{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T18:37:54Z","timestamp":1784399874203,"version":"3.55.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ibroneuroscience.org","clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.neuroscience.2025.03.045","type":"journal-article","created":{"date-parts":[[2025,3,23]],"date-time":"2025-03-23T12:37:12Z","timestamp":1742733432000},"page":"237-243","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Effect of chronic sustained hypoxia on NPR-A, NPR-B, MAP-2 and GFAP expressions in cerebral cortex and hippocampus"],"prefix":"10.1016","volume":"573","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2067-6174","authenticated-orcid":false,"given":"Derya","family":"Karabulut","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6035-9398","authenticated-orcid":false,"given":"Kemal Erdem","family":"Ba\u015faran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nurhan","family":"Kulo\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Necla","family":"De\u011fer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birkan","family":"Yakan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.neuroscience.2025.03.045_b0005","doi-asserted-by":"crossref","first-page":"C951","DOI":"10.1152\/ajpcell.00512.2010","article-title":"4. Hypoxia and ion channel function","volume":"300","author":"Shimoda","year":"2011","journal-title":"Am J Physiol Cell Physiol."},{"issue":"Suppl 1","key":"10.1016\/j.neuroscience.2025.03.045_b0010","doi-asserted-by":"crossref","first-page":"S89","DOI":"10.33549\/physiolres.932374","article-title":"Hypoxia-induced lipid peroxidation in the brain during postnatal ontogenesis","volume":"61","author":"Rauchov\u00e1","year":"2012","journal-title":"Physiol Res."},{"key":"10.1016\/j.neuroscience.2025.03.045_b0015","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/978-1-4615-4711-2_14","article-title":"The hypoxic brain. Insights from ischemia research","volume":"474","author":"Hossmann","year":"1999","journal-title":"Adv Exp Med Biol."},{"issue":"2","key":"10.1016\/j.neuroscience.2025.03.045_b0020","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1093\/bja\/47.2.121","article-title":"Hypoxic brain damage","volume":"47","author":"Adams","year":"1975","journal-title":"Br J Anaesth."},{"key":"10.1016\/j.neuroscience.2025.03.045_b0025","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/978-1-4899-7678-9_14","article-title":"Astrocytes and Brain Hypoxia","volume":"903","author":"Marina","year":"2016","journal-title":"Adv Exp Med Biol."},{"key":"10.1016\/j.neuroscience.2025.03.045_b0030","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/978-1-4899-7678-9_9","article-title":"Influence of Hypoxia on Cerebral Blood Flow Regulation in Humans","volume":"903","author":"Steinback","year":"2016","journal-title":"Adv Exp Med Biol."},{"issue":"2","key":"10.1016\/j.neuroscience.2025.03.045_b0035","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1113\/expphysiol.2008.045575","article-title":"Regulation of cerebral blood flow in mammals during chronic hypoxia: a matter of balance","volume":"95","author":"Ainslie","year":"2010","journal-title":"Exp Physiol."},{"issue":"6","key":"10.1016\/j.neuroscience.2025.03.045_b0040","first-page":"1548","article-title":"Molecular biology and pharmacology of natriuretic peptide system","volume":"51","author":"Itoh","year":"1993","journal-title":"Nihon Rinsho."},{"issue":"3","key":"10.1016\/j.neuroscience.2025.03.045_b0045","first-page":"134","article-title":"Natriuretic peptide family","volume":"68","author":"Nakao","year":"1992","journal-title":"Nihon Naibunpi Gakkai Zasshi."},{"key":"10.1016\/j.neuroscience.2025.03.045_b0050","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/978-3-540-68964-5_15","article-title":"Natriuretic peptides: their structures, receptors, physiologic functions and therapeutic applications","volume":"191","author":"Potter","year":"2009","journal-title":"Handb Exp Pharmacol."},{"issue":"1","key":"10.1016\/j.neuroscience.2025.03.045_b0055","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.neuroscience.2008.05.020","article-title":"Distribution of natriuretic peptide receptor-C immunoreactivity in the rat brainstem and its relationship to cholinergic and catecholaminergic neurons","volume":"155","author":"Abdelalim","year":"2008","journal-title":"Neuroscience."},{"issue":"11","key":"10.1016\/j.neuroscience.2025.03.045_b0060","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1111\/j.1742-4658.2011.08083.x","article-title":"Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase","volume":"278","author":"Misono","year":"2011","journal-title":"Febs J."},{"issue":"2","key":"10.1016\/j.neuroscience.2025.03.045_b0065","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1152\/physrev.1997.77.2.465","article-title":"Atrial natriuretic peptide in brain and pituitary gland","volume":"77","author":"Gutkowska","year":"1997","journal-title":"Physiol Rev."},{"issue":"6","key":"10.1016\/j.neuroscience.2025.03.045_b0070","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.peptides.2004.08.030","article-title":"Atrial natriuretic peptide in hypoxia","volume":"26","author":"Chen","year":"2005","journal-title":"Peptides."},{"issue":"7","key":"10.1016\/j.neuroscience.2025.03.045_b0075","first-page":"3454","article-title":"Differential regional expression of three natriuretic peptide receptor genes within primate tissues","volume":"11","author":"Wilcox","year":"1991","journal-title":"Mol Cell Biol."},{"issue":"2","key":"10.1016\/j.neuroscience.2025.03.045_b0080","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1152\/advan.00177.2016","article-title":"The renal and cardiovascular effects of natriuretic peptides","volume":"41","author":"Wong","year":"2017","journal-title":"Adv Physiol Educ."},{"issue":"12","key":"10.1016\/j.neuroscience.2025.03.045_b0085","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1007\/s00210-020-01992-1","article-title":"Effects of vitamin B12 on methotrexate hepatotoxicity: evaluation of receptor-interacting protein (RIP) kinase","volume":"393","author":"Karabulut","year":"2020","journal-title":"Naunyn-Schmiedeberg's Archives of Pharmacology."},{"key":"10.1016\/j.neuroscience.2025.03.045_b0090","article-title":"Thymoquinone is a protective agent that reduces the negative effects of doxorubicin in rat testis","volume":"960327120924108","author":"\u00d6zt\u00fcrk","year":"2020","journal-title":"Hum Exp Toxicol."},{"issue":"10","key":"10.1016\/j.neuroscience.2025.03.045_b0095","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.4187\/respcare.03357","article-title":"Tissue hypoxia: implications for the respiratory clinician","volume":"59","author":"MacIntyre","year":"2014","journal-title":"Respir Care."},{"issue":"1","key":"10.1016\/j.neuroscience.2025.03.045_b0100","first-page":"95","article-title":"Brain hypoxia and the role of active forms of oxygen and of energy deficit in the neuron degeneration","volume":"43","author":"Ivanov","year":"2012","journal-title":"Usp Fiziol Nauk."},{"issue":"3","key":"10.1016\/j.neuroscience.2025.03.045_b0105","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1177\/1925362118797728","article-title":"Histology of Brain Trauma and Hypoxia-Ischemia","volume":"8","author":"Rahaman","year":"2018","journal-title":"Acad Forensic Pathol."},{"key":"10.1016\/j.neuroscience.2025.03.045_b0110","doi-asserted-by":"crossref","unstructured":"Fletcher EC. Invited review: Physiological consequences of intermittent hypoxia: systemic blood pressure. J Appl Physiol (1985). 2001;90(4):1600-5.","DOI":"10.1152\/jappl.2001.90.4.1600"},{"issue":"8","key":"10.1016\/j.neuroscience.2025.03.045_b0115","first-page":"601","article-title":"Effects of chronic intermittent hypoxia on blood pressure and vascular remodeling","volume":"54","author":"Tang","year":"2019","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi."},{"issue":"4","key":"10.1016\/j.neuroscience.2025.03.045_b0120","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1615\/CritRevBiomedEng.v40.i4.30","article-title":"Molecular mechanisms of chronic intermittent hypoxia and hypertension","volume":"40","author":"Sunderram","year":"2012","journal-title":"Crit Rev Biomed Eng."},{"issue":"3","key":"10.1016\/j.neuroscience.2025.03.045_b0125","first-page":"217","article-title":"The natriuretic peptide system in the brain: implications in the central control of cardiovascular and neuroendocrine functions","volume":"13","author":"Imura","year":"1992","journal-title":"Front Neuroendocrinol."},{"key":"10.1016\/j.neuroscience.2025.03.045_b0130","doi-asserted-by":"crossref","unstructured":"Steinhelper ME, Cochrane KL, Field LJ. Hypotension in transgenic mice expressing atrial natriuretic factor fusion genes. Hypertension (Dallas, Tex : 1979). 1990;16(3):301-7.","DOI":"10.1161\/01.HYP.16.3.301"},{"issue":"5","key":"10.1016\/j.neuroscience.2025.03.045_b0135","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1172\/JCI117182","article-title":"Molecular cloning of the complementary DNA and gene that encode mouse brain natriuretic peptide and generation of transgenic mice that overexpress the brain natriuretic peptide gene","volume":"93","author":"Ogawa","year":"1994","journal-title":"The Journal of Clinical Investigation."},{"issue":"3","key":"10.1016\/j.neuroscience.2025.03.045_b0140","doi-asserted-by":"crossref","first-page":"239","DOI":"10.4103\/bbrj.bbrj_44_20","article-title":"Brain natriuretic peptide in patients with acute ischemic stroke: role of statins","volume":"4","author":"Al-Kuraishy","year":"2020","journal-title":"Biomedical and Biotechnology Research Journal (BBRJ)."},{"issue":"5","key":"10.1016\/j.neuroscience.2025.03.045_b0145","doi-asserted-by":"crossref","first-page":"321","DOI":"10.2174\/1389203723666220628114928","article-title":"Targeting and Modulation of the Natriuretic Peptide System in Covid-19: A Single or Double-Edged Effect?","volume":"23","author":"Al-Kuraishy","year":"2022","journal-title":"Curr Protein Pept Sci."},{"key":"10.1016\/j.neuroscience.2025.03.045_b0150","doi-asserted-by":"crossref","unstructured":"K\u00fchn J, Meissner C, Oehmichen M. Microtubule-associated protein 2 (MAP2)--a promising approach to diagnosis of forensic types of hypoxia-ischemia. Acta Neuropathol. 2005;110(6):579-86.","DOI":"10.1007\/s00401-005-1090-9"},{"issue":"4","key":"10.1016\/j.neuroscience.2025.03.045_b0155","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1002\/path.1645","article-title":"Astrocyte intermediate filaments in CNS pathologies and regeneration","volume":"204","author":"Pekny","year":"2004","journal-title":"J Pathol."},{"issue":"4","key":"10.1016\/j.neuroscience.2025.03.045_b0160","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/S1344-6223(03)00077-4","article-title":"Methodical approach to brain hypoxia\/ischemia as a fundamental problem in forensic neuropathology","volume":"5","author":"Oehmichen","year":"2003","journal-title":"Leg Med (tokyo)."},{"key":"10.1016\/j.neuroscience.2025.03.045_b0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.jchemneu.2021.101957","article-title":"The role of monoamine oxidase enzymes in the pathophysiology of neurological disorders","volume":"114","author":"Jones","year":"2021","journal-title":"J Chem Neuroanat."},{"issue":"11","key":"10.1016\/j.neuroscience.2025.03.045_b0170","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1001\/archpsyc.63.11.1209","article-title":"Elevated monoamine oxidase a levels in the brain: an explanation for the monoamine imbalance of major depression","volume":"63","author":"Meyer","year":"2006","journal-title":"Arch Gen Psychiatry."},{"key":"10.1016\/j.neuroscience.2025.03.045_b0175","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.pnpbp.2016.02.005","article-title":"Molecular aspects of monoamine oxidase B","volume":"69","author":"Ramsay","year":"2016","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry."}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452225002477?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452225002477?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T04:08:48Z","timestamp":1746158928000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452225002477"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":35,"alternative-id":["S0306452225002477"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2025.03.045","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of chronic sustained hypoxia on NPR-A, NPR-B, MAP-2 and GFAP expressions in cerebral cortex and hippocampus","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2025.03.045","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 International Brain Research Organization (IBRO). Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}