{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T03:31:56Z","timestamp":1785727916846,"version":"3.56.0"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T00:00:00Z","timestamp":1562716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["PO 681\/5-2"],"award-info":[{"award-number":["PO 681\/5-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["PO 681\/8-1"],"award-info":[{"award-number":["PO 681\/8-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ibroneuroscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.neuroscience.2019.06.031","type":"journal-article","created":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T19:22:26Z","timestamp":1563218546000},"page":"44-58","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Epileptogenesis-Associated Alterations of Heat Shock Protein 70 in a Rat Post-Status Epilepticus Model"],"prefix":"10.1016","volume":"415","author":[{"given":"Fabio","family":"Gualtieri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Nowakowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva-Lotta","family":"von R\u00fcden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Seiffert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidrun","family":"Potschka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2019.06.031_bb0005","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1002\/cyto.a.20896","article-title":"Quantifying colocalization by correlation: the Pearson correlation coefficient is superior to the Mander's overlap coefficient","volume":"77","author":"Adler","year":"2010","journal-title":"Cytometry A"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0015","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s00210-007-0143-0","article-title":"Pentylenetetrazol-kindling in mice overexpressing heat shock protein 70","volume":"375","author":"Ammon-Treiber","year":"2007","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0020","doi-asserted-by":"crossref","first-page":"7184","DOI":"10.4049\/jimmunol.177.10.7184","article-title":"Extracellular heat shock protein-70 induces endotoxin tolerance in THP-1 cells","volume":"177","author":"Aneja","year":"2006","journal-title":"J Immunol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0025","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/74697","article-title":"HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine","volume":"6","author":"Asea","year":"2000","journal-title":"Nat Med"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0030","first-page":"15028","article-title":"Novel signal transduction pathway utilized by extracellular HSP70","volume":"277","author":"Asea","year":"2002","journal-title":"role of Toll-like receptor (TLR) 2 and TLR4 J Biol Chem"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0035","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1016\/j.neuropharm.2008.08.035","article-title":"HSP70 expression protects against hippocampal neurodegeneration induced by endogenous glutamate in vivo","volume":"55","author":"Ayala","year":"2008","journal-title":"Neuropharmacology."},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0040","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1038\/35019501","article-title":"Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome","volume":"2","author":"Beere","year":"2000","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0045","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1212\/WNL.0b013e31820c3119","article-title":"Heat shock proteins multiple neuroprotective functions and implications for neurologic disease","volume":"76","author":"Benarroch","year":"2011","journal-title":"Neurology."},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0050","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0920-1211(03)00114-1","article-title":"Epileptogenesis and neuropathology after different types of status epilepticus induced by prolonged electrical stimulation of the basolateral amygdala in rats","volume":"55","author":"Brandt","year":"2003","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0055","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1002\/prca.200800043","article-title":"Proteomic identification of proteins in the human brain: towards a more comprehensive understanding of neurodegenerative disease","volume":"2","author":"Caudle","year":"2008","journal-title":"Proteomics Clin Appl"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0060","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.nbd.2013.10.012","article-title":"Heat shock protein 70 protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus via inhibition of nuclear factor-\u03baB activation-induced nitric oxide synthase II expression","volume":"62","author":"Chang","year":"2014","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0065","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1379\/CSC-236R.1","article-title":"Neuronal expression of constitutive heat shock proteins: implications for neurodegenerative diseases","volume":"12","author":"Chen","year":"2007","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainresbull.2012.09.014","article-title":"Activations of GABAergic signaling, HSP70 and MAPK cascades are involved in baicalin's neuroprotection against gerbil global ischemia\/reperfusion injury","volume":"90","author":"Dai","year":"2013","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0075","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.nbd.2018.06.010","article-title":"Imaging correlates of behavioral impairments: an experimental PET study in the rat pilocarpine epilepsy model","volume":"118","author":"Di Liberto","year":"2018","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0080","unstructured":"Disorders NIoN, Communications SOo, Liaison P (2015) the epilepsies and seizures: Hope through research. Department of Health & human services, NIH, National Institute of Health."},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0085","doi-asserted-by":"crossref","first-page":"C723","DOI":"10.1152\/ajpcell.00462.2010","article-title":"A practical guide to evaluating colocalization in biological microscopy","volume":"300","author":"Dunn","year":"2011","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0090","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1111\/j.1471-4159.2010.06989.x","article-title":"Exogenous protein Hsp70\/Hsc70 can penetrate into brain structures and attenuate the severity of chemically-induced seizures","volume":"115","author":"Ekimova","year":"2010","journal-title":"J Neurochem"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0095","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/1476-9255-11-19","article-title":"Heat shock protein 70 down-regulates the production of toll-like receptor-induced pro-inflammatory cytokines by a heat shock factor-1\/constitutive heat shock element-binding factor-dependent mechanism","volume":"11","author":"Ferat-Osorio","year":"2014","journal-title":"J Inflamm (Lond)"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0100","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.yebeh.2010.11.024","article-title":"Study of spontaneous recurrent seizures and morphological alterations after status epilepticus induced by intrahippocampal injection of pilocarpine","volume":"20","author":"Furtado","year":"2011","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0105","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1365-2818.1986.tb02764.x","article-title":"Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R Thompson","volume":"143","author":"Gundersen","year":"1986","journal-title":"J Microsc"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0110","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1365-2818.1987.tb02837.x","article-title":"The efficiency of systematic sampling in stereology and its prediction","volume":"147","author":"Gundersen","year":"1987","journal-title":"J Microsc"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0115","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1046\/j.1365-2818.1999.00457.x","article-title":"The efficiency of systematic sampling in stereology\u2014reconsidered","volume":"193","author":"Gundersen","year":"1999","journal-title":"J Microsc"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0120","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.celrep.2018.12.032","article-title":"Inhibition of Hsp70 suppresses neuronal Hyperexcitability and attenuates epilepsy by enhancing A-type potassium current","volume":"26","author":"Hu","year":"2019","journal-title":"Cell Rep"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0125","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s12192-008-0068-7","article-title":"Guidelines for the nomenclature of the human heat shock proteins","volume":"14","author":"Kampinga","year":"2009","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0130","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1111\/epi.12787","article-title":"Hippocampal expression of heat shock proteins in mesial temporal lobe epilepsy with psychiatric comorbidities and their relation to seizure outcome","volume":"55","author":"Kandratavicius","year":"2014","journal-title":"Epilepsia."},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0135","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.nbd.2017.05.017","article-title":"A systems level analysis of epileptogenesis-associated proteome alterations","volume":"105","author":"Keck","year":"2017","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0140","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.nbd.2018.01.013","article-title":"Proteomic profiling of epileptogenesis in a rat model: focus on cell stress, extracellular matrix and angiogenesis","volume":"112","author":"Keck","year":"2018","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5115\/acb.2013.46.1.1","article-title":"The immune modulating properties of the heat shock proteins after brain injury","volume":"46","author":"Kim","year":"2013","journal-title":"Anat Cell Biol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0150","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1080\/14728222.2018.1439477","article-title":"The 70-kDa heat shock protein (Hsp70) as a therapeutic target for stroke","volume":"22","author":"Kim","year":"2018","journal-title":"Expert Opin Ther Targets"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0155","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1039\/C4AN02153C","article-title":"Colocalization of fluorescence and Raman microscopic images for the identification of subcellular compartments: a validation study","volume":"140","author":"Krau\u00df","year":"2015","journal-title":"Analyst."},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0160","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1189\/jlb.1208763","article-title":"TLR4\/MyD88\/PI3K interactions regulate TLR4 signaling","volume":"85","author":"Laird","year":"2009","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0165","doi-asserted-by":"crossref","first-page":"4070","DOI":"10.1523\/JNEUROSCI.0346-04.2004","article-title":"A syntaxin 1, G\u03b1o, and N-type calcium channel complex at a presynaptic nerve terminal: analysis by quantitative immunocolocalization","volume":"24","author":"Li","year":"2004","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0170","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.brainres.2010.10.055","article-title":"Induction of heat shock proteins in the adult rat cerebral cortex following pilocarpine-induced status epilepticus","volume":"1368","author":"Lively","year":"2011","journal-title":"Brain Res"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0175","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0306-4522(94)00614-B","article-title":"Susceptibility of different cell layers of the anterior and posterior part of the piriform cortex to electrical stimulation and kindling: comparison with the basolateral amygdala and \"area tempestas\"","volume":"66","author":"Loscher","year":"1995","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0180","doi-asserted-by":"crossref","first-page":"31","DOI":"10.5698\/1535-7597-16.1.31","article-title":"Epileptogenesis: more than just the latent period","volume":"16","author":"Maguire","year":"2016","journal-title":"Epilepsy Curr"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0185","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/nm.2127","article-title":"Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures","volume":"16","author":"Maroso","year":"2010","journal-title":"Nat Med"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0190","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/nrn2533","article-title":"Pathological and protective roles of glia in chronic pain","volume":"10","author":"Milligan","year":"2009","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0195","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ejphar.2011.12.004","article-title":"Hsp70 promotes synaptic transmission in brain slices damaged by contact with blood clot","volume":"677","author":"Mokrushin","year":"2012","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0200","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.eplepsyres.2017.05.010","article-title":"Features of amygdala in patients with mesial temporal lobe epilepsy and hippocampal sclerosis: an MRI volumetric and histopathological study","volume":"135","author":"Nakayama","year":"2017","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0205","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.ejphar.2014.06.061","article-title":"Targeting of microglial KCa3.1 channels by TRAM-34 exacerbates hippocampal neurodegeneration and does not affect ictogenesis and epileptogenesis in chronic temporal lobe epilepsy models","volume":"740","author":"Ongerth","year":"2014","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0210","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0079-6123(06)62020-7","article-title":"Cerebral neurons and glial cell types inducing heat shock protein Hsp70 following heat stress in the rat","volume":"162","author":"Pavlik","year":"2007","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0215","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"1998"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0220","doi-asserted-by":"crossref","first-page":"287","DOI":"10.3389\/fimmu.2012.00287","article-title":"The danger theory: 20 years later","volume":"3","author":"Pradeu","year":"2012","journal-title":"Front Immunol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0225","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1002\/jnr.23690","article-title":"The basolateral amygdala GABAergic system in health and disease","volume":"94","author":"Prager","year":"2016","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0230","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0013-4694(72)90177-0","article-title":"Modification of seizure activity by electrical stimulation. II. Motor seizure","volume":"32","author":"Racine","year":"1972","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0235","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/bdi.12364","article-title":"Differential effect of Lithium on cell number in Hippocampus and prefrontal cortex in adult mice: a stereological study","volume":"18","author":"Rajkowska","year":"2016","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0240","first-page":"726","article-title":"Neuroimmune interactions and pain: focus on glial-modulating targets","volume":"9","author":"Romero-Sandoval","year":"2008","journal-title":"Curr Opin Investig Drugs"},{"issue":"3","key":"10.1016\/j.neuroscience.2019.06.031_bb6000","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0119717","article-title":"Vitronectin expression in the airways of subjects with asthma and chronic obstructive pulmonary disease","volume":"10","author":"Salazar-Pel\u00e1ez","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0245","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/01.shk.0000196548.10634.02","article-title":"Oral glutamine enhances heat shock protein expression and improves survival following hyperthermia","volume":"25","author":"Singleton","year":"2006","journal-title":"Shock."},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0250","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/hipo.450010106","article-title":"Permanently altered hippocampal structure, excitability, and inhibition after experimental status epilepticus in the rat: the \u201cdormant basket cell\u201d hypothesis and its possible relevance to temporal lobe epilepsy","volume":"1","author":"Sloviter","year":"1991","journal-title":"Hippocampus."},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0255","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/sj.bjp.0706396","article-title":"Heat shock proteins as emerging therapeutic targets","volume":"146","author":"S\u00f5ti","year":"2005","journal-title":"Br J Pharmacol"},{"issue":"10","key":"10.1016\/j.neuroscience.2019.06.031_bb6005","doi-asserted-by":"crossref","first-page":"3031","DOI":"10.1091\/mbc.12.10.3031","article-title":"Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolarplasma membrane microdomains defined by reggie-1 and -2","volume":"12","author":"Stuermer","year":"2001","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0260","doi-asserted-by":"crossref","first-page":"659","DOI":"10.2119\/molmed.2011.00401","article-title":"Toll-like receptor 4 engagement inhibits adenosine 5\u2032-monophosphate\u2013activated protein kinase activation through a high mobility group box 1 protein\u2013dependent mechanism","volume":"18","author":"Tadie","year":"2012","journal-title":"Mol Med"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0265","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1111\/epi.14586","article-title":"Imaging biomarkers of behavioral impairments: a pilot micro\u2013positron emission tomographic study in a rat electrical post\u2013status epilepticus model","volume":"59","author":"van Dijk","year":"2018","journal-title":"Epilepsia."},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0270","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0304-3940(89)90695-2","article-title":"Induction of stress protein HSP70 in nerve cells after status epilepticus in the rat","volume":"100","author":"Vass","year":"1989","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0275","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3389\/fneur.2014.00259","article-title":"The piriform cortex and human focal epilepsy","volume":"5","author":"Vaughan","year":"2014","journal-title":"Front Neurol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0280","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/nrneurol.2010.178","article-title":"The role of inflammation in epilepsy","volume":"7","author":"Vezzani","year":"2011","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0285","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.expneurol.2011.09.033","article-title":"Epilepsy and brain inflammation","volume":"244","author":"Vezzani","year":"2013","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0290","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.neuroscience.2018.06.031","article-title":"Genetic modulation of HSPA1A accelerates kindling progression and exerts pro-convulsant effects","volume":"386","author":"von R\u00fcden","year":"2018","journal-title":"Neuroscience."},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0295","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1021\/acschemneuro.8b00475","article-title":"Genetic and pharmacological targeting of heat shock protein 70 in the mouse amygdala-kindling model","volume":"10","author":"von R\u00fcden","year":"2018","journal-title":"ACS Chem Nerosci"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0300","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.bbi.2015.12.007","article-title":"Proteomic profiling of epileptogenesis in a rat model: focus on inflammation","volume":"53","author":"Walker","year":"2016","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0305","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1002\/ar.1092310411","article-title":"Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator","volume":"231","author":"West","year":"1991","journal-title":"Anat Rec"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0310","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1465-9921-10-31","article-title":"Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via toll-like receptor (TLR)-4","volume":"10","author":"Wheeler","year":"2009","journal-title":"Respir Res"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0315","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s00401-007-0297-3","article-title":"Heat shock protein 70 expression in epilepsy suggests stress rather than protection","volume":"115","author":"Yang","year":"2008","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0320","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1002\/ana.410440403","article-title":"Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy","volume":"44","author":"Yenari","year":"1998","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0325","doi-asserted-by":"crossref","first-page":"2592","DOI":"10.1111\/j.1582-4934.2010.01127.x","article-title":"Endogenous toll-like receptor ligands and their biological significance","volume":"14","author":"Yu","year":"2010","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0335","doi-asserted-by":"crossref","first-page":"6052","DOI":"10.1523\/JNEUROSCI.22-14-06052.2002","article-title":"Relations between brain pathology and temporal lobe epilepsy","volume":"22","author":"Zhang","year":"2002","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0340","doi-asserted-by":"crossref","first-page":"3048","DOI":"10.1002\/dvdy.22441","article-title":"Fluorescent whole-mount method for visualizing three-dimensional relationships in intact and regenerating adult newt spinal cords","volume":"239","author":"Zukor","year":"2010","journal-title":"Dev Dyn"},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0345","unstructured":"https:\/\/scicrunch.org\/resources (date last accessed: January 24th, 2019)."},{"key":"10.1016\/j.neuroscience.2019.06.031_bb0350","unstructured":"www.randomizer.org (date last accessed: October 15th, 2018)."}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452219304488?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452219304488?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T13:42:52Z","timestamp":1777556572000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452219304488"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":70,"alternative-id":["S0306452219304488"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2019.06.031","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epileptogenesis-Associated Alterations of Heat Shock Protein 70 in a Rat Post-Status Epilepticus Model","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2019.06.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Author(s). Published by Elsevier Ltd on behalf of IBRO.","name":"copyright","label":"Copyright"}]}}