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Neurobiol."},{"issue":"9","key":"10.1016\/j.neuroscience.2025.04.044_b0455","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1038\/sj.emboj.7601083","article-title":"TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion","volume":"25","author":"Togashi","year":"2006","journal-title":"EMBO. J."},{"issue":"1","key":"10.1016\/j.neuroscience.2025.04.044_b0460","doi-asserted-by":"crossref","first-page":"5274","DOI":"10.1038\/s41467-021-25456-z","article-title":"BMP8 and activated brown adipose tissue in human newborns","volume":"12","author":"Urisarri","year":"2021","journal-title":"Nat. Commun."},{"issue":"6","key":"10.1016\/j.neuroscience.2025.04.044_b0465","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.jhevol.2005.08.001","article-title":"Human encephalization and developmental timing","volume":"49","author":"Vinicius","year":"2005","journal-title":"J. Hum. Evol."},{"issue":"9","key":"10.1016\/j.neuroscience.2025.04.044_b0470","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/nrn3784","article-title":"Peripheral thermosensation in mammals","volume":"15","author":"Vriens","year":"2014","journal-title":"Nat. Rev. Neurosci."},{"issue":"3","key":"10.1016\/j.neuroscience.2025.04.044_b0475","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1469-445X.2000.01909.x","article-title":"Thermoregulation in winter swimmers and physiological significance of human catecholamine thermogenesis","volume":"85","author":"Vyb\u00edral","year":"2000","journal-title":"Exp. Physiol."},{"issue":"2","key":"10.1016\/j.neuroscience.2025.04.044_b0480","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1080\/23328940.2015.1040604","article-title":"TRP ion channels in thermosensation, thermoregulation and metabolism","volume":"2","author":"Wang","year":"2015","journal-title":"Temperature (austin, Tex.)"},{"issue":"4","key":"10.1016\/j.neuroscience.2025.04.044_b0485","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.cell.2012.02.066","article-title":"BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions","volume":"149","author":"Whittle","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2025.04.044_b0490","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1152\/jappl.1965.20.1.31","article-title":"Role of skin and of core temperatures in man's temperature regulation","volume":"20","author":"Wyndham","year":"1965","journal-title":"J. Appl. Physiol."},{"issue":"11","key":"10.1016\/j.neuroscience.2025.04.044_b0495","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1167\/iovs.64.11.1","article-title":"Early visual deprivation impairs functional development of the visual ventral stream","volume":"64","author":"Xiang","year":"2023","journal-title":"Invest. Ophthalmol. vis. Sci."},{"issue":"28","key":"10.1016\/j.neuroscience.2025.04.044_b0500","doi-asserted-by":"crossref","first-page":"5221","DOI":"10.1523\/JNEUROSCI.0643-23.2023","article-title":"Two ascending thermosensory pathways from the lateral parabrachial nucleus that mediate behavioral and autonomous thermoregulation","volume":"43","author":"Yahiro","year":"2023","journal-title":"J. Neurosci."},{"issue":"15","key":"10.1016\/j.neuroscience.2025.04.044_b0505","doi-asserted-by":"crossref","first-page":"8633","DOI":"10.1073\/pnas.1922714117","article-title":"A paradigm of thermal adaptation in penguins and elephants by tuning cold activation in TRPM8","volume":"117","author":"Yang","year":"2020","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"1","key":"10.1016\/j.neuroscience.2025.04.044_b0510","doi-asserted-by":"crossref","first-page":"4924","DOI":"10.1038\/s41467-023-40504-6","article-title":"A parabrachial-hypothalamic parallel circuit governs cold defense in mice","volume":"14","author":"Yang","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neuroscience.2025.04.044_b0515","unstructured":"Yousef, H., Ramezanpour-Ahangar, E., Varacallo, M. Physiology, Thermal Regulation. [Updated 2023 May 1]. In: StatPearls [Internet]. StatPearls Publishing, Treasure Island(FL). Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK499843\/."},{"issue":"18","key":"10.1016\/j.neuroscience.2025.04.044_b0520","doi-asserted-by":"crossref","first-page":"5034","DOI":"10.1523\/JNEUROSCI.0213-16.2016","article-title":"Glutamatergic preoptic area neurons that express Leptin receptors drive temperature-dependent body weight homeostasis","volume":"36","author":"Yu","year":"2016","journal-title":"J. Neurosci."},{"issue":"4","key":"10.1016\/j.neuroscience.2025.04.044_b0525","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1007\/s12124-020-09537-0","article-title":"Combination-Sharing theory and sharing rule of regularity","volume":"54","author":"Yu","year":"2020","journal-title":"Integr. Psychol. Behav. Sci."},{"issue":"1","key":"10.1016\/j.neuroscience.2025.04.044_b0530","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s42087-021-00215-0","article-title":"One of nature\u2019s basic laws: Combination-Sharing","volume":"6","author":"Yu","year":"2023","journal-title":"Hu. Arenas"},{"key":"10.1016\/j.neuroscience.2025.04.044_b0535","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2022.1075305","article-title":"Modulation of the thermosensory system by oxytocin","volume":"15","author":"Zayan","year":"2023","journal-title":"Front. Mol. 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