{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T12:23:41Z","timestamp":1780575821834,"version":"3.54.1"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100018936","name":"Qingdao Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["QDBSH20230202039"],"award-info":[{"award-number":["QDBSH20230202039"]}],"id":[{"id":"10.13039\/100018936","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82471459"],"award-info":[{"award-number":["82471459"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020196","name":"Shandong Provincial Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["SDCX-ZG-202400038"],"award-info":[{"award-number":["SDCX-ZG-202400038"]}],"id":[{"id":"10.13039\/501100020196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020196","name":"Shandong Provincial Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["SDBX2023050"],"award-info":[{"award-number":["SDBX2023050"]}],"id":[{"id":"10.13039\/501100020196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2023TQ0165"],"award-info":[{"award-number":["2023TQ0165"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2023 M741857"],"award-info":[{"award-number":["2023 M741857"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ibroneuroscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.neuroscience.2025.05.030","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T05:04:30Z","timestamp":1747717470000},"page":"315-321","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Resting-state fMRI study on male patients with Parkinson\u2019s disease and with sexual dysfunction"],"prefix":"10.1016","volume":"577","author":[{"given":"Kunpeng","family":"Qin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yande","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anmu","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binghui","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2025.05.030_b0005","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0031-6997(24)01503-5","article-title":"Pharmacology of penile erection","volume":"53","author":"Andersson","year":"2001","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0010","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1124\/pr.111.004515","article-title":"Mechanisms of penile erection and basis for pharmacological treatment of erectile dysfunction","volume":"63","author":"Andersson","year":"2011","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0015","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1093\/brain\/awf108","article-title":"Brain activation and sexual arousal in healthy, heterosexual males","volume":"125","author":"Arnow","year":"2002","journal-title":"Brain"},{"key":"10.1016\/j.neuroscience.2025.05.030_b0020","doi-asserted-by":"crossref","first-page":"e5539","DOI":"10.7717\/peerj.5539","article-title":"Autonomic dysfunction and white matter microstructural changes in drug-na\u00efve patients with Parkinson's disease","volume":"6","author":"Ashraf-Ganjouei","year":"2018","journal-title":"PeerJ"},{"key":"10.1016\/j.neuroscience.2025.05.030_b0025","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/S0149-7634(99)00019-6","article-title":"Central inhibition of sexual response in the male: a theoretical perspective","volume":"23","author":"Bancroft","year":"1999","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0030","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.neuroimage.2011.07.013","article-title":"MRI atlas of the human hypothalamus","volume":"59","author":"Baroncini","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroscience.2025.05.030_b0035","doi-asserted-by":"crossref","first-page":"2546","DOI":"10.1111\/j.1743-6109.2011.02376.x","article-title":"Neural bases of hypoactive sexual desire disorder in women: an event-related FMRI study","volume":"8","author":"Bianchi-Demicheli","year":"2011","journal-title":"J. Sex. Med."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0040","doi-asserted-by":"crossref","first-page":"455","DOI":"10.3233\/JPD-202481","article-title":"The \u03b1-Synuclein Origin and Connectome Model (SOC Model) of Parkinson's Disease: Explaining Motor Asymmetry, Non-Motor Phenotypes, and Cognitive Decline","volume":"11","author":"Borghammer","year":"2021","journal-title":"J. Parkinsons Dis."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0045","doi-asserted-by":"crossref","first-page":"S281","DOI":"10.3233\/JPD-191721","article-title":"Brain-First versus Gut-First Parkinson's Disease: A Hypothesis","volume":"9","author":"Borghammer","year":"2019","journal-title":"J. Parkinsons Dis."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0050","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1177\/1756285611411504","article-title":"Management of sexual dysfunction in Parkinson's disease","volume":"4","author":"Bronner","year":"2011","journal-title":"Ther. Adv. Neurol. Disord."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0055","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0105336","article-title":"Brain networks during free viewing of complex erotic movie: new insights on psychogenic erectile dysfunction","volume":"9","author":"Cera","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.neuroscience.2025.05.030_b0060","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/B978-0-12-819973-2.00016-2","article-title":"Lewy bodies in the olfactory system and the hypothalamus","volume":"182","author":"Cersosimo","year":"2021","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0065","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jsxm.2017.11.221","article-title":"Changes in Male Rat Sexual Behavior and Brain Activity Revealed by Functional Magnetic Resonance Imaging in Response to Chronic Mild Stress","volume":"15","author":"Chen","year":"2018","journal-title":"J. Sex. Med."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0070","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1111\/andr.13171","article-title":"Dopamine D2 receptors in the nucleus accumbens modulate erectile function in a rat model of nonorganic erectile dysfunction","volume":"10","author":"Chen","year":"2022","journal-title":"Andrology"},{"key":"10.1016\/j.neuroscience.2025.05.030_b0075","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1016\/j.jsxm.2020.09.002","article-title":"Brain Functional Biomarkers Distinguishing Premature Ejaculation From Anejaculation by ALFF: A Resting-State fMRI Study","volume":"17","author":"Chen","year":"2020","journal-title":"J. Sex. Med."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0080","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/j.2040-4603.2015.tb00605.x","article-title":"Hypothalamus as an endocrine organ","volume":"5","author":"Clarke","year":"2015","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0085","doi-asserted-by":"crossref","first-page":"4769","DOI":"10.1007\/s10072-022-06050-7","article-title":"Striatal dopamine transporter imaging in Parkinson's disease drug-na\u00efve patients: focus on sexual dysfunction","volume":"43","author":"Contaldi","year":"2022","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0090","doi-asserted-by":"crossref","first-page":"4341","DOI":"10.2174\/13816128113199990333","article-title":"The control of male sexual responses","volume":"19","author":"Courtois","year":"2013","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0095","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/0031-9384(93)90179-J","article-title":"Erectile mechanism in paraplegia","volume":"53","author":"Courtois","year":"1993","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0100","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1002\/mds.26868","article-title":"Hypothalamic \u03b1-synuclein and its relation to weight loss and autonomic symptoms in Parkinson's disease","volume":"32","author":"De Pablo-Fernandez","year":"2017","journal-title":"Mov. Disord."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0105","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1177\/08919887211063810","article-title":"Sexual Dysfunction Among Egyptian Idiopathic Parkinson's Disease Patients","volume":"35","author":"Elshamy","year":"2022","journal-title":"J. Geriatr. Psychiatry Neurol."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0110","doi-asserted-by":"crossref","first-page":"3089","DOI":"10.1002\/hbm.20733","article-title":"Men versus women on sexual brain function: prominent differences during tactile genital stimulation, but not during orgasm","volume":"30","author":"Georgiadis","year":"2009","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0115","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1159\/000049844","article-title":"Dopamine and male sexual function","volume":"40","author":"Giuliano","year":"2001","journal-title":"Eur. Urol."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0120","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.parkreldis.2009.10.007","article-title":"Sexual and relationship dysfunction in people with Parkinson's disease","volume":"16","author":"Hand","year":"2010","journal-title":"Parkinsonism Relat. Disord."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0125","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1136\/jnnp.2007.131045","article-title":"Parkinson's disease: clinical features and diagnosis","volume":"79","author":"Jankovic","year":"2008","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.neuroscience.2025.05.030_b0130","doi-asserted-by":"crossref","first-page":"6088","DOI":"10.1002\/hbm.22607","article-title":"Resting-state functional connectivity of the human hypothalamus","volume":"35","author":"Kullmann","year":"2014","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0135","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/ana.410030207","article-title":"The hypothalamus in Parkinson disease","volume":"3","author":"Langston","year":"1978","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0140","article-title":"Altered regional brain activity and functional connectivity in resting-state brain networks associated with psychological erectile dysfunction","volume":"17","author":"Liu","year":"2023","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0145","doi-asserted-by":"crossref","first-page":"9361","DOI":"10.1523\/JNEUROSCI.17-23-09361.1997","article-title":"Extracellular serotonin in the lateral hypothalamic area is increased during the postejaculatory interval and impairs copulation in male rats","volume":"17","author":"Lorrain","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0150","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/j.neuroimage.2008.05.051","article-title":"Activation of mirror-neuron system by erotic video clips predicts degree of induced erection: an fMRI study","volume":"42","author":"Mouras","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroscience.2025.05.030_b0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2022.101665","article-title":"The association between Parkinson's disease and Sexual dysfunction: Clinical correlation and therapeutic implications","volume":"79","author":"Ng","year":"2022","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0160","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1002\/mds.870130326","article-title":"Apomorphine-induced penile erections in Parkinson's disease","volume":"13","author":"O'Sullivan","year":"1998","journal-title":"Mov. Disord."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0165","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/B978-0-444-63247-0.00011-0","article-title":"Sexual dysfunction in patients with peripheral nervous system lesions","volume":"130","author":"Podnar","year":"2015","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0170","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1468-1331.2004.00820.x","article-title":"Pergolide mesylate can improve sexual dysfunction in patients with Parkinson's disease: the results of an open, prospective, 6-month follow-up","volume":"11","author":"Pohanka","year":"2004","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0175","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.bbr.2014.07.037","article-title":"Serotonin in Parkinson's disease","volume":"277","author":"Politis","year":"2015","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0180","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1001\/archneur.1968.00480020070007","article-title":"Penile erection evoked from forebrain structures in Macaca mulatta","volume":"19","author":"Robinson","year":"1968","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0185","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/mds.22519","article-title":"Genitourinary dysfunction in Parkinson's disease","volume":"25","author":"Sakakibara","year":"2010","journal-title":"Mov. Disord."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0190","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s00702-023-02729-z","article-title":"Sexual dysfunction in men with young onset Parkinson's disease","volume":"131","author":"Sandeep","year":"2024","journal-title":"J. Neural Transm. (Vienna)"},{"key":"10.1016\/j.neuroscience.2025.05.030_b0195","article-title":"Sexual Disorders and Quality of Life in Parkinson's Disease","volume":"9","author":"Santa Rosa Malcher","year":"2021","journal-title":"Sex Med"},{"key":"10.1016\/j.neuroscience.2025.05.030_b0200","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1038\/nature04284","article-title":"Hypothalamic regulation of sleep and circadian rhythms","volume":"437","author":"Saper","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2025.05.030_b0205","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1007\/s10072-020-04328-2","article-title":"Sexual dysfunction in male patients with Parkinson's disease: related factors and impact on quality of life","volume":"41","author":"Shalash","year":"2020","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0210","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.tics.2023.08.019","article-title":"The cognitive (lateral) hypothalamus","volume":"28","author":"Sharpe","year":"2024","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0215","doi-asserted-by":"crossref","first-page":"565","DOI":"10.3233\/JPD-230212","article-title":"The Impact of Motor, Non-Motor, and Social Aspects on the Sexual Health of Men Living with Parkinson's Disease","volume":"14","author":"Souza","year":"2024","journal-title":"J. Parkinsons Dis."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0220","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.juro.2006.03.032","article-title":"Brain processing of audiovisual sexual stimuli inducing penile erection: a positron emission tomography study","volume":"176","author":"Tsujimura","year":"2006","journal-title":"J. Urol."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0225","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s13760-022-02086-w","article-title":"Discussing sexual health among Flemish patients with Parkinson's disease","volume":"123","author":"Van Overmeire","year":"2023","journal-title":"Acta Neurol. Belg."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0230","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1002\/mds.26739","article-title":"Sexual dysfunction in women with Parkinson's disease","volume":"31","author":"Varanda","year":"2016","journal-title":"Mov. Disord."},{"key":"10.1016\/j.neuroscience.2025.05.030_b0235","article-title":"Convergent and Divergent Structural Connectivity of Brain White Matter Network Between Patients With Erectile Dysfunction and Premature Ejaculation: A Graph Theory Analysis Study","volume":"13","author":"Zhang","year":"2022","journal-title":"Front. Neurol."}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452225003926?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452225003926?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T06:25:07Z","timestamp":1762410307000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452225003926"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":47,"alternative-id":["S0306452225003926"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2025.05.030","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Resting-state fMRI study on male patients with Parkinson\u2019s disease and with sexual dysfunction","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2025.05.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 International Brain Research Organization (IBRO). Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}