs.018473","article-title":"Actin stress fibres","volume":"120","author":"Pellegrin","year":"2007","journal-title":"J Cell Sci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0340","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1038\/npp.2009.46","article-title":"Melatonin modulates cell survival of new neurons in the hippocampus of adult mice","volume":"34","author":"Ramirez-Rodriguez","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0345","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.neuroscience.2013.12.026","article-title":"Environmental enrichment induces neuroplastic changes in middle age female Balb\/c mice and increases the hippocampal levels of BDNF, p-Akt and p-MAPK1\/2","volume":"260","author":"Ramirez-Rodriguez","year":"2014","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0350","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/j.1600-079X.2006.00404.x","article-title":"Melatonin increases stress fibers and focal adhesions in MDCK cells: participation of Rho-associated kinase and protein kinase C","volume":"42","author":"Ramirez-Rodriguez","year":"2007","journal-title":"J Pineal Res"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0355","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0006-8993(00)03016-X","article-title":"Adult human olfactory stem cells","volume":"890","author":"Roisen","year":"2001","journal-title":"Brain Res"},{"issue":"4","key":"10.1016\/j.neuroscience.2017.04.047_b0360","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1523\/JNEUROSCI.16-04-01294.1996","article-title":"Sequential expression of trks A, B, and C in the regenerating olfactory neuroepithelium","volume":"16","author":"Roskams","year":"1996","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0365","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1523\/JNEUROSCI.3741-04.2005","article-title":"Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus","volume":"25","author":"Sairanen","year":"2005","journal-title":"J Neurosci"},{"issue":"11","key":"10.1016\/j.neuroscience.2017.04.047_b0370","doi-asserted-by":"crossref","first-page":"3556","DOI":"10.1523\/JNEUROSCI.11-11-03556.1991","article-title":"Characterization of potential precursor populations in the mouse olfactory epithelium using immunocytochemistry and autoradiography","volume":"11","author":"Schwartz Levey","year":"1991","journal-title":"J Neurosci"},{"issue":"1","key":"10.1016\/j.neuroscience.2017.04.047_b0375","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1002\/ar.10047","article-title":"Neural regeneration and the peripheral olfactory system","volume":"269","author":"Schwob","year":"2002","journal-title":"Anat Rec"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0380","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/mp.2009.67","article-title":"Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis","volume":"15","author":"Taliaz","year":"2010","journal-title":"Mol Psychiatry"},{"issue":"4","key":"10.1016\/j.neuroscience.2017.04.047_b0385","first-page":"278","article-title":"(Immunohistological and electrophysiological characterization of Globose basal stem cells","volume":"17","author":"Thakur","year":"2014","journal-title":"Iran J Basic Med Sci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0390","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1007\/s00018-014-1564-9","article-title":"Role of p75 neurotrophin receptor in stem cell biology: more than just a marker","volume":"71","author":"Tomellini","year":"2014","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0395","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0736-5748(92)90025-U","article-title":"Regulation of the low affinity receptor for nerve growth factor, p75NGFR, in the olfactory system of neonalta and adult rat","volume":"10","author":"Turner","year":"1992","journal-title":"Int J Dev Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0400","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1111\/j.1460-9568.2004.03720.x","article-title":"Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition","volume":"20","author":"Vaynman","year":"2004","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0405","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.nbd.2007.01.012","article-title":"Human adult olfactory neural progenitors promote axotomized rubrospinal tract axonal reinnervation and locomotor recovery","volume":"26","author":"Xiao","year":"2007","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0410","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0024-3205(01)01461-8","article-title":"Role for brain-derived neurotrophic factor in learning and memory","volume":"70","author":"Yamada","year":"2002","journal-title":"Life Sci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0415","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/(SICI)1096-9861(19970203)378:1<135::AID-CNE8>3.0.CO;2-5","article-title":"Immunocytochemical localization of TrkB in the central nervous system of the adult rat","volume":"378","author":"Yan","year":"1997","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0420","doi-asserted-by":"crossref","first-page":"3583","DOI":"10.1242\/jcs.114.20.3583","article-title":"Molecular complexity and dynamics of cell-matrix adhesions","volume":"114","author":"Zamir","year":"2001","journal-title":"J Cell Sci"},{"issue":"9","key":"10.1016\/j.neuroscience.2017.04.047_b0425","doi-asserted-by":"crossref","first-page":"4605","DOI":"10.1242\/jcs.00792","article-title":"Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells","volume":"116","author":"Zaidel-Bar","year":"2003","journal-title":"J Cell Sci"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0430","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.expneurol.2003.10.022","article-title":"Adult human olfactory neural progenitors cultured in defined medium","volume":"186","author":"Zhang","year":"2004","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0435","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.cell.2008.01.033","article-title":"Mechanisms and functional implications of adult neurogenesis","volume":"132","author":"Zhao","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2017.04.047_b0440","doi-asserted-by":"crossref","first-page":"21353","DOI":"10.1073\/pnas.0812872106","article-title":"PKCdelta regulates cortical radial migration by stabilizing the Cdk5 activator p35","volume":"106","author":"Zhao","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"9","key":"10.1016\/j.neuroscience.2017.04.047_b0445","doi-asserted-by":"crossref","first-page":"7396","DOI":"10.1074\/jbc.M110008200","article-title":"A lipid-regulated docking site on vinculin for protein kinase C","volume":"277","author":"Ziegler","year":"2002","journal-title":"J Biol Chem"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452217303159?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452217303159?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T11:31:16Z","timestamp":1659007876000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452217303159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":88,"alternative-id":["S0306452217303159"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2017.04.047","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7]]}}}