{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T09:07:14Z","timestamp":1790759234976,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1016\/j.neuroscience.2017.10.008","type":"journal-article","created":{"date-parts":[[2017,10,14]],"date-time":"2017-10-14T16:17:42Z","timestamp":1507997862000},"page":"54-61","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Neural Basis of Ventromedial Hypothalamic Oxytocin-Driven Decrease in Appetite"],"prefix":"10.1016","volume":"366","author":[{"given":"Oscar A.","family":"Klockars","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph R.","family":"Waas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anica","family":"Klockars","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen S.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawel K.","family":"Olszewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.neuroscience.2017.10.008_b0005","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0196-9781(89)90082-X","article-title":"Influence of oxytocin on feeding behavior in the rat","volume":"10","author":"Arletti","year":"1989","journal-title":"Peptides"},{"issue":"5","key":"10.1016\/j.neuroscience.2017.10.008_b0010","doi-asserted-by":"crossref","first-page":"R1385","DOI":"10.1152\/ajpregu.00030.2008","article-title":"Food deprivation increases the mRNA expression of micro-opioid receptors in the ventral medial hypothalamus and arcuate nucleus","volume":"295","author":"Barnes","year":"2008","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"4\u20135","key":"10.1016\/j.neuroscience.2017.10.008_b0015","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.physbeh.2008.12.007","article-title":"Amygdalar opioids modulate hypothalamic melanocortin-induced anorexia","volume":"96","author":"Beckman","year":"2009","journal-title":"Physiol Behav"},{"issue":"1","key":"10.1016\/j.neuroscience.2017.10.008_b0020","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/cne.903480103","article-title":"Organization of projections from the ventromedial nucleus of the hypothalamus: a Phaseolus vulgaris-leucoagglutinin study in the rat","volume":"348","author":"Canteras","year":"1994","journal-title":"J Comp Neurol"},{"issue":"5","key":"10.1016\/j.neuroscience.2017.10.008_b0025","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1038\/sj.npp.1301214","article-title":"Delayed satiety-like actions and altered feeding microstructure by a selective type 2 corticotropin-releasing factor agonist in rats: intra-hypothalamic urocortin 3 administration reduces food intake by prolonging the post-meal interval","volume":"32","author":"Fekete","year":"2007","journal-title":"Neuropsychopharmacology"},{"issue":"4","key":"10.1016\/j.neuroscience.2017.10.008_b0030","doi-asserted-by":"crossref","first-page":"R876","DOI":"10.1152\/ajpregu.00655.2010","article-title":"Sucrose self-administration and CNS activation in the rat","volume":"300","author":"Figlewicz","year":"2011","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"5","key":"10.1016\/j.neuroscience.2017.10.008_b0035","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.yhbeh.2008.07.011","article-title":"Infusions of naloxone into the medial preoptic area, ventromedial nucleus of the hypothalamus, and amygdala block conditioned place preference induced by paced mating behavior","volume":"54","author":"Garcia-Horsman","year":"2008","journal-title":"Horm Behav"},{"issue":"12","key":"10.1016\/j.neuroscience.2017.10.008_b0040","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1097\/WNR.0000000000000201","article-title":"Functional relationship between oxytocin and appetite for carbohydrates versus saccharin","volume":"25","author":"Herisson","year":"2014","journal-title":"NeuroReport"},{"issue":"4","key":"10.1016\/j.neuroscience.2017.10.008_b0045","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12381","article-title":"Oxytocin acting in the nucleus accumbens core decreases food intake","volume":"28","author":"Herisson","year":"2016","journal-title":"J Neuroendocrinol"},{"issue":"8","key":"10.1016\/j.neuroscience.2017.10.008_b0050","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1210\/en.2014-1148","article-title":"Hindbrain oxytocin receptors contribute to the effects of circulating oxytocin on food intake in male rats","volume":"155","author":"Ho","year":"2014","journal-title":"Endocrinology"},{"issue":"1\u20132","key":"10.1016\/j.neuroscience.2017.10.008_b0055","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.molbrainres.2004.12.013","article-title":"Differential expression of dopamine D2 and D4 receptor and tyrosine hydroxylase mRNA in mice prone, or resistant, to chronic high-fat diet-induced obesity","volume":"135","author":"Huang","year":"2005","journal-title":"Brain Res Mol Brain Res"},{"issue":"1\u20132","key":"10.1016\/j.neuroscience.2017.10.008_b0060","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0006-8993(01)02322-8","article-title":"Identification of central sites involved in butorphanol-induced feeding in rats","volume":"907","author":"Kim","year":"2001","journal-title":"Brain Res"},{"issue":"3","key":"10.1016\/j.neuroscience.2017.10.008_b0065","doi-asserted-by":"crossref","first-page":"R1063","DOI":"10.1152\/ajpregu.00228.2007","article-title":"Oxytocin gene deletion mice overconsume palatable sucrose solution but not palatable lipid emulsions","volume":"293","author":"Miedlar","year":"2007","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.neuroscience.2017.10.008_b0070","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.brainres.2013.03.026","article-title":"Oxytocin action in the ventral tegmental area affects sucrose intake","volume":"1513","author":"Mullis","year":"2013","journal-title":"Brain Res"},{"issue":"3","key":"10.1016\/j.neuroscience.2017.10.008_b0075","doi-asserted-by":"crossref","first-page":"985","DOI":"10.3390\/nu6030985","article-title":"Intermittent feeding schedules\u2013behavioural consequences and potential clinical significance","volume":"6","author":"Murphy","year":"2014","journal-title":"Nutrients"},{"issue":"Pt A","key":"10.1016\/j.neuroscience.2017.10.008_b0080","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.physbeh.2016.05.047","article-title":"The ventromedial hypothalamus oxytocin induces locomotor behavior regulated by estrogen","volume":"164","author":"Narita","year":"2016","journal-title":"Physiol Behav"},{"issue":"2","key":"10.1016\/j.neuroscience.2017.10.008_b0085","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0006-8993(85)91586-0","article-title":"Diffusion from an injected volume of a substance in brain tissue with arbitrary volume fraction and tortuosity","volume":"333","author":"Nicholson","year":"1985","journal-title":"Brain Res"},{"issue":"8","key":"10.1016\/j.neuroscience.2017.10.008_b0090","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1046\/j.1365-2826.1999.00368.x","article-title":"Effects of central and peripheral injection of leptin on food intake and on brain Fos expression in the Otsuka Long-Evans Tokushima Fatty rat with hyperleptinaemia","volume":"11","author":"Niimi","year":"1999","journal-title":"J Neuroendocrinol"},{"issue":"6","key":"10.1016\/j.neuroscience.2017.10.008_b0095","doi-asserted-by":"crossref","first-page":"R737","DOI":"10.1152\/ajpregu.00118.2014","article-title":"Oxytocin in the ventromedial hypothalamic nucleus reduces feeding and acutely increases energy expenditure","volume":"307","author":"Noble","year":"2014","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"10","key":"10.1016\/j.neuroscience.2017.10.008_b0100","doi-asserted-by":"crossref","first-page":"4736","DOI":"10.1210\/en.2010-0151","article-title":"Molecular, immunohistochemical, and pharmacological evidence of oxytocin's role as inhibitor of carbohydrate but not fat intake","volume":"151","author":"Olszewski","year":"2010","journal-title":"Endocrinology"},{"issue":"4","key":"10.1016\/j.neuroscience.2017.10.008_b0105","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12376","article-title":"Oxytocin: a conditional anorexigen whose effects on appetite depend on the physiological, behavioural and social contexts","volume":"28","author":"Olszewski","year":"2016","journal-title":"J Neuroendocrinol"},{"issue":"14","key":"10.1016\/j.neuroscience.2017.10.008_b0110","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1097\/WNR.0000000000000647","article-title":"Central oxytocin receptor stimulation attenuates the orexigenic effects of butorphanol tartrate","volume":"27","author":"Olszewski","year":"2016","journal-title":"NeuroReport"},{"key":"10.1016\/j.neuroscience.2017.10.008_b0115","doi-asserted-by":"crossref","unstructured":"Paxinos G (1982) Plates and figures A2 \u2013 Paxinos, George. In: The rat brain in stereotaxic coordinates, (Watson C, ed), pp 13\u2013153: Academic Press.","DOI":"10.1016\/B978-0-12-547620-1.50010-2"},{"issue":"4","key":"10.1016\/j.neuroscience.2017.10.008_b0120","first-page":"285","article-title":"Sympathetic activity and food intake of rats with ventromedial hypothalamic lesions","volume":"12","author":"Sakaguchi","year":"1988","journal-title":"Int J Obes"},{"issue":"10","key":"10.1016\/j.neuroscience.2017.10.008_b0125","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1038\/nn1550","article-title":"Topographic mapping of VMH\u202f\u2192\u202farcuate nucleus microcircuits and their reorganization by fasting","volume":"8","author":"Sternson","year":"2005","journal-title":"Nat Neurosci"},{"issue":"6","key":"10.1016\/j.neuroscience.2017.10.008_b0130","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/0031-9384(89)90099-1","article-title":"Effects of food restriction and adrenalectomy in rats with VMH or PVH lesions","volume":"45","author":"Tokunaga","year":"1989","journal-title":"Physiol Behav"},{"issue":"52","key":"10.1016\/j.neuroscience.2017.10.008_b0135","doi-asserted-by":"crossref","first-page":"14265","DOI":"10.1523\/JNEUROSCI.3308-07.2007","article-title":"Selective deletion of BDNF in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity","volume":"27","author":"Unger","year":"2007","journal-title":"J Neurosci"},{"issue":"Pt A","key":"10.1016\/j.neuroscience.2017.10.008_b0140","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.neuropharm.2016.07.039","article-title":"GLP-1 and estrogen conjugate acts in the supramammillary nucleus to reduce food-reward and body weight","volume":"110","author":"Vogel","year":"2016","journal-title":"Neuropharmacology"},{"issue":"3","key":"10.1016\/j.neuroscience.2017.10.008_b0145","doi-asserted-by":"crossref","first-page":"R992","DOI":"10.1152\/ajpregu.00516.2006","article-title":"Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus increases energy expenditure by elevating metabolic rate","volume":"293","author":"Wang","year":"2007","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"4","key":"10.1016\/j.neuroscience.2017.10.008_b0150","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1016\/j.neuroimage.2010.01.065","article-title":"Peripherally injected cholecystokinin-induced neuronal activation is modified by dietary composition in mice","volume":"50","author":"Zeeni","year":"2010","journal-title":"NeuroImage"},{"issue":"5","key":"10.1016\/j.neuroscience.2017.10.008_b0155","doi-asserted-by":"crossref","first-page":"E1004","DOI":"10.1152\/ajpendo.00196.2011","article-title":"Circadian intervention of obesity development via resting-stage feeding manipulation or oxytocin treatment","volume":"301","author":"Zhang","year":"2011","journal-title":"Am J Physiol Endocrinol Metab"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452217307273?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452217307273?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T14:04:53Z","timestamp":1570197893000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452217307273"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":31,"alternative-id":["S0306452217307273"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2017.10.008","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12]]}}}