{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T05:39:50Z","timestamp":1785649190917,"version":"3.56.0"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ibroneuroscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.neuroscience.2023.01.004","type":"journal-article","created":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T11:31:25Z","timestamp":1673263885000},"page":"137-144","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Brain Functional Alterations and Association with Cognition in People with Preclinical Subjective Cognitive Decline and Objective Subtle Cognitive Difficulties"],"prefix":"10.1016","volume":"513","author":[{"given":"Shuhua","family":"Ren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junpeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kewei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingchao","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Jessen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaochen","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donglang","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihui","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengchun","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qihao","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2023.01.004_b0005","doi-asserted-by":"crossref","first-page":"5768","DOI":"10.1088\/0031-9155\/61\/15\/5768","article-title":"Automated PET-only quantification of amyloid deposition with adaptive template and empirically pre-defined ROI","volume":"61","author":"Akamatsu","year":"2016","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0010","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.neuron.2005.04.034","article-title":"The neuroanatomy of remote memory","volume":"46","author":"Bayley","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0015","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1001\/jamaneurol.2017.2216","article-title":"Region-Specific Association of Subjective Cognitive Decline With Tauopathy Independent of Global \u03b2-Amyloid Burden","volume":"74","author":"Buckley","year":"2017","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0020","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1177\/0891988710363715","article-title":"Pittsburgh compound B (11C-PIB) and fluorodeoxyglucose (18 F-FDG) PET in patients with Alzheimer disease, mild cognitive impairment, and healthy controls","volume":"23","author":"Devanand","year":"2010","journal-title":"J Geriatr Psychiatry Neurol"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0025","first-page":"28","article-title":"Progression and predictors of mild cognitive impairment in Chinese elderly: A prospective follow-up in the Shanghai Aging Study","volume":"4","author":"Ding","year":"2016","journal-title":"Alzheimer's Dementia: Diagnosis, Assess Disease Monitor"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0030","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1017\/S135561771400068X","article-title":"Subjective cognitive complaints contribute to misdiagnosis of mild cognitive impairment","volume":"20","author":"Edmonds","year":"2014","journal-title":"J Int Neuropsychol Soc"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0035","doi-asserted-by":"crossref","first-page":"231","DOI":"10.3233\/JAD-150128","article-title":"Subtle Cognitive Decline and Biomarker Staging in Preclinical Alzheimer\u2019s Disease","volume":"47","author":"Edmonds","year":"2015","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0040","doi-asserted-by":"crossref","first-page":"e00776","DOI":"10.1002\/brb3.776","article-title":"Biomarkers in subtypes of mild cognitive impairment and subjective cognitive decline","volume":"7","author":"Eliassen","year":"2017","journal-title":"Brain Behav"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0045","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.neuroimage.2016.02.042","article-title":"Different partial volume correction methods lead to different conclusions: An F-18-FDG-PET study of aging","volume":"132","author":"Greve","year":"2016","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0050","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/WAD.0b013e3181999e92","article-title":"A Comparison Study of Mild Cognitive Impairment With 3 Memory Tests Among Chinese Individuals","volume":"23","author":"Guo","year":"2009","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0055","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1176\/jnp.12.1.25","article-title":"Occipital atrophy is associated with visual hallucinations in Alzheimer's disease","volume":"12","author":"Holroyd","year":"2000","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0060","doi-asserted-by":"crossref","first-page":"517","DOI":"10.2174\/1567205017666200807193253","article-title":"A Conceptual Framework for Research on Cognitive Impairment with no Dementia in Memory Clinic","volume":"17","author":"Huang","year":"2020","journal-title":"Curr Alzheimer Res"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0065","first-page":"1","article-title":"Changes in brain glucose metabolism and connectivity in somatoform disorders: an (18)F-FDG PET study","author":"Huang","year":"2019","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0070","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/S1474-4422(14)70194-2","article-title":"Age-specific population frequencies of cerebral \u03b2-amyloidosis and neurodegeneration among people with normal cognitive function aged 50\u201389 years: a cross-sectional study","volume":"13","author":"Jack","year":"2014","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0075","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1212\/WNL.0000000000002923","article-title":"A\/T\/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers","volume":"87","author":"Jack","year":"2016","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0080","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.jalz.2014.01.001","article-title":"A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease","volume":"10","author":"Jessen","year":"2014","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0085","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S1474-4422(19)30368-0","article-title":"The characterisation of subjective cognitive decline","volume":"19","author":"Jessen","year":"2020","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0090","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.arr.2016.02.003","article-title":"Brain fluorodeoxyglucose (FDG) PET in dementia","volume":"30","author":"Kato","year":"2016","journal-title":"Ageing Res Rev"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0095","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1002\/ana.410420114","article-title":"Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease","volume":"42","author":"Minoshima","year":"1997","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0100","doi-asserted-by":"crossref","first-page":"390","DOI":"10.2967\/jnumed.107.045385","article-title":"Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias","volume":"49","author":"Mosconi","year":"2008","journal-title":"J Nucl Med"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0105","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1056\/NEJMcp0910237","article-title":"Mild Cognitive Impairment","volume":"364","author":"Petersen","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0110","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1001\/jamapsychiatry.2014.2476","article-title":"Amyloid-beta, anxiety, and cognitive decline in preclinical Alzheimer disease: a multicenter, prospective cohort study","volume":"72","author":"Pietrzak","year":"2015","journal-title":"JAMA Psychiat"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0115","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/1531-8249(199903)45:3<358::AID-ANA12>3.0.CO;2-X","article-title":"Tangles and Plaques in Nondemented Aging and \u201cPreclinical\u201d Alzheimer\u2019s Disease","volume":"45","author":"Price","year":"1999","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0120","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1146\/annurev-clinpsy-032816-045136","article-title":"Subjective Cognitive Decline in Preclinical Alzheimer's Disease","volume":"13","author":"Rabin","year":"2017","journal-title":"Annu Rev Clin Psychol"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0125","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1212\/WNL.0b013e31826c1a8d","article-title":"Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment","volume":"79","author":"Scheef","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0130","doi-asserted-by":"crossref","first-page":"3323","DOI":"10.1002\/hbm.23622","article-title":"Contributions of imprecision in PET-MRI rigid registration to imprecision in amyloid PET SUVR measurements","volume":"38","author":"Schwarz","year":"2017","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0135","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1001\/jama.1997.03550160083043","article-title":"Diagnosis and treatment of Alzheimer disease and related disorders. Consensus statement of the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatrics Society","volume":"278","author":"Small","year":"1997","journal-title":"JAMA"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0140","doi-asserted-by":"crossref","first-page":"S151","DOI":"10.3233\/JAD-150113","article-title":"Amyloid-\u03b2 Imaging in Older Adults Presenting to a Memory Clinic with Subjective Cognitive Decline: A Pilot Study","volume":"48","author":"Snitz","year":"2015","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13195-020-00647-w","article-title":"Neurodegenerative changes in early- and late-onset cognitive impairment with and without brain amyloidosis","volume":"12","author":"Stage","year":"2020","journal-title":"Alzheimers Res Ther"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0150","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.neuroscience.2019.07.048","article-title":"Altered Brain Glucose Metabolism Assessed by 18F-FDG PET Imaging Is Associated with the Cognitive Impairment of CADASIL","volume":"417","author":"Su","year":"2019","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0155","doi-asserted-by":"crossref","first-page":"195","DOI":"10.3233\/JAD-180229","article-title":"Using Neuropsychological Process Scores to Identify Subtle Cognitive Decline and Predict Progression to Mild Cognitive Impairment","volume":"64","author":"Thomas","year":"2018","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0160","doi-asserted-by":"crossref","first-page":"e397","DOI":"10.1212\/WNL.0000000000008838","article-title":"Objective subtle cognitive difficulties predict future amyloid accumulation and neurodegeneration","volume":"94","author":"Thomas","year":"2020","journal-title":"Neurology"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0165","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.neurobiolaging.2019.02.020","article-title":"Amyloid PET and cognitive decline in cognitively normal individuals: the SCIENCe project","volume":"79","author":"Timmers","year":"2019","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0170","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1080\/23279095.2018.1481067","article-title":"Short-term delayed recall of auditory verbal learning test provides equivalent value to long-term delayed recall in predicting MCI clinical outcomes: A longitudinal follow-up study","volume":"27","author":"Xu","year":"2020","journal-title":"Appl Neuropsychol Adult"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0175","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s12264-013-1301-7","article-title":"Clustering and switching during a semantic verbal fluency test contribute to differential diagnosis of cognitive impairment","volume":"29","author":"Zhao","year":"2013","journal-title":"Neurosci Bull"},{"key":"10.1016\/j.neuroscience.2023.01.004_b0180","doi-asserted-by":"crossref","first-page":"520","DOI":"10.2174\/1567205012666150530202729","article-title":"Auditory Verbal Learning Test is Superior to Rey-Osterrieth Complex Figure Memory for Predicting Mild Cognitive Impairment to Alzheimer\u2019s Disease","volume":"12","author":"Zhao","year":"2015","journal-title":"Curr Alzheimer Res"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452223000088?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452223000088?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T16:17:24Z","timestamp":1759681044000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452223000088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":36,"alternative-id":["S0306452223000088"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2023.01.004","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Brain Functional Alterations and Association with Cognition in People with Preclinical Subjective Cognitive Decline and Objective Subtle Cognitive Difficulties","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2023.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 IBRO. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}