{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T21:22:35Z","timestamp":1783286555622,"version":"3.54.6"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,3,30]],"date-time":"2019-03-30T00:00:00Z","timestamp":1553904000000},"content-version":"am","delay-in-days":333,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ibroneuroscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1016\/j.neuroscience.2018.02.027","type":"journal-article","created":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T22:38:05Z","timestamp":1519684685000},"page":"126-141","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"special_numbering":"C","title":["Quantitative Analysis of Catecholamines in the Pink1 \u2212\/\u2212 Rat Model of Early-onset Parkinson\u2019s Disease"],"prefix":"10.1016","volume":"379","author":[{"given":"Cynthia A.","family":"Kelm-Nelson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6670-2177","authenticated-orcid":false,"given":"Michael A.","family":"Trevino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle R.","family":"Ciucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2018.02.027_b0005","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1126\/science.841304","article-title":"Norepinephrine-dopamine interactions and behavior","volume":"195","author":"Antelman","year":"1977","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0010","first-page":"1316","article-title":"A strategy for the generation, characterization and distribution of animal models by The Michael J. Fox Foundation for Parkinson\u2019s Research","volume":"6","author":"Baptista","year":"2013","journal-title":"Dis Model Mech"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0015","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1212\/WNL.0b013e3181c2937c","article-title":"The locus ceruleus norepinephrine system: functional organization and potential clinical significance","volume":"73","author":"Benarroch","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0020","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/0022-510X(73)90175-5","article-title":"Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations","volume":"20","author":"Bernheimer","year":"1973","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0025","doi-asserted-by":"crossref","first-page":"10999","DOI":"10.1523\/JNEUROSCI.23-35-10999.2003","article-title":"Enriched environment confers resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and cocaine: involvement of dopamine transporter and trophic factors","volume":"23","author":"Bezard","year":"2003","journal-title":"J Neurosci"},{"issue":"Supplement 1","key":"10.1016\/j.neuroscience.2018.02.027_b0030","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1016\/S1353-8020(11)70004-9","article-title":"Autosomal recessive parkinsonism","volume":"18","author":"Bonifati","year":"2012","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0035","doi-asserted-by":"crossref","first-page":"s59","DOI":"10.1007\/s100720200069","article-title":"Autosomal recessive early onset parkinsonism is linked to three loci: PARK2, PARK6, and PARK7","volume":"23","author":"Bonifati","year":"2002","journal-title":"Neurol Sci"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0040","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s00441-004-0956-9","article-title":"Stages in the development of Parkinson\u2019s disease-related pathology","volume":"318","author":"Braak","year":"2004","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0045","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0197-4580(02)00065-9","article-title":"Staging of brain pathology related to sporadic Parkinson\u2019s disease","volume":"24","author":"Braak","year":"2003","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0050","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1023\/A:1018970617104","article-title":"Pharmacokinetics of levodopa and carbidopa in rats following different routes of administration","volume":"11","author":"Bredberg","year":"1994","journal-title":"Pharm Res"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0055","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1037\/0735-7036.116.1.73","article-title":"Social contacts and production of 50-kHz short ultrasonic calls in adult rats","volume":"116","author":"Brudzynski","year":"2002","journal-title":"J Comp Psychol"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0060","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/mds.870120211","article-title":"Step initiation in Parkinson's disease: Influence of levodopa and external sensory triggers","volume":"12","author":"Burleigh-Jacobs","year":"1997","journal-title":"Mov Disord"},{"key":"10.1016\/j.neuroscience.2018.02.027_b9000","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1373\/clinchem.2008.112797","article-title":"The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments","volume":"55","author":"Bustin","year":"2009","journal-title":"Clin Chem"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0065","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/nrn877","article-title":"Animal models of neurological deficits: how relevant is the rat?","volume":"3","author":"Cenci","year":"2002","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0070","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1037\/a0014593","article-title":"Reduction of dopamine synaptic activity: degradation of 50-khz ultrasonic vocalization in rats","volume":"123","author":"Ciucci","year":"2009","journal-title":"Behav Neurosci"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0075","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.bbr.2007.02.020","article-title":"Qualitative changes in ultrasonic vocalization in rats after unilateral dopamine depletion or haloperidol: a preliminary study","volume":"182","author":"Ciucci","year":"2007","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0080","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1037\/0033-2909.112.1.155","article-title":"A power primer","volume":"112","author":"Cohen","year":"1992","journal-title":"Psychol Bull"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0085","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.jvoice.2006.10.010","article-title":"Effects of bilateral subthalamic nucleus stimulation and medication on parkinsonian speech impairment","volume":"22","author":"D'Alatri","year":"2008","journal-title":"J Voice"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0090","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.nbd.2014.06.009","article-title":"Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease","volume":"70","author":"Dave","year":"2014","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0095","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1212\/01.WNL.0000140706.52798.BE","article-title":"Incidence of parkinsonism and Parkinson disease in a general population: the Rotterdam Study","volume":"63","author":"de Lau","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0100","first-page":"19","article-title":"Levodopa-induced alterations in speech rate in advanced Parkinson's disease","volume":"106","author":"De Letter","year":"2006","journal-title":"Acta Neurol Belg"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0105","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3389\/fnsys.2011.00031","article-title":"Noradrenaline and Parkinson's disease","volume":"5","author":"Delaville","year":"2011","journal-title":"Front Syst Neurosci"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0110","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1002\/1531-8257(200011)15:6<1132::AID-MDS1011>3.0.CO;2-O","article-title":"An investigation of the effects of subthalamic nucleus stimulation on acoustic measures of voice","volume":"15","author":"Dromey","year":"2000","journal-title":"Mov Disord"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0115","doi-asserted-by":"crossref","first-page":"9434","DOI":"10.1523\/JNEUROSCI.3080-04.2004","article-title":"Early and progressive sensorimotor anomalies in mice overexpressing wild-type human \u03b1-synuclein","volume":"24","author":"Fleming","year":"2004","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0120","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.expneurol.2004.01.023","article-title":"Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone","volume":"187","author":"Fleming","year":"2004","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0125","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1055\/s-2006-955118","article-title":"The science and practice of LSVT\/LOUD: neural plasticity-principled approach to treating individuals with Parkinson disease and other neurological disorders","volume":"27","author":"Fox","year":"2006","journal-title":"Semin Speech Lang"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0130","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1002\/jnr.23625","article-title":"Evidence for early and progressive ultrasonic vocalization and oromotor deficits in a PINK1 knockout rat model of Parkinson disease","volume":"93","author":"Grant","year":"2015","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0135","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s10072-010-0360-z","article-title":"Clinical features and 11C-CFT PET analysis of PARK2, PARK6, PARK7-linked autosomal recessive early onset Parkinsonism","volume":"32","author":"Guo","year":"2011","journal-title":"Neurol Sci"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0140","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1080\/00207450390249258","article-title":"Population-level right paw preference in rats assessed by a new computerized forod-reaching test","volume":"113","author":"G\u00fcven","year":"2003","journal-title":"Int J Neurosci"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0145","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.bandc.2004.05.002","article-title":"Variability in fundamental frequency during speech in prodromal and incipient Parkinson's disease: a longitudinal case study","volume":"56","author":"Harel","year":"2004","journal-title":"Brain Cogn"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0150","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.jneuroling.2004.06.001","article-title":"Acoustic characteristics of Parkinsonian speech: a potential biomarker of early disease progression and treatment","volume":"17","author":"Harel","year":"2004","journal-title":"J Neurolinguist"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0155","doi-asserted-by":"crossref","DOI":"10.3791\/2835","article-title":"Targeted training of ultrasonic vocalizations in aged and Parkinsonian rats","author":"Johnson","year":"2011","journal-title":"JOVE"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0160","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/BF01244343","article-title":"Striatal membrane-bound and soluble catechol-O-methyl-transferase after selective neuronal lesions in the rat","volume":"69","author":"Kaakkola","year":"1987","journal-title":"J Neural Transm"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0165","article-title":"Characterization of early-onset motor deficits in the Pink1 -\/- mouse model of Parkinson disease","author":"Kelm-Nelson","year":"2017","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0170","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.bbr.2016.03.006","article-title":"Vocal training, levodopa, and environment effects on ultrasonic vocalizations in a rat neurotoxin model of Parkinson disease","volume":"307","author":"Kelm-Nelson","year":"2016","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0175","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.neulet.2016.04.003","article-title":"Atp13a2 expression in the periaqueductal gray is decreased in the Pink1 -\/- rat model of Parkinson disease","volume":"621","author":"Kelm-Nelson","year":"2016","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0180","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.dib.2016.05.056","article-title":"Data in support of qPCR primer design and verification in a Pink1 \u2212\/\u2212 rat model of Parkinson disease","volume":"8","author":"Kelm-Nelson","year":"2016","journal-title":"Data Brief"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0185","doi-asserted-by":"crossref","first-page":"749","DOI":"10.3233\/JPD-150688","article-title":"Exercise effects on early vocal ultrasonic communication dysfunction in a PINK1 knockout model of Parkinson's disease","volume":"5","author":"Kelm-Nelson","year":"2015","journal-title":"J Parkinsons Dis"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0190","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1111\/j.1476-5381.1990.tb14085.x","article-title":"The effect of benserazide on the peripheral and central distribution and metabolism of levodopa after acute and chronic administration in the rat","volume":"100","author":"Kent","year":"1990","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0195","doi-asserted-by":"crossref","first-page":"11441","DOI":"10.1073\/pnas.0702717104","article-title":"Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice","volume":"104","author":"Kitada","year":"2007","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0200","series-title":"Noradrenergic mechanisms in Parkinson's disease","author":"Marien","year":"1994"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0205","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.brainresrev.2004.02.002","article-title":"Noradrenergic mechanisms in neurodegenerative diseases: a theory","volume":"45","author":"Marien","year":"2004","journal-title":"Brain Res Brain Res Rev"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0210","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0306-4522(02)00556-0","article-title":"Catechol O-methyltransferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function","volume":"116","author":"Matsumoto","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0215","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0031-9384(03)00227-0","article-title":"Characterization of 50-kHz ultrasonic vocalizations in male and female rats","volume":"80","author":"McGinnis","year":"2003","journal-title":"Physiol Behav"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0220","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1002\/mds.870130607","article-title":"Gait analysis in patients with Parkinson's disease and motor fluctuations: influence of levodopa and comparison with other measures of motor function","volume":"13","author":"O'Sullivan","year":"1998","journal-title":"Mov Disord"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0225","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"2005"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0230","first-page":"131","article-title":"Perceptual characteristics of Parkinsonian speech: a comparison of the pharmacological effects of levodopa across speech and non-speech motor systems","volume":"24","author":"Plowman-Prine","year":"2009","journal-title":"NeuroRehabilitation"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0235","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.bbr.2013.06.006","article-title":"Dopamine D1 and D2 receptor antagonism effects on rat ultrasonic vocalizations","volume":"252","author":"Ringel","year":"2013","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0240","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0006-8993(88)91560-0","article-title":"Normalization of extracellular dopamine in striatum following recovery from a partial unilateral 6-OHDA lesion of the substantia nigra: a microdialysis study in freely moving rats","volume":"450","author":"Robinson","year":"1988","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0245","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.bcp.2007.01.036","article-title":"Norepinephrine: the redheaded stepchild of Parkinson's disease","volume":"74","author":"Rommelfanger","year":"2007","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0250","series-title":"The handbook of research synthesis","article-title":"Parametric measures of effect size","author":"Rosenthal","year":"1994"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0255","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s00702-012-0853-4","article-title":"Evaluation of speech impairment in early stages of Parkinson\u2019s disease: a prospective study with the role of pharmacotherapy","volume":"120","author":"Rusz","year":"2013","journal-title":"J Neural Transm"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0260","doi-asserted-by":"crossref","first-page":"295","DOI":"10.3389\/fnins.2017.00295","article-title":"Dopamine and the brainstem locomotor networks: from lamprey to human","volume":"11","author":"Ryczko","year":"2017","journal-title":"Front Neurosci"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0265","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1044\/1092-4388(2007\/064)","article-title":"Effects of intensive voice treatment (The Lee Silverman Voice Treatment [LSVT]) on vowel articulation in dysarthric individuals with idiopathic Parkinson disease: acoustic and perceptual findings","volume":"50","author":"Sapir","year":"2007","journal-title":"J Speech Lang Hear Res"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0270","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1046\/j.1468-1331.2003.00611.x","article-title":"Characterization of freezing of gait subtypes and the response of each to levodopa in Parkinson's disease","volume":"10","author":"Schaafsma","year":"2003","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0275","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0022-510X(03)00104-7","article-title":"Gait dynamics in Parkinson's disease: relationship to Parkinsonian features, falls and response to levodopa","volume":"212","author":"Schaafsma","year":"2003","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0280","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1126\/science.564552","article-title":"Compulsive, abnormal walking caused by anticholinergics in akinetic, 6-hydroxydopamine-treated rats","volume":"199","author":"Schallert","year":"1978","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0285","doi-asserted-by":"crossref","first-page":"e61392","DOI":"10.1371\/journal.pone.0061392","article-title":"Catechol-O-methyltransferase (COMT) protein expression and activity after dopaminergic and noradrenergic lesions of the rat brain","volume":"8","author":"Schendzielorz","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0290","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0021-9924(99)00025-8","article-title":"Effects of speech therapy and pharmacologic and surgical treatments on voice and speech in Parkinson's disease: a review of the literature","volume":"33","author":"Schulz","year":"2000","journal-title":"J Commun Disord"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0295","doi-asserted-by":"crossref","first-page":"2586","DOI":"10.1046\/j.1460-9568.2003.02684.x","article-title":"Potentiation of parkinsonian symptoms by depletion of locus coeruleus noradrenaline in 6-hydroxydopamine-induced partial degeneration of substantia nigra in rats","volume":"17","author":"Srinivasan","year":"2003","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0300","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1002\/mds.870100506","article-title":"Speech dysfunction in early Parkinson's disease","volume":"10","author":"Stewart","year":"1995","journal-title":"Mov Disord"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0305","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1002\/mds.23290","article-title":"The prevalence and patterns of pharyngoesophageal dysmotility in patients with early stage Parkinson's disease","volume":"25","author":"Sung","year":"2010","journal-title":"Mov Disord"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0310","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/BF02260912","article-title":"The effects of L-threo-3,4-dihydroxyphenylserine on the total norepinephrine and dopamine concentrations in the cerebrospinal fluid and freezing gait in parkinsonian patients","volume":"5","author":"Tohgi","year":"1993","journal-title":"J Neural Transm Park Dis Dement Sect"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0315","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.neuint.2016.11.009","article-title":"Targeting the norepinephrinergic system in Parkinson's disease and related disorders: the locus coeruleus story","volume":"102","author":"Vermeiren","year":"2017","journal-title":"Neurochem Int"},{"key":"10.1016\/j.neuroscience.2018.02.027_b0320","first-page":"471","article-title":"Handedness in rats","volume":"38","author":"Yoshioka","year":"1930","journal-title":"Pedagog Sem J Genetic Psychol"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452218301453?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452218301453?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T15:44:34Z","timestamp":1759679074000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452218301453"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":65,"alternative-id":["S0306452218301453"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2018.02.027","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quantitative Analysis of Catecholamines in the Pink1 \u2212\/\u2212 Rat Model of Early-onset Parkinson\u2019s Disease","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2018.02.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Ltd on behalf of IBRO.","name":"copyright","label":"Copyright"}]}}