{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T07:53:06Z","timestamp":1789026786043,"version":"build-2803163510"},"reference-count":83,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003792","name":"Hj\u00e4rnfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003792","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010815","name":"Stiftelsen f\u00f6r Gamla Tj\u00e4narinnor","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010815","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008599","name":"Alzheimerfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008599","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004063","name":"Knut och Alice Wallenbergs Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004063","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007416","name":"Swedish Brain Power","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007416","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009673","name":"Gun och Bertil Stohnes Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009673","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006285","name":"Magnus Bergvalls Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006285","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ibroneuroscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.neuroscience.2020.09.005","type":"journal-article","created":{"date-parts":[[2020,9,8]],"date-time":"2020-09-08T03:14:27Z","timestamp":1599534867000},"page":"14-27","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Chronic Airway Allergy Induces Pro-Inflammatory Responses in the Brain of Wildtype Mice but Not 3xTgAD Mice"],"prefix":"10.1016","volume":"448","author":[{"given":"Heela","family":"Sarlus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina","family":"Codita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuzhe","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angel","family":"Cedazo-Minguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Schultzberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mircea","family":"Oprica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.neuroscience.2020.09.005_b0005","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0889-8561(02)00048-6","article-title":"Immunologic and inflammatory mediators and cognitive decline in Alzheimer's disease","volume":"23","author":"Ahluwalia","year":"2003","journal-title":"Immunol Allergy Clin North Am"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0010","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.expneurol.2013.07.002","article-title":"Asthma: a clinical condition for brain health","volume":"248","author":"Alberi","year":"2013","journal-title":"Exp Neurol"},{"issue":"1","key":"10.1016\/j.neuroscience.2020.09.005_b0015","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/hipo.20356","article-title":"Differential involvement of the dorsal hippocampus in passive avoidance in C57bl\/6J and DBA\/2J mice","volume":"18","author":"Baarendse","year":"2008","journal-title":"Hippocampus"},{"issue":"6","key":"10.1016\/j.neuroscience.2020.09.005_b0020","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1016\/j.neurobiolaging.2014.01.003","article-title":"Migration of neutrophils targeting amyloid plaques in Alzheimer's disease mouse model","volume":"35","author":"Baik","year":"2014","journal-title":"Neurobiol Aging"},{"issue":"1\u20132","key":"10.1016\/j.neuroscience.2020.09.005_b0025","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0165-5728(03)00166-8","article-title":"Neural correlates of IgE-mediated food allergy","volume":"140","author":"Basso","year":"2003","journal-title":"J Neuroimmunol"},{"issue":"2","key":"10.1016\/j.neuroscience.2020.09.005_b0030","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0031-9384(73)90296-5","article-title":"Effects of hippocampal lesions on passive avoidance and taste aversion conditioning","volume":"10","author":"Best","year":"1973","journal-title":"Physiol Behav"},{"issue":"2","key":"10.1016\/j.neuroscience.2020.09.005_b0035","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.pharmthera.2013.12.009","article-title":"Genetic mouse models of brain ageing and Alzheimer's disease","volume":"142","author":"Bilkei-Gorzo","year":"2014","journal-title":"Pharmacol Ther"},{"issue":"5","key":"10.1016\/j.neuroscience.2020.09.005_b0040","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.neuron.2005.01.040","article-title":"Intraneuronal A\u03b2 causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice","volume":"45","author":"Billings","year":"2005","journal-title":"Neuron"},{"issue":"2","key":"10.1016\/j.neuroscience.2020.09.005_b0045","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1007\/s12035-014-8657-1","article-title":"Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview","volume":"50","author":"Brosseron","year":"2014","journal-title":"Mol Neurobiol"},{"issue":"12","key":"10.1016\/j.neuroscience.2020.09.005_b0050","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1111\/ene.12477","article-title":"A study on the association between infectious burden and Alzheimer's disease","volume":"22","author":"Bu","year":"2015","journal-title":"Eur J Neurol"},{"issue":"4","key":"10.1016\/j.neuroscience.2020.09.005_b0055","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/all.12125","article-title":"Relationship between asthma and cognition: the Cooper Center Longitudinal Study","volume":"68","author":"Caldera-Alvarado","year":"2013","journal-title":"Allergy"},{"issue":"1","key":"10.1016\/j.neuroscience.2020.09.005_b0060","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1017\/S1461145711000149","article-title":"Increased NF-kB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease","volume":"15","author":"Chen","year":"2012","journal-title":"Int J Neuropsychopharmacol"},{"issue":"1","key":"10.1016\/j.neuroscience.2020.09.005_b0065","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.nbd.2007.06.013","article-title":"Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice","volume":"28","author":"Clinton","year":"2007","journal-title":"Neurobiol Dis"},{"issue":"4","key":"10.1016\/j.neuroscience.2020.09.005_b0070","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.biopsych.2008.07.024","article-title":"Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease","volume":"65","author":"Cunningham","year":"2009","journal-title":"Biol Psychiatry"},{"issue":"1","key":"10.1016\/j.neuroscience.2020.09.005_b0075","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1038\/nprot.2006.19","article-title":"Burrowing in rodents: a sensitive method for detecting behavioral dysfunction","volume":"1","author":"Deacon","year":"2006","journal-title":"Nat Protoc"},{"issue":"2\u20133","key":"10.1016\/j.neuroscience.2020.09.005_b0080","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00685397","article-title":"Immunoglobulins and complement factors in senile plaques. An immunoperoxidase study","volume":"57","author":"Eikelenboom","year":"1982","journal-title":"Acta Neuropathol"},{"issue":"5\u20136","key":"10.1016\/j.neuroscience.2020.09.005_b0085","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/FBP.0b013e3282de7929","article-title":"The role of hippocampus in anxiety: intracerebral infusion studies","volume":"18","author":"Engin","year":"2007","journal-title":"Behav Pharmacol"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0090","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1159\/000112729","article-title":"Asthma, eczema, rhinitis and the risk for dementia","volume":"25","author":"Eriksson","year":"2008","journal-title":"Dement Geriatr Cogn Disord"},{"issue":"6","key":"10.1016\/j.neuroscience.2020.09.005_b0095","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.biopsych.2009.06.015","article-title":"Intraneuronal \u03b2-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice","volume":"67","author":"Espana","year":"2010","journal-title":"Biol Psychiatry"},{"issue":"2","key":"10.1016\/j.neuroscience.2020.09.005_b0100","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.bbr.2012.07.004","article-title":"Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer's disease expressing mutated APP, PS1, and Mapt (3xTg-AD)","volume":"234","author":"Filali","year":"2012","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0105","unstructured":"File SE, Lippa AS, Beer B, Lippa MT (2005) Animal tests of anxiety. Curr Protoc Pharmacol Chapter 5: Unit 5 38."},{"key":"10.1016\/j.neuroscience.2020.09.005_b0110","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1093\/emph\/eot015","article-title":"Andrews PW Fincher CL (2013) Hygiene and the world distribution of Alzheimer's disease: Epidemiological evidence for a relationship between microbial environment and age-adjusted disease burden","volume":"1","author":"Fox","year":"2013","journal-title":"Evol Med Public Health"},{"issue":"4\u20135","key":"10.1016\/j.neuroscience.2020.09.005_b0115","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.imbio.2006.11.001","article-title":"C1q and its growing family","volume":"212","author":"Ghai","year":"2007","journal-title":"Immunobiology"},{"issue":"1","key":"10.1016\/j.neuroscience.2020.09.005_b0120","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.neubiorev.2006.07.007","article-title":"Modeling behavioral and neuronal symptoms of Alzheimer's disease in mice: a role for intraneuronal amyloid","volume":"31","author":"Gimenez-Llort","year":"2007","journal-title":"Neurosci Biobehav Rev"},{"issue":"12","key":"10.1016\/j.neuroscience.2020.09.005_b0125","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1007\/s00011-009-0054-2","article-title":"Mouse models of asthma: a comparison between C57BL\/6 and BALB\/c strains regarding bronchial responsiveness, inflammation, and cytokine production","volume":"58","author":"Gueders","year":"2009","journal-title":"Inflamm Res"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0130","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.expneurol.2013.04.008","article-title":"Chronic asthma results in cognitive dysfunction in immature mice","volume":"247","author":"Guo","year":"2013","journal-title":"Exp Neurol"},{"issue":"2","key":"10.1016\/j.neuroscience.2020.09.005_b0135","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1007\/s11481-007-9069-z","article-title":"Microglial activation is required for A\u03b2 clearance after intracranial injection of lipopolysaccharide in APP transgenic mice","volume":"2","author":"Herber","year":"2007","journal-title":"J Neuroimmune Pharmacol"},{"issue":"10","key":"10.1016\/j.neuroscience.2020.09.005_b0140","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1212\/WNL.0b013e3181b6bb95","article-title":"Systemic inflammation and disease progression in Alzheimer disease","volume":"73","author":"Holmes","year":"2009","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.neuroscience.2020.09.005_b0145","doi-asserted-by":"crossref","first-page":"361","DOI":"10.3233\/JAD-2011-110608","article-title":"Biochemical and morphological characterization of the A\u03b2PP\/PS\/tau triple transgenic mouse model and its relevance to sporadic Alzheimer's disease","volume":"27","author":"Hunter","year":"2011","journal-title":"J Alzheimers Dis"},{"issue":"10","key":"10.1016\/j.neuroscience.2020.09.005_b0150","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1080\/13803395.2017.1288802","article-title":"Is asthma associated with cognitive impairments? A meta-analytic review","volume":"39","author":"Irani","year":"2017","journal-title":"J Clin Exp Neuropsychol"},{"issue":"3","key":"10.1016\/j.neuroscience.2020.09.005_b0155","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/0006-8993(78)90820-X","article-title":"The influence of brain damage on locomotor behavior of mice selectively bred for high or low activity in the open field","volume":"150","author":"Isaacson","year":"1978","journal-title":"Brain Res"},{"issue":"6","key":"10.1016\/j.neuroscience.2020.09.005_b0160","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1067\/mai.2002.129371","article-title":"CpG-oligodeoxynucleotides inhibit airway remodeling in a murine model of chronic asthma","volume":"110","author":"Jain","year":"2002","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0165","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1742-2094-2-23","article-title":"Early correlation of microglial activation with enhanced tumor necrosis factor-\u03b1 and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice","volume":"2","author":"Janelsins","year":"2005","journal-title":"J Neuroinflammation"},{"issue":"3","key":"10.1016\/j.neuroscience.2020.09.005_b0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0033312","article-title":"Toxoplasma gondii infection in the brain inhibits neuronal degeneration and learning and memory impairments in a murine model of Alzheimer's disease","volume":"7","author":"Jung","year":"2012","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.neuroscience.2020.09.005_b0175","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1165\/rcmb.2010-0315OC","article-title":"Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice","volume":"45","author":"Kelada","year":"2011","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"39","key":"10.1016\/j.neuroscience.2020.09.005_b0180","doi-asserted-by":"crossref","first-page":"8843","DOI":"10.1523\/JNEUROSCI.2868-05.2005","article-title":"Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease","volume":"25","author":"Kitazawa","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0185","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3389\/fncel.2016.00169","article-title":"Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus","volume":"10","author":"Klein","year":"2016","journal-title":"Front Cell Neurosci"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0190","doi-asserted-by":"crossref","first-page":"312","DOI":"10.3389\/fphys.2012.00312","article-title":"Are mouse models of asthma appropriate for investigating the pathogenesis of airway hyper-responsiveness?","volume":"3","author":"Kumar","year":"2012","journal-title":"Front Physiol"},{"issue":"6","key":"10.1016\/j.neuroscience.2020.09.005_b0195","doi-asserted-by":"crossref","first-page":"485","DOI":"10.2174\/138945008784533561","article-title":"The \u201cclassical\u201d ovalbumin challenge model of asthma in mice","volume":"9","author":"Kumar","year":"2008","journal-title":"Curr Drug Targets"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0200","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/1742-2094-7-56","article-title":"LPS-induced inflammation exacerbates phospho-tau pathology in rTg4510 mice","volume":"7","author":"Lee","year":"2010","journal-title":"J Neuroinflammation"},{"issue":"3","key":"10.1016\/j.neuroscience.2020.09.005_b0205","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1128\/IAI.01172-13","article-title":"Eosinophil deficiency compromises lung defense against Aspergillus fumigatus","volume":"82","author":"Lilly","year":"2014","journal-title":"Infect Immun"},{"issue":"4","key":"10.1016\/j.neuroscience.2020.09.005_b0210","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.jaci.2008.02.004","article-title":"Cell-specific activation profile of extracellular signal-regulated kinase 1\/2, Jun N-terminal kinase, and p38 mitogen-activated protein kinases in asthmatic airways","volume":"121","author":"Liu","year":"2008","journal-title":"J Allergy Clin Immunol"},{"issue":"10","key":"10.1016\/j.neuroscience.2020.09.005_b0215","doi-asserted-by":"crossref","first-page":"2774","DOI":"10.1172\/JCI25420","article-title":"A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease","volume":"115","author":"Lukiw","year":"2005","journal-title":"J Clin Invest"},{"issue":"2","key":"10.1016\/j.neuroscience.2020.09.005_b0220","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1128\/IAI.70.2.427-433.2002","article-title":"Immunology of parasitic helminth infections","volume":"70","author":"MacDonald","year":"2002","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.neuroscience.2020.09.005_b0225","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1136\/thx.48.1.79","article-title":"New perspectives on basic mechanisms in lung disease. 2. Neutrophil traffic in the lungs: role of haemodynamics, cell adhesion, and deformability","volume":"48","author":"MacNee","year":"1993","journal-title":"Thorax"},{"issue":"1","key":"10.1016\/j.neuroscience.2020.09.005_b0230","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3233\/JAD-131490","article-title":"Autoimmune manifestations in the 3xTg-AD model of Alzheimer's disease","volume":"39","author":"Marchese","year":"2014","journal-title":"J Alzheimers Dis"},{"issue":"5","key":"10.1016\/j.neuroscience.2020.09.005_b0235","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1398-9995.2004.00526.x","article-title":"The global burden of asthma: executive summary of the GINA Dissemination Committee report","volume":"59","author":"Masoli","year":"2004","journal-title":"Allergy"},{"issue":"4","key":"10.1016\/j.neuroscience.2020.09.005_b0240","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1042\/CS20140373","article-title":"Translational models of lung disease","volume":"128","author":"Mercer","year":"2015","journal-title":"Clin Sci (Lond)"},{"issue":"5","key":"10.1016\/j.neuroscience.2020.09.005_b0245","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.4049\/jimmunol.172.5.2731","article-title":"Of mice and not men: differences between mouse and human immunology","volume":"172","author":"Mestas","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0250","article-title":"Neural pathways in allergic inflammation","volume":"2010","author":"Mirotti","year":"2010","journal-title":"J Allergy (Cairo)"},{"issue":"11","key":"10.1016\/j.neuroscience.2020.09.005_b0255","doi-asserted-by":"crossref","first-page":"3151","DOI":"10.1084\/jem.20171406","article-title":"Alzheimer's disease: A matter of blood-brain barrier dysfunction?","volume":"214","author":"Montagne","year":"2017","journal-title":"J Exp Med"},{"issue":"6","key":"10.1016\/j.neuroscience.2020.09.005_b0260","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1378\/chest.09-1895","article-title":"Recent advances in the pathophysiology of asthma","volume":"137","author":"Murphy","year":"2010","journal-title":"Chest"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0265","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/j.neurobiolaging.2003.08.012","article-title":"Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease","volume":"24","author":"Oddo","year":"2003","journal-title":"Neurobiol Aging"},{"issue":"3","key":"10.1016\/j.neuroscience.2020.09.005_b0270","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0896-6273(03)00434-3","article-title":"Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular A\u03b2 and synaptic dysfunction","volume":"39","author":"Oddo","year":"2003","journal-title":"Neuron"},{"issue":"2 Pt 1","key":"10.1016\/j.neuroscience.2020.09.005_b0275","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1164\/ajrccm.161.2.9902094","article-title":"Prolonged allergen exposure induces structural airway changes in sensitized rats","volume":"161","author":"Palmans","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.neuroscience.2020.09.005_b0280","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0091-3057(95)00138-M","article-title":"Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety","volume":"52","author":"Rodgers","year":"1995","journal-title":"Pharmacol Biochem Behav"},{"issue":"Pt 3","key":"10.1016\/j.neuroscience.2020.09.005_b0285","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1093\/brain\/awv404","article-title":"Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer's disease","volume":"139","author":"Rodriguez-Vieitez","year":"2016","journal-title":"Brain"},{"issue":"8","key":"10.1016\/j.neuroscience.2020.09.005_b0290","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0040921","article-title":"Are there neurophenotypes for asthma? Functional brain imaging of the interaction between emotion and inflammation in asthma","volume":"7","author":"Rosenkranz","year":"2012","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.neuroscience.2020.09.005_b0295","doi-asserted-by":"crossref","first-page":"549","DOI":"10.2174\/1567205011310050011","article-title":"Chronic obstructive pulmonary disease and asthma and the risk of mild cognitive impairment and dementia: a population based CAIDE study","volume":"10","author":"Rusanen","year":"2013","journal-title":"Curr Alzheimer Res"},{"issue":"9","key":"10.1016\/j.neuroscience.2020.09.005_b0300","doi-asserted-by":"crossref","first-page":"3240","DOI":"10.1172\/JCI90606","article-title":"Microglia in Alzheimer's disease","volume":"127","author":"Sarlus","year":"2017","journal-title":"J Clin Invest"},{"issue":"10","key":"10.1016\/j.neuroscience.2020.09.005_b0305","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1111\/j.1582-4934.2012.01556.x","article-title":"Allergy influences the inflammatory status of the brain and enhances tau-phosphorylation","volume":"16","author":"Sarlus","year":"2012","journal-title":"J Cell Mol Med"},{"issue":"10","key":"10.1016\/j.neuroscience.2020.09.005_b0310","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1111\/j.1582-4934.2012.01556.x","article-title":"Allergy influences the inflammatory status of the brain and enhances tau-phosphorylation","volume":"16","author":"Sarlus","year":"2012","journal-title":"J Cell Mol Med"},{"issue":"1","key":"10.1016\/j.neuroscience.2020.09.005_b0315","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/1742-2094-10-99","article-title":"Chronic airway-induced allergy in mice modifies gene expression in the brain toward insulin resistance and inflammatory responses","volume":"10","author":"Sarlus","year":"2013","journal-title":"J Neuroinflammation"},{"issue":"1","key":"10.1016\/j.neuroscience.2020.09.005_b0320","doi-asserted-by":"crossref","first-page":"3261","DOI":"10.1038\/s41467-018-05800-6","article-title":"Resolution of chronic inflammatory disease: universal and tissue-specific concepts","volume":"9","author":"Schett","year":"2018","journal-title":"Nat Commun"},{"issue":"2","key":"10.1016\/j.neuroscience.2020.09.005_b0325","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1096\/fj.06-7227rev","article-title":"Resolution of inflammation: state of the art, definitions and terms","volume":"21","author":"Serhan","year":"2007","journal-title":"FASEB J"},{"issue":"8","key":"10.1016\/j.neuroscience.2020.09.005_b0330","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1002\/syn.21651","article-title":"Peripheral markers of Alzheimer's disease: surveillance of white blood cells","volume":"67","author":"Shad","year":"2013","journal-title":"Synapse"},{"issue":"1","key":"10.1016\/j.neuroscience.2020.09.005_b0335","doi-asserted-by":"crossref","first-page":"10","DOI":"10.4168\/aair.2009.1.1.10","article-title":"Understanding asthma using animal models","volume":"1","author":"Shin","year":"2009","journal-title":"Allergy Asthma Immunol Res"},{"issue":"12","key":"10.1016\/j.neuroscience.2020.09.005_b0340","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1038\/jcbfm.2013.160","article-title":"Brain bioavailability of human intravenous immunoglobulin and its transport through the murine blood-brain barrier","volume":"33","author":"St-Amour","year":"2013","journal-title":"J Cereb Blood Flow Metab"},{"issue":"2","key":"10.1016\/j.neuroscience.2020.09.005_b0345","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1177\/0269881107073199","article-title":"The Open Field Test: reinventing the wheel","volume":"21","author":"Stanford","year":"2007","journal-title":"J Psychopharmacol"},{"issue":"33","key":"10.1016\/j.neuroscience.2020.09.005_b0350","doi-asserted-by":"crossref","first-page":"13460","DOI":"10.1523\/JNEUROSCI.1333-13.2013","article-title":"A dramatic increase of C1q protein in the CNS during normal aging","volume":"33","author":"Stephan","year":"2013","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0355","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.brainres.2010.06.011","article-title":"Characterization of the 3xTg-AD mouse model of Alzheimer's disease: part 2. Behavioral and cognitive changes","volume":"1348","author":"Sterniczuk","year":"2010","journal-title":"Brain Res"},{"issue":"10","key":"10.1016\/j.neuroscience.2020.09.005_b0360","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.biopsych.2010.06.012","article-title":"A meta-analysis of cytokines in Alzheimer's disease","volume":"68","author":"Swardfager","year":"2010","journal-title":"Biol Psychiatry"},{"issue":"5","key":"10.1016\/j.neuroscience.2020.09.005_b0365","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1538\/expanim1978.43.5_697","article-title":"Age-related memory impairment and hippocampal damage in ddY male mice","volume":"43","author":"Tanaka","year":"1995","journal-title":"Exp Anim"},{"issue":"6","key":"10.1016\/j.neuroscience.2020.09.005_b0370","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/j.bbi.2007.01.012","article-title":"Sub-pyrogenic systemic inflammation impacts on brain and behavior, independent of cytokines","volume":"21","author":"Teeling","year":"2007","journal-title":"Brain Behav Immun"},{"issue":"6","key":"10.1016\/j.neuroscience.2020.09.005_b0375","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.bbi.2009.02.017","article-title":"Allergic rhinitis induces anxiety-like behavior and altered social interaction in rodents","volume":"23","author":"Tonelli","year":"2009","journal-title":"Brain Behav Immun"},{"issue":"4","key":"10.1016\/j.neuroscience.2020.09.005_b0380","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.4049\/jimmunol.174.4.2353","article-title":"Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation","volume":"174","author":"van Beek","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0385","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jalz.2013.12.024","article-title":"Resolution of inflammation is altered in Alzheimer's disease","volume":"11","author":"Wang","year":"2015","journal-title":"Alzheimers Dementia"},{"issue":"1","key":"10.1016\/j.neuroscience.2020.09.005_b0390","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a006346","article-title":"Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature","volume":"2","author":"Wyss-Coray","year":"2012","journal-title":"Cold Spring Harb Perspect Med"},{"issue":"2","key":"10.1016\/j.neuroscience.2020.09.005_b0395","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1164\/ajrccm.155.2.9032210","article-title":"Influence of the route of allergen administration and genetic background on the murine allergic pulmonary response","volume":"155","author":"Zhang","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.neuroscience.2020.09.005_b0400","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.bbr.2018.01.011","article-title":"Food allergy induces alteration in brain inflammatory status and cognitive impairments","volume":"364","author":"Zhou","year":"2019","journal-title":"Behav Brain Res"},{"issue":"4","key":"10.1016\/j.neuroscience.2020.09.005_b0405","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1007\/s12035-015-9544-0","article-title":"Pro-resolving lipid mediators improve neuronal survival and increase A\u03b242 phagocytosis","volume":"53","author":"Zhu","year":"2016","journal-title":"Mol Neurobiol"},{"issue":"3","key":"10.1016\/j.neuroscience.2020.09.005_b0410","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s00251-008-0353-8","article-title":"Comparison of allergic lung disease in three mouse strains after systemic or mucosal sensitization with ovalbumin antigen","volume":"61","author":"Zhu","year":"2009","journal-title":"Immunogenetics"},{"issue":"3","key":"10.1016\/j.neuroscience.2020.09.005_b0415","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0014-4886(90)90144-H","article-title":"A saturable mechanism for transport of immunoglobulin G across the blood-brain barrier of the guinea pig","volume":"107","author":"Zlokovic","year":"1990","journal-title":"Exp Neurol"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452220305704?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452220305704?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T15:59:31Z","timestamp":1759679971000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452220305704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":83,"alternative-id":["S0306452220305704"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2020.09.005","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chronic Airway Allergy Induces Pro-Inflammatory Responses in the Brain of Wildtype Mice but Not 3xTgAD Mice","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2020.09.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier Ltd on behalf of IBRO.","name":"copyright","label":"Copyright"}]}}