{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T13:59:53Z","timestamp":1791467993161,"version":"4.3.4"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004829","name":"Sichuan Province Department of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ibroneuroscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.neuroscience.2026.06.021","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T16:20:24Z","timestamp":1782404424000},"page":"111-123","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["rno-miR-199a-3p-Nedd4 signaling regulates mast cell-dependent peripheral sensitization in osteoarthritis pain"],"prefix":"10.1016","volume":"611","author":[{"given":"Baitong","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuoyang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinye","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilu","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianhua","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linghuo","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui Yee","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingjun","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenchuan","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanrong","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0005","first-page":"12","article-title":"Anatomy and classification of acupoints","volume":"4","author":"Hwang","year":"1992","journal-title":"Probl. Vet. Med."},{"issue":"10","key":"10.1016\/j.neuroscience.2026.06.021_b0010","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1111\/pme.12761","article-title":"What is the acupoint? A preliminary review of acupoints","volume":"16","author":"Li","year":"2015","journal-title":"Pain Med."},{"issue":"3","key":"10.1016\/j.neuroscience.2026.06.021_b0015","first-page":"199","article-title":"Clinical application of acupoint heat-sensitization","volume":"27","author":"Chen","year":"2007","journal-title":"Zhongguo Zhen Jiu"},{"issue":"11","key":"10.1016\/j.neuroscience.2026.06.021_b0020","first-page":"1203","article-title":"The plasticity of acupoint","volume":"35","author":"Zhu","year":"2015","journal-title":"Zhongguo Zhen Jiu"},{"issue":"3","key":"10.1016\/j.neuroscience.2026.06.021_b0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0194022","article-title":"Mast cells are important regulator of acupoint sensitization via the secretion of tryptase, 5-hydroxytryptamine, and histamine","volume":"13","author":"Ding","year":"2018","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.neuroscience.2026.06.021_b0030","first-page":"395","article-title":"Moxibustion on heat-sensitive acupoints for treatment of myofascial pain syndrome: a multi-central randomized controlled trial","volume":"28","author":"Chen","year":"2008","journal-title":"Zhongguo Zhen Jiu"},{"issue":"6","key":"10.1016\/j.neuroscience.2026.06.021_b0035","first-page":"527","article-title":"Clinical trials for treatment of allergic rhinitis with heat sensitive moxibustion and its regularity of heat-sensitization acupoint distribution","volume":"42","author":"Lin","year":"2017","journal-title":"Zhen Ci Yan Jiu"},{"issue":"12","key":"10.1016\/j.neuroscience.2026.06.021_b0040","first-page":"4039","article-title":"Effect of acupuncture on sensitization of zusanli (ST36) in rats with different functional states","volume":"25","author":"Luo","year":"2023","journal-title":"Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0045","first-page":"16","article-title":"Relationship between the function of mast cells and acupuncture analgesia in adjuvant arthritis rats","volume":"32","author":"Lin","year":"2007","journal-title":"Zhen Ci Yan Jiu"},{"issue":"5","key":"10.1016\/j.neuroscience.2026.06.021_b0050","doi-asserted-by":"crossref","first-page":"511","DOI":"10.7150\/ijbs.8631","article-title":"Mast cell-nerve cell interaction at acupoint: modeling mechanotransduction pathway induced by acupuncture","volume":"10","author":"Yao","year":"2014","journal-title":"Int. J. Biol. Sci."},{"issue":"Supplement 2","key":"10.1016\/j.neuroscience.2026.06.021_b0055","doi-asserted-by":"crossref","first-page":"S73","DOI":"10.1016\/j.jaci.2009.11.017","article-title":"IgE, mast cells, basophils, and eosinophils","volume":"125","author":"Stone","year":"2010","journal-title":"J. Allergy Clin. Immunol."},{"issue":"3","key":"10.1016\/j.neuroscience.2026.06.021_b0060","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s00281-018-0675-z","article-title":"Skin neurogenic inflammation","volume":"40","author":"Choi","year":"2018","journal-title":"Semin. Immunopathol."},{"issue":"5","key":"10.1016\/j.neuroscience.2026.06.021_b0065","first-page":"323","article-title":"Mast cell and substance P are involved in the process of acupoint sensitization induced by acute gastric mucosal injury","volume":"35","author":"Shi","year":"2010","journal-title":"Zhen Ci Yan Jiu"},{"key":"10.1016\/j.neuroscience.2026.06.021_b0070","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2022.974007","article-title":"Shared nociceptive dorsal root ganglion neurons participating in acupoint sensitization","volume":"15","author":"Li","year":"2022","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.neuroscience.2026.06.021_b0075","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.22037.1","article-title":"Recent advances in mast cell activation and regulation","volume":"9","author":"Kim","year":"2020","journal-title":"F1000Res"},{"issue":"9","key":"10.1016\/j.neuroscience.2026.06.021_b0080","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.3390\/ijms20092145","article-title":"MicroRNA involvement in allergic and non-allergic mast cell activation","volume":"20","author":"Shefler","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neuroscience.2026.06.021_b0085","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.nbd.2014.08.003","article-title":"MicroRNAs as modulators and biomarkers of inflammatory and neuropathic pain conditions","volume":"71","author":"Andersen","year":"2014","journal-title":"Neurobiol. Dis."},{"issue":"6","key":"10.1016\/j.neuroscience.2026.06.021_b0090","doi-asserted-by":"crossref","first-page":"6873","DOI":"10.21037\/apm-21-669","article-title":"Effect of intrathecal injection of miRNA-138 on neuropathic pain in rats undergoing partial sciatic nerve ligation and its underlying mechanism","volume":"10","author":"Jin","year":"2021","journal-title":"Annals of Palliative Medicine."},{"key":"10.1016\/j.neuroscience.2026.06.021_b0095","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2020.525144","article-title":"Electroacupuncture promoted nerve repair after peripheral nerve injury by regulating miR-1b and its target brain-derived neurotrophic factor","volume":"14","author":"Liu","year":"2020","journal-title":"Front. Neurosci."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0100","doi-asserted-by":"crossref","DOI":"10.1080\/20013078.2019.1697583","article-title":"Characterization of protein, long noncoding RNA and microRNA signatures in extracellular vesicles derived from resting and degranulated mast cells","volume":"9","author":"Liang","year":"2020","journal-title":"J Extracell Vesicles."},{"issue":"4","key":"10.1016\/j.neuroscience.2026.06.021_b0105","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jmii.2018.10.006","article-title":"Characterization of microRNA profile in IgE-mediated mouse BMMCs degranulation","volume":"53","author":"Li","year":"2020","journal-title":"J. Microbiol. Immunol. Infect."},{"issue":"11","key":"10.1016\/j.neuroscience.2026.06.021_b0110","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0314446","article-title":"Interleukin-33 mediated regulation of microRNAs in human cord blood-derived mast cells: Implications for infection, immunity, and inflammation","volume":"19","author":"Bakhashab","year":"2024","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0115","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s10238-024-01554-2","article-title":"Mast cell-mediated microRNA functioning in immune regulation and disease pathophysiology","volume":"25","author":"Deng","year":"2025","journal-title":"Clin. Exp. Med."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0120","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jtcme.2025.02.001","article-title":"Plasma-derived exosomal miR-144-3p targeting IL-1\u03b2 is involved in pressure pain threshold regulation at PC6 acupoint in myocardial ischemia rats","volume":"16","author":"Li","year":"2025","journal-title":"J. Tradit. Complement. Med."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0125","first-page":"51","article-title":"Revealing characteristics and rules of acupoint sensitization phenomena: based on knee osteoarthritis","volume":"42","author":"Xu","year":"2022","journal-title":"Zhongguo Zhen Jiu"},{"issue":"08","key":"10.1016\/j.neuroscience.2026.06.021_b0130","first-page":"2777","article-title":"Dynamic clinical observation of the characteristics and patterns of pain sensitivity points in patients with knee osteoarthritis","volume":"23","author":"Lin","year":"2021","journal-title":"Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0135","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s13020-022-00626-3","article-title":"Effects of acupuncture at acupoints with lower versus higher pain threshold for knee osteoarthritis: a multicenter randomized controlled trial","volume":"17","author":"Liu","year":"2022","journal-title":"Chin. Med."},{"issue":"12","key":"10.1016\/j.neuroscience.2026.06.021_b0140","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1007\/s11655-022-3588-6","article-title":"Acupuncture enhances signals at sensitized acupoints to elevate pressure pain threshold in knee osteoarthritis patients","volume":"28","author":"Wang","year":"2022","journal-title":"Chin. J. Integr. Med."},{"key":"10.1016\/j.neuroscience.2026.06.021_b0145","series-title":"The clininal observation of acupoint sensitization phenomenon for knee osteoarthritis patients","author":"Zhou","year":"2018"},{"issue":"9","key":"10.1016\/j.neuroscience.2026.06.021_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.prp.2019.152511","article-title":"miR-199a-3p targets ETNK1 to promote invasion and migration in gastric cancer cells and is associated with poor prognosis","volume":"215","author":"Li","year":"2019","journal-title":"Pathology - Research and Practice."},{"issue":"3","key":"10.1016\/j.neuroscience.2026.06.021_b0155","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.explore.2008.02.002","article-title":"Role of mast cells in acupuncture effect: a pilot study","volume":"4","author":"Zhang","year":"2008","journal-title":"EXPLORE"},{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0160","doi-asserted-by":"crossref","first-page":"5738","DOI":"10.1038\/s41598-021-84963-7","article-title":"Higher PGD(2) production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR-199a-3p\/prostaglandin synthetase 2 axis","volume":"11","author":"Mishima","year":"2021","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0165","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jaci.2022.10.003","article-title":"Mast cells in food allergy: Inducing immediate reactions and shaping long-term immunity","volume":"151","author":"Oettgen","year":"2023","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.neuroscience.2026.06.021_b0170","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.bbi.2020.08.016","article-title":"The role of substance P in acupuncture signal transduction and effects","volume":"91","author":"Fan","year":"2021","journal-title":"Brain Behav. Immun."},{"issue":"6","key":"10.1016\/j.neuroscience.2026.06.021_b0175","doi-asserted-by":"crossref","first-page":"3180","DOI":"10.1073\/pnas.051003498","article-title":"Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signaling","volume":"98","author":"Lafont","year":"2001","journal-title":"PNAS"},{"issue":"10","key":"10.1016\/j.neuroscience.2026.06.021_b0180","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1001\/jamainternmed.2019.2407","article-title":"Acupuncture as adjunctive therapy for chronic stable angina: a randomized clinical trial","volume":"179","author":"Zhao","year":"2019","journal-title":"JAMA Intern. Med."},{"key":"10.1016\/j.neuroscience.2026.06.021_b0185","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.2147\/JPR.S256950","article-title":"Effect of electro-acupuncture (EA) and manual acupuncture (MA) on markers of inflammation in knee osteoarthritis","volume":"13","author":"Shi","year":"2020","journal-title":"J. Pain Res."},{"issue":"2","key":"10.1016\/j.neuroscience.2026.06.021_b0190","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1007\/s11655-023-3565-8","article-title":"Electroacupuncture at sensitized acupoints relieves somatic referred pain in colitis rats by inhibiting sympathetic-sensory coupling to interfere with 5-HT signaling pathway","volume":"30","author":"Yang","year":"2023","journal-title":"Chin. J. Integr. Med."},{"issue":"3","key":"10.1016\/j.neuroscience.2026.06.021_b0195","first-page":"211","article-title":"Randomized controlled clinical trial of acupuncture treatment for knee osteoarthritis in the early stage","volume":"44","author":"Luo","year":"2019","journal-title":"Zhen Ci Yan Jiu"},{"issue":"2","key":"10.1016\/j.neuroscience.2026.06.021_b0200","first-page":"99","article-title":"Effect of electroacupuncture and moxibustion pretreatment on expression of cerebral micro-RNAs and Aquaporin protein-4 in cerebral infarction rats","volume":"40","author":"Zheng","year":"2015","journal-title":"Zhen Ci Yan Jiu"},{"key":"10.1016\/j.neuroscience.2026.06.021_b0205","doi-asserted-by":"crossref","first-page":"120","DOI":"10.3389\/fimmu.2012.00120","article-title":"Mast cell: an emerging partner in immune interaction","volume":"3","author":"Gri","year":"2012","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.neuroscience.2026.06.021_b0210","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.4049\/jimmunol.174.3.1153","article-title":"Sphingolipids and the balancing of immune cell function: lessons from the mast cell","volume":"174","author":"Olivera","year":"2005","journal-title":"J. Immunol."},{"issue":"6","key":"10.1016\/j.neuroscience.2026.06.021_b0215","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0158104","article-title":"Isolation of mature (peritoneum-derived) mast cells and immature (bone marrow-derived) mast cell precursors from mice","volume":"11","author":"Meurer","year":"2016","journal-title":"PLoS One"},{"issue":"7974","key":"10.1016\/j.neuroscience.2026.06.021_b0220","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1038\/s41586-023-06188-0","article-title":"Mast cells link immune sensing to antigen-avoidance behaviour","volume":"620","author":"Plum","year":"2023","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0225","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.molimm.2014.01.018","article-title":"Mast cell progenitors: Origin, development and migration to tissues","volume":"63","author":"Dahlin","year":"2015","journal-title":"Mol. Immunol."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0230","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/imr.12634","article-title":"Mast cells as sources of cytokines, chemokines, and growth factors","volume":"282","author":"Mukai","year":"2018","journal-title":"Immunol. Rev."},{"issue":"21","key":"10.1016\/j.neuroscience.2026.06.021_b0235","doi-asserted-by":"crossref","first-page":"13242","DOI":"10.3390\/ijms232113242","article-title":"Mast cell cytokines in acute and chronic gingival tissue inflammation: role of IL-33 and IL-37","volume":"23","author":"Trimarchi","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.neuroscience.2026.06.021_b0240","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1152\/physrev.1997.77.4.1033","article-title":"Mast cells","volume":"77","author":"Metcalfe","year":"1997","journal-title":"Physiol. Rev."},{"issue":"10","key":"10.1016\/j.neuroscience.2026.06.021_b0245","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1369\/0022155414545334","article-title":"Mast cell function: a new vision of an old cell","volume":"62","author":"Da Silva","year":"2014","journal-title":"Journal of Histochemistry & Cytochemistry."},{"issue":"7","key":"10.1016\/j.neuroscience.2026.06.021_b0250","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1365-2044.2004.03757.x","article-title":"Mast cell tryptase: a review of its physiology and clinical significance","volume":"59","author":"Payne","year":"2004","journal-title":"Anaesthesia"},{"issue":"6","key":"10.1016\/j.neuroscience.2026.06.021_b0255","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/nrm2690","article-title":"Physiological functions of the HECT family of ubiquitin ligases","volume":"10","author":"Rotin","year":"2009","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"6","key":"10.1016\/j.neuroscience.2026.06.021_b0260","doi-asserted-by":"crossref","DOI":"10.1002\/jbio.201800458","article-title":"Lack of association between acupoint sensitization and microcirculatory structural changes in a mouse model of knee osteoarthritis: a pilot study","volume":"12","author":"Ding","year":"2019","journal-title":"J. Biophotonics"},{"key":"10.1016\/j.neuroscience.2026.06.021_b0265","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.neuroscience.2019.02.028","article-title":"Acupoint sensitization is associated with increased excitability and hyperpolarization-activated current (Ih) in C- but not A\u03b4-Type neurons","volume":"404","author":"Zhang","year":"2019","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2026.06.021_b0270","first-page":"1","article-title":"Hypoxia-induced glioma-derived exosomal miRNA-199a-3p promotes ischemic injury of peritumoral neurons by inhibiting the mTOR pathway","volume":"2020","author":"Zhao","year":"2020","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"12","key":"10.1016\/j.neuroscience.2026.06.021_b0275","doi-asserted-by":"crossref","first-page":"23736","DOI":"10.1002\/jcp.28941","article-title":"Exosomes from human-bone-marrow-derived mesenchymal stem cells protect against renal ischemia\/reperfusion injury via transferring miR-199a-3p","volume":"234","author":"Zhu","year":"2019","journal-title":"J. Cell. Physiol."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0280","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1186\/s13287-021-02148-5","article-title":"Umbilical mesenchymal stem cell-derived exosomes facilitate spinal cord functional recovery through the miR-199a-3p\/145-5p-mediated NGF\/TrkA signaling pathway in rats","volume":"12","author":"Wang","year":"2021","journal-title":"Stem Cell Res Ther"},{"issue":"1","key":"10.1016\/j.neuroscience.2026.06.021_b0285","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1186\/s12951-023-02086-9","article-title":"Engineering exosomes derived from subcutaneous fat MSCs specially promote cartilage repair as miR-199a-3p delivery vehicles in Osteoarthritis","volume":"21","author":"Zhao","year":"2023","journal-title":"J. Nanobiotechnol."}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452226004082?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452226004082?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T13:19:05Z","timestamp":1791465545000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452226004082"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":57,"alternative-id":["S0306452226004082"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2026.06.021","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"rno-miR-199a-3p-Nedd4 signaling regulates mast cell-dependent peripheral sensitization in osteoarthritis pain","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2026.06.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 International Brain Research Organization (IBRO). Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}