{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T19:12:07Z","timestamp":1779909127776,"version":"3.53.1"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,4]],"date-time":"2024-08-04T00:00:00Z","timestamp":1722729600000},"content-version":"am","delay-in-days":338,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ibroneuroscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.neuroscience.2023.07.017","type":"journal-article","created":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T13:37:51Z","timestamp":1690465071000},"page":"92-102","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["The Utility of Peripherally Restricted Kappa-Opioid Receptor Agonists for Inhibiting Below-Level Pain After Spinal Cord Injury in Mice"],"prefix":"10.1016","volume":"527","author":[{"given":"Danxu","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3505-5151","authenticated-orcid":false,"given":"Neil C.","family":"Ford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijuan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7306-2243","authenticated-orcid":false,"given":"Chi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3299-0726","authenticated-orcid":false,"given":"Shuguang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9490-6986","authenticated-orcid":false,"given":"Shao-Qiu","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7991-7636","authenticated-orcid":false,"given":"Srinivasa N.","family":"Raja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1321-6655","authenticated-orcid":false,"given":"Yun","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2023.07.017_b0005","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1097\/00000542-200607000-00024","article-title":"Permeability of injured and intact peripheral nerves and dorsal root ganglia","volume":"105","author":"Abram","year":"2006","journal-title":"Anesthesiology"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0010","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/sc.2016.28","article-title":"Evaluation of the effects of specific opioid receptor agonists in a rodent model of spinal cord injury","volume":"54","author":"Aceves","year":"2016","journal-title":"Spinal Cord"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0015","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1111\/jcpt.12404","article-title":"Will peripherally restricted kappa-opioid receptor agonists (pKORAs) relieve pain with less opioid adverse effects and abuse potential?","volume":"41","author":"Albert-Vartanian","year":"2016","journal-title":"J Clin Pharm Ther"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0020","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s12264-017-0139-9","article-title":"Investigation of pain mechanisms by calcium imaging approaches","volume":"34","author":"Anderson","year":"2018","journal-title":"Neurosci Bull"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0025","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1089\/neu.2006.23.635","article-title":"Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains","volume":"23","author":"Basso","year":"2006","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0030","doi-asserted-by":"crossref","DOI":"10.4155\/fdd-2019-0022","article-title":"Targeting peripheral varkappa-opioid receptors for the non-addictive treatment of pain","volume":"1","author":"Beck","year":"2019","journal-title":"Future drug discovery"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0035","doi-asserted-by":"crossref","DOI":"10.3390\/ph12020095","article-title":"Therapeutic potential of kappa opioid agonists","volume":"12","author":"Beck","year":"2019","journal-title":"Pharmaceuticals (Basel)"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2019.05.025","article-title":"Non-addictive orally-active kappa opioid agonists for the treatment of peripheral pain in rats","volume":"856","author":"Beck","year":"2019","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0045","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1124\/jpet.110.177493","article-title":"Regulation of kappa-opioid receptor signaling in peripheral sensory neurons in vitro and in vivo","volume":"338","author":"Berg","year":"2011","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0050","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/ejp.905","article-title":"Neuropathic pain prevalence following spinal cord injury: a systematic review and meta-analysis","volume":"21","author":"Burke","year":"2017","journal-title":"Eur J Pain (London, England)"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0055","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ejphar.2007.06.034","article-title":"Subcutaneous, intrathecal and periaqueductal grey administration of asimadoline and ICI-204448 reduces tactile allodynia in the rat","volume":"573","author":"Caram-Salas","year":"2007","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0060","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.1038\/npp.2013.171","article-title":"Kappa opioid receptors on dopaminergic neurons are necessary for kappa-mediated place aversion","volume":"38","author":"Chefer","year":"2013","journal-title":"Neuropsychopharmacol: Official Publ Am College Neuropsychopharmacol"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0065","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1744-8069-8-10","article-title":"Stimulation of peripheral kappa opioid receptors inhibits inflammatory hyperalgesia via activation of the PI3Kgamma\/AKT\/nNOS\/NO signaling pathway","volume":"8","author":"Cunha","year":"2012","journal-title":"Mol Pain"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0070","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1016\/S0304-3959(99)00135-9","article-title":"Unexplained peculiarities of the dorsal root ganglion","volume":"6","author":"Devor","year":"1999","journal-title":"Pain Suppl"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.neulet.2019.134358","article-title":"Comparisons of motor and sensory abnormalities after lumbar and thoracic contusion spinal cord injury in male rats","volume":"708","author":"Duan","year":"2019","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0080","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.jpain.2018.01.002","article-title":"A kappa opioid receptor agonist blocks bone cancer pain without altering bone loss, tumor size, or cancer cell proliferation in a mouse model of cancer-induced bone pain","volume":"19","author":"Edwards","year":"2018","journal-title":"J Pain"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0085","doi-asserted-by":"crossref","first-page":"12917","DOI":"10.1523\/JNEUROSCI.2444-15.2015","article-title":"Kappa opioid receptor-induced aversion requires p38 MAPK activation in VTA dopamine neurons","volume":"35","author":"Ehrich","year":"2015","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0090","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.ekir.2020.01.006","article-title":"Randomized controlled trial of difelikefalin for chronic pruritus in hemodialysis patients","volume":"5","author":"Fishbane","year":"2020","journal-title":"Kidney Int Rep"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0095","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1177\/10600280221115889","article-title":"Difelikefalin: a new kappa-opioid receptor agonist for the treatment of hemodialysis-dependent chronic kidney disease-associated pruritus","volume":"57","author":"Fugal","year":"2023","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2020.108943","article-title":"Nicotine-induced autophagy via AMPK\/mTOR pathway exerts protective effect in colitis mouse model","author":"Gao","year":"2020","journal-title":"Chemico-Biol Intract"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0105","article-title":"Calcium imaging in population of dorsal root ganglion neurons unravels novel mechanisms of visceral pain sensitization and referred somatic hypersensitivity","author":"Gao","year":"2020","journal-title":"Pain"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0110","doi-asserted-by":"crossref","first-page":"5469","DOI":"10.1073\/pnas.84.15.5469","article-title":"Dynorphin A selectively reduces a large transient (N-type) calcium current of mouse dorsal root ganglion neurons in cell culture","volume":"84","author":"Gross","year":"1987","journal-title":"ProcNatlAcadSciUSA"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0115","doi-asserted-by":"crossref","first-page":"11429","DOI":"10.1073\/pnas.90.23.11429","article-title":"kappa-Opioid receptors also increase potassium conductance","volume":"90","author":"Grudt","year":"1993","journal-title":"PNAS"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0120","doi-asserted-by":"crossref","first-page":"15933","DOI":"10.1073\/pnas.1011221107","article-title":"Mas-related G-protein-coupled receptors inhibit pathological pain in mice","volume":"107","author":"Guan","year":"2010","journal-title":"PNAS"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0125","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0304-3959(88)90026-7","article-title":"A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia","volume":"32","author":"Hargreaves","year":"1988","journal-title":"Pain"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0130","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1089\/neu.2016.4507","article-title":"Neurobiological Effects of Morphine after Spinal Cord Injury","volume":"34","author":"Hook","year":"2017","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0135","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.brainresrev.2008.12.010","article-title":"Mechanisms of chronic central neuropathic pain after spinal cord injury","volume":"60","author":"Hulsebosch","year":"2009","journal-title":"Brain Res Rev"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0140","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1089\/neu.2000.17.1205","article-title":"Rodent model of chronic central pain after spinal cord contusion injury and effects of gabapentin","volume":"17","author":"Hulsebosch","year":"2000","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0145","article-title":"Calcium imaging for analgesic drug discovery","volume":"11","author":"Iseppon","year":"2022","journal-title":"Neurobiol Pain"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2022.174961","article-title":"ZYKR1, a novel, potent, and peripherally selective kappa opioid receptor agonist reduces visceral pain and pruritus in animal models","volume":"924","author":"Jain","year":"2022","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0155","doi-asserted-by":"crossref","first-page":"8156","DOI":"10.1523\/JNEUROSCI.15-12-08156.1995","article-title":"Expression of mu-, delta-, and kappa-opioid receptor-like immunoreactivities in rat dorsal root ganglia after carrageenan-induced inflammation","volume":"15","author":"Ji","year":"1995","journal-title":"J Neurosci"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0160","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/0014-2999(95)00122-2","article-title":"Antinociceptive effect of a kappa-opioid receptor agonist that minimally crosses the blood-brain barrier (ICI 204448) in a rat model of mononeuropathy","volume":"277","author":"Keita","year":"1995","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0165","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.neuron.2016.07.044","article-title":"Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain","volume":"91","author":"Kim","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0170","doi-asserted-by":"crossref","DOI":"10.1038\/s41393-020-00599-w","article-title":"Post-traumatic stress disorder symptoms and pain intensity in persons with spinal cord injury","author":"Kuiper","year":"2021","journal-title":"Spinal Cord"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0175","first-page":"E1996","article-title":"Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain","volume":"114","author":"Li","year":"2017","journal-title":"PNAS"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0180","first-page":"1","article-title":"An evaluation of difelikefalin as a treatment option for moderate-to-severe pruritus in end stage renal disease","author":"Lipman","year":"2020","journal-title":"Expert Opin Pharmacotherap"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0185","doi-asserted-by":"crossref","first-page":"2710","DOI":"10.1097\/j.pain.0000000000001671","article-title":"Dermorphin [D-Arg2, Lys4] (1\u20134) amide inhibits below-level heat hypersensitivity in mice after contusive thoracic spinal cord injury","volume":"160","author":"Liu","year":"2019","journal-title":"Pain"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0190","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/art.40342","article-title":"Visualization of peripheral neuron sensitization in a surgical mouse model of osteoarthritis by in vivo calcium imaging","volume":"70","author":"Miller","year":"2018","journal-title":"Arthritis Rheumatol"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0195","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1097\/j.pain.0000000000001846","article-title":"Distribution of functional opioid receptors in human dorsal root ganglion neurons","volume":"161","author":"Moy","year":"2020","journal-title":"Pain"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0200","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/j.neuron.2018.09.006","article-title":"Peripheral kappa opioid receptor signaling takes on a central role","volume":"99","author":"Naser","year":"2018","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0205","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1097\/j.pain.0000000000001458","article-title":"Kappa opioid signaling in the central nucleus of the amygdala promotes disinhibition and aversiveness of chronic neuropathic pain","volume":"160","author":"Navratilova","year":"2019","journal-title":"Pain"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0210","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/j.pain.0000000000000783","article-title":"Neuropathic pain after spinal cord injury: the impact of sensorimotor activity","volume":"158","author":"Nees","year":"2017","journal-title":"Pain"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0215","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1124\/jpet.111.186783","article-title":"Effects of peripherally restricted kappa opioid receptor agonists on pain-related stimulation and depression of behavior in rats","volume":"340","author":"Negus","year":"2012","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0220","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1124\/jpet.120.000134","article-title":"Strategies for developing kappa opioid receptor agonists for the treatment of pain with fewer side effects","volume":"375","author":"Paton","year":"2020","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0225","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1159\/000083704","article-title":"Peripheral kappa-opioid agonist, ICI 204448, evokes hypothermia in cold-exposed rats","volume":"74","author":"Rawls","year":"2005","journal-title":"Pharmacology"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0230","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1007\/s13311-018-0633-4","article-title":"Neuropathic pain after spinal cord injury: challenges and research perspectives","volume":"15","author":"Shiao","year":"2018","journal-title":"Neurotherapeutics"},{"issue":"1274\u20131288","key":"10.1016\/j.neuroscience.2023.07.017_b0235","first-page":"e1276","article-title":"Kappa opioid receptor distribution and function in primary afferents","volume":"99","author":"Snyder","year":"2018","journal-title":"Neuron"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0240","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1097\/ALN.0000000000002191","article-title":"Peripherally acting mu-opioid receptor agonists attenuate ongoing pain-associated behavior and spontaneous neuronal activity after nerve injury in rats","volume":"128","author":"Tiwari","year":"2018","journal-title":"Anesthesiology"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0245","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1097\/ALN.0000000000000993","article-title":"Activation of peripheral mu-opioid receptors by dermorphin [D-Arg2, Lys4] (1\u20134) amide leads to modality-preferred inhibition of neuropathic pain","volume":"124","author":"Tiwari","year":"2016","journal-title":"Anesthesiology"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0250","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ejphar.2008.01.011","article-title":"Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors","volume":"583","author":"Vanderah","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0255","article-title":"Antinociceptive and antipruritic effects of HSK21542, a peripherally-restricted kappa opioid receptor agonist, in animal models of pain and itch","volume":"12","author":"Wang","year":"2021","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0260","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1007\/s40265-017-0747-8","article-title":"Neuropathic pain and spinal cord injury: phenotypes and pharmacological management","volume":"77","author":"Widerstrom-Noga","year":"2017","journal-title":"Drugs"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0265","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1089\/neu.2010.1311","article-title":"Below level central pain induced by discrete dorsal spinal cord injury","volume":"27","author":"Wieseler","year":"2010","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.neuroscience.2023.07.017_b0270","doi-asserted-by":"crossref","first-page":"10765","DOI":"10.1523\/JNEUROSCI.5316-13.2014","article-title":"Persistent pain after spinal cord injury is maintained by primary afferent activity","volume":"34","author":"Yang","year":"2014","journal-title":"J Neurosci"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452223003196?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452223003196?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T16:19:32Z","timestamp":1759681172000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452223003196"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":54,"alternative-id":["S0306452223003196"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2023.07.017","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Utility of Peripherally Restricted Kappa-Opioid Receptor Agonists for Inhibiting Below-Level Pain After Spinal Cord Injury in Mice","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2023.07.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 IBRO. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}