{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T01:43:19Z","timestamp":1794534199902,"version":"4.9.1"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004160","name":"Mazandaran University of Medical Sciences","doi-asserted-by":"publisher","award":["10287"],"award-info":[{"award-number":["10287"]}],"id":[{"id":"10.13039\/501100004160","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ibroneuroscience.org","clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.neuroscience.2025.04.042","type":"journal-article","created":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T14:20:00Z","timestamp":1745763600000},"page":"96-104","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Perinatal thyroid hormone deficiency leads to oxidative stress-induced neuronal damage and activation of astrocytes in rat hippocampus: Neuroprotective effect of exercise"],"prefix":"10.1016","volume":"576","author":[{"given":"Zohreh","family":"Zare","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Zarbakhsh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moslem","family":"Mohammadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2025.04.042_b0005","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.ijdevneu.2007.09.011","article-title":"Thyroid hormones states and brain development interactions","volume":"26","author":"Ahmed","year":"2008","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0010","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.brainresbull.2004.02.002","article-title":"Kainic acid does not affect CA3 hippocampal region pyramidal cells in hypothyroid rats","volume":"63","author":"Alva-S\u00e1nchez","year":"2004","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0015","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/bs.vh.2022.09.002","article-title":"The antioxidant glutathione","volume":"121","author":"Averill-Bates","year":"2023","journal-title":"Vitam. Horm."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0020","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1111\/j.1471-4159.2006.03913.x","article-title":"The glutamate\/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer","volume":"98","author":"Bak","year":"2006","journal-title":"J. Neurochem."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0025","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1152\/japplphysiol.00425.2011","article-title":"Pall\u00e0s M (2011) Long-term treadmill exercise induces neuroprotective molecular changes in rat brain","volume":"111","author":"Bayod","year":"1985","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0030","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0035","doi-asserted-by":"crossref","first-page":"e202","DOI":"10.1111\/sms.12065","article-title":"Does exercise reduce brain oxidative stress? A systematic review","volume":"23","author":"Camiletti-Moir\u00f3n","year":"2013","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0040","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1016\/j.metabol.2007.04.003","article-title":"Changes in acetylcholinesterase, Na+,K+-ATPase, and Mg2+-ATPase activities in the frontal cortex and the hippocampus of hyper- and hypothyroid adult rats","volume":"56","author":"Carageorgiou","year":"2007","journal-title":"Metabolism"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0045","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.mce.2013.05.001","article-title":"Congenital hypothyroidism alters the oxidative status, enzyme activities and morphological parameters in the hippocampus of developing rats","volume":"375","author":"Cattani","year":"2013","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10715762.2019.1702656","article-title":"Hormones and oxidative stress: an overview","volume":"54","author":"Chainy","year":"2020","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0055","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.redox.2017.02.014","article-title":"Oxidative stress and apoptosis after acute respiratory hypoxia and reoxygenation in rat brain","volume":"12","author":"Coimbra-Costa","year":"2017","journal-title":"Redox Biol."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0060","doi-asserted-by":"crossref","first-page":"3864","DOI":"10.1210\/jcem.86.8.7749","article-title":"Cerebral blood flow and glucose metabolism in hypothyroidism: a positron emission tomography study","volume":"86","author":"Constant","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0065","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/8856621","article-title":"Effects of Physical Exercise on Neuroplasticity and Brain Function: A Systematic Review in Human and Animal Studies","volume":"2020","author":"de Sousa Fernandes","year":"2020","journal-title":"Neural Plast."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0070","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0301-0082(99)00060-X","article-title":"Metabolism and functions of glutathione in brain","volume":"62","author":"Dringen","year":"2000","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0075","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.neuroscience.2011.06.066","article-title":"Effect of different exercise protocols on histone acetyltransferases and histone deacetylases activities in rat hippocampus","volume":"192","author":"Elsner","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0080","doi-asserted-by":"crossref","first-page":"e30","DOI":"10.1542\/neo.21-1-e30","article-title":"Thyroid Function During the Fetal and Neonatal Periods","volume":"21","author":"Eng","year":"2020","journal-title":"NeoReviews"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0085","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.brainres.2011.10.004","article-title":"Short-term, moderate exercise is capable of inducing structural, BDNF-independent hippocampal plasticity","volume":"1425","author":"Ferreira","year":"2011","journal-title":"Brain Res."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0090","first-page":"854","article-title":"Do prenatal and postnatal hypothyroidism affect the craniofacial structure?: An experimental study","volume":"86","author":"Gecgelen Cesur","year":"2016","journal-title":"Angle Orthod."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0095","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/j.etap.2012.08.011","article-title":"Effects of paraoxon on serum biochemical parameters and oxidative stress induction in various tissues of Wistar and Norway rats","volume":"34","author":"Jafari","year":"2012","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0100","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s11011-012-9291-0","article-title":"Thyroid hormone's role in regulating brain glucose metabolism and potentially modulating hippocampal cognitive processes","volume":"27","author":"Jahagirdar","year":"2012","journal-title":"Metab. Brain Dis."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0105","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1007\/s10072-015-2199-9","article-title":"Effect of persistent and transient hypothyroidism on histoarchitecture and antioxidant defence system in rat brain","volume":"36","author":"Jena","year":"2015","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0110","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1515\/jpem-2018-0197","article-title":"Congenital hypothyroidism","volume":"31","author":"Kiess","year":"2018","journal-title":"J. Pediatr. Endocrinol. Metab."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0115","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1080\/14734220410029650","article-title":"Impact of thyroid hormone deficiency on the developing CNS: cerebellar glial and neuronal protein expression in rat neonates exposed to antithyroid drug propylthiouracil","volume":"3","author":"Li","year":"2004","journal-title":"Cerebellum"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0120","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/B978-0-444-64189-2.00023-8","article-title":"Endocrine disorders and the cerebellum: from neurodevelopmental injury to late-onset ataxia","volume":"155","author":"Manto","year":"2018","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0125","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.freeradbiomed.2005.05.003","article-title":"Antioxidant strategies in the treatment of stroke","volume":"39","author":"Margaill","year":"2005","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0130","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.jnutbio.2005.05.013","article-title":"Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes","volume":"16","author":"Masella","year":"2005","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0135","doi-asserted-by":"crossref","first-page":"979","DOI":"10.3349\/ymj.2003.44.6.979","article-title":"Lipid peroxidation, erythrocyte superoxide-dismutase activity and trace metals in young male footballers","volume":"44","author":"Metin","year":"2003","journal-title":"Yonsei Med. J."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0140","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.pneurobio.2011.01.005","article-title":"GFAP in health and disease","volume":"93","author":"Middeldorp","year":"2011","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0145","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.920","article-title":"Maternal hormonal milieu influence on fetal brain development","volume":"8","author":"Miranda","year":"2018","journal-title":"Brain Behav."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0150","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2021.617588","article-title":"Mitochondrial dysfunction and oxidative stress in Alzheimer's disease","volume":"13","author":"Misrani","year":"2021","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0155","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.neuro.2016.10.009","article-title":"Alterations in mRNA and protein expression of glutamate transporters in rat hippocampus after paraoxon exposure","volume":"57","author":"Mohammadi","year":"2016","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0160","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.neuroscience.2015.09.070","article-title":"Influence of maternal thyroid hormones during gestation on fetal brain development","volume":"342","author":"Moog","year":"2017","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2021.113594","article-title":"Early postnatal hypothyroidism reduces juvenile play behavior, but prenatal hypothyroidism compensates for these effects","volume":"241","author":"Northcutt","year":"2021","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0170","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1159\/000106821","article-title":"Ontogenesis of thyroid function and interactions with maternal function","volume":"10","author":"Obregon","year":"2007","journal-title":"Endocr. Dev."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0175","first-page":"10","article-title":"Circulating malondialdehyde concentrations in obstructive sleep apnea (OSA): A systematic review and meta-analysis with meta-regression","author":"Pau","year":"2021","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0180","first-page":"129","article-title":"Neutrophil activation, antioxidant supplements and exercise-induced oxidative stress","volume":"10","author":"Peake","year":"2004","journal-title":"Exerc. Immunol. Rev."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0185","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1159\/000492129","article-title":"Effect of thyroid hormones on neurons and neurodevelopment","volume":"90","author":"Prezioso","year":"2018","journal-title":"Horm. Res. Paediatr."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0190","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0168-0102(01)00237-1","article-title":"Hypothyroidism in the developing rat brain is associated with marked oxidative stress and aberrant intraneuronal accumulation of neurofilaments","volume":"40","author":"Rahaman","year":"2001","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0195","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1097\/FBP.0000000000000572","article-title":"Effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats","volume":"31","author":"Rashidy-Pour","year":"2020","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0200","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1515\/cclm.2002.198","article-title":"Antioxidant status in thyroid dysfunction","volume":"40","author":"Resch","year":"2002","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0205","article-title":"The effect of aerobic exercise in neuroplasticity, learning, and cognition: A systematic review","volume":"16","author":"Revelo Herrera","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0210","doi-asserted-by":"crossref","first-page":"2701","DOI":"10.1073\/pnas.1817885116","article-title":"The glutathione cycle shapes synaptic glutamate activity","volume":"116","author":"Sedlak","year":"2019","journal-title":"PNAS"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0215","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.ijdevneu.2013.01.003","article-title":"Treadmill exercise ameliorates symptoms of methimazole-induced hypothyroidism through enhancing neurogenesis and suppressing apoptosis in the hippocampus of rat pups","volume":"31","author":"Shin","year":"2013","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0220","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1007\/s00204-012-0846-y","article-title":"Similar distribution changes of GABAergic interneuron subpopulations in contrast to the different impact on neurogenesis between developmental and adult-stage hypothyroidism in the hippocampal dentate gyrus in rats","volume":"86","author":"Shiraki","year":"2012","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0225","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1097\/00005768-200002000-00011","article-title":"Cytokine hypothesis of overtraining: a physiological adaptation to excessive stress?","volume":"32","author":"Smith","year":"2000","journal-title":"Med. Sci. Sports Exerc."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0230","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1177\/1073858405278321","article-title":"Reactive astrocytes in neural repair and protection","volume":"11","author":"Sofroniew","year":"2005","journal-title":"Neuroscientist"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0235","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3389\/fendo.2019.00209","article-title":"Transport, metabolism, and function of thyroid hormones in the developing mammalian brain","volume":"10","author":"Stepien","year":"2019","journal-title":"Front Endocrinol (lausanne)"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0240","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.seizure.2015.07.021","article-title":"Thyroid hormones: Possible roles in epilepsy pathology","volume":"31","author":"Tamijani","year":"2015","journal-title":"Seizure"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0245","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/2089404","article-title":"Hypothyroidism causes endoplasmic reticulum stress in adult rat hippocampus: A mechanism associated with hippocampal damage","volume":"2018","author":"Torres-Manzo","year":"2018","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0250","first-page":"H2181","article-title":"Oxidative stress and heart failure","volume":"301","author":"Tsutsui","year":"2011","journal-title":"Am. J. Phys. Heart Circ. Phys."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0255","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1089\/thy.2020.0333","article-title":"Congenital hypothyroidism: A 2020-2021 consensus guidelines update-an ENDO-European reference network initiative endorsed by the European Society for Pediatric Endocrinology and the European Society for Endocrinology","volume":"31","author":"van Trotsenburg","year":"2021","journal-title":"Thyroid"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0260","first-page":"12","article-title":"Selective neuronal vulnerability to oxidative stress in the brain","volume":"2","author":"Wang","year":"2010","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0265","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/j.1365-2826.2008.01733.x","article-title":"Neurodevelopmental and neurophysiological actions of thyroid hormone","volume":"20","author":"Williams","year":"2008","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0270","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.tins.2015.04.003","article-title":"Glial fibrillary acidic protein: from intermediate filament assembly and gliosis to neurobiomarker","volume":"38","author":"Yang","year":"2015","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0275","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.neuro.2008.09.004","article-title":"Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain","volume":"29","author":"Zamoner","year":"2008","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.yhbeh.2024.105548","article-title":"Thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring","volume":"162","author":"Zare","year":"2024","journal-title":"Horm. Behav."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0285","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/s12640-019-00106-x","article-title":"Effects of paraoxon exposure on expression of apoptosis-related genes, neuronal survival, and astrocyte activation in rat prefrontal cortex","volume":"37","author":"Zare","year":"2020","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2020.104580","article-title":"Paraoxon-induced damage in rat hippocampus is associated with alterations in the expression of apoptosis-related proteins","volume":"166","author":"Zare","year":"2020","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.neuroscience.2025.04.042_b0295","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.neuroscience.2022.06.012","article-title":"Neuroprotective effects of treadmill exercise in hippocampus of ovariectomized and diabetic rats","volume":"496","author":"Zare","year":"2022","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2025.04.042_b0300","first-page":"289","article-title":"Brain oxygenation and energy metabolism: part I-biological function and pathophysiology","volume":"51","author":"Zauner","year":"2002","journal-title":"Neurosurgery"}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452225003355?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452225003355?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T12:25:26Z","timestamp":1747398326000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452225003355"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":60,"alternative-id":["S0306452225003355"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2025.04.042","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Perinatal thyroid hormone deficiency leads to oxidative stress-induced neuronal damage and activation of astrocytes in rat hippocampus: Neuroprotective effect of exercise","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2025.04.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 International Brain Research Organization (IBRO). Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}