{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T02:19:08Z","timestamp":1781835548570,"version":"3.54.5"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T00:00:00Z","timestamp":1555372800000},"content-version":"am","delay-in-days":350,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ibroneuroscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1016\/j.neuroscience.2018.03.041","type":"journal-article","created":{"date-parts":[[2018,4,4]],"date-time":"2018-04-04T10:04:26Z","timestamp":1522836266000},"page":"428-434","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Blast Exposure Disrupts the Tonotopic Frequency Map in the Primary Auditory Cortex"],"prefix":"10.1016","volume":"379","author":[{"given":"Samer","family":"Masri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li S.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Pace","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinsheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaowen","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2018.03.041_b0005","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.freeradbiomed.2013.02.029","article-title":"Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast","volume":"60","author":"Abdul-Muneer","year":"2013","journal-title":"Free Radical Biol Med"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0010","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0300-483X(97)03659-7","article-title":"Management of primary blast injury","volume":"121","author":"Argyros","year":"1997","journal-title":"Toxicology"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0015","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1089\/neu.2012.2834","article-title":"Acute mitochondrial dysfunction after blast exposure: potential role of mitochondrial glutamate oxaloacetate transaminase","volume":"30","author":"Arun","year":"2013","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0020","doi-asserted-by":"crossref","first-page":"2564","DOI":"10.1002\/jnr.21699","article-title":"Tinnitus and inferior colliculus activity in chinchillas related to three distinct patterns of cochlear trauma","volume":"86","author":"Bauer","year":"2008","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0025","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1126\/science.1067859","article-title":"Control of synaptic strength by glial TNFalpha","volume":"295","author":"Beattie","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S1355617708090036","article-title":"Cognitive sequelae of blast-related versus other mechanisms of brain trauma","volume":"15","author":"Belanger","year":"2009","journal-title":"J Int Neuropsychol Soc"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0035","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1038\/sj.jcbfm.9600487","article-title":"TNF alpha and Fas mediate tissue damage and functional outcome after traumatic brain injury in mice","volume":"27","author":"Bermpohl","year":"2007","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0040","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.heares.2016.10.018","article-title":"Sensory coding and cognitive processing of sound in Veterans with blast exposure","volume":"349","author":"Bressler","year":"2017","journal-title":"Hear Res"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0045","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1097\/00005373-200104000-00017","article-title":"Ultrastructural and functional characteristics of blast injury-induced neurotrauma","volume":"50","author":"Cernak","year":"2001","journal-title":"J Trauma Acute Care Surg"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0050","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.nbd.2010.10.025","article-title":"The pathobiology of blast injuries and blast-induced neurotrauma as identified using a new experimental model of injury in mice","volume":"41","author":"Cernak","year":"2011","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0055","first-page":"375","article-title":"Relationship between changes in the cochlear blood flow and disorder of hearing function induced by blast injury in guinea pigs","volume":"6","author":"Chen","year":"2013","journal-title":"Int J Clin Exp Path"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0060","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.freeradbiomed.2017.04.343","article-title":"Antioxidants reduce neurodegeneration and accumulation of pathologic Tau proteins in the auditory system after blast exposure","volume":"108","author":"Du","year":"2017","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0065","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/03655230600895259","article-title":"Cortical tonotopic map reorganization and its implications for treatment of tinnitus","author":"Eggermont","year":"2006","journal-title":"Acta Otolaryngol Suppl"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0070","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.heares.2007.01.008","article-title":"Correlated neural activity as the driving force for functional changes in auditory cortex","volume":"229","author":"Eggermont","year":"2007","journal-title":"Hear Res"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0075","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.tins.2004.08.010","article-title":"The neuroscience of tinnitus","volume":"27","author":"Eggermont","year":"2004","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0300-483X(97)03651-2","article-title":"Toxicology of blast overpressure","volume":"121","author":"Elsayed","year":"1997","journal-title":"Toxicology"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0085","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/nature09656","article-title":"Reversing pathological neural activity using targeted plasticity","volume":"470","author":"Engineer","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0090","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1097\/00005537-200305000-00010","article-title":"Chronic tinnitus resulting from head or neck injuries","volume":"113","author":"Folmer","year":"2003","journal-title":"Laryngoscope"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0095","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1080\/00028896409342582","article-title":"Permanent threshold shift changes produced by noise exposure and aging","volume":"25","author":"Gallo","year":"1964","journal-title":"Am Ind Hyg Assoc J"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0100","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s11481-006-9015-5","article-title":"Microglia biology in health and disease","volume":"1","author":"Garden","year":"2006","journal-title":"J Neuroimmune Pharmacol"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0105","doi-asserted-by":"crossref","first-page":"9159","DOI":"10.1523\/JNEUROSCI.0065-12.2012","article-title":"Robustness of cortical topography across fields, laminae, anesthetic states, and neurophysiological signal types","volume":"32","author":"Guo","year":"2012","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0110","first-page":"286","article-title":"Auditory and vestibular sequelae to traumatic brain injury: a pilot study","volume":"114","author":"Jury","year":"2001","journal-title":"N Z Med J"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0115","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1089\/neu.2011.1983","article-title":"Factors affecting blast traumatic brain injury","volume":"28","author":"Kamnaksh","year":"2011","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0120","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1365-2990.1995.tb01073.x","article-title":"The response of neurons and microglia to blast injury in the rat brain","volume":"21","author":"Kaur","year":"1995","journal-title":"Neuropathol Appl Neurobiol"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0125","doi-asserted-by":"crossref","first-page":"5163","DOI":"10.1523\/JNEUROSCI.0365-09.2009","article-title":"Selective increase in representations of sounds repeated at an ethological rate","volume":"29","author":"Kim","year":"2009","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0130","doi-asserted-by":"crossref","first-page":"3908","DOI":"10.1523\/JNEUROSCI.5169-04.2005","article-title":"Hearing loss raises excitability in the auditory cortex","volume":"25","author":"Kotak","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0135","first-page":"155","article-title":"Blast related neurotrauma: a review of cellular injury","volume":"5","author":"Leung","year":"2008","journal-title":"Mol Cell Biomech"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0140","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1682\/JRRD.2007.09.0140","article-title":"Auditory dysfunction in traumatic brain injury","volume":"44","author":"Lew","year":"2007","journal-title":"J Rehabil Res Dev"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0145","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.neuroscience.2016.11.014","article-title":"Blast-induced tinnitus and hyperactivity in the auditory cortex of rats","volume":"340","author":"Luo","year":"2017","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0150","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.neulet.2014.07.041","article-title":"Blast-induced tinnitus and spontaneous activity changes in the rat inferior colliculus","volume":"580","author":"Luo","year":"2014","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0155","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1002\/jnr.23424","article-title":"Blast-induced tinnitus and spontaneous firing changes in the rat dorsal cochlear nucleus","volume":"92","author":"Luo","year":"2014","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0160","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1089\/neu.2011.1934","article-title":"Blast-induced tinnitus and hearing loss in rats: behavioral and imaging assays","volume":"29","author":"Mao","year":"2012","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0165","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1177\/014556130408300713","article-title":"The relationship of tinnitus, hyperacusis, and hearing loss","volume":"83","author":"Nelson","year":"2004","journal-title":"Ear Nose Throat J"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0170","doi-asserted-by":"crossref","first-page":"31754","DOI":"10.1038\/srep31754","article-title":"Pathophysiology of the inner ear after blast injury caused by laser-induced shock wave","volume":"6","author":"Niwa","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0175","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1055\/s-0040-1715975","article-title":"Prevalence and 5-year incidence of tinnitus among older adults: the epidemiology of hearing loss study","volume":"13","author":"Nondahl","year":"2002","journal-title":"J Am Acad Audiol"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0180","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1152\/jn.00139.2003","article-title":"Neural changes in cat auditory cortex after a transient pure-tone trauma","volume":"90","author":"Norena","year":"2003","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0185","doi-asserted-by":"crossref","first-page":"4852","DOI":"10.1038\/s41598-017-04941-w","article-title":"Blast-induced tinnitus and elevated central auditory and limbic activity in rats: a manganese-enhanced MRI and behavioral study","volume":"7","author":"Ouyang","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0190","first-page":"02016","article-title":"Differences in post-injury auditory system pathophysiology after mild blast and non-blast acute acoustic trauma","volume":"00710","author":"Race","year":"2017","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0195","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1097\/MAO.0000000000000616","article-title":"Otologic outcomes after blast injury: the Boston Marathon experience","volume":"35","author":"Remenschneider","year":"2014","journal-title":"Otol Neurotol"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0200","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.injury.2009.11.018","article-title":"Bomb blast, mild traumatic brain injury and psychiatric morbidity: a review","volume":"41","author":"Rosenfeld","year":"2010","journal-title":"Injury"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0205","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1044\/1092-4388(2006\/012)","article-title":"Tinnitus and its effect on working memory and attention","volume":"49","author":"Rossiter","year":"2006","journal-title":"J Speech Language Hearing Res"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0210","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1002\/nbm.2805","article-title":"Blast-induced neurotrauma leads to neurochemical changes and neuronal degeneration in the rat hippocampus","volume":"25","author":"Sajja","year":"2012","journal-title":"NMR Biomed"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0215","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1089\/089771503767870014","article-title":"Impulse noise transiently increased the permeability of nerve and glial cell membranes, an effect accentuated by a recent brain injury","volume":"20","author":"Saljo","year":"2003","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0220","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0928-4680(01)00067-0","article-title":"Exposure to short-lasting impulse noise causes microglial and astroglial cell activation in the adult rat brain","volume":"8","author":"Saljo","year":"2001","journal-title":"Pathophysiology"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0225","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1682\/JRRD.2014.11.0275","article-title":"Auditory difficulties in blast-exposed Veterans with clinically normal hearing","volume":"52","author":"Saunders","year":"2015","journal-title":"J Rehabil Res Dev"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0230","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.apmr.2007.05.025","article-title":"Characteristics and rehabilitation outcomes among patients with blast and other injuries sustained during the Global War on Terror","volume":"89","author":"Sayer","year":"2008","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0235","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0378-5955(03)00074-1","article-title":"Changes in spontaneous firing rate and neural synchrony in cat primary auditory cortex after localized tone-induced hearing loss","volume":"180","author":"Seki","year":"2003","journal-title":"Hear Res"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0240","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1038\/nature04671","article-title":"Synaptic scaling mediated by glial TNF-alpha","volume":"440","author":"Stellwagen","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0245","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0300-483X(97)03658-5","article-title":"Biological response to blast overpressure: a summary of modeling","volume":"121","author":"Stuhmiller","year":"1997","journal-title":"Toxicology"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0250","first-page":"795","article-title":"Morphologic and biochemical characterization of brain injury in a model of controlled blast overpressure exposure","volume":"69","author":"Svetlov","year":"2010","journal-title":"J Trauma"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0255","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0378-5955(99)00175-6","article-title":"Threshold shifts and enhancement of cortical evoked responses after noise exposure in rats","volume":"139","author":"Syka","year":"2000","journal-title":"Hear Res"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0260","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/s11682-013-9257-9","article-title":"Preliminary findings of cortical thickness abnormalities in blast injured service members and their relationship to clinical findings","volume":"8","author":"Tate","year":"2014","journal-title":"Brain Imaging Behav"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0265","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1682\/JRRD.2011.09.0182","article-title":"Preliminary studies on differential expression of auditory functional genes in the brain after repeated blast exposures","volume":"49","author":"Valiyaveettil","year":"2012","journal-title":"J Rehabil Res Dev"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0270","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1001\/archotol.1994.01880290057010","article-title":"Characteristics of tinnitus induced by head injury","volume":"120","author":"Vernon","year":"1994","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0275","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1056\/NEJMc076071","article-title":"Tympanic-membrane perforation as a marker of concussive brain injury in Iraq","volume":"357","author":"Xydakis","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0280","doi-asserted-by":"crossref","first-page":"14974","DOI":"10.1073\/pnas.1107998108","article-title":"Homeostatic plasticity drives tinnitus perception in an animal model","volume":"108","author":"Yang","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2018.03.041_b0285","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1093\/cercor\/bht053","article-title":"Impaired development and competitive refinement of the cortical frequency map in tumor necrosis factor-alpha-deficient mice","volume":"24","author":"Yang","year":"2014","journal-title":"Cereb Cortex"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452218302392?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452218302392?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T15:44:53Z","timestamp":1759679093000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452218302392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":57,"alternative-id":["S0306452218302392"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2018.03.041","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Blast Exposure Disrupts the Tonotopic Frequency Map in the Primary Auditory Cortex","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2018.03.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 IBRO. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}