{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T16:42:32Z","timestamp":1759682552867,"version":"build-2065373602"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T00:00:00Z","timestamp":1605052800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000262","name":"Foundation Fighting Blindness","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000262","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ibroneuroscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.neuroscience.2020.10.030","type":"journal-article","created":{"date-parts":[[2020,11,14]],"date-time":"2020-11-14T07:40:54Z","timestamp":1605339654000},"page":"169-180","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Sensory Experience Modulates Atrx-mediated Neuronal Integrity in the Mouse Retina"],"prefix":"10.1016","volume":"452","author":[{"given":"Pamela S.","family":"Lagali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon Y.H.","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keqin","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam N.","family":"Baker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart G.","family":"Coupland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Tsilfidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Picketts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2020.10.030_b0005","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1186\/s12864-015-1787-7","article-title":"Identification and functional analysis of early gene expression induced by circadian light-resetting in Drosophila","volume":"16","author":"Adewoye","year":"2015","journal-title":"BMC Genomics"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0010","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0165-0270(91)90016-S","article-title":"Application of a fluorometric method to measure glutamate release from single retinal photoreceptors","volume":"37","author":"Ayoub","year":"1991","journal-title":"J Neurosci Methods"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0015","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1172\/JCI200522329","article-title":"The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis","volume":"115","author":"B\u00e9rub\u00e9","year":"2005","journal-title":"J Clin Invest"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0020","doi-asserted-by":"crossref","first-page":"E2836","DOI":"10.1073\/pnas.1503512112","article-title":"Light signaling controls nuclear architecture reorganization during seedling establishment","volume":"112","author":"Bourbousse","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0025","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.visres.2006.11.020","article-title":"Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene","volume":"47","author":"Chang","year":"2007","journal-title":"Vision Res"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0030","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.neulet.2006.06.042","article-title":"Expression of nicotinamide adenine dinucleotide phosphate-diaphorase in the retina of postnatal golden hamsters deprived of light stimulation","volume":"405","author":"Chen","year":"2006","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.preteyeres.2018.03.002","article-title":"Epigenetic control of gene regulation during development and disease: A view from the retina","volume":"65","author":"Corso-D\u00edaz","year":"2018","journal-title":"Progr Retin Eye Res"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0040","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/978-1-4614-0631-0_18","article-title":"Dark-rearing the rd10 mouse: implications for therapy","volume":"723","author":"Cronin","year":"2012","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0045","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1038\/81767","article-title":"Light induces chromatin modification in cells of the mammalian circadian clock","volume":"3","author":"Crosio","year":"2000","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0050","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1167\/iovs.14-15479","article-title":"Genetic background and light-dependent progression of photoreceptor cell degeneration in prominin-1 knockout mice","volume":"56","author":"Dellett","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev-vision-102016-061345","article-title":"Inhibitory interneurons in the retina: types, circuitry, and function","volume":"3","author":"Diamond","year":"2017","journal-title":"Annu Rev Vis Sci"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0060","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.neuron.2013.09.024","article-title":"Sensory experience shapes the development of the visual system\u2019s first synapse","volume":"80","author":"Dunn","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0065","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1167\/iovs.09-4438","article-title":"Experience-dependent regulation of NMDA receptor subunit composition and phosphorylation in the retina and visual cortex","volume":"51","author":"Giannakopoulos","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0070","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.bbrc.2007.10.204","article-title":"Long-term dark rearing induces permanent reorganization in retinal circuitry","volume":"365","author":"Giovannelli","year":"2008","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0075","first-page":"4787","article-title":"Retinal interneuron survival requires non-cell-autonomous Atrx activity","volume":"25","author":"Lagali","year":"2016","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0080","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s12177-012-9080-3","article-title":"Matters of life and death: the role of chromatin remodeling proteins in retinal neuron survival","volume":"4","author":"Lagali","year":"2011","journal-title":"J Ocul Biol Dis Inf"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0085","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1111\/j.1460-9568.2006.05078.x","article-title":"Dark-rearing-induced reduction of GABA and GAD and prevention of the effect by BDNF in the mouse retina","volume":"24","author":"Lee","year":"2006","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0090","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1007\/s003359900594","article-title":"Allele-specific PCR assays for the tub and cpefat mutations","volume":"8","author":"Maddatu","year":"1997","journal-title":"Mamm Genome"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0095","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1007\/s11064-011-0467-5","article-title":"Age and visual experience-dependent expression of NMDAR1 splice variants in rat retina","volume":"36","author":"Manta","year":"2011","journal-title":"Neurochem Res"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0100","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/0092-8674(95)90354-2","article-title":"Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene","volume":"80","author":"Masu","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0105","doi-asserted-by":"crossref","first-page":"4385","DOI":"10.1113\/jphysiol.2008.159327","article-title":"Comparisons of structural and functional abnormalities in mouse b-wave mutants","volume":"586","author":"McCall","year":"2008","journal-title":"J Physiol"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0110","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1093\/hmg\/ddn424","article-title":"Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome","volume":"18","author":"Medina","year":"2009","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0115","doi-asserted-by":"crossref","first-page":"11868","DOI":"10.1016\/S0021-9258(19)50280-0","article-title":"Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate","volume":"268","author":"Nakajima","year":"1993","journal-title":"J Biol Chem"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0120","series-title":"Webvision: the organization of the retina and visual system","article-title":"Bipolar cell pathways in the vertebrate retina","author":"Nelson","year":"1995"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0125","doi-asserted-by":"crossref","first-page":"6820","DOI":"10.1073\/pnas.1411258112","article-title":"ATRX tolerates activity-dependent histone H3 methyl\/phos switching to maintain repetitive element silencing in neurons","volume":"112","author":"Noh","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0130","doi-asserted-by":"crossref","first-page":"4278","DOI":"10.1167\/iovs.07-1622","article-title":"AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation","volume":"49","author":"Pang","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0135","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1111\/nph.14269","article-title":"Light behind the curtain: photoregulation of nuclear architecture and chromatin dynamics in plants","volume":"212","author":"Perrella","year":"2016","journal-title":"New Phytol"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0140","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1017\/S0952523807070149","article-title":"Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse","volume":"24","author":"Pinto","year":"2007","journal-title":"Vis Neurosci"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0145","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.ydbio.2004.03.039","article-title":"Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter","volume":"271","author":"Rowan","year":"2004","journal-title":"Dev Biol"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0150","doi-asserted-by":"crossref","first-page":"9043","DOI":"10.1523\/JNEUROSCI.2245-07.2007","article-title":"Dark rearing rescues P23H rhodopsin-induced retinal degeneration in a transgenic Xenopus laevis model of retinitis pigmentosa: a chromophore-dependent mechanism characterized by production of N-terminally truncated mutant rhodopsin","volume":"27","author":"Tam","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0155","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0896-6273(03)00389-1","article-title":"Visual stimulation is required for refinement of ON and OFF pathways in postnatal retina","volume":"39","author":"Tian","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0160","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/S0896-6273(01)00470-6","article-title":"Visual deprivation alters development of synaptic function in inner retina after eye opening","volume":"32","author":"Tian","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0165","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/ejn.12783","article-title":"Dopamine D2 receptors preferentially regulate the development of light responses of the inner retina","volume":"41","author":"Tian","year":"2015","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0170","doi-asserted-by":"crossref","first-page":"6261","DOI":"10.1523\/JNEUROSCI.5646-06.2007","article-title":"A novel connection between rods and ON cone bipolar cells revealed by ectopic metabotropic glutamate receptor 7 (mGluR7) in mGluR6-deficient mouse retinas","volume":"27","author":"Tsukamoto","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0175","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1016\/j.celrep.2018.04.086","article-title":"Melanopsin retinal ganglion cells regulate cone photoreceptor lamination in the mouse retina","volume":"23","author":"Tufford","year":"2018","journal-title":"Cell Reports"},{"issue":"1","key":"10.1016\/j.neuroscience.2020.10.030_b0180","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1017\/S0952523804041033","article-title":"Light deprivation suppresses the light response of inner retina in both young and adult mouse","volume":"21","author":"Vistamehr","year":"2004","journal-title":"Vis Neurosci"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0185","first-page":"18","article-title":"Dark rearing maintains tyrosine hydroxylase expression in retinal amacrine cells following optic nerve transection","volume":"7","author":"Wan","year":"2012","journal-title":"Neural Regen Res"},{"key":"10.1016\/j.neuroscience.2020.10.030_b0190","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1002\/cne.20470","article-title":"Development of cholinergic amacrine cells is visual activity-dependent in the postnatal mouse retina","volume":"484","author":"Zhang","year":"2005","journal-title":"J Comp Neurol"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452220306977?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452220306977?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T16:02:22Z","timestamp":1759680142000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452220306977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":38,"alternative-id":["S0306452220306977"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2020.10.030","relation":{},"ISSN":["0306-4522"],"issn-type":[{"type":"print","value":"0306-4522"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sensory Experience Modulates Atrx-mediated Neuronal Integrity in the Mouse Retina","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2020.10.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Author(s). Published by Elsevier Ltd on behalf of IBRO.","name":"copyright","label":"Copyright"}]}}