{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:17:03Z","timestamp":1790813823639,"version":"4.1.0"},"reference-count":289,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,8,18]],"date-time":"2020-08-18T00:00:00Z","timestamp":1597708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006390","name":"Universit\u00e9 de Lausanne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006390","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ibroneuroscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.neuroscience.2020.07.034","type":"journal-article","created":{"date-parts":[[2020,7,28]],"date-time":"2020-07-28T02:29:24Z","timestamp":1595903364000},"page":"12-30","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["Modelling Learning and Memory in Drosophila to Understand Intellectual Disabilities"],"prefix":"10.1016","volume":"445","author":[{"given":"Vittoria","family":"Mariano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tilmann","family":"Achsel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Bagni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandros K.","family":"Kanellopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2020.07.034_b0005","unstructured":"AAIDD (2010) American Association on Intellectual and Developmental Disabilities, http:\/\/www.aamr.org\/."},{"key":"10.1016\/j.neuroscience.2020.07.034_b0010","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1534\/genetics.107.072280","article-title":"In vivo functional specificity and homeostasis of Drosophila 14-3-3 proteins","volume":"177","author":"Acevedo","year":"2007","journal-title":"Genetics"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0015","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1126\/science.206.4414.93","article-title":"Learning in normal and mutant Drosophila larvae","volume":"206","author":"Aceves-Pina","year":"1979","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0020","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.cub.2010.04.039","article-title":"The leucokinin pathway and its neurons regulate meal size in Drosophila","volume":"20","author":"Al-Anzi","year":"2010","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0025","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.neuron.2009.07.021","article-title":"Obesity-blocking neurons in Drosophila","volume":"63","author":"Al-Anzi","year":"2009","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0030","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1152\/physrev.00017.2008","article-title":"Transcription factors in long-term memory and synaptic plasticity","volume":"89","author":"Alberini","year":"2009","journal-title":"Physiol Rev"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0035","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.54074","article-title":"A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord","volume":"9","author":"Allen","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0040","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders Fifth Ed, DSM-5.","DOI":"10.1176\/appi.books.9780890425596"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0045","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.04580","article-title":"Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila","volume":"3","author":"Aso","year":"2014","journal-title":"Elife"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0055","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.04577","article-title":"The neuronal architecture of the mushroom body provides a logic for associative learning","volume":"3","author":"Aso","year":"2014","journal-title":"Elife"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0050","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.16135","article-title":"Dopaminergic neurons write and update memories with cell-type-specific rules","volume":"5","author":"Aso","year":"2016","journal-title":"Elife"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0060","doi-asserted-by":"crossref","first-page":"4314","DOI":"10.1172\/JCI63141","article-title":"Fragile X syndrome: causes, diagnosis, mechanisms, and therapeutics","volume":"122","author":"Bagni","year":"2012","journal-title":"J Clin Invest"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0065","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/j.neuron.2019.02.041","article-title":"A synaptic perspective of fragile X syndrome and autism spectrum disorders","volume":"101","author":"Bagni","year":"2019","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0070","doi-asserted-by":"crossref","first-page":"15996","DOI":"10.1073\/pnas.1019012108","article-title":"Neurofibromatosis-1 regulates mTOR-mediated astrocyte growth and glioma formation in a TSC\/Rheb-independent manner","volume":"108","author":"Banerjee","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0075","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.neuron.2010.05.020","article-title":"Drosophila neuroligin 1 promotes growth and postsynaptic differentiation at glutamatergic neuromuscular junctions","volume":"66","author":"Banovic","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0080","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0020800","article-title":"The serotonin 5-HT7Dro receptor is expressed in the brain of Drosophila, and is essential for normal courtship and mating","volume":"6","author":"Becnel","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0085","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/j.celrep.2013.08.003","article-title":"DREADDs in Drosophila: a pharmacogenetic approach for controlling behavior, neuronal signaling, and physiology in the fly","volume":"4","author":"Becnel","year":"2013","journal-title":"Cell Rep"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0090","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1534\/genetics.111.126995","article-title":"The Drosophila gene disruption project: progress using transposons with distinctive site specificities","volume":"188","author":"Bellen","year":"2011","journal-title":"Genetics"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0095","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/nrn2839","article-title":"100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future","volume":"11","author":"Bellen","year":"2010","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0100","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.neuron.2012.04.007","article-title":"Dopamine is required for learning and forgetting in Drosophila","volume":"74","author":"Berry","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2018.09.051","article-title":"Dopamine Neurons mediate learning and forgetting through bidirectional modulation of a memory trace","volume":"25","author":"Berry","year":"2018","journal-title":"Cell Rep"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0110","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1016\/j.celrep.2017.07.038","article-title":"The conserved, disease-associated RNA binding protein dNab2 interacts with the Fragile X protein ortholog in Drosophila neurons","volume":"20","author":"Bienkowski","year":"2017","journal-title":"Cell Rep"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0115","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1242\/dev.088757","article-title":"A versatile platform for creating a comprehensive UAS-ORFeome library in Drosophila","volume":"140","author":"Bischof","year":"2013","journal-title":"Development"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0120","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/ajmg.b.30287","article-title":"Absence of coding mutations in the X-linked genes neuroligin 3 and neuroligin 4 in individuals with autism from the IMGSAC collection","volume":"141B","author":"Blasi","year":"2006","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0125","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/ejhg.2012.175","article-title":"Prevalence of SHANK3 variants in patients with different subtypes of autism spectrum disorders","volume":"21","author":"Boccuto","year":"2013","journal-title":"Eur J Hum Genet: EJHG"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0130","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1038\/nn.2175","article-title":"Excess protein synthesis in Drosophila fragile X mutants impairs long-term memory","volume":"11","author":"Bolduc","year":"2008","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0135","doi-asserted-by":"crossref","first-page":"22","DOI":"10.3389\/neuro.04.022.2009","article-title":"Fragile x mental retardation 1 and filamin a interact genetically in Drosophila long-term memory","volume":"3","author":"Bolduc","year":"2010","journal-title":"Front Neural Circuits"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0140","doi-asserted-by":"crossref","first-page":"91","DOI":"10.4161\/fly.3.1.7812","article-title":"Fruit flies and intellectual disability","volume":"3","author":"Bolduc","year":"2009","journal-title":"Fly (Austin)"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0145","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1146\/annurev-genom-091416-035332","article-title":"Cognitive dysfunctions in intellectual disabilities: the contributions of the Ras-MAPK and PI3K-AKT-mTOR pathways","volume":"18","author":"Borrie","year":"2017","journal-title":"Annu Rev Genomics Hum Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0150","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.neuron.2015.03.042","article-title":"The GABAA receptor as a therapeutic target for neurodevelopmental disorders","volume":"86","author":"Braat","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0155","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/S1470-2045(09)70033-6","article-title":"Mechanisms in the pathogenesis of malignant tumours in neurofibromatosis type 1","volume":"10","author":"Brems","year":"2009","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0160","first-page":"47","article-title":"The role of dopamine in schizophrenia from a neurobiological and evolutionary perspective: old fashioned, but still in vogue","volume":"5","author":"Brisch","year":"2014","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0165","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0044888","article-title":"The small GTPase Rheb affects central brain neuronal morphology and memory formation in Drosophila","volume":"7","author":"Brown","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0170","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.50354","article-title":"Single cell transcriptome atlas of the Drosophila larval brain","volume":"8","author":"Brunet Avalos","year":"2019","journal-title":"Elife"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0175","doi-asserted-by":"crossref","first-page":"10135","DOI":"10.1523\/JNEUROSCI.0283-10.2010","article-title":"A distinct set of Drosophila brain neurons required for neurofibromatosis type 1-dependent learning and memory","volume":"30","author":"Buchanan","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0180","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/nature11614","article-title":"Layered reward signalling through octopamine and dopamine in Drosophila","volume":"492","author":"Burke","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0185","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1111\/jir.12382","article-title":"Clinical and genetic aspects of the 15q11.2 BP1-BP2 microdeletion disorder","volume":"61","author":"Butler","year":"2017","journal-title":"J Intellect Disabil Res"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0190","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1002\/ajmg.a.36554","article-title":"Phenotypic features in patients with 15q11.2(BP1-BP2) deletion: further delineation of an emerging syndrome","volume":"164A","author":"Cafferkey","year":"2014","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0195","doi-asserted-by":"crossref","first-page":"R11","DOI":"10.1016\/j.cub.2009.10.031","article-title":"The mushroom body","volume":"20","author":"Campbell","year":"2010","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0200","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.bbrc.2015.04.110","article-title":"The E3 ligase ube3a is required for learning in Drosophila melanogaster","volume":"462","author":"Chakraborty","year":"2015","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0205","doi-asserted-by":"crossref","first-page":"9958","DOI":"10.1523\/JNEUROSCI.1728-10.2010","article-title":"Angelman syndrome, a genomic imprinting disorder of the brain","volume":"30","author":"Chamberlain","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0210","doi-asserted-by":"crossref","first-page":"15794","DOI":"10.1073\/pnas.2536696100","article-title":"The Drosophila homolog of Down's syndrome critical region 1 gene regulates learning: implications for mental retardation","volume":"100","author":"Chang","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0215","doi-asserted-by":"crossref","first-page":"5664","DOI":"10.1073\/pnas.082102599","article-title":"Fighting fruit flies: a model system for the study of aggression","volume":"99","author":"Chen","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0220","doi-asserted-by":"crossref","first-page":"16018","DOI":"10.1523\/JNEUROSCI.1685-12.2012","article-title":"Drosophila neuroligin 2 is required presynaptically and postsynaptically for proper synaptic differentiation and synaptic transmission","volume":"32","author":"Chen","year":"2012","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0225","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3389\/fpsyt.2016.00061","article-title":"GABA system in schizophrenia and mood disorders: a mini review on third-generation imaging studies","volume":"7","author":"Chiapponi","year":"2016","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0230","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1093\/nar\/30.1.149","article-title":"Homophila: human disease gene cognates in Drosophila","volume":"30","author":"Chien","year":"2002","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0235","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1601-183x.2004.00061.x","article-title":"Habituation of an odorant-induced startle response in Drosophila","volume":"3","author":"Cho","year":"2004","journal-title":"Genes Brain Behav"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0240","doi-asserted-by":"crossref","first-page":"90","DOI":"10.3389\/fped.2014.00090","article-title":"Exploring the complexity of intellectual disability in fetal alcohol spectrum disorders","volume":"2","author":"Chokroborty-Hoque","year":"2014","journal-title":"Front Pediatr"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0245","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1242\/dmm.004598","article-title":"Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P","volume":"3","author":"Coffee","year":"2010","journal-title":"Dis Model Mech"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0250","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1093\/hmg\/ddr527","article-title":"In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation","volume":"21","author":"Coffee","year":"2012","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0255","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1016\/j.cell.2015.11.019","article-title":"Coordinated and compartmentalized neuromodulation shapes sensory processing in Drosophila","volume":"163","author":"Cohn","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0260","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.039180","article-title":"Intellectual disability and autism spectrum disorders 'on the fly': insights from Drosophila","volume":"12","author":"Coll-Tan\u00e9","year":"2019","journal-title":"Dis Model Mech"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0265","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1038\/ng.909","article-title":"A copy number variation morbidity map of developmental delay","volume":"43","author":"Cooper","year":"2011","journal-title":"Nat Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0270","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.34550","article-title":"Cellular diversity in the Drosophila midbrain revealed by single-cell transcriptomics","volume":"7","author":"Croset","year":"2018","journal-title":"Elife"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0275","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/S1474-4422(15)00069-1","article-title":"Neurological and neuropsychiatric aspects of tuberous sclerosis complex","volume":"14","author":"Curatolo","year":"2015","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0280","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.tins.2007.06.003","article-title":"The GABAA receptor: a novel target for treatment of fragile X?","volume":"30","author":"D'Hulst","year":"2007","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0285","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1126\/science.1252114","article-title":"FoxP influences the speed and accuracy of a perceptual decision in Drosophila","volume":"344","author":"DasGupta","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2019.01.092","article-title":"Autism and schizophrenia-associated CYFIP1 regulates the balance of synaptic excitation and inhibition","volume":"26","author":"Davenport","year":"2019","journal-title":"Cell Rep"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0295","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2018.05.057","article-title":"A single-cell transcriptome atlas of the aging Drosophila brain","volume":"174","author":"Davie","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0300","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.neuron.2004.09.008","article-title":"Olfactory learning","volume":"44","author":"Davis","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0305","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1146\/annurev.neuro.28.061604.135651","article-title":"Olfactory memory formation in Drosophila: from molecular to systems neuroscience","volume":"28","author":"Davis","year":"2005","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0310","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0074-7742(04)59009-8","article-title":"Postsynaptic density scaffolding proteins at excitatory synapse and disorders of synaptic plasticity: implications for human behavior pathologies","volume":"59","author":"de Bartolomeis","year":"2004","journal-title":"Int Rev Neurobiol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0315","doi-asserted-by":"crossref","first-page":"118","DOI":"10.3389\/fpsyt.2017.00118","article-title":"GABAergic mechanisms in schizophrenia: linking postmortem and in vivo studies","volume":"8","author":"de Jonge","year":"2017","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0320","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1056\/NEJMoa1206524","article-title":"Diagnostic exome sequencing in persons with severe intellectual disability","volume":"367","author":"de Ligt","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0325","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/nature13772","article-title":"Synaptic, transcriptional and chromatin genes disrupted in autism","volume":"515","author":"De Rubeis","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0330","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/nmeth.1800","article-title":"Power tools for gene expression and clonal analysis in Drosophila","volume":"9","author":"del Valle","year":"2011","journal-title":"Nat Methods"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0335","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/0166-2236(95)93905-D","article-title":"Dissection of memory formation: from behavioral pharmacology to molecular genetics","volume":"18","author":"DeZazzo","year":"1995","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0340","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1523\/JNEUROSCI.22-02-00428.2002","article-title":"Mutation of Drosophila homer disrupts control of locomotor activity and behavioral plasticity","volume":"22","author":"Diagana","year":"2002","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0345","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/nature05954","article-title":"A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila","volume":"448","author":"Dietzl","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0350","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.43079","article-title":"Neurogenetic dissection of the Drosophila lateral horn reveals major outputs, diverse behavioural functions, and interactions with the mushroom body","volume":"8","author":"Dolan","year":"2019","journal-title":"Elife"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0355","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1242\/dev.117127","article-title":"Activity-dependent FMRP requirements in development of the neural circuitry of learning and memory","volume":"142","author":"Doll","year":"2015","journal-title":"Development"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0360","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.nbd.2016.02.006","article-title":"Neuron class-specific requirements for Fragile X Mental Retardation Protein in critical period development of calcium signaling in learning and memory circuitry","volume":"89","author":"Doll","year":"2016","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0365","doi-asserted-by":"crossref","first-page":"7644","DOI":"10.1073\/pnas.1602152113","article-title":"Inability to activate Rac1-dependent forgetting contributes to behavioral inflexibility in mutants of multiple autism-risk genes","volume":"113","author":"Dong","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0370","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1073\/pnas.73.5.1684","article-title":"dunce, a mutant of Drosophila deficient in learning","volume":"73","author":"Dudai","year":"1976","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0375","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/nature23455","article-title":"The complete connectome of a learning and memory centre in an insect brain","volume":"548","author":"Eichler","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0380","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1146\/annurev-neuro-062111-150433","article-title":"Evolution of synapse complexity and diversity","volume":"35","author":"Emes","year":"2012","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0385","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.asd.2011.02.004","article-title":"Are mushroom bodies cerebellum-like structures?","volume":"40","author":"Farris","year":"2011","journal-title":"Arthropod Struct Dev"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0390","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1038\/35006074","article-title":"A Drosophila model of Parkinson's disease","volume":"404","author":"Feany","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0395","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.neulet.2006.08.017","article-title":"High frequency of neurexin 1beta signal peptide structural variants in patients with autism","volume":"409","author":"Feng","year":"2006","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0400","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1002\/dneu.20700","article-title":"Drosophila RSK negatively regulates bouton number at the neuromuscular junction","volume":"69","author":"Fischer","year":"2009","journal-title":"Dev Neurobiol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0405","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1038\/mp.2016.15","article-title":"DISC1 causes associative memory and neurodevelopmental defects in fruit flies","volume":"21","author":"Furukubo-Tokunaga","year":"2016","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0410","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.nlm.2013.04.014","article-title":"Modulation of behavior by scaffolding proteins of the post-synaptic density","volume":"105","author":"Gao","year":"2013","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0415","doi-asserted-by":"crossref","first-page":"146","DOI":"10.2174\/1566524015666150303003028","article-title":"Common mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disorders","volume":"15","author":"Gao","year":"2015","journal-title":"Curr Mol Med"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0420","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.conb.2011.04.009","article-title":"Drosophila modeling of heritable neurodevelopmental disorders","volume":"21","author":"Gatto","year":"2011","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0425","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.nbd.2014.01.008","article-title":"GABAergic circuit dysfunction in the Drosophila Fragile X syndrome model","volume":"65","author":"Gatto","year":"2014","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0430","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1534\/g3.111.000869","article-title":"Genome-wide survey of large rare copy number variants in Alzheimer's disease among Caribbean hispanics","volume":"2","author":"Ghani","year":"2012","journal-title":"G3 (Bethesda)"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0435","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/nature13394","article-title":"Genome sequencing identifies major causes of severe intellectual disability","volume":"511","author":"Gilissen","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0440","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/nature07953","article-title":"Autism genome-wide copy number variation reveals ubiquitin and neuronal genes","volume":"459","author":"Glessner","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0445","doi-asserted-by":"crossref","first-page":"7701","DOI":"10.1523\/JNEUROSCI.0784-18.2018","article-title":"The Drosophila receptor tyrosine kinase Alk constrains long-term memory formation","volume":"38","author":"Gouzi","year":"2018","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0450","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1002281","article-title":"The receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning","volume":"7","author":"Gouzi","year":"2011","journal-title":"PLoS Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0455","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.cell.2004.11.035","article-title":"Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins","volume":"119","author":"Graf","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0460","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0892-0362(97)00097-4","article-title":"Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury","volume":"19","author":"Grandjean","year":"1997","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0465","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/978-1-4939-2687-9_22","article-title":"Precise genome editing of Drosophila with CRISPR RNA-guided Cas9","volume":"1311","author":"Gratz","year":"2015","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0470","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/0471142727.mb3102s111","article-title":"CRISPR-Cas9 genome editing in Drosophila","volume":"111","author":"Gratz","year":"2015","journal-title":"Curr Protoc Mol Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0475","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1534\/genetics.113.160713","article-title":"Highly specific and efficient CRISPR\/Cas-9-catalyzed homology-directed repair in Drosophila","volume":"196","author":"Gratz","year":"2014","journal-title":"Genetics"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0480","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.cell.2010.01.026","article-title":"The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc","volume":"140","author":"Greer","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0485","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.cell.2018.03.075","article-title":"Dendritic integration of sensory evidence in perceptual decision-making","volume":"173","author":"Groschner","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0490","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.celrep.2015.03.065","article-title":"Selective role of the catalytic PI3K subunit p110beta in impaired higher order cognition in fragile X syndrome","volume":"11","author":"Gross","year":"2015","journal-title":"Cell Rep"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0495","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/sleep\/34.3.273","article-title":"Go signaling in mushroom bodies regulates sleep in Drosophila","volume":"34","author":"Guo","year":"2011","journal-title":"Sleep"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0500","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/35002593","article-title":"A neurofibromatosis-1-regulated pathway is required for learning in Drosophila","volume":"403","author":"Guo","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0505","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1101\/lm.034363.114","article-title":"Functional neuroanatomy of Drosophila olfactory memory formation","volume":"21","author":"Guven-Ozkan","year":"2014","journal-title":"Learn Mem"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0510","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.ajhg.2011.02.001","article-title":"Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability","volume":"88","author":"Hamdan","year":"2011","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0515","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1004772","article-title":"De novo mutations in moderate or severe intellectual disability","volume":"10","author":"Hamdan","year":"2014","journal-title":"PLoS Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0520","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1093\/hmg\/ddl023","article-title":"Effect of neurofibromatosis type I mutations on a novel pathway for adenylyl cyclase activation requiring neurofibromin and Ras","volume":"15","author":"Hannan","year":"2006","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0525","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a026864","article-title":"The use of next-generation sequencing for research and diagnostics for intellectual disability","volume":"7","author":"Harripaul","year":"2017","journal-title":"Cold Spring Harb Perspect Med"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0530","doi-asserted-by":"crossref","first-page":"5820","DOI":"10.1523\/JNEUROSCI.4279-15.2016","article-title":"Shank modulates postsynaptic Wnt signaling to regulate synaptic development","volume":"36","author":"Harris","year":"2016","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0535","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.1242\/jcs.02950","article-title":"RSK and MSK in MAP kinase signalling","volume":"119","author":"Hauge","year":"2006","journal-title":"J Cell Sci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0540","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.03868","article-title":"A single pair of neurons links sleep to memory consolidation in Drosophila melanogaster","volume":"4","author":"Haynes","year":"2015","journal-title":"Elife"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0545","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neubiorev.2016.01.007","article-title":"Role of GABA(B) receptors in learning and memory and neurological disorders","volume":"63","author":"Heaney","year":"2016","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0550","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/nrn1074","article-title":"Mushroom body memoir: from maps to models","volume":"4","author":"Heisenberg","year":"2003","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0555","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/01677068509100140","article-title":"Drosophila mushroom body mutants are deficient in olfactory learning","volume":"2","author":"Heisenberg","year":"1985","journal-title":"J Neurogenet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0560","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0896-6273(00)80877-6","article-title":"Rest in Drosophila is a sleep-like state","volume":"25","author":"Hendricks","year":"2000","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0565","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.nlm.2007.09.010","article-title":"The role of protein synthesis in memory consolidation: progress amid decades of debate","volume":"89","author":"Hernandez","year":"2008","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0570","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/nature15396","article-title":"Plasticity-driven individualization of olfactory coding in mushroom body output neurons","volume":"526","author":"Hige","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0575","doi-asserted-by":"crossref","first-page":"6852","DOI":"10.1523\/JNEUROSCI.0933-07.2007","article-title":"Distinct functional domains of neurofibromatosis type 1 regulate immediate versus long-term memory formation","volume":"27","author":"Ho","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0580","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1111\/j.1601-183X.2012.00768.x","article-title":"Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome","volume":"11","author":"Hoeffer","year":"2012","journal-title":"Genes Brain Behav"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0585","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1037\/0894-4105.22.1.36","article-title":"Executive functions in young males with fragile X syndrome in comparison to mental age-matched controls: baseline findings from a longitudinal study","volume":"22","author":"Hooper","year":"2008","journal-title":"Neuropsychology"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0590","doi-asserted-by":"crossref","first-page":"4154","DOI":"10.1073\/pnas.73.11.4154","article-title":"Courtship in Drosophila mosaics: sex-specific foci for sequential action patterns","volume":"73","author":"Hotta","year":"1976","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0595","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1177\/0269881114563634","article-title":"Glutamate and dopamine in schizophrenia: an update for the 21st century","volume":"29","author":"Howes","year":"2015","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0600","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1212\/01.wnl.0000179303.72345.ce","article-title":"The nature and frequency of cognitive deficits in children with neurofibromatosis type 1","volume":"65","author":"Hyman","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0605","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1038\/nature13908","article-title":"The contribution of de novo coding mutations to autism spectrum disorder","volume":"515","author":"Iossifov","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0610","doi-asserted-by":"crossref","first-page":"8253","DOI":"10.1073\/pnas.0702726104","article-title":"Prandiology of Drosophila and the CAFE assay","volume":"104","author":"Ja","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0615","doi-asserted-by":"crossref","first-page":"3825","DOI":"10.1093\/hmg\/ddy291","article-title":"Protein synthesis levels are increased in a subset of individuals with fragile X syndrome","volume":"27","author":"Jacquemont","year":"2018","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0620","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.neuroscience.2011.06.058","article-title":"Serotonin receptor activity is necessary for olfactory learning and memory in Drosophila melanogaster","volume":"192","author":"Johnson","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0625","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1093\/schbul\/sbq135","article-title":"DISC1 in schizophrenia: genetic mouse models and human genomic imaging","volume":"37","author":"Johnstone","year":"2011","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0630","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1017\/S0033291702007092","article-title":"Learning disability and epilepsy in an epidemiological sample of individuals with tuberous sclerosis complex","volume":"33","author":"Joinson","year":"2003","journal-title":"Psychol Med"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0635","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1534\/g3.118.200867","article-title":"New Drosophila long-term memory genes revealed by assessing computational function prediction methods","volume":"9","author":"Kacsoh","year":"2019","journal-title":"G3 (Bethesda)"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0640","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/B978-0-12-387003-2.00006-9","article-title":"Learning and memory in Drosophila: behavior, genetics, and neural systems","volume":"99","author":"Kahsai","year":"2011","journal-title":"Int Rev Neurobiol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0645","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/j.cell.2020.02.044","article-title":"Aralar sequesters GABA into hyperactive mitochondria, causing social behavior deficits","volume":"180","author":"Kanellopoulos","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0650","doi-asserted-by":"crossref","first-page":"13111","DOI":"10.1523\/JNEUROSCI.1347-12.2012","article-title":"Learning and memory deficits consequent to reduction of the fragile X mental retardation protein result from metabotropic glutamate receptor-mediated inhibition of cAMP signaling in Drosophila","volume":"32","author":"Kanellopoulos","year":"2012","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0655","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.neures.2017.10.012","article-title":"Neurexins and neuropsychiatric disorders","volume":"127","author":"Kasem","year":"2018","journal-title":"Neurosci Res"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0660","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.conb.2016.12.011","article-title":"Dopaminergic rules of engagement for memory in Drosophila","volume":"43","author":"Kaun","year":"2017","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0665","article-title":"High-throughput sequencing of mGluR signaling pathway genes reveals enrichment of rare variants in autism","volume":"7","author":"Kelleher","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0670","doi-asserted-by":"crossref","first-page":"7640","DOI":"10.1523\/JNEUROSCI.1167-07.2007","article-title":"D1 dopamine receptor dDA1 is required in the mushroom body neurons for aversive and appetitive learning in Drosophila","volume":"27","author":"Kim","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0675","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3389\/fncel.2013.00072","article-title":"Genetic and pharmacological manipulations of the serotonergic system in early life: neurodevelopmental underpinnings of autism-related behavior","volume":"7","author":"Kinast","year":"2013","journal-title":"Front Cell Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0680","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1074\/jbc.273.1.291","article-title":"p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase","volume":"273","author":"Kobayashi","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0685","first-page":"55808","article-title":"Drosophila courtship conditioning as a measure of learning and memory","volume":"124","author":"Koemans","year":"2017","journal-title":"J Vis Exp"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0690","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1073\/pnas.68.9.2112","article-title":"Clock mutants of Drosophila melanogaster","volume":"68","author":"Konopka","year":"1971","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0695","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.cell.2009.08.035","article-title":"A neural circuit mechanism integrating motivational state with memory expression in Drosophila","volume":"139","author":"Krashes","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0700","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1016\/j.celrep.2015.05.037","article-title":"Synaptic Orb2A bridges memory acquisition and late memory consolidation in Drosophila","volume":"11","author":"Kr\u00fcttner","year":"2015","journal-title":"Cell Rep"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0705","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1080\/19336934.2016.1220463","article-title":"Tools and strategies for scarless allele replacement in Drosophila using CRISPR\/Cas9","volume":"11","author":"Lamb","year":"2017","journal-title":"Fly (Austin)"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0710","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1086\/382137","article-title":"X-linked mental retardation and autism are associated with a mutation in the NLGN4 gene, a member of the neuroligin family","volume":"74","author":"Laumonnier","year":"2004","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0715","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1002521","article-title":"Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders","volume":"8","author":"Leblond","year":"2012","journal-title":"PLoS Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0720","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1004580","article-title":"Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairments","volume":"10","author":"Leblond","year":"2014","journal-title":"PLoS Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0725","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1038\/nn.4352","article-title":"Meta-analysis of 2,104 trios provides support for 10 new genes for intellectual disability","volume":"19","author":"Lelieveld","year":"2016","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0730","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.neuron.2012.09.013","article-title":"Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders","volume":"76","author":"Lesch","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0735","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1016\/j.cell.2017.10.019","article-title":"Classifying Drosophila olfactory projection neuron subtypes by single-cell RNA sequencing","volume":"171","author":"Li","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0740","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.38709","article-title":"An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila","volume":"7","author":"Li-Kroeger","year":"2018","journal-title":"Elife"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0745","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/nn.3660","article-title":"Sparse, decorrelated odor coding in the mushroom body enhances learned odor discrimination","volume":"17","author":"Lin","year":"2014","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0750","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1038\/nn.3827","article-title":"Neural correlates of water reward in thirsty Drosophila","volume":"17","author":"Lin","year":"2014","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0755","doi-asserted-by":"crossref","DOI":"10.1016\/j.cub.2019.08.079","article-title":"A serotonin-modulated circuit controls sleep architecture to regulate cognitive function independent of total sleep in Drosophila","volume":"29","author":"Liu","year":"2019","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0760","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1038\/nature11304","article-title":"A subset of dopamine neurons signals reward for odour memory in Drosophila","volume":"488","author":"Liu","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0765","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1523\/JNEUROSCI.4763-08.2009","article-title":"The GABAA receptor RDL suppresses the conditioned stimulus pathway for olfactory learning","volume":"29","author":"Liu","year":"2009","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0770","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/nn.2235","article-title":"The GABAergic anterior paired lateral neuron suppresses and is suppressed by olfactory learning","volume":"12","author":"Liu","year":"2009","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0775","doi-asserted-by":"crossref","first-page":"349","DOI":"10.3389\/fgene.2018.00349","article-title":"Prioritized high-confidence risk genes for intellectual disability reveal molecular convergence during brain development","volume":"9","author":"Liu","year":"2018","journal-title":"Front Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0780","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0092-8674(84)90316-7","article-title":"Loss of calcium\/calmodulin responsiveness in adenylate cyclase of rutabaga, a Drosophila learning mutant","volume":"37","author":"Livingstone","year":"1984","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0785","doi-asserted-by":"crossref","first-page":"R1010","DOI":"10.1016\/j.cub.2017.08.023","article-title":"Collective behavior: social digging in Drosophila larvae","volume":"27","author":"Louis","year":"2017","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0790","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1093\/hmg\/ddn373","article-title":"The Drosophila homologue of the Angelman syndrome ubiquitin ligase regulates the formation of terminal dendritic branches","volume":"18","author":"Lu","year":"2009","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0795","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1111\/j.1469-8749.2008.03027.x","article-title":"Serotonin and dopamine transporter binding in children with autism determined by SPECT","volume":"50","author":"Makkonen","year":"2008","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0800","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.tibs.2003.09.003","article-title":"Rheb fills a GAP between TSC and TOR","volume":"28","author":"Manning","year":"2003","journal-title":"Trends Biochem Sci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0805","doi-asserted-by":"crossref","first-page":"R700","DOI":"10.1016\/j.cub.2005.08.024","article-title":"Deconstructing memory in Drosophila","volume":"15","author":"Margulies","year":"2005","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0810","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/ejhg.2009.189","article-title":"Coffin-Lowry syndrome","volume":"18","author":"Marques Pereira","year":"2010","journal-title":"Eur J Hum Genet: EJHG"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0815","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/S0092-8674(00)80484-5","article-title":"Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: a function for local protein synthesis in memory storage","volume":"91","author":"Martin","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0820","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.ridd.2010.12.018","article-title":"Prevalence of intellectual disability: a meta-analysis of population-based studies","volume":"32","author":"Maulik","year":"2011","journal-title":"Res Dev Disabil"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0825","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.neuron.2005.01.038","article-title":"Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome","volume":"45","author":"McBride","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0830","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/S0896-6273(00)81043-0","article-title":"Mushroom body ablation impairs short-term memory and long-term memory of courtship conditioning in Drosophila melanogaster","volume":"24","author":"McBride","year":"1999","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0835","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1534\/genetics.115.179457","article-title":"Drosophila as an in vivo model for human neurodegenerative disease","volume":"201","author":"McGurk","year":"2015","journal-title":"Genetics"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0840","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1007\/s40474-016-0085-7","article-title":"Systematic review of the prevalence and incidence of intellectual disabilities: current trends and issues","volume":"3","author":"McKenzie","year":"2016","journal-title":"Curr Dev Disord Rep"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0845","doi-asserted-by":"crossref","first-page":"4253","DOI":"10.1093\/hmg\/ddq348","article-title":"Kismet\/CHD7 regulates axon morphology, memory and locomotion in a Drosophila model of CHARGE syndrome","volume":"19","author":"Melicharek","year":"2010","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0850","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.neuron.2012.03.039","article-title":"Mg(2+) block of Drosophila NMDA receptors is required for long-term memory formation and CREB-dependent gene expression","volume":"74","author":"Miyashita","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0855","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0164516","article-title":"Memory elicited by courtship conditioning requires mushroom body neuronal subsets similar to those utilized in appetitive memory","volume":"11","author":"Montague","year":"2016","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0860","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1207\/s15326942dn3003_8","article-title":"Learning disabilities and intellectual functioning in school-aged children with prenatal cocaine exposure","volume":"30","author":"Morrow","year":"2006","journal-title":"Dev Neuropsychol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0865","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.neuroscience.2015.11.010","article-title":"The serotonin system in autism spectrum disorder: From biomarker to animal models","volume":"321","author":"Muller","year":"2016","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0870","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1523\/JNEUROSCI.3542-14.2015","article-title":"Gene dosage in the dysbindin schizophrenia susceptibility network differentially affect synaptic function and plasticity","volume":"35","author":"Mullin","year":"2015","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0875","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1001\/archgenpsychiatry.2009.137","article-title":"Brain serotonin and dopamine transporter bindings in adults with high-functioning autism","volume":"67","author":"Nakamura","year":"2010","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0880","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/j.cell.2008.07.031","article-title":"The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP","volume":"134","author":"Napoli","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0885","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1038\/npp.2015.322","article-title":"I believe I can fly!: Use of Drosophila as a model organism in neuropsychopharmacology research","volume":"41","author":"Narayanan","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0890","unstructured":"National Academies of Sciences and Medicine (2015) Mental Disorders and Disabilities among Low-Income Children, (Boat TF, Wu JT, eds). Washington (DC): Washington, DC: The National Academies Press."},{"key":"10.1016\/j.neuroscience.2020.07.034_b0895","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.neuron.2015.07.033","article-title":"Excitatory\/inhibitory balance and circuit homeostasis in autism spectrum disorders","volume":"87","author":"Nelson","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0900","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1038\/nature07003","article-title":"Analysis of a spatial orientation memory in Drosophila","volume":"453","author":"Neuser","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0905","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.neuint.2014.01.002","article-title":"Decoding the contribution of dopaminergic genes and pathways to autism spectrum disorder (ASD)","volume":"66","author":"Nguyen","year":"2014","journal-title":"Neurochem Int"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0910","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/nature10131","article-title":"Visual place learning in Drosophila melanogaster","volume":"474","author":"Ofstad","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0915","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s00221-013-3679-x","article-title":"Serotonergic modulation of hippocampal theta activity in relation to hippocampal information processing","volume":"230","author":"Olvera-Cortes","year":"2013","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0920","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1003911","article-title":"Human intellectual disability genes form conserved functional modules in Drosophila","volume":"9","author":"Oortveld","year":"2013","journal-title":"PLoS Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0925","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.conb.2015.10.002","article-title":"Olfactory learning skews mushroom body output pathways to steer behavioral choice in Drosophila","volume":"35","author":"Owald","year":"2015","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0930","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1016\/j.cub.2004.09.085","article-title":"The Drosophila fragile X gene negatively regulates neuronal elaboration and synaptic differentiation","volume":"14","author":"Pan","year":"2004","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0935","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/ajmg.a.37977","article-title":"Neuroligin 2 nonsense variant associated with anxiety, autism, intellectual disability, hyperphagia, and obesity","volume":"173","author":"Parente","year":"2017","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0940","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/B978-0-12-387003-2.00001-X","article-title":"Seizure and epilepsy: studies of seizure disorders in Drosophila","volume":"99","author":"Parker","year":"2011","journal-title":"Int Rev Neurobiol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0945","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.neuron.2013.08.006","article-title":"Odor discrimination in Drosophila: from neural population codes to behavior","volume":"79","author":"Parnas","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0950","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1159\/000478725","article-title":"A dopamine hypothesis of autism spectrum disorder","volume":"39","author":"Paval","year":"2017","journal-title":"Dev Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0955","doi-asserted-by":"crossref","DOI":"10.1016\/j.cub.2018.04.040","article-title":"A GABAergic feedback shapes dopaminergic input on the Drosophila mushroom body to promote appetitive long-term memory","volume":"28","author":"Pavlowsky","year":"2018","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0960","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1534\/genetics.115.180208","article-title":"The Transgenic RNAi Project at Harvard Medical School: Resources and validation","volume":"201","author":"Perkins","year":"2015","journal-title":"Genetics"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0965","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nature09146","article-title":"Functional impact of global rare copy number variation in autism spectrum disorders","volume":"466","author":"Pinto","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0970","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4161\/fly.3.1.7726","article-title":"There are many ways to train a fly","volume":"3","author":"Pitman","year":"2009","journal-title":"Fly (Austin)"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0975","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.cub.2011.03.069","article-title":"A pair of inhibitory neurons are required to sustain labile memory in the Drosophila mushroom body","volume":"21","author":"Pitman","year":"2011","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0980","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/nature04739","article-title":"A dynamic role for the mushroom bodies in promoting sleep in Drosophila","volume":"441","author":"Pitman","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0985","doi-asserted-by":"crossref","first-page":"12792","DOI":"10.1523\/JNEUROSCI.1638-15.2015","article-title":"Identified serotonin-releasing neurons induce behavioral quiescence and suppress mating in Drosophila","volume":"35","author":"Pooryasin","year":"2015","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0990","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/mp.2013.160","article-title":"DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan","volume":"19","author":"Porteous","year":"2014","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.neuroscience.2020.07.034_b0995","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0092-8674(01)00333-6","article-title":"Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size","volume":"105","author":"Potter","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1000","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/1750-1326-8-35","article-title":"Drosophila melanogaster as a model organism for Alzheimer's disease","volume":"8","author":"Pr\u00fcssing","year":"2013","journal-title":"Mol Neurodegener"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1005","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nature12975","article-title":"A polygenic burden of rare disruptive mutations in schizophrenia","volume":"506","author":"Purcell","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1010","doi-asserted-by":"crossref","first-page":"9745","DOI":"10.1523\/JNEUROSCI.3211-04.2004","article-title":"The S6KII (rsk) gene of Drosophila melanogaster differentially affects an operant and a classical learning task","volume":"24","author":"Putz","year":"2004","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1015","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.cub.2012.02.014","article-title":"Gamma neurons mediate dopaminergic input during aversive olfactory memory formation in Drosophila","volume":"22","author":"Qin","year":"2012","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1020","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1073\/pnas.71.3.708","article-title":"Conditioned behavior in Drosophila melanogaster","volume":"71","author":"Quinn","year":"1974","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1025","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1038\/277212a0","article-title":"The Drosophila memory mutant amnesiac","volume":"277","author":"Quinn","year":"1979","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1030","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1101\/gr.169101","article-title":"A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster","volume":"11","author":"Reiter","year":"2001","journal-title":"Genome Res"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1035","doi-asserted-by":"crossref","first-page":"11524","DOI":"10.1523\/JNEUROSCI.0827-12.2012","article-title":"A GABAergic inhibitory neural circuit regulates visual reversal learning in Drosophila","volume":"32","author":"Ren","year":"2012","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1040","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/cercor\/bhj144","article-title":"Neuroanatomical correlates of memory deficits in tuberous sclerosis complex","volume":"17","author":"Ridler","year":"2007","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1045","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1073\/pnas.1010930108","article-title":"Behavioral consequences of dopamine deficiency in the Drosophila central nervous system","volume":"108","author":"Riemensperger","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1050","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.cub.2016.01.012","article-title":"Four individually identified paired dopamine neurons signal reward in larval Drosophila","volume":"26","author":"Rohwedder","year":"2016","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1055","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/s41398-018-0335-z","article-title":"Disruption of mTOR and MAPK pathways correlates with severity in idiopathic autism","volume":"9","author":"Rosina","year":"2019","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1060","doi-asserted-by":"crossref","first-page":"533","DOI":"10.2174\/1871527315666160413120638","article-title":"mTOR, a potential target to treat autism spectrum disorder","volume":"15","author":"Sato","year":"2016","journal-title":"CNS Neurol Disord: Drug Targets"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1065","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.ajhg.2012.03.017","article-title":"SHANK1 deletions in males with autism spectrum disorder","volume":"90","author":"Sato","year":"2012","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1070","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.cell.2019.12.036","article-title":"Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism","volume":"180","author":"Satterstrom","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1075","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/ncb996","article-title":"Rheb promotes cell growth as a component of the insulin\/TOR signalling network","volume":"5","author":"Saucedo","year":"2003","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1080","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0022-3476(61)80261-8","article-title":"Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded children","volume":"58","author":"Schain","year":"1961","journal-title":"J Pediatr"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1085","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0092-8674(00)80877-6","article-title":"Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons","volume":"101","author":"Scheiffele","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1090","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/S0896-6273(03)00354-4","article-title":"CYFIP\/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein","volume":"38","author":"Schenck","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1095","doi-asserted-by":"crossref","first-page":"8844","DOI":"10.1073\/pnas.151231598","article-title":"A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P","volume":"98","author":"Schenck","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1100","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.2174\/138161206777698909","article-title":"Serotonin and human cognitive performance","volume":"12","author":"Schmitt","year":"2006","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1105","doi-asserted-by":"crossref","first-page":"7936","DOI":"10.1523\/JNEUROSCI.4475-15.2016","article-title":"Circuit analysis of a Drosophila dopamine type 2 receptor that supports anesthesia-resistant memory","volume":"36","author":"Scholz-Kornehl","year":"2016","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1110","doi-asserted-by":"crossref","first-page":"10495","DOI":"10.1523\/JNEUROSCI.23-33-10495.2003","article-title":"Dopamine and octopamine differentiate between aversive and appetitive olfactory memories in Drosophila","volume":"23","author":"Schwaerzel","year":"2003","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1115","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.neulet.2006.11.062","article-title":"Major defects in neocortical GABAergic inhibitory circuits in mice lacking the fragile X mental retardation protein","volume":"412","author":"Selby","year":"2007","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1120","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.expneurol.2013.01.021","article-title":"Loss of GABAergic neurons in the hippocampus and cerebral cortex of Engrailed-2 null mutant mice: implications for autism spectrum disorders","volume":"247","author":"Sgad\u00f2","year":"2013","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1125","doi-asserted-by":"crossref","first-page":"18831","DOI":"10.1073\/pnas.1114569108","article-title":"Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila","volume":"108","author":"Shao","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1130","doi-asserted-by":"crossref","first-page":"11374","DOI":"10.1523\/JNEUROSCI.1163-15.2015","article-title":"Bidirectional regulation of amyloid precursor protein-induced memory defects by nebula\/DSCR1: A Protein upregulated in Alzheimer's disease and Down syndrome","volume":"35","author":"Shaw","year":"2015","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1135","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1126\/science.287.5459.1834","article-title":"Correlates of sleep and waking in Drosophila melanogaster","volume":"287","author":"Shaw","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1140","doi-asserted-by":"crossref","first-page":"3430","DOI":"10.1073\/pnas.76.7.3430","article-title":"Conditioned responses in courtship behavior of normal and mutant Drosophila","volume":"76","author":"Siegel","year":"1979","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1145","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1146\/annurev.neuro.21.1.127","article-title":"CREB and memory","volume":"21","author":"Silva","year":"1998","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1150","first-page":"73","article-title":"Control of sleep by dopaminergic inputs to the drosophila mushroom body","volume":"9","author":"Sitaraman","year":"2015","journal-title":"Front Neural Circuits"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1155","doi-asserted-by":"crossref","first-page":"5579","DOI":"10.1073\/pnas.0710168105","article-title":"Serotonin is necessary for place memory in Drosophila","volume":"105","author":"Sitaraman","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1160","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0074-7742(04)59006-2","article-title":"Serotonin and brain development","volume":"59","author":"Sodhi","year":"2004","journal-title":"Int Rev Neurobiol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1165","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1038\/35098592","article-title":"Drosophila: genetics meets behaviour","volume":"2","author":"Sokolowski","year":"2001","journal-title":"Nat Rev Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1170","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/nature12818","article-title":"CNVs conferring risk of autism or schizophrenia affect cognition in controls","volume":"505","author":"Stefansson","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1175","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/nature07229","article-title":"Large recurrent microdeletions associated with schizophrenia","volume":"455","author":"Stefansson","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1180","doi-asserted-by":"crossref","first-page":"9460","DOI":"10.1073\/pnas.1510103112","article-title":"What the fly's nose tells the fly's brain","volume":"112","author":"Stevens","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1185","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/cne.10285","article-title":"Organization of the honey bee mushroom body: representation of the calyx within the vertical and gamma lobes","volume":"450","author":"Strausfeld","year":"2002","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1190","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S0959-4388(99)00019-7","article-title":"Olfactory systems: common design, uncommon origins?","volume":"9","author":"Strausfeld","year":"1999","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1195","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1002\/(SICI)1096-9861(19990712)409:4<603::AID-CNE7>3.0.CO;2-P","article-title":"Organization of olfactory and multimodal afferent neurons supplying the calyx and pedunculus of the cockroach mushroom bodies","volume":"409","author":"Strausfeld","year":"1999","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1200","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1038\/nature07456","article-title":"Neuroligins and neurexins link synaptic function to cognitive disease","volume":"455","author":"S\u00fcdhof","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1205","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.cell.2017.10.024","article-title":"Synaptic neurexin complexes: A molecular code for the logic of neural circuits","volume":"171","author":"S\u00fcdhof","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1210","doi-asserted-by":"crossref","first-page":"3042","DOI":"10.1093\/hmg\/ddr208","article-title":"Identification and functional characterization of rare mutations of the neuroligin-2 gene (NLGN2) associated with schizophrenia","volume":"20","author":"Sun","year":"2011","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1215","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.neures.2009.04.009","article-title":"Genetic interaction between Neurexin and CAKI\/CMG is important for synaptic function in Drosophila neuromuscular junction","volume":"64","author":"Sun","year":"2009","journal-title":"Neurosci Res"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1220","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1523\/JNEUROSCI.3854-10.2011","article-title":"Neuroligin 2 is required for synapse development and function at the Drosophila neuromuscular junction","volume":"31","author":"Sun","year":"2011","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1225","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1086\/432648","article-title":"Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors","volume":"77","author":"Sutcliffe","year":"2005","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1230","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.26975","article-title":"A connectome of a learning and memory center in the adult Drosophila brain","volume":"6","author":"Takemura","year":"2017","journal-title":"Elife"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1235","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1042\/BST0380445","article-title":"Confirmed rare copy number variants implicate novel genes in schizophrenia","volume":"38","author":"Tam","year":"2010","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1240","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1002\/cne.21692","article-title":"Neuronal assemblies of the Drosophila mushroom body","volume":"508","author":"Tanaka","year":"2008","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1245","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1073\/pnas.80.5.1482","article-title":"Reward learning in normal and mutant Drosophila","volume":"80","author":"Tempel","year":"1983","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1250","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/978-3-642-21649-7_7","article-title":"Molecular and genetic analysis of the Drosophila model of fragile X syndrome","volume":"54","author":"Tessier","year":"2012","journal-title":"Results Probl Cell Differ"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1255","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1126\/science.276.5313.791","article-title":"Rescue of a Drosophila NF1 mutant phenotype by protein kinase A","volume":"276","author":"The","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1260","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/nn792","article-title":"Neurofibromin regulates G protein-stimulated adenylyl cyclase activity","volume":"5","author":"Tong","year":"2002","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1265","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3389\/fped.2017.00227","article-title":"Cognitive and behavioral disorders in children with neurofibromatosis type 1","volume":"5","author":"Torres Nupan","year":"2017","journal-title":"Front Pediatr"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1270","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.35264","article-title":"Drosophila mushroom bodies integrate hunger and satiety signals to control innate food-seeking behavior","volume":"7","author":"Tsao","year":"2018","journal-title":"Elife"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1275","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0092-8674(94)90398-0","article-title":"Genetic dissection of consolidated memory in Drosophila","volume":"79","author":"Tully","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1280","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/BF01350033","article-title":"Classical conditioning and retention in normal and mutant Drosophila melanogaster","volume":"157","author":"Tully","year":"1985","journal-title":"J Comp Physiol A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1285","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1242\/dmm.023762","article-title":"Drosophila tools and assays for the study of human diseases","volume":"9","author":"Ugur","year":"2016","journal-title":"Dis Model Mech"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1290","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.neubiorev.2014.01.013","article-title":"Drosophila models of early onset cognitive disorders and their clinical applications","volume":"46","author":"van der Voet","year":"2014","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1295","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1002\/ajmg.b.31055","article-title":"A co-segregating microduplication of chromosome 15q11.2 pinpoints two risk genes for autism spectrum disorder","volume":"153B","author":"van der Zwaag","year":"2010","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1300","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0124120","article-title":"Trends in the prevalence of autism spectrum disorder, cerebral palsy, hearing loss, intellectual disability, and vision impairment, metropolitan atlanta, 1991\u20132010","volume":"10","author":"Van Naarden Braun","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1305","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.ejmg.2015.01.002","article-title":"15q11.2 microdeletion (BP1-BP2) and developmental delay, behaviour issues, epilepsy and congenital heart disease: a series of 52 patients","volume":"58","author":"Vanlerberghe","year":"2015","journal-title":"Eur J Med Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1310","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.neuron.2006.09.003","article-title":"Neuroligins determine synapse maturation and function","volume":"51","author":"Varoqueaux","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1315","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/nmeth.1662","article-title":"MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes","volume":"8","author":"Venken","year":"2011","journal-title":"Nat Methods"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1320","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.neuron.2011.09.021","article-title":"Genetic manipulation of genes and cells in the nervous system of the fruit fly","volume":"72","author":"Venken","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1325","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/0092-8674(91)90397-H","article-title":"Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome","volume":"65","author":"Verkerk","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1330","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/978-3-7091-0932-8_2","article-title":"Scaffold proteins at the postsynaptic density","volume":"970","author":"Verpelli","year":"2012","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1335","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.02395","article-title":"Shared mushroom body circuits underlie visual and olfactory memories in Drosophila","volume":"3","author":"Vogt","year":"2014","journal-title":"Elife"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1340","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.nbd.2011.07.017","article-title":"Gene expression studies in autism: moving from the genome to the transcriptome and beyond","volume":"45","author":"Voineagu","year":"2012","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1345","article-title":"A Drosophila screen identifies neurofibromatosis-1 genetic modifiers involved in systemic and synaptic growth","volume":"2","author":"Walker","year":"2014","journal-title":"Rare Dis"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1350","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1007\/s00439-013-1416-y","article-title":"Common variants in genes of the postsynaptic FMRP signalling pathway are risk factors for autism spectrum disorders","volume":"133","author":"Waltes","year":"2014","journal-title":"Hum Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1355","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/aur.1881","article-title":"Neurexin gene family variants as risk factors for autism spectrum disorder","volume":"11","author":"Wang","year":"2018","journal-title":"Autism Res"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1360","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/ahg.12121","article-title":"Common Regulatory Variants of CYFIP1 Contribute to Susceptibility for Autism Spectrum Disorder (ASD) and Classical Autism","volume":"79","author":"Wang","year":"2015","journal-title":"Ann Hum Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1365","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/0378-1119(94)90396-4","article-title":"The Drosophila melanogaster ribosomal S6 kinase II-encoding sequence","volume":"144","author":"Wassarman","year":"1994","journal-title":"Gene"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1370","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/ajmg.a.31074","article-title":"Angelman syndrome 2005: updated consensus for diagnostic criteria","volume":"140","author":"Williams","year":"2006","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1375","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1038\/s41431-020-0626-8","article-title":"Association of congenital cardiovascular malformation and neuropsychiatric phenotypes with 15q11.2 (BP1-BP2) deletion in the UK Biobank","volume":"28","author":"Williams","year":"2020","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1380","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1038\/nrn1406","article-title":"Dopamine, learning and motivation","volume":"5","author":"Wise","year":"2004","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1385","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1101\/lm.5.1.166","article-title":"Drosophila mushroom bodies are dispensable for visual, tactile, and motor learning","volume":"5","author":"Wolf","year":"1998","journal-title":"Learn Mem"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1390","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.biopsych.2019.04.008","article-title":"Domain-specific cognitive impairments in humans and flies with reduced CYFIP1 dosage","volume":"86","author":"Woo","year":"2019","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1395","doi-asserted-by":"crossref","first-page":"11592","DOI":"10.1523\/JNEUROSCI.0893-17.2017","article-title":"A presynaptic function of shank protein in Drosophila","volume":"37","author":"Wu","year":"2017","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1400","doi-asserted-by":"crossref","first-page":"12399","DOI":"10.1073\/pnas.0805291105","article-title":"A Drosophila model for Angelman syndrome","volume":"105","author":"Wu","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1405","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1101\/lm.025726.112","article-title":"The GABAergic anterior paired lateral neurons facilitate olfactory reversal learning in Drosophila","volume":"19","author":"Wu","year":"2012","journal-title":"Learn Mem"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1410","unstructured":"Xu CS, Januszewski M, Lu Z, Takemura S-y, Hayworth KJ, Huang G, Shinomiya K, Maitin-Shepard J, et al. (2020), A connectome of the adult drosophila central brain. bioRxiv:2020.2001.2021.911859."},{"key":"10.1016\/j.neuroscience.2020.07.034_b1415","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1538\/expanim.63.107","article-title":"Dopamine dynamics and signaling in Drosophila: an overview of genes, drugs and behavioral paradigms","volume":"63","author":"Yamamoto","year":"2014","journal-title":"Exp Anim"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1420","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/j.cub.2006.04.032","article-title":"A sleep-promoting role for the Drosophila serotonin receptor 1A","volume":"16","author":"Yuan","year":"2006","journal-title":"Curr Biol"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1425","doi-asserted-by":"crossref","first-page":"2509","DOI":"10.1016\/j.febslet.2007.04.068","article-title":"Neurexin-1 is required for synapse formation and larvae associative learning in Drosophila","volume":"581","author":"Zeng","year":"2007","journal-title":"FEBS Lett"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1430","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.bbrc.2008.03.015","article-title":"Increased dopaminergic signaling impairs aversive olfactory memory retention in Drosophila","volume":"370","author":"Zhang","year":"2008","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1435","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1093\/schbul\/sbr197","article-title":"Rare CNVs and tag SNPs at 15q11.2 are associated with schizophrenia in the Han Chinese population","volume":"39","author":"Zhao","year":"2013","journal-title":"Schizophr Bull"},{"issue":"16","key":"10.1016\/j.neuroscience.2020.07.034_b1440","article-title":"Developmental phenotype in Phelan-McDermid (22q13.3 deletion) syndrome: a systematic and prospective study in 34 children","volume":"8","author":"Zwanenburg","year":"2016","journal-title":"J Neurodev Disord"},{"key":"10.1016\/j.neuroscience.2020.07.034_b1445","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.ajhg.2009.10.004","article-title":"CNTNAP2 and NRXN1 are mutated in autosomal-recessive Pitt-Hopkins-like mental retardation and determine the level of a common synaptic protein in Drosophila","volume":"85","author":"Zweier","year":"2009","journal-title":"Am J Hum Genet"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452220304772?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452220304772?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T15:58:23Z","timestamp":1759679903000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452220304772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":289,"alternative-id":["S0306452220304772"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2020.07.034","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Modelling Learning and Memory in Drosophila to Understand Intellectual Disabilities","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2020.07.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Ltd on behalf of IBRO.","name":"copyright","label":"Copyright"}]}}